Brief Information of the Cell Line and Protein
Cell Line ID: CL000025 , HEK-293T
 Cell Line Info 
Synonyms
Hek293T
HEK-293T
HEK 293T
HEK-293-T
HEK 293 T
293-T
293 T
293T
Human Embryonic Kidney 293T
293tsA1609neo
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0063
Protein ID: PT00922 , Epidermal growth factor receptor
 Protein Info 
Gene Name EGFR
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P00533
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000025
 Cell Line Info 
 Protein ID: PT00922
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0325284
 Compound Info 
N-[3-[[4-[5-(4-fluorophenyl)-2-methylsulfanyl-1H-imidazol-4-yl]pyridin-2-yl]amino]-4-methoxyphenyl]prop-2-enamide
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C25H22FN5O2S
  1
1
IC50 = 330 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0568100
 Compound Info 
N-[3-[5-(2-acetamidopyridin-4-yl)-2-methylsulfanyl-1H-imidazol-4-yl]phenyl]-2-fluoro-5-hydroxybenzamide
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C24H20FN5O3S
  1
1
IC50 = 330 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0033646
 Compound Info 
AZD-9291
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C28H33N7O2
  1
1
IC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0569341
 Compound Info 
2-[(1,3-dioxoisoindol-2-yl)methyl]-6-fluoro-3-hydroxy-N-[3-[5-[2-[2-methoxy-5-(prop-2-enoylamino)anilino]pyridin-4-yl]-2-methylsulfanyl-1H-imidazol-4-yl]phenyl]benzamide
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C41H32FN7O6S
  1
1
IC50 = 6700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0076102
 Compound Info 
2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide
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C19H14FN3O3S
  1
1
IC50 = 15000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0544962
 Compound Info 
N-[3-[5-(2-acetamidopyridin-4-yl)-2-methylsulfanyl-1H-imidazol-4-yl]phenyl]-2-[(1,3-dioxoisoindol-2-yl)methyl]-6-fluoro-3-hydroxybenzamide
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C33H25FN6O5S
  1
1
IC50 > 40000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0544963
 Compound Info 
N-[3-[5-(2-acetamidopyridin-4-yl)-2-methylsulfanyl-1H-imidazol-4-yl]phenyl]-6-fluoro-3-hydroxy-2-[(3-oxo-1H-isoindol-2-yl)methyl]benzamide
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C33H27FN6O4S
  1
1
IC50 > 40000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS