Brief Information of the Cell Line and Protein
Cell Line ID: CL000023 , BTI-Tn-5B1-4
 Cell Line Info 
Synonyms
BTI-TN-5B1-4
BTI-TN5B1-4
BTI-Tn5B14
BTI-Tn 5B1-4
Tn-5B1-4
Tn 5B1-4
Tn5 B1-4
Tn5B1-4
TN5B14
TnH5
High Five
High 5
High-5
High5
Hi-five
Hi-5
Hi5
Tn-5
Category Spontaneously immortalized cell line
Organism
Trichoplusia ni (Cabbage looper)
Cellosaurus ID
CVCL_C190
Protein ID: PT05838 , Prostaglandin E synthase
 Protein Info 
Gene Name PTGES
Organism Mus musculus, Mouse
Protein Classification Enzyme
Uniprot ID Q9JM51
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000023
 Cell Line Info 
 Protein ID: PT05838
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0561868
 Compound Info 
(3S)-3-[3-[[2-cyclopentyl-2-[4-[5-(2-methylpropyl)pyridin-3-yl]phenyl]acetyl]amino]-2-methylphenyl]pentanoic acid
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C34H42N2O3
  1
1
IC50 = 84 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0467908
 Compound Info 
3-[3-[[2-cyclopentyl-2-[4-[5-(2-methylpropyl)pyridin-3-yl]phenyl]acetyl]amino]-2-methylphenyl]propanoic acid
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C32H38N2O3
  1
1
IC50 = 191 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0469453
 Compound Info 
(3S)-3-[3-[[2-cyclopentyl-2-[4-(5-ethylpyridin-3-yl)phenyl]acetyl]amino]-2-methylphenyl]pentanoic acid
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C32H38N2O3
  1
1
IC50 = 203 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0467892
 Compound Info 
(3R)-3-[3-[[(2R)-2-[4-(5-chloropyridin-3-yl)phenyl]-2-cyclopentylacetyl]amino]-2-methylphenyl]butanoic acid
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C29H31ClN2O3
  1
1
IC50 = 339 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0529749
 Compound Info 
(3S)-3-[3-[[(2R)-2-[4-(5-chloropyridin-3-yl)phenyl]-2-cyclopentylacetyl]amino]-2-methylphenyl]butanoic acid
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C29H31ClN2O3
  1
1
IC50 = 584 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0519262
 Compound Info 
(−) (R) 3-[3-({[4-(5-Chloropyridin-3-yl)phenyl](cyclopentyl)acetyl}amino)-2-methylphenyl]propanoic acid
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C28H29ClN2O3
  1
1
IC50 = 765 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0537969
 Compound Info 
(R/S) 3-[3- ({Cyclopentyl[4-(5- methylpyridin-3-yl)- phenyl]acetyl}amino)-2- methylphenyl]propanoic acid
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C29H32N2O3
  1
1
IC50 = 818 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0570946
 Compound Info 
(3R)-3-[3-[[(2S)-2-[4-(5-chloropyridin-3-yl)phenyl]-2-cyclopentylacetyl]amino]-2-methylphenyl]butanoic acid
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C29H31ClN2O3
  1
1
IC50 = 3080 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0570950
 Compound Info 
(3S)-3-[3-[[(2S)-2-[4-(5-chloropyridin-3-yl)phenyl]-2-cyclopentylacetyl]amino]-2-methylphenyl]butanoic acid
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C29H31ClN2O3
  1
1
IC50 = 12600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS