Brief Information of the Cell Line and Protein
Cell Line ID: CL000023 , BTI-Tn-5B1-4
Synonyms
BTI-TN-5B1-4
BTI-TN5B1-4
BTI-Tn5B14
BTI-Tn 5B1-4
Tn-5B1-4
Tn 5B1-4
Tn5 B1-4
Tn5B1-4
TN5B14
TnH5
High Five
High 5
High-5
High5
Hi-five
Hi-5
Hi5
Tn-5
Category Spontaneously immortalized cell line
Organism
Trichoplusia ni (Cabbage looper)
Cellosaurus ID
CVCL_C190
Protein ID: PT04206 , DNA (cytosine-5)-methyltransferase 3B
Gene Name DNMT3B
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID Q9UBC3
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000023  Protein ID: PT04206
 
Compound ID Compound Name Compound Formula
CP0011023
AdoHcy
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C14H20N6O5S
 1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
CP0429609
(2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfanyl]butanoic acid
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C15H21N5O5S
 1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
CP0281849
(2-amino-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)ethylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylthio)butanoic acid)
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C28H32N6O5S
 1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
CP0498808
2-amino-4-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(3-phenylpropylamino)-9H-purin-9-yl)-tetrahydrofuran-2-yl)methylthio)butanoic acid
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C23H30N6O5S
 1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS
CP0475851
4-(((2S,3S,4R,5R)-5-(6-(3,5-dimethoxybenzylamino)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl)methylthio)-2-aminobutanoic acid
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C23H30N6O7S
 1
1
IC50 = 900 nM
   TI
   LI
   LO
   TS
CP0397034
2-amino-4-(((2S,3S,4R,5R)-5-(6-(benzylamino)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl)methylthio)butanoic acid
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C21H26N6O5S
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0429610
2-amino-4-(((2S,3S,4R,5R)-5-(6-amino-2-methyl-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl)methylthio)butanoic acid
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C15H22N6O5S
 1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
CP0429615
2-amino-4-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-yl)methylthio)butanoic acid
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C20H24N6O5S
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0457502
2-amino-4-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(phenethylamino)-9H-purin-9-yl)-tetrahydrofuran-2-yl)methylthio)butanoic acid
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C22H28N6O5S
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0429613
2-amino-4-(((2S,3S,4R,5R)-5-(7-amino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl)methylthio)butanoic acid
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C13H19N7O5S
 1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0455272
2-amino-4-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(pyridin-4-ylmethylamino)-9H-purin-9-yl)-tetrahydrofuran-2-yl)methylthio)butanoic acid
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C20H25N7O5S
 1
1
IC50 = 3600 nM
   TI
   LI
   LO
   TS
CP0338078
2-amino-4-(((2S,3S,4R,5R)-5-(6-amino-2-fluoro-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl)methylthio)butanoic acid
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C14H19FN6O5S
 1
1
IC50 = 6800 nM
   TI
   LI
   LO
   TS
CP0457501
2-amino-4-(((2S,3S,4R,5R)-5-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl)methylthio)butanoic acid
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C15H21N5O5S
 1
1
IC50 = 6800 nM
   TI
   LI
   LO
   TS
CP0429611
(2S)-2-amino-4-[[(2S,3S,4R,5R)-3,4-dihydroxy-5-purin-9-yloxolan-2-yl]methylsulfanyl]butanoic acid
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C14H19N5O5S
 1
1
IC50 = 28000 nM
   TI
   LI
   LO
   TS
CP0455274
2-Amino-4-{(2S,3S,4R,5R)-5-[6-(2-biphenyl-4-yl-ethylamino)-2-chloro-purin-9-yl]-3,4-dihydroxy-tetrahydro-furan-2-ylmethylsulfanyl}-butyric acid
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C28H31ClN6O5S
 1
1
IC50 = 29000 nM
   TI
   LI
   LO
   TS
CP0492257
2-amino-4-(((2S,3S,4R,5R)-5-(7-amino-3H-imidazo[4,5-b]pyridin-3-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl)methylthio)butanoic acid
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C15H21N5O5S
 1
1
IC50 = 45000 nM
   TI
   LI
   LO
   TS
CP0302399
2-amino-4-(((2S,3S,4R,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl)methylthio)butanoic acid
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C14H19ClN6O5S
 1
1
IC50 = 57200 nM
   TI
   LI
   LO
   TS