| Compound ID |
Compound Name |
Compound Formula |
|
CP0382558
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-6-sulfonic acid amide
Show/Hide
|
C11H10FN5O2S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0538425
|
US8754233, 5-(3-Amino-propyl)-4-benzothiazol-2-yl-2H-pyrazol-3-ylamine
Show/Hide
|
C13H15N5S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0573513
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid amide
Show/Hide
|
C11H11N5O2S2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0391497
|
US8754233, 2-(3-Amino-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-6-sulfonic acid amide
Show/Hide
|
C10H8FN5O2S2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0538428
|
US8754233, N3-(2-Amino-ethyl)-4-benzothiazol-2-yl-1H-pyrazole-3,5-diamine
Show/Hide
|
C12H14N6S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0566659
|
US8754233, 4-Benzothiazol-2-yl-5-(3-methylamino-propyl)-2H-pyrazol-3-ylamine
Show/Hide
|
C14H17N5S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0951312
|
2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid(acetic hydrazido)amide
Show/Hide
|
C13H14N6O3S2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0403644
|
US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-6-sulfonic acid methylamide
Show/Hide
|
C12H12FN5O2S2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0524256
|
US8754233, 4-(5-Fluoro-benzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine
Show/Hide
|
C11H9FN4S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0544481
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid(pyridin-4-ylmethyl)-amide
Show/Hide
|
C17H16N6O2S2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0549372
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-4-fluorobenzothiazole-6-sulfonic acid amide
Show/Hide
|
C11H10FN5O2S2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0566366
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-furan-2-yl-2H-pyrazol-3-ylamine
Show/Hide
|
C15H11FN4O2S
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0391494
|
US8754233, 4-(5-Fluoro-6-methyl-benzothiazol-2-yl)-2H-pyrazol-3-ylamine
Show/Hide
|
C11H9FN4S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0524283
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-6-sulfonicacid (2-hydroxy-ethyl)-amide
Show/Hide
|
C13H14FN5O3S2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0538638
|
US8754233, 2-(5-Amino-3-pyridin-4-yl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acidamide
Show/Hide
|
C15H12N6O2S2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0389337
|
US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-6-carboxylic acid methyl ester
Show/Hide
|
C13H11FN4O2S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0524258
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-methyl-1H-pyrazol-3-ylamine
Show/Hide
|
C12H11FN4OS
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0573514
|
US8754233, 2-(5-Amino-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid methylamide
Show/Hide
|
C11H11N5O2S2
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0574147
|
US8754233, 4-Benzothiazol-2-yl-5-piperidin-4-yl-2H-pyrazol-3-ylamine
Show/Hide
|
C15H17N5S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0540606
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-piperazin-1-yl-2H-pyrazol-3-ylamine
Show/Hide
|
C15H17FN6OS
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0545229
|
US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid methyl amide
Show/Hide
|
C12H13N5O2S2
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0566368
|
US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-4,5,6-trifluoro-benzothiazole-7-sulfonic acid amide
Show/Hide
|
C11H8F3N5O2S2
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0544482
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid(2,2,2-trifluoro-ethyl)-amide
Show/Hide
|
C13H12F3N5O2S2
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0382556
|
US8754233, 2-{[2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazol-6-ylmethyl]-amino}-ethanol
Show/Hide
|
C14H17N5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0391496
|
US8754233, 5-(4-Amino-phenyl)-4-benzothiazol-2-yl-2H-pyrazol-3-ylamine
Show/Hide
|
C16H13N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0414078
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-isoxazol-5-yl-2H-pyrazol-3-ylamine
Show/Hide
|
C14H10FN5O2S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0419802
|
US8754233, [2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-5-fluoro-benzothiazol-6-yl]-methanol
Show/Hide
|
C12H11FN4OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0527448
|
US8754233, 4-Benzothiazol-2-yl-5-(4-methylamino-butyl)-2H-pyrazol-3-ylamine
Show/Hide
|
C15H19N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0527450
|
US8754233, 4-Benzothiazol-2-yl-5-pyridin-4-yl-2H-pyrazol-3-ylamine
Show/Hide
|
C15H11N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0566661
|
US8754233, 4-Benzothiazol-2-yl-5-furan-2-yl-2H-pyrazol-3-ylamine
Show/Hide
|
C14H10N4OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0545228
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-6-sulfonic acid (pyridin-4-ylmethyl)-amide
Show/Hide
|
C17H15FN6O2S2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0407710
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-4-sulfonicacid (2-hydroxy-ethyl)-amide
Show/Hide
|
C13H14FN5O3S2
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0468184
|
US8754233, 4-Benzothiazol-2-yl-N3-(2-ethylamino-ethyl)-1H-pyrazole-3,5-diamine
Show/Hide
|
C14H18N6S
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0470056
|
US8754233, 4-Benzothiazol-2-yl-5-piperazin-1-yl-2H-pyrazol-3-ylamine
Show/Hide
|
C14H16N6S
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0382557
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid [2-(3H-imidazol-4-yl)-ethyl]-amide
Show/Hide
|
C16H17N7O2S2
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0389333
|
US8754233, 4-(6-Bromo-5-fluoro-benzothiazol-2-yl)-5-methyl-1H-pyrazol-3-ylamine
Show/Hide
|
C11H8BrFN4S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0409755
|
US8754233, 4-(6-Fluoro-benzothiazol-2-yl)-1H-pyrazol-3-ylamine
Show/Hide
|
C10H7FN4S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0414061
|
US8754233, 4-(6-Methoxy-benzothiazol-2-yl)-5-piperazin-1-yl-2H-pyrazol-3-ylamine
Show/Hide
|
C15H18N6OS
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0524261
|
US8754233, N3-(3-Dimethylamino-propyl)-4-(5-fluoro-6-methoxy-benzothiazol-2-yl)-1H-pyrazole-3,5-diamine
Show/Hide
|
C16H21FN6OS
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0546107
|
US8754233, (4-Benzothiazol-2-yl-1H-pyrazol-3-yl)-[2-(1H-imidazol-4-yl)-ethyl]-amine
Show/Hide
|
C15H14N6S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0546568
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-N3-[2-(3H-imidazol-4-yl)-ethyl]-1H-pyrazole-3,5-diamine
Show/Hide
|
C16H16FN7OS
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0546569
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-pyridin-4-yl-2H-pyrazol-3-ylamine
Show/Hide
|
C16H12FN5OS
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0547948
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazol-5-ol
Show/Hide
|
C11H10N4OS
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0549369
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid [2-(4-amino-phenyl)-ethyl]-amide
Show/Hide
|
C19H20N6O2S2
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0560325
|
US8754233, 4-(6-Dimethylaminomethyl-benzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine
Show/Hide
|
C14H17N5S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0560328
|
US8754233, 5-Methyl-4-(4,5,6-trifluoro-benzothiazol-2-yl)-1H-pyrazol-3-ylamine
Show/Hide
|
C11H7F3N4S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0566656
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid (2-hydroxy-ethyl)-amide
Show/Hide
|
C13H15N5O3S2
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0566658
|
US8754233, 4-Benzothiazol-2-yl-5-(3-dimethylamino-propyl)-2H-pyrazol-3-ylamine
Show/Hide
|
C15H19N5S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0574141
|
US8754233, 3-(5-Amino-4-benzothiazol-2-yl-1H-pyrazol-3-yl)-propan-1-ol
Show/Hide
|
C13H14N4OS
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0463184
|
US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-benzothiazole-6-carboxylic acid methyl ester
Show/Hide
|
C13H12N4O2S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0474733
|
US8754233, 4-(5-Fluoro-6-methyl-benzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine
Show/Hide
|
C12H11FN4S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0524260
|
US8754233, N3-(2-Dimethylamino-ethyl)-4-(5-fluoro-6-methoxy-benzothiazol-2-yl)-1H-pyrazole-3,5-diamine
Show/Hide
|
C15H19FN6OS
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0538910
|
US8754233, 4-Benzothiazol-2-yl-5-methyl-1H-pyrazol-3-ylamine
Show/Hide
|
C11H10N4S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0540607
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-(5-nitro-furan-2-yl)-2H-pyrazol-3-ylamine
Show/Hide
|
C15H10FN5O4S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0545230
|
US8754233, 4-Benzothiazol-2-yl-1H-pyrazol-3-ylamine
Show/Hide
|
C10H8N4S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0549371
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-carboxylic acid amide
Show/Hide
|
C12H11N5OS
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0559970
|
US8754233, 4-Benzothiazol-2-yl-N3-(3-dimethylamino-propyl)-1H-pyrazole-3,5-diamine
Show/Hide
|
C15H20N6S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0560326
|
US8754233, 4-(6-Chlorobenzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine
Show/Hide
|
C11H9ClN4S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0573512
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid (2-dimethylamino-ethyl)-amide
Show/Hide
|
C15H20N6O2S2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0544737
|
US8754233, 4-(6-Methoxy-benzothiazol-2-yl)-5-methyl-1H-pyrazol-3-ylamine
Show/Hide
|
C12H12N4OS
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0409768
|
US8754233, 4-(6-Fluoro-benzothiazol-2-yl)-5-methyl-1H-pyrazol-3-ylamine
Show/Hide
|
C11H9FN4S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0409769
|
US8754233, 4-(6-Bromo-benzothiazol-2-yl)-5-methyl-1H-pyrazol-3-ylamine
Show/Hide
|
C11H9BrN4S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0416415
|
US8754233, 4-(4-fluorobenzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine
Show/Hide
|
C11H9FN4S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0524254
|
US8754233, 4-(7-Chloro-5-fluoro-6-methoxy-benzothiazol-2-yl)-5-methyl-1H-pyrazol-3-ylamine
Show/Hide
|
C12H10ClFN4OS
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0527447
|
US8754233, 4-Benzothiazol-2-yl-5-(4-dimethylamino-butyl)-2H-pyrazol-3-ylamine
Show/Hide
|
C16H21N5S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0538099
|
US8754233, N-[2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazol-6-yl]-acetamide
Show/Hide
|
C13H13N5OS
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0544426
|
US8754233, 2-(5-Amino-4-benzothiazol-2-yl-1H-pyrazol-3-ylamino)-ethanol
Show/Hide
|
C12H13N5OS
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0546836
|
US8754233, 3-(5-Amino-4-benzothiazol-2-yl-1H-pyrazol-3-ylamino)-propan-1-ol
Show/Hide
|
C13H15N5OS
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0389334
|
US8754233, 5-Methyl-4-(6-morpholin-4-ylmethyl-benzothiazol-2-yl)-2H-pyrazol-3-ylamine
Show/Hide
|
C16H19N5OS
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0456476
|
US8754233, 4-(6-Methanesulfonyl-benzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine
Show/Hide
|
C12H12N4O2S2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0474456
|
US8754233, 3-[5-Amino-4-(5-fluoro-6-methoxy-benzothiazol-2-yl)-1H-pyrazol-3-ylamino]-propan-1-ol
Show/Hide
|
C14H16FN5O2S
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0538429
|
US8754233, 2-(1H-Pyrazol-4-yl)-benzothiazole-6-sulfonic acid amide
Show/Hide
|
C10H8N4O2S2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0538908
|
US8754233, 2-(5-Amino-1H-pyrazol-4-yl)-benzothiazol-6-ylamine
Show/Hide
|
C10H9N5S
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0538911
|
US8754233, 4-Benzothiazol-2-yl-N3-(2-dimethylamino-ethyl)-1H-pyrazole-3,5-diamine
Show/Hide
|
C14H18N6S
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0540608
|
US8754233, 5-Methyl-4-(6-methylaminomethyl-benzothiazol-2-yl)-2H-pyrazol-3-ylamine
Show/Hide
|
C13H15N5S
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0547950
|
US8754233, 4-Benzothiazol-2-yl-N3-(3-imidazol-1-yl-propyl)-1H-pyrazole-3,5-diamine
Show/Hide
|
C16H17N7S
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0462798
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid (2-methoxy-ethyl)-amide
Show/Hide
|
C14H17N5O3S2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0527449
|
US8754233, 4-Benzothiazol-2-yl-5-cyclopropyl-2H-pyrazol-3-ylamine
Show/Hide
|
C13H12N4S
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0538639
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid 4-amino-benzylamide
Show/Hide
|
C18H18N6O2S2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0538904
|
US8754233, N3-[2-(3H-Imidazol-4-yl)-ethyl]-4-(6-methoxy-benzothiazol-2-yl)-1H-pyrazole-3,5-diamine
Show/Hide
|
C16H17N7OS
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0540593
|
US8754233, 4-(6-Dimethylaminomethyl-5-fluoro-benzothiazol-2-yl)-5-methyl-1H-pyrazol-3-ylamine
Show/Hide
|
C14H16FN5S
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0547949
|
US8754233, 4-Benzothiazol-2-yl-5-pyridin-3-yl-2H-pyrazol-3-ylamine
Show/Hide
|
C15H11N5S
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0541471
|
US8754233, N-{2-[2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonylamino]-ethyl}-acetamide
Show/Hide
|
C15H18N6O3S2
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0548111
|
US8754233, 4-Benzothiazol-2-yl-N3-(2-methoxy-ethyl)-1H-pyrazole-3,5-diamine
Show/Hide
|
C13H15N5OS
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0549233
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-thiophen-2-yl-2H-pyrazol-3-ylamine
Show/Hide
|
C15H11FN4OS2
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0549368
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid cyclopropylmethyl-amide
Show/Hide
|
C15H17N5O2S2
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0566657
|
US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-benzothiazole-7-carboxylic acid methyl ester
Show/Hide
|
C13H12N4O2S
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0573515
|
US8754233, 4-Benzothiazol-2-yl-1H-pyrazole-3,5-diamine
Show/Hide
|
C10H9N5S
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0407708
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acidphenethyl-amide
Show/Hide
|
C19H19N5O2S2
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0416416
|
US8754233, 3-{[2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazol-6-ylmethyl]-amino}-benzenesulfonamide
Show/Hide
|
C18H18N6O2S2
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0470055
|
US8754233, 4-Benzothiazol-2-yl-5-ethyl-1H-pyrazol-3-ylamine
Show/Hide
|
C12H12N4S
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0538615
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acidbenzylamide
Show/Hide
|
C18H17N5O2S2
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0419744
|
US8754233, 4-Benzothiazol-2-yl-5-phenyl-1H-pyrazol-3-ylamine
Show/Hide
|
C16H12N4S
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0538426
|
US8754233, 5-Methyl-4-(6-pyrrolidin-1-ylmethyl-benzothiazol-2-yl)-2H-pyrazol-3-ylamine
Show/Hide
|
C16H19N5S
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0538905
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-(3-nitro-phenyl)-2H-pyrazol-3-ylamine
Show/Hide
|
C17H12FN5O3S
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0546571
|
US8754233, [2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazol-6-yl]-methanol
Show/Hide
|
C12H12N4OS
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0549370
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid 4-chloro-benzylamide
Show/Hide
|
C18H16ClN5O2S2
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0549373
|
US8754233, 2-(3-Methyl-1H-pyrazol-4-yl)-benzothiazole
Show/Hide
|
C11H9N3S
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0574180
|
US8754233, 4-Benzothiazol-2-yl-5-thiophen-2-yl-2H-pyrazol-3-ylamine
Show/Hide
|
C14H10N4S2
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0946752
|
2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid(phenylhydrazino)amide
Show/Hide
|
C17H16N6O2S2
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0472425
|
US8754233, 4-(5-Amino-4-benzothiazol-2-yl-1H-pyrazol-3-yl)-butan-1-ol
Show/Hide
|
C14H16N4OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0524259
|
US8754233, 5-Cyclopropyl-4-(5-fluoro-6-methoxy-benzothiazol-2-yl)-2H-pyrazol-3-ylamine
Show/Hide
|
C14H13FN4OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0538907
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid 4-methoxy-benzylamide
Show/Hide
|
C19H19N5O3S2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0566365
|
US8754233, 4-(7-chloro-4-methoxy-benzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine
Show/Hide
|
C12H11ClN4OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0967549
|
US8754233, 4-Benzothiazol-2-yl-N3-(1H-imidazol-2-ylmethylene)-1H-pyrazole-3,5-diamine
Show/Hide
|
C14H11N7S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0389335
|
US8754233, N-[2-(5-Amino-4-benzothiazol-2-yl-1H-pyrazol-3-ylamino)-ethyl]-acetamide
Show/Hide
|
C14H16N6OS
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0474735
|
US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-benzothiazole-6-carboxylic acid
Show/Hide
|
C12H10N4O2S
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0545231
|
US8754233, 4-Benzothiazol-2-yl-5-methylsulfanyl-1H-pyrazol-3-ylamine
Show/Hide
|
C11H10N4S2
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0560327
|
US8754233, 4-(5-Trifluoromethyl-benzothiazol-2-yl)-1H-pyrazol-3-ylamine
Show/Hide
|
C11H7F3N4S
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0954256
|
4-Benzothiazol-2-yl-N5-(2-morpholin-4-yl-ethyl)-1H-pyrazole-3,5-diamine
Show/Hide
|
C16H20N6OS
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0409770
|
US8754233, 2-(1H-Pyrazol-4-yl)-benzothiazole
Show/Hide
|
C10H7N3S
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0474734
|
US8754233, N-[4-(5-Amino-4-benzothiazol-2-yl-1H-pyrazol-3-yl)-phenyl]-hydroxylamine
Show/Hide
|
C16H13N5OS
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0462796
|
US8754233, 4-(5-Amino-4-benzothiazol-2-yl-1H-pyrazol-3-ylamino)-butan-1-ol
Show/Hide
|
C14H17N5OS
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0550851
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid (2-thiophen-2-yl-ethyl)-amide
Show/Hide
|
C17H17N5O2S3
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0861444
|
4-Benzothiazol-2-yl-N5-ethyl-1H-pyrazole-3,5-diamine
Show/Hide
|
C12H13N5S
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0935553
|
(4-Benzothiazol-2-yl-2H-pyrazol-3-yl)-methyl-amine
Show/Hide
|
C11H10N4S
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0546570
|
US8754233, N-{2-[5-Amino-4-(5-fluoro-6-methoxy-benzothiazol-2-yl)-1H-pyrazol-3-ylamino]-ethyl}-acetamide
Show/Hide
|
C15H17FN6O2S
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0407707
|
US8754233, 4-(4-Benzothiazol-2-yl-1H-pyrazol-3-yl)-6-ethyl-benzene-1,3-diol
Show/Hide
|
C18H15N3O2S
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0407709
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-5-sulfonic acid methyl amide
Show/Hide
|
C12H13N5O2S2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0538912
|
US8754233, 4-Benzothiazol-2-yl-N3-(2-pyrrolidin-1-yl-ethyl)-1H-pyrazole-3,5-diamine
Show/Hide
|
C16H20N6S
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0403645
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-(4-methoxy-phenyl)-2H-pyrazol-3-ylamine
Show/Hide
|
C18H15FN4O2S
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0573510
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-(2-phenyl-cyclopropyl)-2H-pyrazol-3-ylamine
Show/Hide
|
C20H17FN4OS
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0524257
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-phenyl-2H-pyrazol-3-ylamine
Show/Hide
|
C17H13FN4OS
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0538906
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-(3-fluoro-phenyl)-2H-pyrazol-3-ylamine
Show/Hide
|
C17H12F2N4OS
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0572565
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-(4-fluoro-phenyl)-2H-pyrazol-3-ylamine
Show/Hide
|
C17H12F2N4OS
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0470057
|
US8754233, 4-Benzothiazol-2-yl-N3-(1H-imidazol-2-ylmethyl)-1H-pyrazole-3,5-diamine
Show/Hide
|
C14H13N7S
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0558185
|
US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid (2,6-dimethyl-pyrimidin-4-yl)-amide
Show/Hide
|
C17H17N7O2S2
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0574181
|
US8754233, 4-Benzothiazol-2-yl-N3-piperidin-4-ylmethyl-1H-pyrazole-3,5-diamine
Show/Hide
|
C16H20N6S
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0456477
|
US8754233, 5-Methyl-4-(5-trifluoromethylbenzothiazol-2-yl)-1H-pyrazol-3-ylamine
Show/Hide
|
C12H9F3N4S
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0414060
|
US8754233, 4-[2-(5-Amino-4-benzothiazol-2-yl-1H-pyrazol-3-ylamino)-ethyl]-phenol
Show/Hide
|
C18H17N5OS
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
|
CP0566364
|
US8754233, 4-[(5-Amino-4-benzothiazol-2-yl-1H-pyrazol-3-ylamino)-methyl]-benzenesulfonamide
Show/Hide
|
C17H16N6O2S2
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
|
CP0849217
|
4-Benzothiazol-2-yl-N5-pyridin-3-ylmethyl-1H-pyrazole-3,5-diamine
Show/Hide
|
C16H14N6S
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
|
CP0547946
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid (2-morpholin-4-yl-ethyl)-amide
Show/Hide
|
C17H22N6O3S2
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0547945
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid (3-dimethylamino-propyl)-amide
Show/Hide
|
C16H22N6O2S2
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
|
CP0419745
|
US8754233, 4-Benzothiazol-2-yl-N3-[2-(1H-indol-3-yl)-ethyl]-1H-pyrazole-3,5-diamine
Show/Hide
|
C20H18N6S
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0463446
|
(4E)-4-[4-(1,3-benzothiazol-2-yl)-1,2-dihydropyrazol-3-ylidene]-3-hydroxy-1-cyclohexa-2,5-dienone
Show/Hide
|
C16H11N3O2S
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0402866
|
US8754233, 4-(6-Nitro-benzothiazol-2-yl)-2H-pyrazol-3-ylamine
Show/Hide
|
C10H7N5O2S
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0546835
|
US8754233, 4-(4-Benzothiazol-2-yl-1H-pyrazol-3-yl)-phenol
Show/Hide
|
C16H11N3OS
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0560324
|
US8754233, 5-(2-Chloro-pyridin-3-yl)-4-(5-fluoro-6-methoxy-benzothiazol-2-yl)-2H-pyrazol-3-ylamine
Show/Hide
|
C16H11ClFN5OS
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0572566
|
US8754233, 2-(5-Amino-4-benzothiazol-2-yl-2H-pyrazol-3-ylamino)-cyclopentanol
Show/Hide
|
C15H17N5OS
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0867463
|
4-(5-Amino-4-benzothiazol-2-yl-2H-pyrazol-3-ylamino)-N-thiazol-2-yl-benzenesulfonamide
Show/Hide
|
C19H15N7S3
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0524255
|
US8754233, 4-(5-Methoxy-benzothiazol-2-yl)-5-methyl-2H-pyrazol-3-ylamine
Show/Hide
|
C12H12N4OS
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
|
CP0524263
|
US8754233, [2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazol-5-yl]-methanol
Show/Hide
|
C12H12N4OS
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
|
CP0544775
|
US8754233, 4-Benzothiazol-2-yl-5-pyrrolidin-1-yl-1H-pyrazol-3-ylamine
Show/Hide
|
C14H15N5S
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
|
CP0549339
|
US8754233, 4-(5-Fluoro-6-methoxy-benzothiazol-2-yl)-5-(2-fluoro-phenyl)-2H-pyrazol-3-ylamine
Show/Hide
|
C17H12F2N4OS
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0566660
|
US8754233, 4-Benzothiazol-2-yl-5-(4-nitro-phenyl)-2H-pyrazol-3-ylamine
Show/Hide
|
C16H11N5O2S
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0462721
|
US8754233, 4-(5-Amino-4-benzothiazol-2-yl-1H-pyrazol-3-ylamino)-butyric acid
Show/Hide
|
C14H15N5O2S
|
1
|
| 1 |
IC50 = 4300 nM
|
|
|
|
CP0538909
|
US8754233, 2-(4-Benzothiazol-2-yl-1H-pyrazol-3-yl)-phenol
Show/Hide
|
C16H11N3OS
|
1
|
| 1 |
IC50 = 4600 nM
|
|
|
|
CP0538616
|
US8754233, 2-(5-Amino-3-methyl-1H-pyrazol-4-yl)-benzothiazole-6-sulfonic acid 4-fluoro-benzylamide
Show/Hide
|
C18H16FN5O2S2
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0391641
|
US8754233, 5-Methyl-4-[6-(4-methyl-piperazine-1-sulfonyl)-benzothiazol-2-yl]-2H-pyrazol-3-ylamine
Show/Hide
|
C16H20N6O2S2
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0385571
|
US8754233, 5-Methyl-4-[6-(4-methyl-piperazin-1-ylmethyl)-benzothiazol-2-yl]-2H-pyrazol-3-ylamine
Show/Hide
|
C17H22N6S
|
1
|
| 1 |
IC50 = 5000 nM
|
|
|
|
CP0566367
|
US8754233, N3-(4-Amino-phenyl)-4-benzothiazol-2-yl-1H-pyrazole-3,5-diamine
Show/Hide
|
C16H14N6S
|
1
|
| 1 |
IC50 = 5000 nM
|
|
|
