| Compound ID |
Compound Name |
Compound Formula |
|
CP0113029
|
N-[(2,6-difluorophenyl)methyl]-3-[(4-propyl-5-pyrimidin-4-yl-1,2,4-triazol-3-yl)methylamino]benzamide
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|
C24H23F2N7O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0112012
|
4-[4-fluoro-3-[(2-methoxyphenyl)methylcarbamoyl]phenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
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|
C28H25FN6O4
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0111456
|
4-[3-[(2,6-dimethylphenyl)methylcarbamoyl]-4-fluorophenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
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|
C29H27FN6O3
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0061504
|
4-[3-[(2,6-dimethoxyphenyl)methylcarbamoyl]-4-fluorophenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
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|
C29H27FN6O5
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0279940
|
4-[3-[(2,6-dichlorophenyl)methylcarbamoyl]-4-fluorophenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
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|
C27H21Cl2FN6O3
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0054841
|
4-[4-fluoro-3-(pyridin-2-ylmethylcarbamoyl)phenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C26H22FN7O3
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0061404
|
4-[4-fluoro-3-[(3-fluorophenyl)methylcarbamoyl]phenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C27H22F2N6O3
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0279933
|
4-[3-[(2,6-difluorophenyl)methylcarbamoyl]-4-fluorophenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C27H21F3N6O3
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0061490
|
4-[3-[2-(2,6-dimethylphenyl)ethylcarbamoyl]-4-fluorophenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C30H29FN6O3
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0174820
|
4-[4-fluoro-3-(isoquinolin-1-ylmethylcarbamoyl)phenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C30H24FN7O3
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0257052
|
4-[4-fluoro-3-(2-pyridin-2-ylethylcarbamoyl)phenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C27H24FN7O3
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0214468
|
4-[4-fluoro-3-[(3-methoxyphenyl)methylcarbamoyl]phenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C28H25FN6O4
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0061500
|
4-[3-[2-[(2,6-dimethoxyphenyl)methylamino]-2-oxoethyl]-4-fluorophenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C30H29FN6O5
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0191979
|
4-[4-fluoro-3-[(4-methoxyphenyl)methylcarbamoyl]phenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C28H25FN6O4
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0112011
|
4-[3-(benzylcarbamoyl)-4-fluorophenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C27H23FN6O3
|
1
|
| 1 |
IC50 = 690 nM
|
|
|
|
CP0025658
|
GSK-180736A
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|
C19H16FN5O2
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0075077
|
4-[3-[[2,6-bis(trifluoromethyl)phenyl]methylcarbamoyl]-4-fluorophenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C29H21F7N6O3
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0046806
|
(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine
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|
C19H20FNO3
|
1
|
| 1 |
IC50 = 1380 nM
|
|
|
|
CP0090326
|
4-[4-fluoro-3-[(3-methylpyridin-2-yl)methylcarbamoyl]phenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C27H24FN7O3
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0182293
|
4-[3-[[3,5-bis(trifluoromethyl)phenyl]methylcarbamoyl]-4-fluorophenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C29H21F7N6O3
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0455945
|
4-[4-fluoro-3-(methylcarbamoyl)phenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C21H19FN6O3
|
1
|
| 1 |
IC50 = 4300 nM
|
|
|
|
CP0054840
|
4-[3-[(2,6-dimethylphenyl)methylcarbamoyl]-4-fluorophenyl]-N-(1H-indazol-5-yl)-N,6-dimethyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C30H29FN6O3
|
1
|
| 1 |
IC50 = 4600 nM
|
|
|
|
CP0174819
|
4-[4-fluoro-3-(2-pyridin-4-ylethylcarbamoyl)phenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C27H24FN7O3
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0279937
|
2-fluoro-5-[5-(1H-indazol-5-ylcarbamoyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidin-4-yl]benzoic acid
Show/Hide
|
C20H16FN5O4
|
1
|
| 1 |
IC50 = 20000 nM
|
|
|
|
CP0279934
|
4-[3-[2-[(2,6-dimethylphenyl)methylamino]-2-oxoethyl]-4-fluorophenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C30H29FN6O3
|
1
|
| 1 |
IC50 = 25000 nM
|
|
|
|
CP0061497
|
4-[3-[2-[[2,6-bis(trifluoromethyl)phenyl]methylamino]-2-oxoethyl]-4-fluorophenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C30H23F7N6O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0113033
|
N-(1,3-benzodioxol-5-yl)-4-[4-fluoro-3-(pyridin-2-ylmethylcarbamoyl)phenyl]-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
Show/Hide
|
C26H22FN5O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
