Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[4-fluoro-3-[(3-methylpyridin-2-yl)methylcarbamoyl]phenyl]-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide
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 PubChem ID
CID: 118888918
Canonical SMILES
CC1=C(C(NC(=O)N1)c1ccc(F)c(c1)C(=O)NCc1ncccc1C)C(=O)Nc1ccc2[nH]ncc2c1
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Compound Formula C27H24FN7O3
Compound Structure
Protein Name
 Protein Info 
Beta-adrenergic receptor kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase GRK family
>
AGC protein kinase BARK subfamily
Uniprot ID
P25098
Gene Name
GRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4
 Cell Line Info 
Trichoplusia ni (Cabbage looper)  1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS