Brief Information of the Cell Line and Protein
Cell Line ID: CL000017 , HeLa
 Cell Line Info 
Synonyms
HELA
Hela
He La
He-La
HeLa-CCL2
Henrietta Lacks cells
Helacyton gartleri
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0030
Protein ID: PT03382 , Lysine-specific demethylase 5B
 Protein Info 
Gene Name KDM5B
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID Q9UGL1
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000017
 Cell Line Info 
 Protein ID: PT03382
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0138214
 Compound Info 
8-[4-[2-[4-[3-[2-(dimethylamino)ethyl]phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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C27H33N7O
  1
1
EC50 = 3770 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0138240
 Compound Info 
8-[4-(2-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylethyl)pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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C25H26N6O
  1
1
EC50 = 13400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0236794
 Compound Info 
8-[4-[2-[4-(3-chlorophenyl)-4-methylpiperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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C24H25ClN6O
  1
1
EC50 = 20800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0061173
 Compound Info 
8-[4-[2-[4-(3-chlorophenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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C23H23ClN6O
  1
1
EC50 = 24200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0236796
 Compound Info 
8-[4-[2-[4-(3-pyridin-3-ylphenyl)piperidin-1-yl]ethyl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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C28H27N7O
  1
1
EC50 = 26000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0138238
 Compound Info 
8-[4-[1-(cyclobutylmethyl)piperidin-4-yl]pyrazol-1-yl]-3H-pyrido[3,4-d]pyrimidin-4-one
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C20H24N6O
  1
1
EC50 = 26400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS