Brief Information of the Cell Line and Protein
Cell Line ID: CL000017 , HeLa
Synonyms
HELA
Hela
He La
He-La
HeLa-CCL2
Henrietta Lacks cells
Helacyton gartleri
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0030
Protein ID: PT01887 , Oxysterols receptor LXR-beta
Gene Name NR1H2
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P55055
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000017  Protein ID: PT01887
 
Compound ID Compound Name Compound Formula
CP0000804
2-[2-[2-(2,6-dichlorophenyl)propan-2-yl]-1-[2-fluoro-4-[3-fluoro-4-(hydroxymethyl)-5-methylsulfonylphenyl]phenyl]imidazol-4-yl]propan-2-ol
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C29H28Cl2F2N2O4S
 1
1
EC50 = 0.6 nM
   TI
   LI
   LO
   TS
CP0000797
2-[2-[2-(2-chloro-6-fluorophenyl)propan-2-yl]-1-[2-fluoro-4-[3-fluoro-4-(hydroxymethyl)-5-methylsulfonylphenyl]phenyl]imidazol-4-yl]propan-2-ol
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C29H28ClF3N2O4S
 1
1
EC50 = 1 nM
   TI
   LI
   LO
   TS
CP0005862
2-[1-[2-chloro-4-[3-fluoro-4-(hydroxymethyl)-5-methylsulfonylphenyl]phenyl]-2-[2-(2,6-dichlorophenyl)propan-2-yl]imidazol-4-yl]propan-2-ol
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C29H28Cl3FN2O4S
 1
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
CP0007677
2-[2-[1-(2,6-dichlorophenyl)ethyl]-1-[2-fluoro-4-[3-fluoro-4-(hydroxymethyl)-5-methylsulfonylphenyl]phenyl]imidazol-4-yl]propan-2-ol
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C28H26Cl2F2N2O4S
 1
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
CP0011843
2-[2-[2-(2-chlorophenyl)propan-2-yl]-1-[2-fluoro-4-[3-fluoro-4-(hydroxymethyl)-5-methylsulfonylphenyl]phenyl]imidazol-4-yl]propan-2-ol
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C29H29ClF2N2O4S
 1
1
EC50 = 2 nM
   TI
   LI
   LO
   TS
CP0000796
2-[2-[2-(2,6-dichlorophenyl)propan-2-yl]-1-[4-[3-fluoro-4-(hydroxymethyl)-5-methylsulfonylphenyl]phenyl]imidazol-4-yl]propan-2-ol
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C29H29Cl2FN2O4S
 1
1
EC50 = 3 nM
   TI
   LI
   LO
   TS
CP0000798
2-[2-[(2,6-dichlorophenyl)methyl]-1-[4-[3-fluoro-4-(hydroxymethyl)-5-methylsulfonylphenyl]phenyl]imidazol-4-yl]propan-2-ol
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C27H25Cl2FN2O4S
 1
1
EC50 = 5 nM
   TI
   LI
   LO
   TS
CP0005861
2-[2-[2-(2-chloro-3-fluorophenyl)propan-2-yl]-1-[4-[3-fluoro-4-(hydroxymethyl)-5-methylsulfonylphenyl]phenyl]imidazol-4-yl]propan-2-ol
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C29H29ClF2N2O4S
 1
1
EC50 = 8 nM
   TI
   LI
   LO
   TS
CP0009772
2-[2-[2-(2-chlorophenyl)propan-2-yl]-1-[4-[3-fluoro-4-(hydroxymethyl)-5-methylsulfonylphenyl]phenyl]imidazol-4-yl]propan-2-ol
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C29H30ClFN2O4S
 1
1
EC50 = 8 nM
   TI
   LI
   LO
   TS
CP0004250
2-[2-[(2-chlorophenyl)methyl]-1-[4-[4-(hydroxymethyl)-3-methylsulfonylphenyl]phenyl]imidazol-4-yl]propan-2-ol
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C27H27ClN2O4S
 1
1
EC50 = 9 nM
   TI
   LI
   LO
   TS
CP0006152
2-[2-[2-(2-chlorophenyl)propan-2-yl]-1-[4-[4-(hydroxymethyl)-3-methylsulfonylphenyl]phenyl]imidazol-4-yl]propan-2-ol
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C29H31ClN2O4S
 1
1
EC50 = 12 nM
   TI
   LI
   LO
   TS
CP0011842
2-[1-[4-[3-fluoro-4-(hydroxymethyl)-5-methylsulfonylphenyl]phenyl]-2-[2-(2-fluorophenyl)propan-2-yl]imidazol-4-yl]propan-2-ol
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C29H30F2N2O4S
 1
1
EC50 = 12 nM
   TI
   LI
   LO
   TS
CP0007847
2-[2-[2-(2,6-dichlorophenyl)propan-2-yl]-1-[4-(3-methylsulfonylphenyl)phenyl]imidazol-4-yl]propan-2-ol
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C28H28Cl2N2O3S
 1
1
EC50 = 18 nM
   TI
   LI
   LO
   TS
CP0000235
2-[2-[2-(2-chlorophenyl)propan-2-yl]-1-[4-[4-(1-hydroxyethyl)-3-methylsulfonylphenyl]phenyl]imidazol-4-yl]propan-2-ol
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C30H33ClN2O4S
 1
1
EC50 = 21 nM
   TI
   LI
   LO
   TS
CP0002051
2-[2-[2-(2-chlorophenyl)propan-2-yl]-1-[4-(3-methylsulfonylphenyl)phenyl]imidazol-4-yl]propan-2-ol
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C28H29ClN2O3S
 1
1
EC50 = 33 nM
   TI
   LI
   LO
   TS