Brief Information of the Compound and Protein
Compound Name
2-[2-[2-(2-chlorophenyl)propan-2-yl]-1-[4-[4-(1-hydroxyethyl)-3-methylsulfonylphenyl]phenyl]imidazol-4-yl]propan-2-ol
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PubChem ID
CID: 134150059
Canonical SMILES
CC(O)c1ccc(cc1S(C)(=O)=O)-c1ccc(cc1)-n1cc(nc1C(C)(C)c1ccccc1Cl)C(C)(C)O
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Compound Formula C30H33ClN2O4S
Compound Structure
Protein Name
Oxysterols receptor LXR-beta
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
P55055
Gene Name
NR1H2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  1
1
EC50 = 220 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 21 nM
   TI
   LI
   LO
   TS