| Compound ID |
Compound Name |
Compound Formula |
|
CP0577408
|
2-[6-[3-(1-methylcyclopropyl)phenyl]-3-azabicyclo[4.1.0]heptane-3-carbonyl]-7-oxa-5-azaspiro[3.4]octan-6-one
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|
C23H28N2O3
|
1
|
| 1 |
IC50 = 0.024 nM
|
|
|
|
CP0552671
|
(2s,4S)-N-((1s,3S)-3-(4-Isopropylphenyl)cyclobutyl)-N-methyl-6-oxo-7-oxa-5-
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|
C21H28N2O3
|
1
|
| 1 |
IC50 = 0.04 nM
|
|
|
|
CP0573585
|
(2s,4S)-N-((1s,3S)-3-(4-(tert-Butyl)phenyl)cyclobutyl)-N-methyl-6-oxo-7-oxa-5-
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|
C22H30N2O3
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0498474
|
(2s,4S)-N-((1s,3S)-3-(4-Cyclopropyl-3-methylphenyl)cyclobutyl)-N-methyl-6-oxo-
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|
C22H28N2O3
|
1
|
| 1 |
IC50 = 0.25 nM
|
|
|
|
CP0575259
|
(2s,4S)-N-Methyl-N-((1s,3S)-3-(4-(1-methylcyclopropyl)phenyl)cyclobutyl)-
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|
C22H28N2O3
|
1
|
| 1 |
IC50 = 0.25 nM
|
|
|
|
CP0547727
|
2-[1-(4-cyclopropyl-2-methylphenyl)-3-azabicyclo[3.1.0]hexane-3-carbonyl]-7-oxa-5-azaspiro[3.4]octan-6-one
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|
C22H26N2O3
|
1
|
| 1 |
IC50 = 0.35 nM
|
|
|
|
CP0545552
|
(2s,4S)-N-((1s,3S)-3-(3-(tert-Butyl)-4-fluorophenyl)cyclobutyl)-N-methyl-6-oxo-
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|
C22H29FN2O3
|
1
|
| 1 |
IC50 = 0.39 nM
|
|
|
|
CP0547731
|
(2s,4S)-N-((1s,3S)-3-(3-Cyclopropyl-5-methylphenyl)cyclobutyl)-N-methyl-6-oxo-
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|
C22H28N2O3
|
1
|
| 1 |
IC50 = 0.52 nM
|
|
|
|
CP0579017
|
2-[(1R,5S)-6-(4-tert-butylphenyl)-3-azabicyclo[3.1.0]hexane-3-carbonyl]-7-oxa-5-azaspiro[3.4]octan-6-one
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|
C22H28N2O3
|
1
|
| 1 |
IC50 = 0.69 nM
|
|
|
|
CP0578196
|
2-[(1R,5S)-6-(3-tert-butyl-5-deuteriophenyl)-3-azabicyclo[3.1.0]hexane-3-carbonyl]-7-oxa-5-azaspiro[3.4]octan-6-one
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|
C22H28N2O3
|
1
|
| 1 |
IC50 = 0.93 nM
|
|
|
|
CP0579015
|
2-[1-(4-tert-butylphenyl)-3-azabicyclo[3.1.0]hexane-3-carbonyl]-7-oxa-5-azaspiro[3.4]octan-6-one
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|
C22H28N2O3
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0500153
|
CHEMBL5092906
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|
C20H21F3N2O3
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0577407
|
2-[1-(3-tert-butylphenyl)-3-azabicyclo[3.1.0]hexane-3-carbonyl]-7-oxa-5-azaspiro[3.4]octan-6-one
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|
C22H28N2O3
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0570411
|
2-[(1R,5S)-6-(2,3-dihydro-1H-inden-5-yl)-3-azabicyclo[3.1.0]hexane-3-carbonyl]-7-oxa-5-azaspiro[3.4]octan-6-one
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|
C21H24N2O3
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0578195
|
2-[1-(4-methylphenyl)-3-azabicyclo[3.1.0]hexane-3-carbonyl]-7-oxa-5-azaspiro[3.4]octan-6-one
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|
C19H22N2O3
|
1
|
| 1 |
IC50 = 5.9 nM
|
|
|
|
CP0579016
|
2-[6-(2-methylphenyl)-3-azabicyclo[4.1.0]heptane-3-carbonyl]-7-oxa-5-azaspiro[3.4]octan-6-one
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|
C20H24N2O3
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0554158
|
2-(7,7-difluoro-6-phenyl-3-azabicyclo[4.1.0]heptane-3-carbonyl)-7-oxa-5-azaspiro[3.4]octan-6-one
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|
C19H20F2N2O3
|
1
|
| 1 |
IC50 = 203 nM
|
|
|
