Brief Information of the Cell Line and Protein
Cell Line ID: CL000017 , HeLa
Synonyms
HELA
Hela
He La
He-La
HeLa-CCL2
Henrietta Lacks cells
Helacyton gartleri
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0030
Protein ID: PT01223 , Aurora kinase B
Gene Name AURKB
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID Q96GD4
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000017  Protein ID: PT01223
 
Compound ID Compound Name Compound Formula
CP0015614
N-[4-[3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl]oxyphenyl]-4-phenylphthalazin-1-amine
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C30H23N7O
 1
1
EC50 = 15 nM
   TI
   LI
   LO
   TS
CP0026409
2-anilino-N-[4-[3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl]oxyphenyl]benzamide
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C29H24N6O2
 1
1
EC50 = 15 nM
   TI
   LI
   LO
   TS
CP0501598
5-Fluoro-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)-2-(phenylamino)benzamide
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C29H23FN6O2
 1
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
CP0025073
4-(4-Fluorophenyl)-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)-pyridin-2-yloxy)phenyl)phthalazin-1-amine
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C30H22FN7O
 1
1
EC50 = 24 nM
   TI
   LI
   LO
   TS
CP0471603
2-(4-Fluorophenylamino)-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)benzamide
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C29H23FN6O2
 1
1
EC50 = 28 nM
   TI
   LI
   LO
   TS
CP0026408
2-anilino-N-[3-methyl-4-[3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl]oxyphenyl]benzamide
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C30H26N6O2
 1
1
EC50 = 89 nM
   TI
   LI
   LO
   TS
CP0020460
2-anilino-N-[2-methyl-4-[3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl]oxyphenyl]benzamide
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C30H26N6O2
 1
1
EC50 = 1450 nM
   TI
   LI
   LO
   TS
CP0016235
N-[3-methyl-4-[3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl]oxyphenyl]-2-phenoxybenzamide
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C30H25N5O3
 1
1
EC50 > 1200 nM
   TI
   LI
   LO
   TS
CP0019760
3-Chloro-N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)-pyridin-2-yloxy)phenyl)benzamide
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C24H20ClN5O2
 1
1
EC50 > 1200 nM
   TI
   LI
   LO
   TS
CP0020487
N-[3-methyl-4-[3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl]oxyphenyl]-3-phenoxybenzamide
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C30H25N5O3
 1
1
EC50 > 1200 nM
   TI
   LI
   LO
   TS
CP0023880
N-[3-methyl-4-[3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl]oxyphenyl]-3-(trifluoromethyl)benzamide
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C25H20F3N5O2
 1
1
EC50 > 1200 nM
   TI
   LI
   LO
   TS
CP0026752
4-Chloro-N-(3-methyl-4-(3-(2-(methylamino)pyrimidin-4-yl)-pyridin-2-yloxy)phenyl)benzamide
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C24H20ClN5O2
 1
1
EC50 > 1200 nM
   TI
   LI
   LO
   TS
CP0204584
4-[[6-chloro-2-(1,3-dimethylpyrazol-4-yl)-1H-imidazo[4,5-b]pyridin-7-yl]oxy]-N-pyridin-3-ylbenzamide
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C23H18ClN7O2
 1
1
IC50 = 19720 nM
   TI
   LI
   LO
   TS
CP0296123
4-[[6-chloro-2-(1,3-dimethylpyrazol-4-yl)-1H-imidazo[4,5-b]pyridin-7-yl]oxy]-N-pyridin-4-ylbenzamide
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C23H18ClN7O2
 1
1
IC50 = 19740 nM
   TI
   LI
   LO
   TS
CP0075920
4-[[6-chloro-2-(1,3-dimethylpyrazol-4-yl)-1H-imidazo[4,5-b]pyridin-7-yl]oxy]-N-cyclobutylbenzamide
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C22H21ClN6O2
 1
1
IC50 = 24240 nM
   TI
   LI
   LO
   TS
CP0270630
4-[[6-chloro-2-(1,3-dimethylpyrazol-4-yl)-1H-imidazo[4,5-b]pyridin-7-yl]oxy]-N-phenylbenzamide
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C24H19ClN6O2
 1
1
IC50 = 76840 nM
   TI
   LI
   LO
   TS