| Compound ID |
Compound Name |
Compound Formula |
|
CP0499748
|
3-((4-(1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl)phenoxy)methyl)isoquinoline
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|
C25H20N4O
|
1
|
| 1 |
IC50 = 0.18 nM
|
|
|
|
CP0511619
|
2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-3-pyridin-3-yl-propionic acid
Show/Hide
|
C32H25FN4O3
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0488856
|
US9193736, 164
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|
C30H27N5O3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0441482
|
1-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-cyclopropanecarboxylic acid
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|
C28H22FN3O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0462875
|
US9193736, 41
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|
C28H25N5O3
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0189627
|
US9193736, 40
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|
C28H23N5O3
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0382142
|
2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-4,4,4-trifluoro-butyric acid
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|
C28H21F4N3O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0511616
|
(R)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-quinolin-4-ylamino]-propionic acid
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|
C27H23N3O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0511617
|
(S)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-3-phenyl-propionic acid
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|
C33H26FN3O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0528121
|
3-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C27H22FN3O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0462874
|
US9193736, 28
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|
C28H23N7O4S
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0399495
|
US9193736, 36
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|
C29H26N6O4S
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0430090
|
US9193736, 169
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|
C32H31N5O3
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0394269
|
2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-3-phenyl-propionic acid
Show/Hide
|
C33H26FN3O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0501663
|
4-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-butyric acid
Show/Hide
|
C28H24FN3O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0516366
|
(R)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-methoxy-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C28H25N3O4
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0402553
|
US9193736, 12
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|
C30H28N8O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0518913
|
US9193736, 168
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|
C35H36N6O3
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0506701
|
US9193736, 102
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|
C29H23N7O3
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0170595
|
(S)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C27H22FN3O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0441484
|
2-[[3-cyano-2-[4-(2-ethoxyphenyl)phenyl]-6-fluoroquinolin-4-yl]-methylamino]acetic acid
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|
C27H22FN3O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0511615
|
4-[3-cyano-2-(2'-ethoxy-3-fluoro-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-butyric acid
Show/Hide
|
C28H23F2N3O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0412139
|
US9193736, 100
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|
C33H32N6O3
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0382143
|
2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-butyric acid
Show/Hide
|
C28H24FN3O3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0431786
|
US9085584, 5
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|
C18H14FN5O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0278606
|
(R)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C27H22FN3O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0501660
|
(R)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-7-methyl-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C28H25N3O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0501662
|
2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C27H22FN3O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0508142
|
3-[2-(5-methoxy-1-phenylbenzimidazol-2-yl)ethyl]-1-methylimidazo[4,5-b]pyridin-2-one
Show/Hide
|
C23H21N5O2
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
|
CP0449472
|
2-[[3-cyano-2-[4-(2-ethoxyphenyl)phenyl]-6-fluoroquinolin-4-yl]-ethylamino]acetic acid
Show/Hide
|
C28H24FN3O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0501278
|
2-[[3-cyano-2-[4-(2-ethoxyphenyl)phenyl]-6-fluoroquinolin-4-yl]amino]acetic acid
Show/Hide
|
C26H20FN3O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0537457
|
3-[2-(4-methoxy-1-phenylbenzimidazol-2-yl)ethyl]-1-methylimidazo[4,5-b]pyridin-2-one
Show/Hide
|
C23H21N5O2
|
1
|
| 1 |
IC50 = 7.3 nM
|
|
|
|
CP0423287
|
US9193736, 54
Show/Hide
|
C29H24N8O2
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0415066
|
US9085584, 8
Show/Hide
|
C18H16FN5O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0480535
|
3-methyl-1-[2-(5-methyl-1-phenylbenzimidazol-2-yl)ethyl]pyrazolo[3,4-b]pyridine
Show/Hide
|
C23H21N5
|
1
|
| 1 |
IC50 = 8.3 nM
|
|
|
|
CP0421037
|
US9193736, 65
Show/Hide
|
C30H24N6O4
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0513103
|
5-methyl-7-[2-(5-methyl-1-phenylbenzimidazol-2-yl)ethyl]imidazo[1,5-b]pyridazine
Show/Hide
|
C23H21N5
|
1
|
| 1 |
IC50 = 9.1 nM
|
|
|
|
CP0382479
|
1-methyl-3-[2-(5-methyl-1-phenylbenzimidazol-2-yl)ethyl]imidazo[4,5-b]pyridin-2-one
Show/Hide
|
C23H21N5O
|
1
|
| 1 |
IC50 = 9.2 nM
|
|
|
|
CP0116141
|
3-[2-(7-methoxy-3-phenylimidazo[4,5-b]pyridin-2-yl)ethyl]-1,7-dimethylimidazo[4,5-b]pyridin-2-one
Show/Hide
|
C23H22N6O2
|
1
|
| 1 |
IC50 = 9.5 nM
|
|
|
|
CP0485256
|
2-{[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-yl]-methyl-amino}-propionic acid
Show/Hide
|
C28H24FN3O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0546113
|
US9085584, 6
Show/Hide
|
C19H17N5O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0102239
|
5-((1H-benzo[d]imidazol-2-yl)methylthio)-2-methyl-[1,2,4]triazolo[1,5-c]quinazoline
Show/Hide
|
C18H14N6S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0559214
|
4-[8-morpholin-4-yl-2-(quinolin-2-ylsulfanylmethyl)imidazo[1,2-b]pyridazin-3-yl]piperazine-1-sulfonamide
Show/Hide
|
C24H28N8O3S2
|
1
|
| 1 |
IC50 = 13.8 nM
|
|
|
|
CP0459958
|
US9085584, 9
Show/Hide
|
C18H14ClN5O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0485255
|
1-[3-Cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-cyclopentanecarboxylic acid
Show/Hide
|
C30H26FN3O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0102238
|
2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C24H23N5
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0529130
|
9-Chloro-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C23H20ClN5
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0840244
|
2-({[1-(1,3-Thiazol-2-yl)-1H-benzimidazol-6-yl]oxy}methyl)quinoline
Show/Hide
|
C20H14N4OS
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0508734
|
US9085584, 7
Show/Hide
|
C19H19N5O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0083432
|
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoquinoline
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|
C20H21NO4
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0444732
|
4-[3-cyano-2-(2'-ethoxy-2-fluoro-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-butyric acid
Show/Hide
|
C28H23F2N3O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0501661
|
(R)-2-[6-chloro-3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C27H22ClN3O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0412220
|
2-[2-(2-Methoxyphenyl)-1H-benzimidazol-5-yl]-5,8-dimethyl[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C21H18N6O
|
1
|
| 1 |
IC50 = 19.5 nM
|
|
|
|
CP0425609
|
N-ethyl-4-methyl-1-pyridin-2-yl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Show/Hide
|
C18H16N6O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0481487
|
1-[[1-(2-chlorophenyl)-4-methyl-[1,2,4]triazolo[4,3-a]quinoxalin-8-yl]methyl]piperidin-4-ol
Show/Hide
|
C22H22ClN5O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0482195
|
1-(2-chlorophenyl)-4-methyl-N-(2-pyrrolidin-1-ylethyl)-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Show/Hide
|
C23H23ClN6O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0466704
|
US9193736, 6
Show/Hide
|
C29H30N8OS
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0510288
|
US9193736, 13
Show/Hide
|
C30H32N8O
|
1
|
| 1 |
IC50 = 20.4 nM
|
|
|
|
CP0490432
|
(R)-2-[7-chloro-3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C27H22ClN3O3
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0483836
|
US9193736, 177
Show/Hide
|
C30H30N8O
|
1
|
| 1 |
IC50 = 21.4 nM
|
|
|
|
CP0511618
|
(R)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-3-phenyl-propionic acid
Show/Hide
|
C33H26FN3O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0538100
|
US9085584, 107
Show/Hide
|
C22H20FN5O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0355003
|
2-[(6-methoxy-3-phenyl-2-propan-2-ylbenzimidazol-5-yl)oxymethyl]quinoline
Show/Hide
|
C27H25N3O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0366792
|
5,8-Dimethyl-2-(2-phenyl-1H-benzimidazol-5-yl)[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C20H16N6
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0382480
|
2-methyl-4-[2-(5-methyl-1-phenylbenzimidazol-2-yl)ethyl]pyrido[2,3-b]pyrazin-3-one
Show/Hide
|
C24H21N5O
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0513104
|
3-[2-(7-methoxy-3-phenylimidazo[4,5-b]pyridin-2-yl)ethyl]-1-methylimidazo[4,5-b]pyridin-2-one
Show/Hide
|
C22H20N6O2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0396021
|
5,8-dimethyl-2-(2-thiophen-2-yl-3H-benzimidazol-5-yl)-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C18H14N6S
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0425613
|
N-benzyl-1-(2-chlorophenyl)-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Show/Hide
|
C24H18ClN5O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0450415
|
1-(2-chlorophenyl)-N-ethyl-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Show/Hide
|
C19H16ClN5O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0450478
|
1-(2-chlorophenyl)-4-methyl-8-[(4-methylpiperazin-1-yl)methyl]-[1,2,4]triazolo[4,3-a]quinoxaline
Show/Hide
|
C22H23ClN6
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0432034
|
3-[2-(2'-trifluoromethyl-biphenyl-4-yl)-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C25H19F3N2O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0466781
|
8-Methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C24H23N5O
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0414199
|
4-[[1-(2-chlorophenyl)-4-methyl-[1,2,4]triazolo[4,3-a]quinoxalin-8-yl]methyl]morpholine
Show/Hide
|
C21H20ClN5O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0433377
|
N-benzyl-1-(2-chlorophenyl)-N,4-dimethyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Show/Hide
|
C25H20ClN5O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0435545
|
ethyl 1-(2-chlorophenyl)-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxylate
Show/Hide
|
C19H15ClN4O2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0477195
|
N-ethyl-1-(2-methoxypyridin-3-yl)-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Show/Hide
|
C19H18N6O2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0482191
|
1-(2-chlorophenyl)-4-methyl-N-(oxan-4-yl)-[1,2,4]triazolo[4,3-a]quinoxalin-8-amine
Show/Hide
|
C21H20ClN5O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0482330
|
N-ethyl-1-(2-methoxyphenyl)-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Show/Hide
|
C20H19N5O2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0413898
|
US9085584, 2
Show/Hide
|
C16H12ClN5O
|
2
|
| 1 |
IC50 = 33 nM
|
|
|
| 2 |
IC50 = 40 nM
|
|
|
|
CP0501275
|
4-[3-cyano-2-(2'-ethoxy-2-methyl-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-butyric acid
Show/Hide
|
C29H26FN3O3
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0452723
|
3-[2-(2'-ethyl-biphenyl-4-yl)-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C26H24N2O2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0511620
|
3-[2-(2'-ethoxy-biphenyl-4-yl)-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C26H24N2O3
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0248670
|
5,8-dimethyl-2-(2-phenylimidazo[1,2-a]pyrimidin-7-yl)-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C19H15N7
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0543849
|
7-Methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C24H23N5O
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0487712
|
3-[2-(5-methoxy-1-pyridin-3-ylbenzimidazol-2-yl)ethyl]-1-methylimidazo[4,5-b]pyridin-2-one
Show/Hide
|
C22H20N6O2
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0412219
|
US10138245, Example 2
Show/Hide
|
C20H15FN6
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0393394
|
4-[9-[[4-(2-chlorophenyl)phenyl]methyl]-8-methylpurin-6-yl]morpholine
Show/Hide
|
C23H22ClN5O
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0513391
|
2-[2-(3-methoxypyridin-2-yl)-3H-benzimidazol-5-yl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C20H17N7O
|
1
|
| 1 |
IC50 = 40 nM
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|
|
|
CP0381821
|
1-(2-chlorophenyl)-4-methyl-N-(2-phenylethyl)-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Show/Hide
|
C25H20ClN5O
|
1
|
| 1 |
IC50 = 41 nM
|
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|
|
CP0450414
|
N-ethyl-1-(2-fluorophenyl)-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-8-carboxamide
Show/Hide
|
C19H16FN5O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0481489
|
4-[[1-(2-chlorophenyl)-4-methyl-[1,2,4]triazolo[4,3-a]quinoxalin-8-yl]amino]cyclohexan-1-ol
Show/Hide
|
C22H22ClN5O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0375687
|
US9085584, 12
Show/Hide
|
C16H9ClF3N5O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0501664
|
3-[2-(2'-morpholin-4-ylmethyl-biphenyl-4-yl)-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C29H29N3O3
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0482326
|
5,7-Dimethyl-2-(2-phenyl-1H-benzo[d]imidazol-5-yl)-[1,2,4]triazolo-[1,5-a]pyrimidine
Show/Hide
|
C20H16N6
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0466777
|
2-Methyl-5-((1-methyl-4-phenyl-1H-imidazol-2-ylthio)-methyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C22H19N5S
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0179223
|
2-Methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)-ethyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C23H21N5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0529129
|
8-Chloro-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C23H20ClN5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0466780
|
7-Chloro-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C23H20ClN5
|
1
|
| 1 |
IC50 = 52 nM
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|
|
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CP0396025
|
2-[2-(2-methoxyphenyl)imidazo[1,2-a]pyrimidin-7-yl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C20H17N7O
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
|
CP0482328
|
2-[2-(4-FLuorophenyl)-1H-benzimidazol-5-yl]-5,8-dimethyl[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C20H15FN6
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0465807
|
4-[8-methyl-9-[[4-(2-methylpyridin-4-yl)phenyl]methyl]purin-6-yl]morpholine
Show/Hide
|
C23H24N6O
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0465808
|
4-[8-methyl-9-[[4-(1H-pyrazolo[3,4-b]pyridin-5-yl)phenyl]methyl]purin-6-yl]morpholine
Show/Hide
|
C23H22N8O
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0454490
|
4-[8-methyl-9-[(4-pyridin-3-ylphenyl)methyl]purin-6-yl]morpholine
Show/Hide
|
C22H22N6O
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0396692
|
4-[9-[[4-(4-methoxyphenyl)phenyl]methyl]-8-methylpurin-6-yl]morpholine
Show/Hide
|
C24H25N5O2
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0513387
|
5,8-Dimethyl-2-[2-(pyridin-2-yl)-1H-benzimidazol-5-yl][1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C19H15N7
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0555893
|
2-[2-(furan-2-yl)-3H-benzimidazol-5-yl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C18H14N6O
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0454483
|
4-[8-methyl-9-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]purin-6-yl]morpholine
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0865140
|
6-{5,8-Dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl}-2-(3-fluoropyridin-2-yl)-1H-1,3-benzodiazole
Show/Hide
|
C19H14FN7
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0244384
|
2-[(3-pyrimidin-4-ylbenzimidazol-5-yl)oxymethyl]quinoline
Show/Hide
|
C21H15N5O
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0408918
|
7-Chloro-2-methyl-5-((1-methyl-4-phenyl-1H-imidazol-2-ylthio)methyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C22H18ClN5S
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0476608
|
4-[9-[[4-(4-methylphenyl)phenyl]methyl]purin-6-yl]morpholine
Show/Hide
|
C23H23N5O
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0529128
|
2,9-Dimethyl-5-((1-methyl-4-phenyl-1H-imidazol-2-ylthio)methyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C23H21N5S
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0196092
|
4-[8-methyl-9-[(4-pyrimidin-5-ylphenyl)methyl]purin-6-yl]morpholine
Show/Hide
|
C21H21N7O
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0408075
|
2-[2-(4-fluorophenyl)imidazo[1,2-a]pyrimidin-7-yl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C19H14FN7
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0438211
|
US9085584, 91
Show/Hide
|
C22H22ClN5O
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0404560
|
2,7-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C24H23N5
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0441481
|
(R)-2-[3-cyano-2-(2'-ethoxy-3-fluoro-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C27H21F2N3O3
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0466778
|
7-Methoxy-2-methyl-5-((1-methyl-4-phenyl-1H-imidazol-2-ylthio)methyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C23H21N5OS
|
1
|
| 1 |
IC50 = 83 nM
|
|
|
|
CP0482327
|
5,8-Dimethyl-2-[2-(1,3-thiazol-2-yl)-1H-benz-imidazol-5-yl][1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C17H13N7S
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0760599
|
2-{[(3-Phenyl-3H-imidazo[4,5-b]pyridin-5-yl)oxy]methyl}quinoline
Show/Hide
|
C22H16N4O
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0367877
|
2-[(3-phenyl-2-propan-2-ylbenzimidazol-5-yl)oxymethyl]quinoline
Show/Hide
|
C26H23N3O
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0463517
|
7-[2-(5-methyl-1-phenylbenzimidazol-2-yl)ethyl]imidazo[1,5-b]pyridazine
Show/Hide
|
C22H19N5
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0412218
|
US10138245, Example 56
Show/Hide
|
C19H15N7
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
|
CP0557695
|
3-[2-(5-methoxy-1-pyridin-4-ylbenzimidazol-2-yl)ethyl]-1-methylimidazo[4,5-b]pyridin-2-one
Show/Hide
|
C22H20N6O2
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0054662
|
2-[(3-pyridin-4-ylbenzimidazol-5-yl)oxymethyl]quinoline
Show/Hide
|
C22H16N4O
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0501276
|
(R)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6,7-difluoro-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C27H21F2N3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0466779
|
8-Methoxy-2-methyl-5-((1-methyl-4-phenyl-1H-imidazol-2-ylthio)methyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C23H21N5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0454482
|
4-[9-[(4-phenylphenyl)methyl]purin-6-yl]morpholine
Show/Hide
|
C22H21N5O
|
1
|
| 1 |
IC50 = 103 nM
|
|
|
|
CP0513525
|
4-[9-(naphthalen-2-ylmethyl)purin-6-yl]morpholine
Show/Hide
|
C20H19N5O
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0408076
|
2-[2-(3-chlorophenyl)imidazo[1,2-a]pyrimidin-7-yl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C19H14ClN7
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0513081
|
9-Chloro-2-methyl-5-((1-methyl-4-phenyl-1H-imidazol-2-ylthio)methyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C22H18ClN5S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0480536
|
3-[2-(7-methoxy-3-phenylimidazo[4,5-b]pyridin-2-yl)ethyl]-1-methylimidazo[4,5-b]pyrazin-2-one
Show/Hide
|
C21H19N7O2
|
1
|
| 1 |
IC50 = 111 nM
|
|
|
|
CP0479709
|
4-[8-methyl-9-[(4-phenylphenyl)methyl]purin-6-yl]morpholine
Show/Hide
|
C23H23N5O
|
1
|
| 1 |
IC50 = 113 nM
|
|
|
|
CP0865138
|
2-(7-{5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl}imidazo[1,2-a]pyrimidin-2-yl)pyridine
Show/Hide
|
C18H14N8
|
1
|
| 1 |
IC50 = 115 nM
|
|
|
|
CP0508283
|
4-[8-methyl-9-[(4-pyridin-4-ylphenyl)methyl]purin-6-yl]morpholine
Show/Hide
|
C22H22N6O
|
1
|
| 1 |
IC50 = 116 nM
|
|
|
|
CP0482329
|
2-[6-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-1H-benzimidazol-2-yl]-4-methyl-1,3-thiazole
Show/Hide
|
C18H15N7S
|
1
|
| 1 |
IC50 = 117 nM
|
|
|
|
CP0471123
|
4-[9-[[4-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methyl]-8-methylpurin-6-yl]morpholine
Show/Hide
|
C22H24N6O2
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
|
CP0382144
|
2-(N-[3-cyano-2-[4-(2-ethoxyphenyl)phenyl]-6-fluoroquinolin-4-yl]anilino)acetic acid
Show/Hide
|
C32H24FN3O3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0485260
|
4-[3-cyano-2-(2'-ethoxy-3-methyl-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-butyric acid
Show/Hide
|
C29H26FN3O3
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0402817
|
US9085584, 11
Show/Hide
|
C16H12ClN5O
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0577491
|
4-[3-(6-piperazin-1-ylpyridin-3-yl)-2-(quinolin-2-ylmethyl)imidazo[1,2-b]pyridazin-8-yl]morpholine
Show/Hide
|
C29H30N8O
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0505189
|
8-Chloro-2-methyl-5-((1-methyl-4-phenyl-1H-imidazol-2-ylthio)methyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C22H18ClN5S
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0454491
|
4-[(8-methyl-6-morpholin-4-ylpurin-9-yl)methyl]-N-phenylbenzamide
Show/Hide
|
C24H24N6O2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0396022
|
5-[6-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-1H-benzimidazol-2-yl]-1,3-thiazole
Show/Hide
|
C17H13N7S
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0905292
|
2-(7-{5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl}imidazo[1,2-a]pyrimidin-2-yl)-1,3-thiazole
Show/Hide
|
C16H12N8S
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0458494
|
3-[2-(4'-methyl-biphenyl-4-yl)-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C25H22N2O2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0862252
|
2-(2-Bromophenyl)-7-{5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl}imidazo[1,2-a]pyrimidine
Show/Hide
|
C19H14BrN7
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0408074
|
2-[2-(3-bromophenyl)-3H-benzimidazol-5-yl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C20H15BrN6
|
1
|
| 1 |
IC50 = 146 nM
|
|
|
|
CP0054661
|
N,N-dimethyl-1-phenyl-6-(quinolin-2-ylmethoxy)benzimidazol-2-amine
Show/Hide
|
C25H22N4O
|
1
|
| 1 |
IC50 = 152 nM
|
|
|
|
CP0516364
|
(R)-2-[3-cyano-2-(2'-ethoxy-2-fluoro-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C27H21F2N3O3
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0407960
|
2,7-Dimethyl-5-((1-methyl-4-phenyl-1H-imidazol-2-ylthio)methyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C23H21N5S
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0389045
|
2-[2-(5-chlorothiophen-2-yl)-3H-benzimidazol-5-yl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C18H13ClN6S
|
1
|
| 1 |
IC50 = 161 nM
|
|
|
|
CP0572487
|
4-methyl-2-(2-phenylimidazo[1,2-a]pyrimidin-7-yl)quinazoline
Show/Hide
|
C21H15N5
|
1
|
| 1 |
IC50 = 163 nM
|
|
|
|
CP0244385
|
2-[[2-(methoxymethyl)-3-phenylbenzimidazol-5-yl]oxymethyl]quinoline
Show/Hide
|
C25H21N3O2
|
1
|
| 1 |
IC50 = 166 nM
|
|
|
|
CP0389044
|
5,8-dimethyl-2-(2-pyridin-3-yl-3H-benzimidazol-5-yl)-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C19H15N7
|
1
|
| 1 |
IC50 = 166 nM
|
|
|
|
CP0390081
|
4-[9-[[4-(4-chlorophenyl)phenyl]methyl]-8-methylpurin-6-yl]morpholine
Show/Hide
|
C23H22ClN5O
|
1
|
| 1 |
IC50 = 168 nM
|
|
|
|
CP0548152
|
4-[8-ethyl-9-[(4-phenylphenyl)methyl]purin-6-yl]morpholine
Show/Hide
|
C24H25N5O
|
1
|
| 1 |
IC50 = 168 nM
|
|
|
|
CP0425030
|
US9085584, 12a
Show/Hide
|
C17H12F3N5O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0392097
|
2-[2-(3-Fluorophenyl)-1H-benzimidazol-5-yl]-5,8-dimethyl[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C20H15FN6
|
1
|
| 1 |
IC50 = 172 nM
|
|
|
|
CP0318540
|
2-[(2-cyclopropyl-3-phenylbenzimidazol-5-yl)oxymethyl]quinoline
Show/Hide
|
C26H21N3O
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0487183
|
US9085584, 89
Show/Hide
|
C20H18ClN5O
|
1
|
| 1 |
IC50 = 187 nM
|
|
|
|
CP0412213
|
2-[6-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-1H-benzimidazol-2-yl]-5-methyl-1,3-thiazole
Show/Hide
|
C18H15N7S
|
1
|
| 1 |
IC50 = 198 nM
|
|
|
|
CP0411447
|
1-methyl-3-[2-(6-methyl-3-phenylimidazo[4,5-b]pyridin-2-yl)ethyl]imidazo[4,5-b]pyridin-2-one
Show/Hide
|
C22H20N6O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0529578
|
2-[(2-ethyl-3-phenylbenzimidazol-5-yl)oxymethyl]quinoline
Show/Hide
|
C25H21N3O
|
1
|
| 1 |
IC50 = 208 nM
|
|
|
|
CP0513102
|
8-methyl-6-[2-(5-methyl-1-phenylbenzimidazol-2-yl)ethyl]imidazo[1,5-a]pyrimidine
Show/Hide
|
C23H21N5
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0222632
|
2-[(6-methoxy-3-phenylbenzimidazol-5-yl)oxymethyl]quinoline
Show/Hide
|
C24H19N3O2
|
1
|
| 1 |
IC50 = 214 nM
|
|
|
|
CP0508143
|
3-[2-(5-methoxy-1-pyridin-2-ylbenzimidazol-2-yl)ethyl]-1-methylimidazo[4,5-b]pyridin-2-one
Show/Hide
|
C22H20N6O2
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0389042
|
5,8-dimethyl-2-[2-(2-methylphenyl)-3H-benzimidazol-5-yl]-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C21H18N6
|
1
|
| 1 |
IC50 = 242 nM
|
|
|
|
CP0455326
|
N-[2-(2-bromo-4-methoxyphenyl)ethyl]-2-methyl-8-morpholin-4-ylimidazo[1,2-a]pyrazin-3-amine
Show/Hide
|
C20H24BrN5O2
|
1
|
| 1 |
IC50 = 243 nM
|
|
|
|
CP0414101
|
US9085584, 10
Show/Hide
|
C16H13N5O
|
1
|
| 1 |
IC50 = 254 nM
|
|
|
|
CP0409883
|
US9085584, 4
Show/Hide
|
C15H10FN5O
|
2
|
| 1 |
IC50 = 256 nM
|
|
|
| 2 |
IC50 = 441 nM
|
|
|
|
CP0508282
|
4-[9-[[4-(3-chlorophenyl)phenyl]methyl]-8-methylpurin-6-yl]morpholine
Show/Hide
|
C23H22ClN5O
|
1
|
| 1 |
IC50 = 258 nM
|
|
|
|
CP0476921
|
4-[6-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-1H-benzimidazol-2-yl]-1,3-thiazole
Show/Hide
|
C17H13N7S
|
1
|
| 1 |
IC50 = 268 nM
|
|
|
|
CP0530706
|
5,8-dimethyl-2-(2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C19H15N7
|
1
|
| 1 |
IC50 = 268 nM
|
|
|
|
CP0476918
|
US10138245, Example 3
Show/Hide
|
C19H15N7
|
1
|
| 1 |
IC50 = 279 nM
|
|
|
|
CP0513385
|
5,8-dimethyl-2-[2-(1-methylimidazol-2-yl)-3H-benzimidazol-5-yl]-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C18H16N8
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0539804
|
5,8-dimethyl-2-[2-[2-(trifluoromethoxy)phenyl]-3H-benzimidazol-5-yl]-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C21H15F3N6O
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0569974
|
5,7-dimethyl-2-(2-pyridin-2-ylimidazo[1,2-a]pyrimidin-7-yl)-[1,2,4]triazolo[1,5-a]pyrimidine
Show/Hide
|
C18H14N8
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0374614
|
US9085584, 60
Show/Hide
|
C17H14ClN5O
|
1
|
| 1 |
IC50 = 285 nM
|
|
|
|
CP0318539
|
2-[(3-phenyl-2-propylbenzimidazol-5-yl)oxymethyl]quinoline
Show/Hide
|
C26H23N3O
|
1
|
| 1 |
IC50 = 299 nM
|
|
|
|
CP0385891
|
US9085584, 28
Show/Hide
|
C18H16ClN5O2
|
2
|
| 1 |
IC50 = 299 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0463186
|
US9085584, 88
Show/Hide
|
C22H20ClN5O
|
1
|
| 1 |
IC50 = 302 nM
|
|
|
|
CP0233932
|
2-[(2-methyl-3-phenylbenzimidazol-5-yl)oxymethyl]quinoline
Show/Hide
|
C24H19N3O
|
1
|
| 1 |
IC50 = 305 nM
|
|
|
|
CP0462986
|
US9085584, 79
Show/Hide
|
C22H25N5O
|
1
|
| 1 |
IC50 = 305 nM
|
|
|
|
CP0318541
|
2-[(3-phenylbenzimidazol-5-yl)oxymethyl]quinoline
Show/Hide
|
C23H17N3O
|
1
|
| 1 |
IC50 = 309 nM
|
|
|
|
CP0572485
|
4-methyl-2-(2-phenyl-3H-benzimidazol-5-yl)quinazoline
Show/Hide
|
C22H16N4
|
1
|
| 1 |
IC50 = 315 nM
|
|
|
|
CP0390078
|
4-[9-[(4-bromophenyl)methyl]-8-methylpurin-6-yl]morpholine
Show/Hide
|
C17H18BrN5O
|
1
|
| 1 |
IC50 = 327 nM
|
|
|
|
CP0390082
|
N-[2-(4-methoxy-2-phenylphenyl)ethyl]-2-methyl-8-morpholin-4-ylimidazo[1,2-a]pyrazin-3-amine
Show/Hide
|
C26H29N5O2
|
1
|
| 1 |
IC50 = 336 nM
|
|
|
|
CP0413529
|
US9085584, 1
Show/Hide
|
C15H10ClN5O
|
2
|
| 1 |
IC50 = 355 nM
|
|
|
| 2 |
IC50 = 421 nM
|
|
|
|
CP0572480
|
5,7-dimethyl-2-(2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-[1,2,4]triazolo[1,5-a]pyrimidine
Show/Hide
|
C19H15N7
|
1
|
| 1 |
IC50 = 381 nM
|
|
|
|
CP0446303
|
2-[6-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-1H-benzimidazol-2-yl]benzonitrile
Show/Hide
|
C21H15N7
|
1
|
| 1 |
IC50 = 382 nM
|
|
|
|
CP0396693
|
2-methyl-8-morpholin-4-yl-N-[(4-pyridin-4-ylphenyl)methyl]imidazo[1,2-a]pyrazin-3-amine
Show/Hide
|
C23H24N6O
|
1
|
| 1 |
IC50 = 391 nM
|
|
|
|
CP0432030
|
3-methyl-2-(4-propylphenyl)quinoline-4-carboxylic acid
Show/Hide
|
C20H19NO2
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0567377
|
US9085584, 3
Show/Hide
|
C16H13N5O
|
1
|
| 1 |
IC50 = 411 nM
|
|
|
|
CP0466782
|
9-Methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)pyrazolo[1,5-c]quinazoline
Show/Hide
|
C24H23N5O
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0454484
|
N-[2-(2,6-dichlorophenyl)ethyl]-2-methyl-8-morpholin-4-ylimidazo[1,2-a]pyrazin-3-amine
Show/Hide
|
C19H21Cl2N5O
|
1
|
| 1 |
IC50 = 447 nM
|
|
|
|
CP0074046
|
N-[[4-(3,4-dimethoxyphenyl)phenyl]methyl]-2-methyl-8-morpholin-4-ylimidazo[1,2-a]pyrazin-3-amine
Show/Hide
|
C26H29N5O3
|
1
|
| 1 |
IC50 = 452 nM
|
|
|
|
CP0446305
|
2-[7-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)imidazo[1,2-a]pyrimidin-2-yl]-1,3-thiazole
Show/Hide
|
C16H12N8S
|
1
|
| 1 |
IC50 = 458 nM
|
|
|
|
CP0385470
|
US9085584, 90
Show/Hide
|
C20H18FN5O
|
1
|
| 1 |
IC50 = 485 nM
|
|
|
|
CP0666464
|
2-{[(5-Fluoro-1-phenyl-1H-benzimidazol-6-yl)oxy]methyl}quinoline
Show/Hide
|
C23H16FN3O
|
1
|
| 1 |
IC50 = 494 nM
|
|
|
|
CP0508280
|
N-[[4-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]methyl]-2-methyl-8-morpholin-4-ylimidazo[1,2-a]pyrazin-3-amine
Show/Hide
|
C23H26N6O2
|
1
|
| 1 |
IC50 = 518 nM
|
|
|
|
CP0454485
|
2-methyl-8-morpholin-4-yl-N-[(4-pyridin-3-ylphenyl)methyl]imidazo[1,2-a]pyrazin-3-amine
Show/Hide
|
C23H24N6O
|
1
|
| 1 |
IC50 = 529 nM
|
|
|
|
CP0390077
|
4-[9-[(4-bromophenyl)methyl]purin-6-yl]morpholine
Show/Hide
|
C16H16BrN5O
|
1
|
| 1 |
IC50 = 530 nM
|
|
|
|
CP0468158
|
US9085584, 61
Show/Hide
|
C20H20ClN5O
|
1
|
| 1 |
IC50 = 534 nM
|
|
|
|
CP0459023
|
US9085584, 92
Show/Hide
|
C22H22FN5O
|
1
|
| 1 |
IC50 = 553 nM
|
|
|
|
CP0382539
|
US9085584, 84
Show/Hide
|
C22H20FN5O
|
1
|
| 1 |
IC50 = 565 nM
|
|
|
|
CP0389041
|
5,8-dimethyl-2-(2-phenylpyrazolo[1,5-a]pyridin-6-yl)-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C20H16N6
|
1
|
| 1 |
IC50 = 581 nM
|
|
|
|
CP0480534
|
5-methyl-2-[2-(1-methylimidazo[1,5-a]pyridin-3-yl)ethyl]-1-phenylbenzimidazole
Show/Hide
|
C24H22N4
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0709454
|
2-({[2-Isopropyl-1-(pyridin-4-yl)-1H-benzimidazol-6-yl]oxy}methyl)quinoline
Show/Hide
|
C25H22N4O
|
1
|
| 1 |
IC50 = 601 nM
|
|
|
|
CP0415901
|
US9085584, 58
Show/Hide
|
C20H18ClN5O3
|
1
|
| 1 |
IC50 = 663 nM
|
|
|
|
CP0434743
|
US9085584, 66
Show/Hide
|
C23H24FN5O
|
1
|
| 1 |
IC50 = 674 nM
|
|
|
|
CP0548234
|
5,7-dimethyl-2-(2-phenylpyrazolo[1,5-a]pyridin-6-yl)-[1,2,4]triazolo[1,5-a]pyrimidine
Show/Hide
|
C20H16N6
|
1
|
| 1 |
IC50 = 770 nM
|
|
|
|
CP0745094
|
2-({[1-(1-methyl-1H-pyrazol-4-yl)-1H-benzimidazol-6-yl]oxy}methyl)quinoline
Show/Hide
|
C21H17N5O
|
1
|
| 1 |
IC50 = 774 nM
|
|
|
|
CP0555892
|
US10138245, Example 48A
Show/Hide
|
C21H18N6
|
1
|
| 1 |
IC50 = 794 nM
|
|
|
|
CP0456767
|
US9085584, 54
Show/Hide
|
C22H24ClN5O2
|
1
|
| 1 |
IC50 = 798 nM
|
|
|
|
CP0425069
|
US9085584, 35a
Show/Hide
|
C21H20ClN5O2
|
1
|
| 1 |
IC50 = 822 nM
|
|
|
|
CP0718315
|
2-{[(2-Isobutyl-1-phenyl-1H-benzimidazol-6-yl)oxy]methyl}quinoline
Show/Hide
|
C27H25N3O
|
1
|
| 1 |
IC50 = 849 nM
|
|
|
|
CP0418084
|
US9085584, 36
Show/Hide
|
C19H19N5O2
|
1
|
| 1 |
IC50 = 850 nM
|
|
|
|
CP0417812
|
US9085584, 47
Show/Hide
|
C22H22FN5O2
|
1
|
| 1 |
IC50 = 852 nM
|
|
|
|
CP0572481
|
4-methyl-2-(2-phenyl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)quinazoline
Show/Hide
|
C21H15N5
|
1
|
| 1 |
IC50 = 884 nM
|
|
|
|
CP0408315
|
US9085584, 69
Show/Hide
|
C23H24ClN5O
|
1
|
| 1 |
IC50 = 891 nM
|
|
|
|
CP0388918
|
US9085584, 59
Show/Hide
|
C20H20ClN5O
|
1
|
| 1 |
IC50 = 936 nM
|
|
|
|
CP0567239
|
5,7-Dimethyl-2-[3-(pyridin-4-yl)-1H-benzimidazol-5-yl][1,2,4]triazolo[1,5-a]pyrimidine
Show/Hide
|
C19H15N7
|
1
|
| 1 |
IC50 = 953 nM
|
|
|
|
CP0385716
|
US9085584, 27
Show/Hide
|
C19H18ClN5O2
|
2
|
| 1 |
IC50 = 958 nM
|
|
|
| 2 |
IC50 = 970 nM
|
|
|
|
CP0462825
|
US9085584, 103
Show/Hide
|
C24H25N5O2
|
1
|
| 1 |
IC50 = 1007 nM
|
|
|
|
CP0491018
|
US9085584, 68
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
IC50 = 1007 nM
|
|
|
|
CP0545223
|
US9085584, 46
Show/Hide
|
C20H20ClN5O2
|
1
|
| 1 |
IC50 = 1035 nM
|
|
|
|
CP0546829
|
US9085584, 76
Show/Hide
|
C21H20FN5O
|
1
|
| 1 |
IC50 = 1105 nM
|
|
|
|
CP0479323
|
US9085584, 15
Show/Hide
|
C17H14ClN5O2
|
2
|
| 1 |
IC50 = 1118 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0468508
|
US9085584, 101
Show/Hide
|
C22H22FN5O
|
1
|
| 1 |
IC50 = 1125 nM
|
|
|
|
CP0462807
|
US9085584, 52
Show/Hide
|
C22H24FN5O2
|
1
|
| 1 |
IC50 = 1195 nM
|
|
|
|
CP0441480
|
(R)-2-[3-cyano-2-(2'-ethoxy-2-methyl-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C28H24FN3O3
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0542666
|
US9085584, 62
Show/Hide
|
C19H18ClN5O
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0385892
|
US9085584, 35
Show/Hide
|
C19H18ClN5O2
|
2
|
| 1 |
IC50 = 1300 nM
|
|
|
| 2 |
IC50 = 1477 nM
|
|
|
|
CP0441453
|
US9085584, 95
Show/Hide
|
C23H22FN5O2
|
1
|
| 1 |
IC50 = 1369 nM
|
|
|
|
CP0466700
|
US9085584, 26
Show/Hide
|
C18H16FN5O2
|
1
|
| 1 |
IC50 = 1380 nM
|
|
|
|
CP0470047
|
US9085584, 77
Show/Hide
|
C21H22ClN5O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0402816
|
US11419874, Example 7
Show/Hide
|
C22H22ClN5O2
|
1
|
| 1 |
IC50 = 1488 nM
|
|
|
|
CP0468099
|
US9085584, 48
Show/Hide
|
C23H25N5O2
|
1
|
| 1 |
IC50 = 1520 nM
|
|
|
|
CP0513105
|
3-[2-(6-methoxy-1H-benzimidazol-2-yl)ethyl]-1-methylimidazo[1,5-a]pyridine
Show/Hide
|
C18H18N4O
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0411935
|
US9085584, 63
Show/Hide
|
C18H16ClN5O
|
1
|
| 1 |
IC50 = 1710 nM
|
|
|
|
CP0459033
|
US9085584, 32
Show/Hide
|
C21H20ClN5O2
|
2
|
| 1 |
IC50 = 1760 nM
|
|
|
| 2 |
IC50 = 6703 nM
|
|
|
|
CP0468185
|
US9085584, 16
Show/Hide
|
C18H16ClN5O2
|
2
|
| 1 |
IC50 = 1876 nM
|
|
|
| 2 |
IC50 = 8700 nM
|
|
|
|
CP0418083
|
US9085584, 34
Show/Hide
|
C19H18ClN5O2
|
2
|
| 1 |
IC50 = 1890 nM
|
|
|
| 2 |
IC50 = 2143 nM
|
|
|
|
CP0452720
|
(R)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-8-methyl-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C28H25N3O3
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0472454
|
US9085584, 31
Show/Hide
|
C20H20ClN5O2
|
2
|
| 1 |
IC50 = 1900 nM
|
|
|
| 2 |
IC50 = 2897 nM
|
|
|
|
CP0385893
|
US9085584, 38
Show/Hide
|
C22H22ClN5O2
|
1
|
| 1 |
IC50 = 1960 nM
|
|
|
|
CP0468273
|
US9085584, 71
Show/Hide
|
C19H18ClN5O
|
1
|
| 1 |
IC50 = 2080 nM
|
|
|
|
CP0481156
|
US9085584, 39
Show/Hide
|
C21H20ClN5O2
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0527399
|
US9085584, 51
Show/Hide
|
C23H27N5O2
|
1
|
| 1 |
IC50 = 2150 nM
|
|
|
|
CP0411423
|
US9085584, 13
Show/Hide
|
C18H16ClN5O2
|
2
|
| 1 |
IC50 = 2190 nM
|
|
|
| 2 |
IC50 = 6363 nM
|
|
|
|
CP0411381
|
US9085584, 102
Show/Hide
|
C21H21N5O
|
1
|
| 1 |
IC50 = 2265 nM
|
|
|
|
CP0412276
|
US9085584, 29
Show/Hide
|
C19H18ClN5O2
|
2
|
| 1 |
IC50 = 2380 nM
|
|
|
| 2 |
IC50 = 5097 nM
|
|
|
|
CP0527413
|
US11419874, Example 8
Show/Hide
|
C22H23N5O
|
1
|
| 1 |
IC50 = 2403 nM
|
|
|
|
CP0418082
|
US9085584, 33
Show/Hide
|
C20H17ClF3N5O2
|
2
|
| 1 |
IC50 = 2500 nM
|
|
|
| 2 |
IC50 = 3417 nM
|
|
|
|
CP0418081
|
US9085584, 30
Show/Hide
|
C22H20ClF2N5O
|
2
|
| 1 |
IC50 = 2573 nM
|
|
|
| 2 |
IC50 = 3920 nM
|
|
|
|
CP0550845
|
US9085584, 87
Show/Hide
|
C19H16ClN5O
|
1
|
| 1 |
IC50 = 2594 nM
|
|
|
|
CP0538395
|
US9085584, 94
Show/Hide
|
C23H22ClN5O2
|
1
|
| 1 |
IC50 = 2719 nM
|
|
|
|
CP0385890
|
US9085584, 20
Show/Hide
|
C20H18ClN5O2
|
2
|
| 1 |
IC50 = 2760 nM
|
|
|
| 2 |
IC50 = 8162 nM
|
|
|
|
CP0409878
|
US9085584, 21
Show/Hide
|
C21H18ClF2N5O
|
2
|
| 1 |
IC50 = 2820 nM
|
|
|
| 2 |
IC50 = 7047 nM
|
|
|
|
CP0411424
|
US9085584, 53
Show/Hide
|
C20H18FN5O2
|
1
|
| 1 |
IC50 = 2830 nM
|
|
|
|
CP0409797
|
US9085584, 78
Show/Hide
|
C22H25N5O
|
1
|
| 1 |
IC50 = 2845 nM
|
|
|
|
CP0470058
|
US9085584, 72
Show/Hide
|
C22H22FN5O
|
1
|
| 1 |
IC50 = 2865 nM
|
|
|
|
CP0385894
|
US9085584, 18
Show/Hide
|
C18H16ClN5O2
|
2
|
| 1 |
IC50 = 3010 nM
|
|
|
| 2 |
IC50 = 8418 nM
|
|
|
|
CP0488803
|
US9085584, 19
Show/Hide
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C19H18ClN5O2
|
1
|
| 1 |
IC50 = 3010 nM
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|
CP0499854
|
US9085584, 37
Show/Hide
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C20H18ClN5O2
|
1
|
| 1 |
IC50 = 3080 nM
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|
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CP0403392
|
US9085584, 113
Show/Hide
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C23H22ClN5O2
|
1
|
| 1 |
IC50 = 3190 nM
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|
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CP0472607
|
US9085584, 25
Show/Hide
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C20H18ClN5O2
|
2
|
| 1 |
IC50 = 3260 nM
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|
|
| 2 |
IC50 = 7333 nM
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|
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CP0422627
|
US9085584, 40
Show/Hide
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C20H18ClN5O2
|
2
|
| 1 |
IC50 = 3470 nM
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|
|
| 2 |
IC50 = 8707 nM
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CP0474331
|
US9085584, 65
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C20H20FN5O
|
1
|
| 1 |
IC50 = 3545 nM
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|
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CP0499839
|
US9085584, 14
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C20H20ClN5O2
|
1
|
| 1 |
IC50 = 3580 nM
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|
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|
CP0456754
|
US9085584, 49
Show/Hide
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C20H18ClN5O2
|
1
|
| 1 |
IC50 = 3760 nM
|
|
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|
CP0527414
|
US9085584, 100
Show/Hide
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C22H23N5O2
|
1
|
| 1 |
IC50 = 3856 nM
|
|
|
|
CP0390440
|
US9085584, 64
Show/Hide
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C20H20ClN5O
|
1
|
| 1 |
IC50 = 3870 nM
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|
|
|
CP0524289
|
US9085584, 67
Show/Hide
|
C21H23N5O
|
1
|
| 1 |
IC50 = 3905 nM
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|
|
|
CP0501659
|
(R)-2-[3-cyano-2-(2'-ethoxy-3-methyl-biphenyl-4-yl)-6-fluoro-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C28H24FN3O3
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0413987
|
US9085584, 85
Show/Hide
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C21H20ClN5O
|
1
|
| 1 |
IC50 = 4325 nM
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|
|
|
CP0546854
|
US9085584, 43a
Show/Hide
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C19H16ClN5O2
|
1
|
| 1 |
IC50 = 4510 nM
|
|
|
|
CP0459013
|
US9085584, 81
Show/Hide
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C23H25N5O
|
1
|
| 1 |
IC50 = 5384 nM
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|
|
|
CP0402820
|
US9085584, 80
Show/Hide
|
C22H22FN5O
|
1
|
| 1 |
IC50 = 5405 nM
|
|
|
|
CP0429589
|
US9085584, 82
Show/Hide
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C19H18ClN5O
|
1
|
| 1 |
IC50 = 5615 nM
|
|
|
|
CP0413531
|
US9085584, 17
Show/Hide
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C18H16ClN5O2
|
2
|
| 1 |
IC50 = 5720 nM
|
|
|
| 2 |
IC50 = 10200 nM
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|
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|
CP0515365
|
US9085584, 86
Show/Hide
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C19H16FN5O
|
1
|
| 1 |
IC50 = 5750 nM
|
|
|
|
CP0524244
|
US9085584, 96
Show/Hide
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C21H17ClF3N5O2
|
1
|
| 1 |
IC50 = 5945 nM
|
|
|
|
CP0381477
|
US9085584, 44
Show/Hide
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C19H18ClN5O2
|
1
|
| 1 |
IC50 = 6037 nM
|
|
|
|
CP0402800
|
US9085584, 93
Show/Hide
|
C20H18ClN5O2
|
1
|
| 1 |
IC50 = 6107 nM
|
|
|
|
CP0513101
|
2-(2-imidazo[1,5-a]pyridin-3-ylethyl)-5-methyl-1-phenylbenzimidazole
Show/Hide
|
C23H20N4
|
1
|
| 1 |
IC50 = 6800 nM
|
|
|
|
CP0456772
|
US9085584, 50
Show/Hide
|
C21H21N5O2
|
1
|
| 1 |
IC50 = 7120 nM
|
|
|
|
CP0396419
|
US9085584, 32a
Show/Hide
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C23H22ClN5O2
|
1
|
| 1 |
IC50 = 7390 nM
|
|
|
|
CP0459949
|
US9085584, 96c
Show/Hide
|
C20H15F4N5O2
|
1
|
| 1 |
IC50 = 7460 nM
|
|
|
|
CP0481502
|
US9085584, 110d
Show/Hide
|
C21H17F4N5O3
|
1
|
| 1 |
IC50 = 7600 nM
|
|
|
|
CP0462003
|
US9085584, 70
Show/Hide
|
C18H16ClN5O
|
1
|
| 1 |
IC50 = 8620 nM
|
|
|
|
CP0543527
|
US9085584, 83
Show/Hide
|
C22H22ClN5O
|
1
|
| 1 |
IC50 = 8815 nM
|
|
|
|
CP0382548
|
US9085584, 96b
Show/Hide
|
C22H20F3N5O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0382560
|
US9085584, 73
Show/Hide
|
C20H19N5O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0440527
|
US9085584, 110b
Show/Hide
|
C21H17F4N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0491021
|
US9085584, 103b
Show/Hide
|
C19H15ClF3N5O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0546676
|
US9085584, 96a
Show/Hide
|
C21H17F4N5O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0000847
|
(2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11(16),12,14-tetraene-4,7-dione
Show/Hide
|
C22H19N3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0010658
|
5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Show/Hide
|
C22H30N6O4S
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
|
CP0384486
|
N-[3-(4,5-diethyl-6-oxo-1H-pyrimidin-2-yl)-4-propoxyphenyl]-2-(4-methylpiperazin-1-yl)acetamide
Show/Hide
|
C24H35N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0176508
|
[4-[3-(3-fluoro-4-methoxyphenyl)-5-(2-methylphenyl)-3,4-dihydropyrazol-2-yl]phenyl]-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C29H31FN4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0365459
|
[4-[5-tert-butyl-3-(3,5-difluoro-4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]phenyl]-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C26H32F2N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0419693
|
[4-[5-tert-butyl-3-(2,3-difluoro-4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]phenyl]-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C26H32F2N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0444327
|
[4-[3-(4-methoxyphenyl)-5-(2-methylphenyl)-3,4-dihydropyrazol-2-yl]phenyl]-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C29H32N4O2
|
2
|
| 1 |
IC50 = 32300 nM
|
|
|
| 2 |
IC50 = 49500 nM
|
|
|
|
CP0419692
|
N-(2-hydroxyethyl)-4-[3-(4-methoxyphenyl)-5-(2-methylphenyl)-3,4-dihydropyrazol-2-yl]benzamide
Show/Hide
|
C26H27N3O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0389046
|
2-[2-(4-methoxypyridin-2-yl)-3H-benzimidazol-5-yl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C20H17N7O
|
1
|
| 1 |
IC50 > 280 nM
|
|
|
|
CP0476922
|
2-[2-(3,5-dimethoxyphenyl)imidazo[1,2-a]pyrimidin-7-yl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C21H19N7O2
|
1
|
| 1 |
IC50 > 280 nM
|
|
|
|
CP0446304
|
4-[6-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-1H-benzimidazol-2-yl]-1,3-oxazole
Show/Hide
|
C17H13N7O
|
1
|
| 1 |
IC50 > 300 nM
|
|
|
|
CP0666462
|
2-({[1-(Pyridazin-4-yl)-1H-benzimidazol-6-yl]oxy}methyl)quinoline
Show/Hide
|
C21H15N5O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0666463
|
2-({[1-(Pyridin-4-ylmethyl)-1H-benzimidazol-6-yl]oxy}methyl)quinoline
Show/Hide
|
C23H18N4O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0718317
|
2-({[1-Phenyl-2-(trifluoromethyl)-1H-benzimidazol-6-yl]oxy}methyl)quinoline
Show/Hide
|
C24H16F3N3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0829251
|
2-{[(3-Phenyl-1,2-benzoxazol-5-yl)oxy]methyl}quinoline
Show/Hide
|
C23H16N2O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0839573
|
2-({[1-(1-Methyl-1H-pyrazol-3-yl)-1H-benzimidazol-6-yl]oxy}methyl)quinoline
Show/Hide
|
C21H17N5O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0840246
|
2-{[(1-Cyclohexyl-1H-benzimidazol-6-yl)oxy]methyl}quinoline
Show/Hide
|
C23H23N3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0842044
|
2-({[1-(Pyrimidin-2-yl)-1H-benzimidazol-6-yl]oxy}methyl)quinoline
Show/Hide
|
C21H15N5O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0875473
|
2-{[(1-Phenyl-1H-indazol-6-yl)oxy]methyl}quinoline
Show/Hide
|
C23H17N3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0941915
|
2-{[(1-Phenyl-1H-indol-6-yl)oxy]methyl}quinoline
Show/Hide
|
C24H18N2O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0476919
|
2-(2-benzyl-3H-benzimidazol-5-yl)-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C21H18N6
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0476920
|
2-[6-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)-1H-benzimidazol-2-yl]quinoxaline
Show/Hide
|
C22H16N8
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0482324
|
2-[2-(2-chloro-4-fluorophenyl)imidazo[1,2-a]pyrimidin-7-yl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C19H13ClFN7
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0482325
|
2-[2-(4-bromophenyl)imidazo[1,2-a]pyrimidin-7-yl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C19H14BrN7
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0567240
|
5,8-dimethyl-2-[2-[2-(trifluoromethyl)phenyl]-3H-benzimidazol-5-yl]-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C21H15F3N6
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0572483
|
5,8-dimethyl-2-(2-pyrazin-2-yl-3H-benzimidazol-5-yl)-[1,2,4]triazolo[1,5-a]pyrazine
Show/Hide
|
C18H14N8
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0257911
|
(10S,15S)-13-ethyl-10-(5-ethylfuran-2-yl)-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraene-12,14-dione
Show/Hide
|
C21H21N3O3
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0458493
|
(R)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-5,6-difluoro-quinolin-4-ylamino]-propionic acid
Show/Hide
|
C27H21F2N3O3
|
1
|
| 1 |
IC50 > 4000 nM
|
|
|
|
CP0268684
|
(2S,8R)-2-(5-ethylthiophen-2-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione
Show/Hide
|
C21H21N3O2S
|
1
|
| 1 |
IC50 > 4000 nM
|
|
|
|
CP0396020
|
5,7-dimethyl-2-(2-pyrimidin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-[1,2,4]triazolo[1,5-a]pyrimidine
Show/Hide
|
C17H13N9
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
