| Compound ID |
Compound Name |
Compound Formula |
|
CP0505279
|
(3S)-1-(1,3-BENZODIOXOL-5-YLMETHYL)-3-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PIPERIDINE
Show/Hide
|
C22H23N3O3
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0505278
|
1-(1,3-benzodioxol-5-ylmethyl)-N-(4-imidazol-1-ylphenyl)piperidin-3-amine
Show/Hide
|
C22H24N4O2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0505277
|
3-(4-(1H-imidazol-1-yl)phenoxy)-1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidine
Show/Hide
|
C22H23N3O3
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0153439
|
(S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic acid
Show/Hide
|
C7H15N3O2S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0521166
|
3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-3-yloxy)-6-(1H-imidazol-1-yl)pyridazine
Show/Hide
|
C20H21N5O3
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0747739
|
L-nitro arginine methyl ester
Show/Hide
|
C7H16ClN5O4
|
1
|
| 1 |
IC50 = 830 nM
|
|
|
|
CP0902858
|
2-[[[[2-(1-Iminoethyl)amino]ethyl]thio]methyl]-D-valine dihydrochloride
Show/Hide
|
C9H22Cl2N4O2S
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0403594
|
N'-[1-(thian-4-yl)-2,3-dihydroindol-6-yl]thiophene-2-carboximidamide
Show/Hide
|
C18H21N3S2
|
1
|
| 1 |
IC50 = 1120 nM
|
|
|
|
CP0485337
|
(R)-1-(4-((1-(benzo[d][1,3]dioxol-5-ylmethyl)pyrrolidin-2-yl)methoxy)phenyl)-1H-imidazole
Show/Hide
|
C22H23N3O3
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0871803
|
N-(1-(1-methylazepan-4-yl)-1H-indol-6-yl)furan-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4O
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0867182
|
N-(1-(1-methylpiperidin-4-yl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C21H30Cl2N4S
|
1
|
| 1 |
IC50 = 1340 nM
|
|
|
|
CP0688010
|
N-(1-(2-(dimethylamino)ethyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H28Cl2N4S
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0099519
|
US8618286, 3
Show/Hide
|
C19H22N4O2S
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0857490
|
(S)-2-amino-5-(3-methylguanidino)pentanoic acid dihydrochloride
Show/Hide
|
C7H18Cl2N4O2
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0418062
|
methyl (2S)-2-amino-5-[(N'-methylcarbamimidoyl)amino]pentanoate
Show/Hide
|
C8H18N4O2
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0052287
|
(2S)-5-{[(Z)-amino(imino)methyl]amino}-2-(methylamino)pentanoic acid
Show/Hide
|
C7H16N4O2
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0053263
|
(2S)-2-azaniumyl-5-[(N'-methylcarbamimidoyl)amino]pentanoate
Show/Hide
|
C7H16N4O2
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0493705
|
2-((4-(1H-imidazol-1-yl)phenoxy)methyl)-1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidine
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0403595
|
N'-(1-piperidin-4-yl-2,3-dihydroindol-6-yl)thiophene-2-carboximidamide
Show/Hide
|
C18H22N4S
|
1
|
| 1 |
IC50 = 2390 nM
|
|
|
|
CP0887630
|
N-(3-(1-methylpyrrolidin-3-yl)-1H-indol-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C18H22Cl2N4S
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0366412
|
US8618286, 4
Show/Hide
|
C19H24N4OS
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0746845
|
S-[2-[(1-Iminoethyl)aminolethyl]-2-methyl-L-cysteine dihydrochloride
Show/Hide
|
C7H18Cl2N4O2S
|
1
|
| 1 |
IC50 = 3100 nM
|
|
|
|
CP0902857
|
S-[2-[(1-Iminoethyl)amino]ethyl]-2-ethyl-L-cysteine dihydrochloride
Show/Hide
|
C8H20Cl2N4O2S
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0454913
|
N'-[1-[2-(2-hydroxyethylamino)ethyl]-2,3-dihydroindol-6-yl]thiophene-2-carboximidamide
Show/Hide
|
C17H22N4OS
|
1
|
| 1 |
IC50 = 3410 nM
|
|
|
|
CP0321630
|
US8618286, 10
Show/Hide
|
C16H20N4OS
|
1
|
| 1 |
IC50 = 3740 nM
|
|
|
|
CP0436022
|
2-[(S)-2-Amino-5-(2-methyl-isothioureido)-pentanoylamino]-3-(S)-phenyl-propionic acid
Show/Hide
|
C16H24N4O3S
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0040036
|
(S)-5-Acetimidoylamino-2-amino-pent
Show/Hide
|
C7H15N3O2
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0888278
|
2-[[[2-[(1-Iminoethyl)amino]ethyllthiolmethyl]-O-methyl-D-serine dihydrochloride
Show/Hide
|
C8H20Cl2N4O3S
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0436023
|
(S)-2-(S)-Amino-3-methyl-5-(2-methyl-isothioureido)-pentanoic acid tert-butyl ester
Show/Hide
|
C12H25N3O2S
|
1
|
| 1 |
IC50 = 4500 nM
|
|
|
|
CP0846661
|
N-(1-(2-(piperidin-1-yl)ethyl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4S
|
1
|
| 1 |
IC50 = 4610 nM
|
|
|
|
CP0895914
|
(+/-)-N-(1-(Pyrrolidin-3-yl)indolin-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C17H22Cl2N4S
|
1
|
| 1 |
IC50 = 5450 nM
|
|
|
|
CP0403591
|
N'-[1-[2-[(3R)-3-hydroxypyrrolidin-1-yl]ethyl]-2,3-dihydroindol-6-yl]thiophene-2-carboximidamide
Show/Hide
|
C19H24N4OS
|
1
|
| 1 |
IC50 = 6790 nM
|
|
|
|
CP0743881
|
S-[2-(1-Iminoethylamino)ethyl]-2-methyl-(D/L)-cysteine bistrifluoroacetate
Show/Hide
|
C11H18F6N4O6S
|
1
|
| 1 |
IC50 = 7200 nM
|
|
|
|
CP0443091
|
US8618286, 9
Show/Hide
|
C17H22N4OS
|
1
|
| 1 |
IC50 = 7250 nM
|
|
|
|
CP0858766
|
N-(1-(1-methylazepan-4-yl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4S
|
1
|
| 1 |
IC50 = 7600 nM
|
|
|
|
CP0894438
|
N-(3-(1-azabicyclo[2.2.2]oct-2-en-3-yl)-1H-indol-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H22Cl2N4S
|
1
|
| 1 |
IC50 = 8400 nM
|
|
|
|
CP0476584
|
N'-(1-pyrrolidin-3-yl-2,3-dihydroindol-6-yl)thiophene-2-carboximidamide
Show/Hide
|
C17H20N4S
|
1
|
| 1 |
IC50 = 8940 nM
|
|
|
|
CP0893178
|
N-(3-(1-methylpiperidin-4-yl)-1H-indol-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H24Cl2N4S
|
1
|
| 1 |
IC50 = 9300 nM
|
|
|
|
CP0846662
|
N-(1-(2-(1-methylpiperidin-2-yl)ethyl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C21H28Cl2N4S
|
1
|
| 1 |
IC50 = 9800 nM
|
|
|
|
CP0851757
|
N-(1-(3-(Dimethylamino)propyl)-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H26Cl2N4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0854008
|
N-(1-(2-(2-Hydroxyethylamino)ethyl)indolin-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C17H24Cl2N4OS
|
1
|
| 1 |
IC50 = 10100 nM
|
|
|
|
CP0895048
|
N-(1-(2-(Pyrrolidin-1-yl)acetyl)indolin-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H24Cl2N4OS
|
1
|
| 1 |
IC50 = 10500 nM
|
|
|
|
CP0108183
|
US8618286, 2
Show/Hide
|
C20H26N4OS
|
1
|
| 1 |
IC50 = 10600 nM
|
|
|
|
CP0252728
|
US8618286, 6
Show/Hide
|
C17H22N4OS
|
1
|
| 1 |
IC50 = 10900 nM
|
|
|
|
CP0898980
|
N-(1-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C21H26Cl2N4S
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0867649
|
N-(2-Oxo-1-(2-(pyrrolidin-1-yl)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4OS
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0899695
|
N-(1-(2-(dimethylamino)ethyl)indolin-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C17H24Cl2N4S
|
1
|
| 1 |
IC50 = 11400 nM
|
|
|
|
CP0859166
|
N-(1-(2-(Diethylamino)ethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H28Cl2N4OS
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0881747
|
(2R)-2-Amino-3[[2-[(1-iminoethyl)amino]ethyl]sulfonyl]-2-methylpropanoic acid dihydrochloride
Show/Hide
|
C7H18Cl2N4O4S
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0938036
|
(2R)-2-Amino-3[[2-[(1-iminoethyl)amino]ethyl]sulfinyl]-2-methylpropanoicacid dihydrochloride
Show/Hide
|
C7H18Cl2N4O3S
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0734618
|
N-(3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H22Cl2N4S
|
1
|
| 1 |
IC50 = 12300 nM
|
|
|
|
CP0887415
|
(+/-)-N-(1-(pyrrolidin-3-yl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H26Cl2N4S
|
1
|
| 1 |
IC50 = 13500 nM
|
|
|
|
CP0918473
|
rac-N-(1-(2-(1-methylpyrrolidin-2-yl)ethyl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4S
|
1
|
| 1 |
IC50 = 14000 nM
|
|
|
|
CP0861066
|
trans-(+/-)-N-(3-(3-(methylamino)cyclohexyl)-1H-indol-5-yl)thiophene-2-carboximidamide hydrochloride
Show/Hide
|
C20H25ClN4S
|
1
|
| 1 |
IC50 = 14500 nM
|
|
|
|
CP0918475
|
N-(1-(1-methylpiperidin-4-yl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H24Cl2N4S
|
1
|
| 1 |
IC50 = 15000 nM
|
|
|
|
CP0919195
|
N-(1-(2-(dimethylamino)ethyl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C17H22Cl2N4S
|
1
|
| 1 |
IC50 = 15700 nM
|
|
|
|
CP0864145
|
N-(1-(2-(pyrrolidin-1-yl)ethyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C21H30Cl2N4S
|
1
|
| 1 |
IC50 = 16900 nM
|
|
|
|
CP0919242
|
(S)-N-(1-(2-(1-methylpyrrolidin-2-yl)ethyl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4S
|
1
|
| 1 |
IC50 = 17000 nM
|
|
|
|
CP0868523
|
methyl 3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-ylcarbamimidothioate dihydrochloride
Show/Hide
|
C16H22Cl2N4S
|
1
|
| 1 |
IC50 = 17100 nM
|
|
|
|
CP0910864
|
N-{1-[3-(Adamantan-1-ylamino)-propyl]-1H-indol-5-yl}-thiophene-2-carboxamidine dihydrochloride
Show/Hide
|
C26H34Cl2N4S
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0667837
|
cis-(+/-)-N-(3-(3-(Ethylamino)cyclohexyl)-1H-indol-5-yl)thiophene-2-carboximidamide hydrochloride
Show/Hide
|
C21H27ClN4S
|
1
|
| 1 |
IC50 = 19200 nM
|
|
|
|
CP0777464
|
N-(3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H22Cl2N4S
|
1
|
| 1 |
IC50 = 20000 nM
|
|
|
|
CP0852924
|
N-(1-(2-(piperidin-1-yl)ethyl)-1H-indol-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4S
|
1
|
| 1 |
IC50 = 21000 nM
|
|
|
|
CP0895911
|
(+/-)-N-(1-(1-Methylpyrrolidin-3-yl)indolin-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C18H24Cl2N4S
|
1
|
| 1 |
IC50 = 21200 nM
|
|
|
|
CP0893901
|
(R)-N-(1-(2-(1-methylpyrrolidin-2-yl)ethyl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4S
|
1
|
| 1 |
IC50 = 22000 nM
|
|
|
|
CP0847604
|
(+/-)-N-(3-(4-(dimethylamino)cyclohex-1-enyl)-1H-indol-5-yl)thiophene-2-carboximidamide hydrochloride
Show/Hide
|
C21H25ClN4S
|
1
|
| 1 |
IC50 = 24000 nM
|
|
|
|
CP0676856
|
(S)-N-(1-(2-(1-Methylpyrrolidin-2-yl)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C21H30Cl2N4S
|
1
|
| 1 |
IC50 = 25700 nM
|
|
|
|
CP0847605
|
cis-N-(3-(4-(dimethylamino)cyclohexyl)-1H-indol-5-yl)thiophene-2-carboximidamide hydrochloride
Show/Hide
|
C21H27ClN4S
|
1
|
| 1 |
IC50 = 26500 nM
|
|
|
|
CP0898981
|
N-(1-(quinuclidin-3-yl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H24Cl2N4S
|
1
|
| 1 |
IC50 = 29000 nM
|
|
|
|
CP0918474
|
N-(1-(2-(1-methylpyrrolidin-2-yl)ethyl)-1H-indol-5-yl)furan-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4O
|
1
|
| 1 |
IC50 = 32700 nM
|
|
|
|
CP0535583
|
US8618286, 13
Show/Hide
|
C20H26N4S2
|
1
|
| 1 |
IC50 = 33100 nM
|
|
|
|
CP0666251
|
(R)-N-(1-(2-(1-Methylpyrrolidin-2-yl)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C21H30Cl2N4S
|
1
|
| 1 |
IC50 = 33200 nM
|
|
|
|
CP0904455
|
N-(1-(3-(cyclopropylamino)propyl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H24Cl2N4S
|
1
|
| 1 |
IC50 = 34000 nM
|
|
|
|
CP0666250
|
N-(1-(2-(Dimethylamino)ethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C18H24Cl2N4OS
|
1
|
| 1 |
IC50 = 35000 nM
|
|
|
|
CP0899149
|
N-(1-(3-morpholinopropyl)-1H-indol-6-yl)furan-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4O2
|
1
|
| 1 |
IC50 = 36000 nM
|
|
|
|
CP0704838
|
cis-N-(3-(4-(methylamino)cyclohexyl)-1H-indol-5-yl)thiophene-2-carboximidamide hydrochloride
Show/Hide
|
C20H25ClN4S
|
1
|
| 1 |
IC50 = 36300 nM
|
|
|
|
CP0905339
|
N-(1-(2-(Pyrrolidin-1-yl)ethyl)indolin-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H26Cl2N4S
|
1
|
| 1 |
IC50 = 37300 nM
|
|
|
|
CP0870593
|
N-(1-(1-(2-Hydroxyethyl)piperidin-4-yl)indolin-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H28Cl2N4OS
|
1
|
| 1 |
IC50 = 39300 nM
|
|
|
|
CP0930876
|
N-(1-(Piperidin-4-yl)indolin-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C18H24Cl2N4S
|
1
|
| 1 |
IC50 = 40500 nM
|
|
|
|
CP0364946
|
US8618286, 15
Show/Hide
|
C19H26N4S2
|
1
|
| 1 |
IC50 = 40700 nM
|
|
|
|
CP0858765
|
N-(1-(3-morpholinopropyl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4OS
|
1
|
| 1 |
IC50 = 41600 nM
|
|
|
|
CP0120800
|
US8618286, 25
Show/Hide
|
C19H24N4S2
|
1
|
| 1 |
IC50 = 43600 nM
|
|
|
|
CP0529326
|
US8618286, 21
Show/Hide
|
C20H26N4S2
|
1
|
| 1 |
IC50 = 49600 nM
|
|
|
|
CP0873763
|
cis-(+/-)-N-(3-(3-(methylamino)cyclohexyl)-1H-indol-5-yl)thiophene-2-carboximidamide hydrochloride
Show/Hide
|
C20H25ClN4S
|
1
|
| 1 |
IC50 = 54100 nM
|
|
|
|
CP0870508
|
trans-(+/-)-N-(3-(3-(Ethylamino)cyclohexyl)-1H-indol-5-yl)thiophene-2-carboximidamide hydrochloride
Show/Hide
|
C21H27ClN4S
|
1
|
| 1 |
IC50 = 54200 nM
|
|
|
|
CP0859143
|
N-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H24Cl2N4S
|
1
|
| 1 |
IC50 = 58200 nM
|
|
|
|
CP0899694
|
N-(1-(1-Methylpiperidin-4-yl)indolin-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H26Cl2N4S
|
1
|
| 1 |
IC50 = 58200 nM
|
|
|
|
CP0676501
|
N-(3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-yl)furan-2-carboximidamide dihydrochloride
Show/Hide
|
C19H22Cl2N4O
|
1
|
| 1 |
IC50 = 58500 nM
|
|
|
|
CP0305558
|
US8618286, 16
Show/Hide
|
C17H22N4OS2
|
1
|
| 1 |
IC50 = 58700 nM
|
|
|
|
CP0888586
|
N-(1-(2-(dimethylamino)ethyl)-1H-indol-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C17H22Cl2N4S
|
1
|
| 1 |
IC50 = 60000 nM
|
|
|
|
CP0173856
|
US8618286, 26
Show/Hide
|
C17H22N4OS2
|
1
|
| 1 |
IC50 = 60100 nM
|
|
|
|
CP0108111
|
US8618286, 12
Show/Hide
|
C17H22N4S2
|
1
|
| 1 |
IC50 = 62900 nM
|
|
|
|
CP0887882
|
N-(1-(4-(dimethylamino)butyl)-1H-indol-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H26Cl2N4S
|
1
|
| 1 |
IC50 = 66000 nM
|
|
|
|
CP0148844
|
US8618286, 27
Show/Hide
|
C17H22N4S2
|
1
|
| 1 |
IC50 = 66500 nM
|
|
|
|
CP0915337
|
(+/-)-N-(1-(2-(1-methylpyrrolidin-2-yl)ethyl)-1H-indol-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4S
|
1
|
| 1 |
IC50 = 68000 nM
|
|
|
|
CP0852925
|
N-(1-(3-morpholinopropyl)-1H-indol-6-yl)thiophene-3-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4OS
|
1
|
| 1 |
IC50 = 70000 nM
|
|
|
|
CP0147894
|
US8618286, 8
Show/Hide
|
C16H20N4S2
|
1
|
| 1 |
IC50 = 70600 nM
|
|
|
|
CP0871802
|
(S)-N-(1-(2-(1-methylpyrrolidin-2-yl)ethyl)-1H-indol-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4S
|
1
|
| 1 |
IC50 = 72000 nM
|
|
|
|
CP0877749
|
(R)-N-(1-(2-(1-methylpyrrolidin-2-yl)ethyl)-1H-indol-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4S
|
1
|
| 1 |
IC50 = 72000 nM
|
|
|
|
CP0917442
|
N-(1-(2-(2-Hydroxyethylamino)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C18H26Cl2N4OS
|
1
|
| 1 |
IC50 = 73000 nM
|
|
|
|
CP0919373
|
S-[(1R)-2-[(1-Iminoethyl)amino]-1-methylethyl]-2-methyl-L-cysteine dihydrochloride
Show/Hide
|
C8H20Cl2N4O2S
|
1
|
| 1 |
IC50 = 74000 nM
|
|
|
|
CP0371501
|
US8618286, 29
Show/Hide
|
C18H22N4S2
|
1
|
| 1 |
IC50 = 76800 nM
|
|
|
|
CP0888580
|
N-(1-(3-morpholinopropyl)-1H-indol-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4OS
|
1
|
| 1 |
IC50 = 82000 nM
|
|
|
|
CP0560837
|
US8618286, 24
Show/Hide
|
C17H22N4S2
|
1
|
| 1 |
IC50 = 82300 nM
|
|
|
|
CP0387862
|
N'-[1-[4-(methylamino)cyclohexyl]-2,3-dihydroindol-6-yl]thiophene-2-carboximidamide
Show/Hide
|
C20H26N4S
|
1
|
| 1 |
IC50 = 83000 nM
|
|
|
|
CP0868522
|
N-((3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-5-yl)methyl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H24Cl2N4S
|
1
|
| 1 |
IC50 = 85000 nM
|
|
|
|
CP0917440
|
N-(1-(2-(Isopropylamino)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H28Cl2N4S
|
1
|
| 1 |
IC50 = 89400 nM
|
|
|
|
CP0895913
|
(+/-)-N-(1-(Piperidin-3-yl)indolin-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C18H24Cl2N4S
|
1
|
| 1 |
IC50 = 94000 nM
|
|
|
|
CP0915579
|
N-(1-(3-(dimethylamino)propyl)-1H-indol-5-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C18H24Cl2N4S
|
1
|
| 1 |
IC50 = 95100 nM
|
|
|
|
CP0871044
|
N-(1-(3-morpholinopropyl)-1H-indol-6-yl)furan-3-carboximidamide dihydrochloride
Show/Hide
|
C20H26Cl2N4O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0888604
|
N-(1-(4-(1H-imidazol-1-yl)butyl)-1H-indol-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H23Cl2N5S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0694923
|
N-(1-(Piperidin-4-yl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H26Cl2N4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0851758
|
N-(2-Oxo-1-(2-(piperidin-1-yl)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C21H28Cl2N4OS
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0853298
|
N-(1-(2-(Diethylamino)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H30Cl2N4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0853299
|
N-(1-(1-Methylpiperidin-4-yl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H28Cl2N4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0859168
|
N-(1-(2-(Dimethylamino)ethyl)-8-fluoro-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C18H25Cl2FN4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0873350
|
(+/-)-N-(1-(2-(1-Methylpyrrolidin-2-yl)ethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C21H28Cl2N4OS
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0873351
|
N-(1-(3-(Pyrrolidin-1-yl)propyl)-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C21H28Cl2N4OS
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0403593
|
N'-(1-cyclohexyl-2,3-dihydroindol-6-yl)thiophene-2-carboximidamide
Show/Hide
|
C19H23N3S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0448315
|
N'-[1-(oxan-4-yl)-2,3-dihydroindol-6-yl]thiophene-2-carboximidamide
Show/Hide
|
C18H21N3OS
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0850822
|
(+/-)-N-(1-(2-(1-methylpyrrolidin-2-yl)ethyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C22H32Cl2N4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0867192
|
N-(1-(2-(methylamino)ethyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C18H26Cl2N4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0867193
|
N-(1-(piperidin-4-yl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H28Cl2N4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0867561
|
N-(1-(2-(piperidin-1-yl)ethyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C22H32Cl2N4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0867563
|
(+/-)-N-(1-(1-methylpyrrolidin-3-yl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C20H28Cl2N4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0853757
|
N-(1-(3-(2-Hydroxyethylamino)propyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H28Cl2N4OS
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0853933
|
N-(1-(2-(Ethyl(methyl)amino)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H28Cl2N4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0912490
|
N-(1-(2-((2-Hydroxyethyl)(methyl)amino)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C19H28Cl2N4OS
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0917441
|
N-(1-(3-(Methylamino)propyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C18H26Cl2N4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0927411
|
N-(1-(2-(Methylamino)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C17H24Cl2N4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0948496
|
N-(1-(2-(Ethylamino)ethyl)-1,2,3,4-tetrahydroquinolin-6-yl)-thiophene-2-carboximidamide dihydrochloride
Show/Hide
|
C18H26Cl2N4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0065273
|
US8618286, 5
Show/Hide
|
C17H20N4O2S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0107935
|
US8618286, 1
Show/Hide
|
C20H24N4O2S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0120647
|
US8618286, 7
Show/Hide
|
C17H22N4OS
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
