| Compound ID |
Compound Name |
Compound Formula |
|
CP0030809
|
tert-butyl 6-[2-chloro-4-(3-methylimidazol-4-yl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
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|
C26H26ClN7O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0030351
|
tert-butyl 6-[2-chloro-4-[4-(dimethylamino)piperidine-1-carbonyl]anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C30H36ClN7O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0029562
|
tert-butyl 6-[2-chloro-4-(1,1-dioxo-1,4-thiazinane-4-carbonyl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C27H29ClN6O5S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0023842
|
tert-butyl 6-[2-chloro-4-(dimethylcarbamoyl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
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|
C25H27ClN6O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0023726
|
tert-butyl 6-[4-(azetidine-1-carbonyl)-2-chloroanilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
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|
C26H27ClN6O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0027579
|
N-(2,6-diethylphenyl)-1-methyl-8-[4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)anilino]-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide
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|
C35H39F3N8O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0032521
|
9-cyclopentyl-2-[2-methoxy-4-(1-methylpiperidin-4-yl)oxyanilino]-7-methylpurin-8-one
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|
C24H32N6O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0029561
|
[3-chloro-4-[[2-(1-methylpyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl]amino]phenyl]-(1,1-dioxo-1,4-thiazinan-4-yl)methanone
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|
C22H21ClN6O3S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0380192
|
US11046688, Example 32
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|
C22H20N8O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0409721
|
US11046688, Example 96
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|
C23H22N8O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0455282
|
US10479788, Example 37
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|
C22H23N7O
|
3
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 330 nM
|
|
|
| 3 |
Ki = 3.3 nM
|
|
|
|
CP0023705
|
4-[[4-amino-6-(tert-butylamino)-5-cyanopyridin-2-yl]amino]benzamide
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|
C17H20N6O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0024754
|
tert-butyl 6-[2-chloro-4-(4-methoxypiperidine-1-carbonyl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C29H33ClN6O4
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0033865
|
US10479788, Example 77
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|
C24H29N7O
|
3
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
| 3 |
Ki = 0.2 nM
|
|
|
|
CP0380193
|
US10479788, Example 58
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|
C22H23N7O
|
3
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
IC50 = 280 nM
|
|
|
| 3 |
Ki = 2.8 nM
|
|
|
|
CP0329773
|
US10479788, Example 55
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|
C24H27N7O
|
3
|
| 1 |
IC50 = 12 nM
|
|
|
| 2 |
IC50 = 130 nM
|
|
|
| 3 |
Ki = 1.3 nM
|
|
|
|
CP0023725
|
[3-chloro-4-[[2-(1-methylpyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl]amino]phenyl]-(4-methoxypiperidin-1-yl)methanone
Show/Hide
|
C24H25ClN6O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0020307
|
tert-butyl 6-[2-chloro-4-(1-methylpyrazol-4-yl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C26H26ClN7O2
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0029560
|
3-chloro-N,N-dimethyl-4-[[2-(1-methylpyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl]amino]benzamide
Show/Hide
|
C20H19ClN6O
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0019341
|
N,N-dimethyl-4-[[2-(1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl]amino]benzenesulfonamide
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|
C18H18N6O2S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0322506
|
US10479788, Example 65
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|
C22H25N7O
|
3
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
IC50 = 370 nM
|
|
|
| 3 |
Ki = 3.7 nM
|
|
|
|
CP0020306
|
N-[2-chloro-4-(1-methylpyrazol-4-yl)phenyl]-2-(1-methylpyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C21H18ClN7
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0416442
|
US10479788, Example 68
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|
C23H27N7O
|
3
|
| 1 |
IC50 = 18 nM
|
|
|
| 2 |
IC50 = 45 nM
|
|
|
| 3 |
Ki = 0.5 nM
|
|
|
|
CP0464249
|
US10479788, Example 34
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|
C24H20N6O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0030810
|
tert-butyl 6-[2-chloro-4-(1,3-oxazol-5-yl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C25H23ClN6O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0020468
|
tert-butyl 6-[2-chloro-4-(1-methylpyrazol-3-yl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C26H26ClN7O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0026786
|
[3-chloro-4-[[2-(1-methylpyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl]amino]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanone
Show/Hide
|
C25H28ClN7O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0030350
|
N-(2-chloro-4-methoxyphenyl)-2-(1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C17H14ClN5O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0282308
|
N-[2-methoxy-4-(1-methylpiperidin-4-yl)oxyphenyl]-4-(1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine
Show/Hide
|
C24H26N6O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0024475
|
tert-butyl 6-(2-chloro-4-pyrimidin-5-ylanilino)-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C26H24ClN7O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0024756
|
2-(1H-pyrazol-4-yl)-N-[4-(pyrazol-1-ylmethyl)phenyl]-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C20H17N7
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0023441
|
tert-butyl 6-[2-chloro-4-(dimethylcarbamoyl)anilino]-2-(1,3-oxazol-5-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C24H24ClN5O4
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0409723
|
US10479788, Example 76
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|
C24H29N7O
|
3
|
| 1 |
IC50 = 22 nM
|
|
|
| 2 |
IC50 = 420 nM
|
|
|
| 3 |
Ki = 4.2 nM
|
|
|
|
CP0016119
|
3-methoxy-N,N-dimethyl-4-[[2-(1-methylpyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl]amino]benzamide
Show/Hide
|
C21H22N6O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0510841
|
US11046688, Example 95
Show/Hide
|
C22H20N8
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0016086
|
N-(2-methoxyphenyl)-2-(1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C17H15N5O
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0033200
|
N-(3,4-dimethoxyphenyl)-2-(1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C18H17N5O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0023727
|
N-(2-methoxyphenyl)-2-(1,3-oxazol-5-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C17H14N4O2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0033199
|
3-chloro-N,N-dimethyl-4-[[2-(1-methylpyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-yl]amino]benzenesulfonamide
Show/Hide
|
C19H19ClN6O2S
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0019340
|
N-(2-chlorophenyl)-2-(1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C16H12ClN5
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0022007
|
tert-butyl 6-(2-chloro-4-pyridin-3-ylanilino)-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C27H25ClN6O2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0016088
|
tert-butyl 6-(2-chloro-4-pyrazin-2-ylanilino)-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C26H24ClN7O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0380191
|
N-(2,4-dimethoxyphenyl)-8-(1-methylpyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine
Show/Hide
|
C19H18N6O2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0473508
|
US10479788, Example 70
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|
C25H29N7O
|
2
|
| 1 |
IC50 = 46 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0322591
|
US11046688, Example 97
Show/Hide
|
C24H24N8O
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0016120
|
N-(4-methoxyphenyl)-2-(1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C17H15N5O
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0023704
|
N-(2-ethoxyphenyl)-2-(1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C18H17N5O
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0409722
|
US10479788, Example 38
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|
C22H25N7O
|
2
|
| 1 |
IC50 = 62 nM
|
|
|
| 2 |
IC50 > 1000 nM
|
|
|
|
CP0024755
|
N-[4-(2-morpholin-4-ylethoxy)phenyl]-2-(1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C22H24N6O2
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0020250
|
tert-butyl 6-(2-chloroanilino)-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C22H22ClN5O2
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0030348
|
N-(2-chlorophenyl)-2-(1-methylpyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C17H14ClN5
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0023429
|
N-(2-methoxyphenyl)-2-[1-(2,2,2-trifluoroethyl)pyrazol-4-yl]-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C19H16F3N5O
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0022008
|
tert-butyl 6-[2-chloro-4-(dimethylsulfamoyl)anilino]-2-(1-methylpyrazol-4-yl)pyrrolo[3,2-c]pyridine-1-carboxylate
Show/Hide
|
C24H27ClN6O4S
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0218744
|
US11046688, Example 30
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|
C21H20N4O2
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0509105
|
US10479788, Example 35
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|
C21H20N6O
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0026785
|
N-(2-methoxyphenyl)-2-(1-methylpyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C18H17N5O
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0452275
|
N-(4-methoxyphenyl)-8-(1-methylpyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine
Show/Hide
|
C18H16N6O
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0558078
|
US11046688, Example 98
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|
C24H24N8O2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0510840
|
US11046688, Example 53
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|
C22H22N6O2
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0329775
|
US11046688, Example 90
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|
C24H26N6OS
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0020467
|
2-[1-(difluoromethyl)pyrazol-4-yl]-N-(2-methoxyphenyl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C18H15F2N5O
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0030349
|
N-(2-methoxyphenyl)-2-(3-methylimidazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C18H17N5O
|
1
|
| 1 |
IC50 = 640 nM
|
|
|
|
CP0380190
|
US11046688, Example 28
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|
C20H18N4O
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
|
CP0574197
|
4-(furan-3-yl)-3-phenyl-1H-pyrazolo[4,3-c]pyridine
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|
C16H11N3O
|
1
|
| 1 |
IC50 = 810 nM
|
|
|
|
CP0023724
|
N-(2,4-dimethoxyphenyl)-2-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C20H18F3N5O2
|
1
|
| 1 |
IC50 = 990 nM
|
|
|
|
CP0027503
|
2-(1,5-dimethylpyrazol-4-yl)-N-(2-methoxyphenyl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C19H19N5O
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0574196
|
US11046688, Example 27
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|
C20H16N2O2
|
1
|
| 1 |
IC50 = 3660 nM
|
|
|
|
CP0022918
|
N-[2-methoxy-5-(trifluoromethyl)phenyl]-2-(1-methylpyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C19H16F3N5O
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0023435
|
2-(3,5-dimethyl-1,2-oxazol-4-yl)-N-(2-methoxyphenyl)-1H-pyrrolo[3,2-c]pyridin-6-amine
Show/Hide
|
C19H18N4O2
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
