3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(6-chloroquinolin-3-yl)propanamide

2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-5-(2-methyloctan-2-yl)phenol

3-(4-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-8-(trifluoromethyl)quinoline

1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide

N-[4-chloro-3-(furan-2-yl)phenyl]-2-(4-chlorophenyl)sulfonyl-2-methylpropanamide

3-(4-(3-(3-chloropyridin-4-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)quinoline

3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(5-(piperidin-1-yl)-1,3,4-thiadiazol-2-yl)propanamide

6-Chloro-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propyl)quinolin-3-amine

2-(4-chlorophenylsulfonyl)-2-methyl-N-(5-(5-methylthiophen-2-yl)pyridin-3-yl)propanamide

3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(quinolin-3-yl)propanamide

3-(4-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-6-(trifluoromethoxy)quinoline

N-[3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propyl]quinolin-6-amine

N-[3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propyl]quinolin-3-amine

1-[4-[8-(2-Chlorophenyl)-9-(2-methoxyethyl)-2-methylpurin-6-yl]piperazin-1-yl]ethanone Hydrochloride

3-(4-(3-cyclohexyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)quinoline

2-tert-Butyl-5-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propoxy)pyrimidine

5-tert-Butyl-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propyl)isoxazol-3-amine

3-(3-(2-Cyano-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(9-ethyl-9H-carbazol-3-yl)propanamide

2-methyl-N-(quinolin-3-yl)-2-(4-(trifluoromethyl)phenylsulfonyl)propanamide

3-(4-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-8,8-dimethyl-5,6,7,8-tetrahydroquinoline

3-(4-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)butyl)quinoline

3-(4-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-5,6,7,8-tetrahydroquinoline

8-(2-Chlorophenyl)-6-(4-ethylpiperazin-1-yl)-2,9-dimethyl-purine Hydrochloride

3-(4-(3-(2,4-dichlorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)quinoline

6-Chloro-3-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propoxy)quinoline

N-[3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propyl]-3-(trifluoromethoxy)quinolin-6-amine

N-(9-ethylcarbazol-3-yl)-3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide

3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(9-ethyl-9H-carbazol-3-yl)propanamide

3-((S)-3-((3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)methyl)pyrrolidin-1-yl)quinoline

N-[4-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-2-methylbutan-2-yl]quinolin-3-amine

5-(3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propylamino)-2-(2,2,2-trifluoroethoxy)nicotinonitrile

1-butyl-2-[(4-ethoxyphenyl)methyl]-N,N-diethylbenzimidazole-5-carboxamide

8-(2-chlorophenyl)-6-(4-ethylpiperazin-1-yl)-9-(3-methoxypropyl)-2-methylpurine

N-(9-ethylcarbazol-3-yl)-3-[3-(4-fluoro-2-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide

6-chloro-3-(4-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)quinoline

8-(2-Chlorophenyl)-6-(4-ethylpiperazin-1-yl)-2-methyl-9Hpurine Hydrochloride

(+/-) N-(4-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)butan-2-yl)quinolin-3-amine

2-(2-chloro-4-(trifluoromethyl)phenylsulfonyl)-2-methyl-N-(quinolin-3-yl)propanamide

N-(5-tert-butyl-1,2-oxazol-3-yl)-3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide

2-(4-chlorophenylsulfonyl)-2-methyl-N-(5-o-tolyl-1,3,4-thiadiazol-2-yl)propanamide

2-(4-chlorophenylsulfonyl)-2-methyl-N-(quinolin-3-yl)propanamide

3-((R)-3-((3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)methyl)pyrrolidin-1-yl)quinoline

3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(6-(trifluoromethoxy)benzo[d]thiazol-2-yl)propanamide

N-(5-tert-butyl-1,2-oxazol-3-yl)-2-(4-chlorophenyl)sulfonyl-2-methylpropanamide

3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(4-isopropylphenyl)propanamide

(+/-)-N-((1R,2R)-2-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)cyclopentyl)quinolin-3-amine

3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(6-chloro-1,8-naphthyridin-3-yl)propanamide

3-(4-(3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)quinoline

2-(4-fluorophenylsulfonyl)-2-methyl-N-(quinolin-3-yl)propanamide

3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(6-(trifluoromethyl)pyridin-3-yl)propanamide

8-(3-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-tetrahydropyran-4-yl-purine Hydrochloride

3-(4-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)quinoline

2-(4-ethoxybenzyl)-N,N-diethyl-1-isopentyl-1H-benzo[d]imidazole-5-carboxamide

6-Chloro-N-(3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propyl)benzo[d]thiazol-2-amine

N-[2-[8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9H-purin-9-yl]ethyl]acetamide Hydrochloride

N-[2-[8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)purin-9-yl]ethyl]acetamide

2-[8-(2-chlorophenyl)-9-(2-methoxyethyl)-2-methylpurin-6-yl]-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-6-one;hydrochloride

2-[8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)purin-9-yl]-2-methylpropan-1-ol

8-(2-Fluorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-tetrahydropyran-4-yl-purine Hydrochloride

2-[8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-purin-9-yl]ethanol Hydrochloride

2-[8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)purin-9-yl]ethanol

1-[10-[10-[5-(diethylcarbamoyl)-2-[(4-ethoxyphenyl)methyl]benzimidazol-1-yl]decyl-methylamino]decyl]-2-[(4-ethoxyphenyl)methyl]-N,N-diethylbenzimidazole-5-carboxamide

2-(4-chlorophenylsulfonyl)-2-methyl-N-(5-(3-methyl-tetrahydrofuran-3-yl)-1,3,4-thiadiazol-2-yl)propanamide

2-(2-chloro-4-fluorophenylsulfonyl)-2-methyl-N-(quinolin-3-yl)propanamide

N-[(3-chloro-4-fluorophenyl)methyl]-2-(4-chlorophenyl)sulfonyl-2-methylpropanamide

2-(4-chlorophenyl)sulfonyl-N-[4-chloro-2-(trifluoromethoxy)phenyl]-2-methylpropanamide

2-(4-chlorophenylsulfonyl)-2-methyl-N-(5-methylisoxazol-3-yl)propanamide

N-(3-bromo-4-chlorophenyl)-2-(4-chlorophenyl)sulfonyl-2-methylpropanamide

N-benzyl-2-(4-chlorophenyl)sulfonyl-2-methylpropanamide

N-(4-chloro-2-cyanophenyl)-2-(4-chlorophenyl)sulfonyl-2-methylpropanamide

2-(4-chlorophenylsulfonyl)-2-methyl-N-(4-(trifluoromethyl)phenyl)propanamide

2-(4-chlorophenylsulfonyl)-2-methyl-N-(5-methylthiazol-2-yl)propanamide

2-(2-chloro-4-methoxyphenylsulfonyl)-2-methyl-N-(quinolin-3-yl)propanamide

2-(4-chlorophenylsulfonyl)-2-methyl-N-(3-(trifluoromethyl)phenyl)propanamide

N-(9-ethylcarbazol-3-yl)-3-[3-(2-fluorophenyl)-1,2-oxazol-5-yl]propanamide

N-(9-ethylcarbazol-3-yl)-3-[3-(2-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide

3-(3-(3-Chlorophenyl)-1,2,4-oxadiazol-5-yl)-N-(9-ethyl-9H-carbazol-3-yl)propanamide

N-(9-ethylcarbazol-3-yl)-3-[3-(2-propan-2-ylphenyl)-1,2,4-oxadiazol-5-yl]propanamide

N-(9-ethylcarbazol-3-yl)-3-[4-(2-fluorophenyl)-1,3-oxazol-2-yl]propanamide

N-(2-tert-butylpyrimidin-5-yl)-3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propanamide

3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(5-cyano-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)propanamide

3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(4-(trifluoromethyl)phenyl)propanamide

3-(3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl)-N-(9-ethyl-9H-carbazol-3-yl)propanamide

N-(9-ethylcarbazol-3-yl)-3-[3-(oxan-4-yl)-1,2,4-oxadiazol-5-yl]propanamide

N-(9-ethylcarbazol-3-yl)-3-[5-(2-fluorophenyl)tetrazol-2-yl]propanamide

3-(3-(3-Cyanopyridin-4-yl)-1,2,4-oxadiazol-5-yl)-N-(9-ethyl-9Hcarbazol-3-yl)propanamide

N-(9-ethylcarbazol-3-yl)-3-[5-(2-fluorophenyl)-1-methylpyrazol-3-yl]propanamide

N-(9-ethylcarbazol-3-yl)-3-[3-(2-fluorophenyl)-1H-pyrazol-5-yl]propanamide

N-(9-ethylcarbazol-3-yl)-3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]propanamide

3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[3-chloro-4-(trifluoromethyl)phenyl]propanamide

N-(9-ethylcarbazol-3-yl)-3-[4-(2-fluorophenyl)triazol-1-yl]propanamide

3-[3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-[2-chloro-4-(trifluoromethyl)phenyl]propanamide

8-(2-Methoxyphenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-tetrahydropyran-4-yl-purine Hydrochloride

8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-(2-methylsulfonylethyl)purine Hydrochloride

2-Methyl-6-(4-methylpiperazin-1-yl)-9-tetrahydropyran-4-yl-8-[3-(trifluoromethyl)phenyl]purine Hydrochloride

2-[(4-ethoxyphenyl)methyl]-N-[3-[3-[[2-[(4-ethoxyphenyl)methyl]-1-(3-methylbutyl)benzimidazole-5-carbonyl]amino]propyl-methylamino]propyl]-1-(3-methylbutyl)benzimidazole-5-carboxamide

8-(3-Methoxyphenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-tetrahydropyran-4-yl-purine Hydrochloride

N-[10-(dimethylamino)decyl]-2-[(4-ethoxyphenyl)methyl]-1-(3-methylbutyl)benzimidazole-5-carboxamide

1-[10-(dimethylamino)decyl]-2-[(4-ethoxyphenyl)methyl]-N,N-diethylbenzimidazole-5-carboxamide

2-[(4-ethoxyphenyl)methyl]-N-[10-[10-[[2-[(4-ethoxyphenyl)methyl]-1-(3-methylbutyl)benzimidazole-5-carbonyl]amino]decyl-methylamino]decyl]-1-(3-methylbutyl)benzimidazole-5-carboxamide

1-[3-[3-[5-(diethylcarbamoyl)-2-[(4-ethoxyphenyl)methyl]benzimidazol-1-yl]propyl-methylamino]propyl]-2-[(4-ethoxyphenyl)methyl]-N,N-diethylbenzimidazole-5-carboxamide

8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-[(3S)-tetrahydrofuran-3-yl]purine Hydrochloride

1-[2-[8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9H-purin-9-yl]ethyl]pyrrolidin-2-one Hydrochloride

2-Methyl-6-(4-methylpiperazin-1-yl)-8-(o-tolyl)-9-tetrahydropyran-4-yl-purine Hydrochloride

2-Methyl-6-(4-methylpiperazin-1-yl)-9-tetrahydropyran-4-yl-8-[2-(trifluoromethyl)phenyl]purine Hydrochloride

8-(2-Ethylphenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-tetrahydropyran-4-yl-purine Hydrochloride

8-(2-Chlorophenyl)-6-(4-ethylpiperazin-1-yl)-2-methyl-9-(tetrahydropyran-4-ylmethyl)purine Hydrochloride

8-(2-Chlorophenyl)-9-cyclopropyl-2-methyl-6-(4-methylpiperazin-1-yl)purine Hydrochloride

8-(2-Chlorophenyl)-6-(4-ethylpiperazin-1-yl)-9-(2-methoxyethyl)-2-methyl-purine Hydrochloride

8-(2-Cyclopropylphenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-tetrahydropyran-4-yl-purine Hydrochloride

8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-tetrahydropyran-4-yl-purine Hydrochloride

8-(4-Methoxy-2-methyl-phenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-tetrahydropyran-4-yl-purine Hydrochloride

8-(2-Chlorophenyl)-6-[4-(2-fluoroethyl)piperazin-1-yl]-9-(2-methoxyethyl)-2-methyl-purine Hydrochloride

8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-[(3R)-tetrahydrofuran-3-yl]purine Hydrochloride

(2R)-2-[8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)purin-9-yl]propan-1-ol

8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-(oxan-4-yl)purine

8-(2-chlorophenyl)-9-(1,3-dimethoxypropan-2-yl)-6-(4-ethylpiperazin-1-yl)-2-methylpurine

8-(2-chlorophenyl)-6-(4-ethylpiperazin-1-yl)-9-(2-methoxyethyl)-2-methylpurine

methyl N-[2-[8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)purin-9-yl]ethyl]carbamate

(2S)-2-[8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)purin-9-yl]propan-1-ol

1-[8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)purin-9-yl]-2-methylpropan-2-ol

N-[1-[6-(3-chloropyridin-4-yl)-5-[4-(trifluoromethyl)phenyl]pyrazin-2-yl]piperidin-4-yl]-2-methylpropanamide

5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide

1-(6-(2-chloropyridin-4-yl)-5-(4-(trifluoromethyl)phenyl)pyrazin-2-yl)-3-(ethylamino)azetidine-3-carboxamide

4-[6-(3-Chloro-pyridin-4-yl)-5-(4-trifluoromethyl-phenyl)-pyrazin-2-yl]-thiomorpholine 1,1-dioxide

1-(5-(4-chlorophenyl)-6-(2-chloropyridin-4-yl)pyrazin-2-yl)-4-(ethylamino)piperidine-4-carboxamide

N-[1-[6-(3-chloropyridin-4-yl)-5-[4-(trifluoromethyl)phenyl]pyrazin-2-yl]piperidin-4-yl]propanamide

1-(6-(2-chloropyridin-4-yl)-5-(4-(trifluoromethyl)phenyl)pyrazin-2-yl)-4-(ethylamino)piperidine-4-carboxamide

1-(5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)pyrazin-2-yl)-4-(ethylamino)piperidine-4-carboxamide

[1-(cyclohexylmethyl)-7-methoxyindol-3-yl]-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]methanone

(S)-1-{[1-(cyclohexyl)methyl-7-methoxy-1Hindol-3-yl]carbonyl}-3,4-dimethylpiperazine hydrochloride salt

(1-(cyclohexylmethyl)-7-methoxy-1H-indol-3-yl)((3S,5R)-3,4,5-trimethylpiperazin-1-yl)methanone hydrochloride

((R)-3-cyclohexyl-2,3-dihydro-[1,4]oxazino[2,3,4-hi]indol-6-yl)((S)-dihydro-1H-pyrido[1,2-a]pyrazin-2(6H,7H,8H,9H,9aH)-yl)methanone

1-(6-(2-chlorophenyl)-5-(4-chlorophenyl)pyrazin-2-yl)-4-(ethylamino)piperidine-4-carboxamide

1-(6-(2,4-dichlorophenyl)-5-(4-fluorophenyl)pyrazin-2-yl)-4-(ethylamino)piperidine-4-carboxamide

N-[1-[6-(3-chloropyridin-4-yl)-5-[4-(trifluoromethyl)phenyl]pyrazin-2-yl]piperidin-4-yl]acetamide

[(11R)-11-cyclohexyl-9-oxa-1-azatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraen-3-yl]-[(3S)-3,4-dimethylpiperazin-1-yl]methanone

(S)-(1-(cyclohexylmethyl)-7-methoxy-1H-indol-3-yl)(dihydro-1H-pyrido[1,2-a]pyrazin-2(6H,7H,8H,9H,9aH)-yl)methanone

1-(5,6-bis(4-ethoxyphenyl)pyrazin-2-yl)-4-(ethylamino)piperidine-4-carboxamide

2-[[3-[7-chloro-1-(oxan-4-ylmethyl)indol-3-yl]-1,2,4-oxadiazol-5-yl]methyl-methylamino]acetamide

1-(5-(4-chlorophenyl)-6-(pyridin-4-yl)pyrazin-2-yl)-4-(ethylamino)piperidine-4-carboxamide

[(11R)-11-cyclohexyl-9-oxa-1-azatricyclo[6.3.1.04,12]dodeca-2,4(12),5,7-tetraen-3-yl]-(4-ethylpiperazin-1-yl)methanone

(11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphthalen-1-ylcarbonyl)-9-oxa-1-azatricyclo[6.3.1.0^{4,12}]dodeca-2,4(12),5,7-tetraene

1-(6-(2-chlorophenyl)-5-(4-ethoxyphenyl)pyrazin-2-yl)-4-(ethylamino)piperidine-4-carboxamide

1-(5-(4-chlorophenyl)-6-(4-cyanophenyl)pyrazin-2-yl)-4-(ethylamino)piperidine-4-carboxamide