| Compound ID |
Compound Name |
Compound Formula |
|
CP0443467
|
9-(2,6-difluorobenzoyl)-N-[4-(trifluoromethoxy)phenyl]-2,9-diazaspiro[5.5]undecane-2-carboxamide
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|
C24H24F5N3O3
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0175259
|
8-(2-fluoro-5-hydroxybenzoyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C23H23F4N3O4
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0149641
|
8-(2,6-difluorobenzoyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C23H22F5N3O3
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0339347
|
N-[4-(trifluoromethoxy)phenyl]-8-[1-(trifluoromethyl)cyclopropanecarbonyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C21H23F6N3O3
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0175589
|
8-(2-chlorobenzoyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C23H23ClF3N3O3
|
1
|
| 1 |
IC50 = 5.2 nM
|
|
|
|
CP0147504
|
8-(5-methyl-1,2-oxazole-3-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C21H23F3N4O4
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0147507
|
8-(2-fluorobenzoyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C23H23F4N3O3
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0149634
|
8-(2,6-difluorobenzoyl)-N-[4-(trifluoromethyl)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C23H22F5N3O2
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0339320
|
8-(2-cyclopropylacetyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C21H26F3N3O3
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0175585
|
8-(quinoline-5-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C26H25F3N4O3
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0434199
|
9-(2-acetamidobenzoyl)-N-[4-(trifluoromethyl)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C25H27F3N4O4
|
1
|
| 1 |
IC50 = 6.8 nM
|
|
|
|
CP0430056
|
9-(5-methylpyrazine-2-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C22H24F3N5O4
|
1
|
| 1 |
IC50 = 8.8 nM
|
|
|
|
CP0339348
|
8-(cyclohexanecarbonyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C23H30F3N3O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0431714
|
9-(2-fluorobenzoyl)-N-[4-(trifluoromethoxy)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C23H23F4N3O4
|
1
|
| 1 |
IC50 = 9.3 nM
|
|
|
|
CP0339289
|
8-(2,2-dimethylpropanoyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C21H28F3N3O3
|
1
|
| 1 |
IC50 = 9.4 nM
|
|
|
|
CP0147503
|
8-(furan-2-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C21H22F3N3O4
|
1
|
| 1 |
IC50 = 9.5 nM
|
|
|
|
CP0439867
|
9-(4-chloropyridine-2-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C22H22ClF3N4O4
|
1
|
| 1 |
IC50 = 11.6 nM
|
|
|
|
CP0339322
|
8-(5-cyclopropyl-1,2-oxazole-4-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C23H25F3N4O4
|
1
|
| 1 |
IC50 = 11.7 nM
|
|
|
|
CP0339293
|
8-(5-methylpyrazine-2-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C22H24F3N5O3
|
1
|
| 1 |
IC50 = 11.9 nM
|
|
|
|
CP0421093
|
9-(2,2-dimethylpropanoyl)-N-[4-(trifluoromethyl)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C21H28F3N3O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0074784
|
8-(2-methylcyclopropanecarbonyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C21H26F3N3O3
|
1
|
| 1 |
IC50 = 12.9 nM
|
|
|
|
CP0431716
|
9-(2-chlorobenzoyl)-N-[4-(trifluoromethyl)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C23H23ClF3N3O3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0471434
|
9-(cyclohexanecarbonyl)-N-[4-(trifluoromethoxy)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C23H30F3N3O4
|
1
|
| 1 |
IC50 = 14.5 nM
|
|
|
|
CP0430058
|
9-(4-cyanobenzoyl)-N-[4-(trifluoromethyl)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C24H23F3N4O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0339288
|
8-(2,2-difluorocyclopropanecarbonyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C20H22F5N3O3
|
1
|
| 1 |
IC50 = 15.8 nM
|
|
|
|
CP0443468
|
9-(2,6-difluorobenzoyl)-N-[4-(trifluoromethoxy)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C23H22F5N3O4
|
1
|
| 1 |
IC50 = 18.5 nM
|
|
|
|
CP0439869
|
9-(2,6-difluorobenzoyl)-N-[4-(trifluoromethyl)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
Show/Hide
|
C23H22F5N3O3
|
1
|
| 1 |
IC50 = 19.1 nM
|
|
|
|
CP0175591
|
8-(1H-benzimidazole-4-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C24H24F3N5O3
|
1
|
| 1 |
IC50 = 22.2 nM
|
|
|
|
CP0467266
|
9-(5-cyclopropyl-1,2-oxazole-4-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
Show/Hide
|
C23H25F3N4O5
|
1
|
| 1 |
IC50 = 22.2 nM
|
|
|
|
CP0224939
|
8-(4-hydroxycyclohexanecarbonyl)-N-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decane-2-carboxamide
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|
C23H30F3N3O4
|
1
|
| 1 |
IC50 = 22.4 nM
|
|
|
|
CP0421106
|
9-(4-chlorobenzoyl)-N-[4-(trifluoromethyl)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C23H23ClF3N3O3
|
1
|
| 1 |
IC50 = 24.9 nM
|
|
|
|
CP0439868
|
9-(5-methyl-1,2-oxazole-3-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
Show/Hide
|
C21H23F3N4O5
|
1
|
| 1 |
IC50 = 25.7 nM
|
|
|
|
CP0430055
|
9-(1-phenylcyclopropanecarbonyl)-N-[4-(trifluoromethoxy)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C26H28F3N3O4
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0390071
|
9-(2-cyclopropylacetyl)-N-[4-(trifluoromethyl)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C21H26F3N3O3
|
1
|
| 1 |
IC50 = 31.4 nM
|
|
|
|
CP0390073
|
9-(3-chlorobenzoyl)-N-[4-(trifluoromethyl)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C23H23ClF3N3O3
|
1
|
| 1 |
IC50 = 36.9 nM
|
|
|
|
CP0421089
|
9-[2-(2-methoxyphenyl)acetyl]-N-[4-(trifluoromethoxy)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C25H28F3N3O5
|
1
|
| 1 |
IC50 = 71.6 nM
|
|
|
|
CP0421091
|
9-(5-cyclopropyl-1H-pyrazole-4-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C23H26F3N5O4
|
1
|
| 1 |
IC50 = 96.9 nM
|
|
|
|
CP0430054
|
9-(2-pyridin-2-ylacetyl)-N-[4-(trifluoromethoxy)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C23H25F3N4O4
|
1
|
| 1 |
IC50 > 20 nM
|
|
|
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CP0431713
|
9-(2-oxo-1,3-dihydroindole-5-carbonyl)-N-[4-(trifluoromethoxy)phenyl]-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxamide
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|
C25H25F3N4O5
|
1
|
| 1 |
IC50 > 20 nM
|
|
|
