| Compound ID |
Compound Name |
Compound Formula |
|
CP0517645
|
3-[[4-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-1,3-thiazol-2-yl]amino]benzoic acid
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|
C19H20N4O3S2
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0466727
|
N-[4-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]prop-2-enamide
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|
C12H12N4O2S2
|
3
|
| 1 |
IC50 = 140 nM
|
|
|
| 2 |
IC50 = 570 nM
|
|
|
| 3 |
IC50 = 2160 nM
|
|
|
|
CP0109622
|
4-[[[6-[1-(cyclopropylmethyl)-2-oxopyridin-4-yl]-1,3-benzothiazol-2-yl]amino]methyl]cyclohexane-1-carboxylic acid
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|
C24H27N3O3S
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0058429
|
1-(cyclopropylmethyl)-4-[2-[[(1R)-1-(oxan-4-yl)ethyl]amino]-1,3-benzothiazol-6-yl]pyridin-2-one
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|
C23H27N3O2S
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0058431
|
6-[6-(methoxymethyl)pyridin-3-yl]-1,3-benzothiazol-2-amine
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|
C14H13N3OS
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0058995
|
4-(2-amino-1,3-benzothiazol-6-yl)-1-ethylpyridin-2-one
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|
C14H13N3OS
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0071821
|
4-(2-amino-1,3-benzothiazol-6-yl)-1-methylpyridin-2-one
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|
C13H11N3OS
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0066812
|
1-(cyclopropylmethyl)-4-[2-(oxan-4-ylmethylamino)-1,3-benzothiazol-6-yl]pyridin-2-one
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|
C22H25N3O2S
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0059000
|
6-(6-methylpyridin-3-yl)-1,3-benzothiazol-2-amine
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|
C13H11N3S
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0066807
|
6-phenyl-1,3-benzothiazol-2-amine
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|
C13H10N2S
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0141572
|
2-[5-(2-amino-1,3-benzothiazol-6-yl)pyridin-2-yl]oxyethanol
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|
C14H13N3O2S
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0491667
|
N-[5-[2-[3-acetyl-N-(2-hydroxyethyl)anilino]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]acetamide
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|
C19H20N4O3S2
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0058998
|
1-(cyclopropylmethyl)-4-[2-[(1,1-dioxothian-4-yl)methylamino]-1,3-benzothiazol-6-yl]pyridin-2-one
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|
C22H25N3O3S2
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0066763
|
6-(6-ethylsulfanylpyridin-3-yl)-1,3-benzothiazol-2-amine
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|
C14H13N3S2
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0066814
|
4-(2-amino-1,3-benzothiazol-6-yl)-1H-pyridin-2-one
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|
C12H9N3OS
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0071820
|
6-(6-ethoxypyridin-3-yl)-1,3-benzothiazol-2-amine
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|
C14H13N3OS
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0072106
|
6-pyridin-3-yl-1,3-benzothiazol-2-amine
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|
C12H9N3S
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0445795
|
N-[5-[2-(2-hydroxyethylamino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
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|
C14H20N4O2S2
|
1
|
| 1 |
IC50 = 730 nM
|
|
|
|
CP0071824
|
[5-(2-amino-1,3-benzothiazol-6-yl)pyridin-2-yl]methanol
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|
C13H11N3OS
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0177911
|
6-(1-benzylpyrazol-4-yl)-1,3-benzothiazol-2-amine
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|
C17H14N4S
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0038494
|
6-(6-methoxypyridin-3-yl)benzo[d]thiazol-2-amine
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|
C13H11N3OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0059004
|
6-(pyridin-4-yl)benzo[d]thiazol-2-amine
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|
C12H9N3S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0066804
|
6-[6-(ethylamino)pyridin-3-yl]-1,3-benzothiazol-2-amine
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|
C14H14N4S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0066806
|
6-(5-propan-2-yloxypyridin-3-yl)-1,3-benzothiazol-2-amine
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|
C15H15N3OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0141585
|
6-(2-methylpyrazol-3-yl)-1,3-benzothiazol-2-amine
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|
C11H10N4S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0155758
|
6-[6-(2-methoxyethoxy)pyridin-3-yl]-1,3-benzothiazol-2-amine
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|
C15H15N3O2S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0141586
|
6-(1-methylpyrazol-4-yl)-1,3-benzothiazol-2-amine
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|
C11H10N4S
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0175247
|
6-(1-methylpyrazol-3-yl)-1,3-benzothiazol-2-amine
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|
C11H10N4S
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0178134
|
6-(6-propan-2-yloxypyridin-3-yl)-1,3-benzothiazol-2-amine
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|
C15H15N3OS
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0477125
|
tert-butyl N-[5-[2-(2-hydroxyethylamino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]carbamate
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|
C14H20N4O3S2
|
1
|
| 1 |
IC50 = 1360 nM
|
|
|
|
CP0491668
|
N-[5-[2-(2-hydroxyethylamino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]benzamide
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|
C16H16N4O2S2
|
1
|
| 1 |
IC50 = 1540 nM
|
|
|
|
CP0058999
|
6-[6-[ethyl(methyl)amino]pyridin-3-yl]-1,3-benzothiazol-2-amine
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|
C15H16N4S
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0065579
|
6-(1-ethylpyrazol-4-yl)-1,3-benzothiazol-2-amine
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|
C12H12N4S
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0065581
|
6-[6-(trifluoromethyl)pyridin-3-yl]-1,3-benzothiazol-2-amine
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|
C13H8F3N3S
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0071822
|
4-(2-amino-1,3-benzothiazol-6-yl)-1-(cyclopropylmethyl)pyridin-2-one
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|
C16H15N3OS
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0481790
|
N-[4-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]-2-bromoacetamide
Show/Hide
|
C11H11BrN4O2S2
|
3
|
| 1 |
IC50 = 1670 nM
|
|
|
| 2 |
IC50 = 1710 nM
|
|
|
| 3 |
IC50 = 2110 nM
|
|
|
|
CP0059006
|
6-(1-cyclopropylpyrazol-4-yl)-1,3-benzothiazol-2-amine
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|
C13H12N4S
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0072116
|
6-[1-(cyclopropylmethyl)pyrazol-4-yl]-1,3-benzothiazol-2-amine
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|
C14H14N4S
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0141588
|
6-(1-propylpyrazol-4-yl)-1,3-benzothiazol-2-amine
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|
C13H14N4S
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0445794
|
N-[5-[2-[3-acetyl-N-(2-hydroxyethyl)anilino]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
Show/Hide
|
C22H26N4O3S2
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0058996
|
1-(cyclopropylmethyl)-4-[2-[[(1S)-1-(oxan-4-yl)ethyl]amino]-1,3-benzothiazol-6-yl]pyridin-2-one
Show/Hide
|
C23H27N3O2S
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
|
CP0059003
|
6-pyridin-2-yl-1,3-benzothiazol-2-amine
Show/Hide
|
C12H9N3S
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
|
CP0066809
|
6-(1-propan-2-ylpyrazol-4-yl)-1,3-benzothiazol-2-amine
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|
C13H14N4S
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
|
CP0154374
|
5-(2-amino-1,3-benzothiazol-6-yl)-N-methylpyridine-2-carboxamide
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|
C14H12N4OS
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
|
CP0068463
|
6-[6-(methylaminomethyl)pyridin-3-yl]-1,3-benzothiazol-2-amine
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|
C14H14N4S
|
1
|
| 1 |
IC50 = 3162.28 nM
|
|
|
|
CP0445796
|
N-[5-[2-[cyclohexyl(2-hydroxyethyl)amino]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
Show/Hide
|
C20H30N4O2S2
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0058993
|
5-(2-amino-1,3-benzothiazol-6-yl)-1H-pyridin-2-one
Show/Hide
|
C12H9N3OS
|
1
|
| 1 |
IC50 = 3981.07 nM
|
|
|
|
CP0059002
|
6-(5-methylsulfonylpyridin-3-yl)-1,3-benzothiazol-2-amine
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|
C13H11N3O2S2
|
1
|
| 1 |
IC50 = 3981.07 nM
|
|
|
|
CP0477148
|
N-[5-[2-(2-hydroxyethylamino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]acetamide
Show/Hide
|
C11H14N4O2S2
|
1
|
| 1 |
IC50 = 4500 nM
|
|
|
|
CP0402074
|
(E)-N-[4-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]-4-methylpent-2-enamide
Show/Hide
|
C15H18N4O2S2
|
3
|
| 1 |
IC50 = 4840 nM
|
|
|
| 2 |
IC50 = 5580 nM
|
|
|
| 3 |
IC50 = 17400 nM
|
|
|
|
CP0450706
|
N-[4-(2-acetamido-4-methyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]propanamide
Show/Hide
|
C12H14N4O2S2
|
3
|
| 1 |
IC50 = 5210 nM
|
|
|
| 2 |
IC50 = 5390 nM
|
|
|
| 3 |
IC50 = 5580 nM
|
|
|
|
CP0550889
|
3-[[4-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-1,3-thiazol-2-yl]amino]propanoic acid
Show/Hide
|
C15H20N4O3S2
|
1
|
| 1 |
IC50 = 5460 nM
|
|
|
|
CP0532475
|
N-[5-[2-[cyclohexyl(2-hydroxyethyl)amino]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]acetamide
Show/Hide
|
C17H24N4O2S2
|
1
|
| 1 |
IC50 = 5800 nM
|
|
|
|
CP0058990
|
6-pyrimidin-2-yl-1,3-benzothiazol-2-amine
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|
C11H8N4S
|
1
|
| 1 |
IC50 = 6309.57 nM
|
|
|
|
CP0058991
|
6-pyrazin-2-yl-1,3-benzothiazol-2-amine
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|
C11H8N4S
|
1
|
| 1 |
IC50 = 6309.57 nM
|
|
|
|
CP0567437
|
4-[[4-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-1,3-thiazol-2-yl]amino]butanoic acid
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|
C16H22N4O3S2
|
1
|
| 1 |
IC50 = 6980 nM
|
|
|
|
CP0141584
|
6-(6-methylsulfonylpyridin-3-yl)-1,3-benzothiazol-2-amine
Show/Hide
|
C13H11N3O2S2
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0445894
|
N-[5-[2-(cyclohexylamino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]acetamide
Show/Hide
|
C15H20N4OS2
|
1
|
| 1 |
IC50 = 8290 nM
|
|
|
|
CP0458180
|
N-[5-[2-[cyclohexyl(methyl)amino]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]acetamide
Show/Hide
|
C16H22N4OS2
|
1
|
| 1 |
IC50 = 9520 nM
|
|
|
|
CP0445797
|
2-[[4-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-1,3-thiazol-2-yl]amino]acetic acid
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|
C14H18N4O3S2
|
1
|
| 1 |
IC50 = 9930 nM
|
|
|
|
CP0066815
|
4-(2-amino-1,3-benzothiazol-6-yl)-1-(2-methoxyethoxy)pyridin-2-one
Show/Hide
|
C15H15N3O3S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0402073
|
N-[4-methyl-5-[2-[(4-methylcyclohexyl)amino]-1,3-thiazol-4-yl]-1,3-thiazol-2-yl]acetamide
Show/Hide
|
C16H22N4OS2
|
1
|
| 1 |
IC50 = 14160 nM
|
|
|
|
CP0093334
|
5-(2-amino-1,3-benzothiazol-6-yl)-N,N-dimethylpyridine-2-carboxamide
Show/Hide
|
C15H14N4OS
|
1
|
| 1 |
IC50 = 39810.72 nM
|
|
|
