Brief Information of the Cell Line and Protein
Cell Line ID: CL000012 , Sf21
 Cell Line Info 
Synonyms
SF21
Sf-21
SF-21
IPLB-SF-21-AE
IPLB-Sf21-AE
IPLB-SF21-AE
IPLB-SF 21AE
IPLB-Sf21AE
IPLB-SF21AE
IPLB-SF-21
IPLB-Sf-21
IPLB-SF 21
IPLB-Sf21
IPLB-SF21
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID
CVCL_0518
Protein ID: PT01786 , Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
 Protein Info 
Gene Name ENPP2
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q13822
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000012
 Cell Line Info 
 Protein ID: PT01786
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0562836
 Compound Info 
1-[4-[4-[[[6-[[6-(difluoromethyl)pyridin-3-yl]methoxy]pyridazin-3-yl]amino]methyl]-2-fluorophenyl]piperazin-1-yl]ethanone
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C24H25F3N6O2
  1
1
IC50 = 1.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0568049
 Compound Info 
1-[4-[4-[[[6-[[6-(difluoromethyl)pyridin-3-yl]methoxy]pyridazin-3-yl]amino]methyl]phenyl]-2,2-dimethylpiperazin-1-yl]ethanone
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C26H30F2N6O2
  1
1
IC50 = 1.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0572109
 Compound Info 
1-[5-[4-[[[6-[[6-(difluoromethyl)pyridin-3-yl]methoxy]pyridazin-3-yl]amino]methyl]phenyl]-2,5-diazabicyclo[2.2.1]heptan-2-yl]ethanone
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C25H26F2N6O2
  1
1
IC50 = 1.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0578685
 Compound Info 
6-[[6-(difluoromethyl)pyridin-3-yl]methoxy]-N-[[4-[4-(oxetan-3-yl)piperazin-1-yl]phenyl]methyl]pyridazin-3-amine
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C25H28F2N6O2
  1
1
IC50 = 1.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0520862
 Compound Info 
1-[4-[4-[[[6-[[6-(difluoromethyl)pyridin-3-yl]methoxy]pyridazin-3-yl]amino]methyl]-3-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone
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C25H25F5N6O2
  1
1
IC50 = 1.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0557283
 Compound Info 
1-[4-[6-[[[6-[[6-(difluoromethyl)pyridin-3-yl]methoxy]pyridazin-3-yl]amino]methyl]pyridin-3-yl]piperazin-1-yl]ethanone
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C23H25F2N7O2
  1
1
IC50 = 1.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS