| Compound ID |
Compound Name |
Compound Formula |
|
CP0329936
|
(2S)-3-phenyl-1-N-(2-pyridin-4-yl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)propane-1,2-diamine
Show/Hide
|
C24H25N5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0402115
|
4-piperazin-1-yl-2-pyridin-4-yl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine
Show/Hide
|
C19H21N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0849172
|
(S)-3-Phenyl-N'1-[2-(1H-pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
|
C22H24N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0850339
|
(R)-N'1-(9-Chloro-2-pyridin-4-yl-benzo[4,5]thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C18H16ClN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0850668
|
4-[1,4]Diazepan-1-yl-2-(3,5-dimethyl-1H-pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C20H26N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0852650
|
2-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C17H18N4OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0869158
|
(S)-3-Phenyl-N'1-(2-pyridin-4-yl-6,7,8,9-tetrahydro-5H-10-thia-1,3-diaza-benzo[a]azulen-4-yl)-propane-1,2-diamine
Show/Hide
|
C25H27N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0869208
|
4-[1,4]Diazepan-1-yl-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C20H23N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0874233
|
4-(2-Amino-ethylamino)-5-methyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidine-6-carboxylic acid amide
Show/Hide
|
C15H16N6OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0874234
|
N'1-Methyl-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C18H21N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0880966
|
4-((S)-3-Methyl-piperazin-1-yl)-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C20H23N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0880967
|
(S)-N'1-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C18H21N5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0896494
|
9-Chloro-4-piperazin-1-yl-2-pyridin-4-yl-benzo[4,5]thieno[3,2-d]pyrimidine
Show/Hide
|
C19H16ClN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0902208
|
N'1-(7-Methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C14H15N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0904460
|
N'1-[2-(3,5-Dimethyl-1H-pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-ethane-1,2-diamine
Show/Hide
|
C17H22N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0904469
|
N'1-(7-Methyl-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C18H21N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0904470
|
(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C19H21N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0904475
|
4-[1,4]Diazepan-1-yl-2-(1H-pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C18H22N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0911816
|
5-Methyl-4-piperazin-1-yl-2-pyridin-4-yl-thieno[2,3-d]pyrimidine
Show/Hide
|
C16H17N5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0911817
|
(S)-N'1-(2-Pyridin-4-yl-6,7,8,9-tetrahydro-5H-10-thia-1,3-diaza-benzo[a]azulen-4-yl)-propane-1,2-diamine
Show/Hide
|
C19H23N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0914009
|
(S)-1-Methyl-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C18H20N4OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0914010
|
(S)-2-Phenyl-1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxymethyl)-ethylamine
Show/Hide
|
C24H24N4OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0914016
|
4-[1,4]Diazepan-1-yl-5-methyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidine
Show/Hide
|
C17H19N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0914018
|
4-[1,4]Diazepan-1-yl-2-pyridin-4-yl-6,7,8,9-tetrahydro-5H-10-thia-1,3-diaza-benzo[a]azulene
Show/Hide
|
C21H25N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0914019
|
(S)-3-Phenyl-N'1-(2-pyridin-4-yl-5,6,7,8,9,10-hexahydro-11-thia-1,3-diaza-cycloocta[a]inden-4-yl)-propane-1,2-diamine
Show/Hide
|
C26H29N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0918227
|
(S)-N'1-(5-Isobutyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C18H23N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0918228
|
N'1-(5-Isobutyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C17H21N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0923175
|
(S)-N'1-(7,9-Dimethyl-2-pyridin-4-yl-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C19H20N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0947485
|
N'1-(2-Pyridin-4-yl-6,7,8,9-tetrahydro-5H-10-thia-1,3-diaza-benzo[a]azulen-4-yl)-ethane-1,2-diamine
Show/Hide
|
C18H21N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0947487
|
(S)-N'1-[2-(1H-Pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
|
C16H20N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951311
|
9-Chloro-4-[1,4]diazepan-1-yl-2-pyridin-4-yl-benzo[4,5]thieno[3,2-d]pyrimidine
Show/Hide
|
C20H18ClN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951860
|
(S)-N'1-(7-Methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C15H17N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951911
|
(S)-N'1-(9-Chloro-2-pyridin-4-yl-benzo[4,5]thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C18H16ClN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951935
|
(S)-N'1-(7-Methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C21H21N5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951955
|
N'1-(9-Chloro-2-pyridin-4-yl-benzo[4,5]thieno[3,2-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C17H14ClN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951959
|
7-Methyl-4-piperazin-1-yl-2-pyridin-4-yl-thieno[3,2-d]pyrimidine
Show/Hide
|
C16H17N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952727
|
4-Piperazin-1-yl-2-pyridin-4-yl-6,7,8,9-tetrahydro-5H-10-thia-1,3-diaza-benzo[a]azulene
Show/Hide
|
C20H23N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952729
|
4-((S)-2-Amino-3-phenyl-propylamino)-5-methyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidine-6-carboxylic acid amide
Show/Hide
|
C22H22N6OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952730
|
(S)-N'1-(7-Methyl-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C25H27N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952747
|
2-(3,5-Dimethyl-1H-pyrazol-4-yl)-4-piperazin-1-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C19H24N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952748
|
4-Piperazin-1-yl-2-(1H-pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C17H20N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952961
|
N'1-[2-(1H-Pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-ethane-1,2-diamine
Show/Hide
|
C15H18N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0953499
|
4-(4-Methyl-[1,4]diazepan-1-yl)-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C21H25N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0954352
|
4-[1,4]Diazepan-1-yl-7-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidine
Show/Hide
|
C17H19N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0960128
|
N(S)-N'1-(9-Chloro-2-pyridin-4-yl-benzo[4,5]thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H20ClN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0967311
|
N'1-(2-Pyridin-4-yl-5,6,7,8,9,10-hexahydro-11-thia-1,3-diaza-cycloocta[a]inden-4-yl)-ethane-1,2-diamine
Show/Hide
|
C19H23N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0967313
|
N-Methyl-N'-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C18H21N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0967317
|
[2-(3,5-Dimethyl-1H-pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C19H24N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0967621
|
4-(1S,4S)-2,5-Diaza-bicyclo[2.2.1]hept-2-yl-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C20H21N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0967916
|
(R)-N'1-(2-Pyridin-4-yl-6,7,8,9-tetrahydro-5H-10-thia-1,3-diaza-benzo[a]azulen-4-yl)-propane-1,2-diamine
Show/Hide
|
C19H23N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0967919
|
N'1-(5,6-Dimethyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C15H17N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0967922
|
(R)-N'1-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C18H21N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0967926
|
[2-(1H-Pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C17H20N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0849549
|
(S)-3-Phenyl-N'1-[2-pyridin-4-yl-7-(1H-pyrrol-2-yl)-thieno[3,2-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
|
C24H22N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0849550
|
(S)-N'1-(7-Bromo-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-methyl-butane-1,2-diamine
Show/Hide
|
C16H18BrN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0850337
|
(S)-3-Phenyl-N'1-[7-(2H-pyrazol-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
|
C23H21N7S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0850679
|
N'4-((S)-2-Amino-3-phenyl-propyl)-N'7-isoxazol-3-yl-2-pyridin-4-yl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
|
C23H21N7OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0850681
|
(S)-4-[2-Pyridin-4-yl-4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-7-yl]-but-3-yn-2-ol
Show/Hide
|
C19H19N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0850684
|
(S)-1-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-hex-1-yn-3-ol
Show/Hide
|
C26H27N5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0850723
|
(S)-N'1-[7-(5-Ethyl-2H-pyrazol-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C25H25N7S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0862376
|
N'7-(2-Fluoro-phenyl)-2-(3-fluoro-pyridin-4-yl)-N'4-(R)-pyrrolidin-3-yl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
|
C21H18F2N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0862377
|
4-[4-((S)-2-Amino-3-phenyl-propylamino)-2-(3-fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-7-yl]-2-methyl-but-3-yn-2-ol
Show/Hide
|
C25H24FN5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0862378
|
(S)-1-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-pent-1-yn-3-ol
Show/Hide
|
C25H25N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0862379
|
(S)-3-Phenyl-N'1-(2-pyridin-4-yl-7-pyridin-2-ylethynyl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C27H22N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0862380
|
(S)-3-Phenyl-N'1-(7-prop-1-ynyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C23H21N5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0862381
|
4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidine-7-carboxylic acid propylamide
Show/Hide
|
C24H26N6OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0862385
|
(S)-N'1-(7-Isoxazol-3-yl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C23H20N6OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866445
|
4-Morpholin-4-yl-N-{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-benzamide
Show/Hide
|
C26H27N7O2S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866460
|
(R)-Pyrrolidin-3-yl-{2-[2-(4-thiophen-2-yl-phenylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-amine
Show/Hide
|
C25H22N6S2
|
1
|
| 1 |
IC50 = 100 nM
|
|
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CP0866461
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4-Fluoro-N-{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-benzamide
Show/Hide
|
C22H19FN6OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866829
|
4-[4-((S)-2-Amino-3-phenyl-propylamino)-2-(3-fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-7-yl]-but-3-yn-1-ol
Show/Hide
|
C24H22FN5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866830
|
1-[4-((S)-2-Amino-3-phenyl-propylamino)-2-(3-fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-7-ylethynyl]-cyclobutanol
Show/Hide
|
C26H24FN5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866831
|
(S)-Tetrahydro-furan-2-carboxylic acid{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-amide
Show/Hide
|
C20H22N6O2S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866832
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3-Methoxy-N-{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-benzamide
Show/Hide
|
C23H22N6O2S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866842
|
3-[(S)-2-Amino-3-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-ylamino)-propyl]-phenol
Show/Hide
|
C24H25N5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866845
|
(S)-N'1-[7-Bromo-2-(3-fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C20H17BrFN5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0869168
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(S)-N'1-(7-Bromo-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C21H20BrN5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0869191
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(S)-3-Phenyl-N'1-[2-pyridin-4-yl-7-(1H-pyrrol-3-yl)-thieno[3,2-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
|
C24H22N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0869203
|
2-[(S)-2-Amino-3-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-ylamino)-propyl]-phenol
Show/Hide
|
C24H25N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0871097
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(S)-3-Phenyl-N'1-[7-(1H-pyrazol-4-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
|
C23H21N7S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0896792
|
N'4-((S)-2-Amino-3-phenyl-propyl)-N'7-phenyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
|
C26H24N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0896797
|
{2-[2-((R)-1-Phenyl-ethylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C23H24N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0900881
|
(S)-3-Pyridin-3-yl-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C23H24N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0903284
|
(S)-N'1-[7-(3-Methyl-thiophen-2-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C25H23N5S2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0904443
|
(S)-4-[4-((S)-2-Amino-3-phenyl-propylamino)-2-(3-fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-7-yl]-but-3-yn-2-ol
Show/Hide
|
C24H22FN5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0904447
|
{2-[2-(5-Phenyl-pyridin-2-ylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C26H23N7S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0904449
|
4-(4-Methyl-piperazin-1-yl)-N-{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-benzamide
Show/Hide
|
C27H30N8OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0904476
|
[7-(2H-Pyrazol-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C18H17N7S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0904478
|
(S)-3-Phenyl-N'1-(2-pyridin-4-yl-7-vinyl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C22H21N5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0904479
|
(S)-N'1-[7-(4-Fluoro-phenyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C26H22FN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0904480
|
(S)-N'1-(7-Cyclopropyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C23H23N5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0904481
|
(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-7-(1H-pyrazol-3-yl)-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C23H20FN7S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0904484
|
(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-7-furan-3-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H20FN5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0911819
|
(S)-3-Phenyl-N'1-(2-pyridin-4-yl-5,8-dihydro-6H-thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C23H23N5S2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0911820
|
(R)-3-Phenyl-N'1-1,4-Dioxa-spiro[7.7]-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C26H27N5O2S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0914001
|
1-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-ylethynyl]-cyclopropanol
Show/Hide
|
C25H23N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0914002
|
1-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-ylethynyl]-cyclobutanol
Show/Hide
|
C26H25N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0914003
|
4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidine-7-carboxylic acid cyclopropylamide
Show/Hide
|
C24H24N6OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0914004
|
1-Phenyl-3-{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-urea
Show/Hide
|
C22H21N7OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0914005
|
{2-[2-(Pyrazin-2-ylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C19H18N8S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0914020
|
(S)-N'1-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-3-thiazol-4-yl-propane-1,2-diamine
Show/Hide
|
C21H22N6S2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0914941
|
Thiophene-2-carboxylic acid{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-amide
Show/Hide
|
C20H18N6OS2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0914942
|
(2-{2-[5-(4-Methyl-piperazin-1-yl)-pyridin-2-ylamino]-pyridin-4-yl}-thieno[3,2-d]pyrimidin-4-yl)-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C25H29N9S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0916672
|
(S)-N'1-(6-Bromo-7-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C21H20BrN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0918201
|
N'4-((S)-2-Amino-3-phenyl-propyl)-2-pyridin-4-yl-N'7-pyrimidin-2-yl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
|
C24H22N8S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0918223
|
(S)-3-(2-Fluoro-phenyl)-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C24H24FN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0918224
|
(S)-N'1-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-3-m-tolyl-propane-1,2-diamine
Show/Hide
|
C25H27N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0918243
|
(S)-N'1-(7-Bromo-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-cyclohexyl-propane-1,2-diamine
Show/Hide
|
C20H24BrN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0918244
|
(7-Bromo-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-(R)-piperidin-3-yl-amine
Show/Hide
|
C16H16BrN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0918247
|
{2-[2-(6-Methyl-pyridazin-3-ylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C20H20N8S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0923180
|
(7-Bromo-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C16H16BrN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0923182
|
(S)-N'1-(6,7-Dimethyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C22H23N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0924090
|
(S)-3-Phenyl-N'1-[2-pyridin-4-yl-7-(2H-[1,2,3]triazol-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
|
C22H20N8S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0924091
|
4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidine-7-carboxylic acid methylamide
Show/Hide
|
C22H22N6OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0931112
|
(S)-N'1-[7-(5-Methyl-isoxazol-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H22N6OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0935589
|
{2-[2-((S)-1-Phenyl-ethylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C23H24N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0940846
|
(S)-N'1-(7-Pent-1-ynyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C25H25N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0947492
|
Cyclopropanecarboxylic acid{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-amide
Show/Hide
|
C19H20N6OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0950680
|
(S)-N'1-(7-Cyclopropylethynyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C25H23N5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951323
|
4-[4-((S)-2-Amino-3-phenyl-propylamino)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-2-methyl-but-3-yn-2-ol
Show/Hide
|
C26H27N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951324
|
3-[4-((S)-2-Amino-3-phenyl-propylamino)-2-(3-fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-7-yl]-prop-2-yn-1-ol
Show/Hide
|
C23H20FN5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951325
|
4-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-2-methyl-but-3-yn-2-ol
Show/Hide
|
C25H25N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951326
|
4-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-but-3-yn-2-ol
Show/Hide
|
C24H23N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951327
|
(S)-4-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-but-3-yn-2-ol
Show/Hide
|
C24H23N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951328
|
5-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-pent-4-yn-2-ol
Show/Hide
|
C25H25N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951329
|
(S)-5-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-pent-4-yn-2-ol
Show/Hide
|
C25H25N5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951331
|
(2-{2-[3-(4-Methyl-piperazin-1-yl)-phenylamino]-pyridin-4-yl}-thieno[3,2-d]pyrimidin-4-yl)-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C26H30N8S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951765
|
(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-7-(1H-pyrrol-2-yl)-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H21FN6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951785
|
(R)-Pyrrolidin-3-yl-{2-[2-(4-thiophen-3-yl-phenylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-amine
Show/Hide
|
C25H22N6S2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951858
|
(S)-N'1-[6-Methyl-7-(2H-pyrazol-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H23N7S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951875
|
(7-Bromo-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C15H14BrN5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951877
|
7-Bromo-4-piperazin-1-yl-2-pyridin-4-yl-thieno[3,2-d]pyrimidine
Show/Hide
|
C15H14BrN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951914
|
4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidine-7-carboxylic acid ethylamide
Show/Hide
|
C23H24N6OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951916
|
4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidine-7-carbonitrile
Show/Hide
|
C21H18N6S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951917
|
N'4-((S)-2-Amino-3-phenyl-propyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
|
C20H20N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951934
|
(S)-3-Phenyl-N'1-(2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C20H19N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951936
|
(S)-3-Phenyl-N'1-(7-phenylethynyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C28H23N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951938
|
(S)-N'1-[7-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C26H25N7S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952712
|
(7-Ethynyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C17H15N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952715
|
6-{4-[4-((R)-Pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-ylamino}-nicotinonitrile
Show/Hide
|
C21H18N8S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952716
|
{2-[2-(4-Piperidin-1-yl-phenylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C26H29N7S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952718
|
(4-Methyl-piperazin-1-yl)-(4-{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-ylamino}-phenyl)-methanone
Show/Hide
|
C27H30N8OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952733
|
(S)-N'1-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-3-o-tolyl-propane-1,2-diamine
Show/Hide
|
C25H27N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952749
|
(S)-3-Phenyl-N'1-[7-((Z)-propenyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
|
C23H23N5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0952751
|
(S)-3-Phenyl-N'1-(7-phenyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C26H23N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952762
|
2-Methyl-4-[2-pyridin-4-yl-4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-7-yl]-but-3-yn-2-ol
Show/Hide
|
C20H21N5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952763
|
(S)-1-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-3-methyl-pent-1-yn-3-ol
Show/Hide
|
C26H27N5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952957
|
(S)-N'1-(7-Bromo-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C14H14BrN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952975
|
2-Methyl-4-[6-methyl-2-pyridin-4-yl-4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-7-yl]-but-3-yn-2-ol
Show/Hide
|
C21H23N5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952976
|
3-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-prop-2-yn-1-ol
Show/Hide
|
C23H21N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0952977
|
5-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-2-methyl-pent-4-yn-2-ol
Show/Hide
|
C26H27N5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0953046
|
(S)-N'1-(7-Bromo-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C20H18BrN5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0953502
|
(R)-3-Phenyl-N'1-[7-(2H-pyrazol-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
|
C23H21N7S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0954136
|
(S)-N'1-[7-((E)-2-Cyclopropyl-vinyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C25H25N5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0954169
|
1-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-ylethynyl]-cyclopentanol
Show/Hide
|
C27H27N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0954183
|
(S)-N'1-[7-(4-Fluoro-but-1-ynyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H22FN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0954184
|
(E)-3-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-acrylic acid
Show/Hide
|
C23H21N5O2S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0954185
|
(S)-3-Phenyl-N'1-(2-pyridin-4-yl-7-[1,2,3]triazol-1-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C22H20N8S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0954188
|
{2-[2-(4-Imidazol-1-ylmethyl-phenylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C25H24N8S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0954690
|
N'1-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C17H19N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0954707
|
(S)-3-(4-Methoxy-phenyl)-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C25H27N5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0954721
|
(S)-N'1-[7-(3-Methyl-but-1-ynyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C25H25N5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0954722
|
(S)-N'1-[7-(3-Methoxy-3-methyl-but-1-ynyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C26H27N5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0954723
|
(S)-N'1-[7-(2-Fluoro-phenylethynyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C28H22FN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0954724
|
(S)-N'1-[7-(3-Methylamino-prop-1-ynyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H24N6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0954725
|
(S)-N'1-[7-((R)-3-Fluoro-but-1-ynyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H22FN5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0954829
|
{2-[2-(5-Morpholin-4-yl-pyridin-2-ylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C24H26N8OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0954836
|
(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-7-(1H-pyrrol-3-yl)-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H21FN6S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0956998
|
(S)-N'1-(7-Ethynyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C22H19N5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0960136
|
N'1-(7-Bromo-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C13H12BrN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0967300
|
N'4-((S)-2-Amino-3-phenyl-propyl)-2-pyridin-4-yl-N'7-pyridin-2-yl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
|
C25H23N7S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0967302
|
4-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-but-3-yn-1-ol
Show/Hide
|
C24H23N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0967303
|
(R)-4-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-but-3-yn-2-ol
Show/Hide
|
C24H23N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0967309
|
(S)-N'1-[7-(3-Fluoro-prop-1-ynyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C23H20FN5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0967315
|
(S)-N'1-(7-Chloro-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C20H18ClN5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0967318
|
(S)-N'1-[7-(3-Methoxy-prop-1-ynyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H23N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0967319
|
(S)-N'1-[7-((E)-3-Methoxy-propenyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H25N5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0967623
|
(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-7-furan-2-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H20FN5OS
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0967625
|
(S)-N'1-[7-(5-Methyl-1H-pyrazol-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H23N7S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0967883
|
(6-Bromo-7-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C16H16BrN5S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0967905
|
(S)-3-Phenyl-N'1-(2-pyridin-4-yl-7-thiazol-4-ylethynyl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C25H20N6S2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0967906
|
(S)-3-Phenyl-N'1-[7-(1H-pyrazol-3-ylethynyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
|
C25H21N7S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0967907
|
(S)-3-Phenyl-N'1-(7-pyrazol-1-yl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C23H21N7S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0967909
|
{2-[5-Fluoro-2-(pyrazin-2-ylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C19H17FN8S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0524279
|
4-(4-methylpiperazin-1-yl)-2-pyridin-4-yl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine
Show/Hide
|
C20H23N5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0849173
|
2-Pyridin-4-yl-4-((S)-pyrrolidin-3-yloxy)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C19H20N4OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0852649
|
(R)-1-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxymethyl)-propylamine
Show/Hide
|
C19H22N4OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0852654
|
5-(4-Bromo-phenyl)-4-[1,4]diazepan-1-yl-2-pyridin-4-yl-thieno[2,3-d]pyrimidine
Show/Hide
|
C22H20BrN5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0862375
|
7-Methyl-2-pyridin-4-yl-4-((R)-pyrrolidin-3-yloxy)-thieno[3,2-d]pyrimidine
Show/Hide
|
C16H16N4OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0862388
|
7,9-Dimethyl-4-piperazin-1-yl-2-pyridin-4-yl-pyrido[3',2':4,5]thieno[3,2-d]pyrimidine
Show/Hide
|
C20H20N6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0863132
|
(R)-1-Naphthalen-1-ylmethyl-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C28H26N4OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0863133
|
(S)-1-(4-Bromo-benzyl)-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C24H23BrN4OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0863138
|
(S)-2-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-1-thiophen-2-ylmethyl-ethylamine
Show/Hide
|
C22H22N4OS2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0866834
|
(S)-1-(3-Methyl-benzyl)-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C25H26N4OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0867707
|
(9-Chloro-2-pyridin-4-yl-benzo[4,5]thieno[3,2-d]pyrimidin-4-yl)-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C19H16ClN5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0869195
|
(7-Methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-(S)-pyrrolidin-3-yl-amine
Show/Hide
|
C16H17N5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0869201
|
(S)-1-(3-Fluoro-benzyl)-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C24H23FN4OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0871099
|
N'1-(9-Chloro-2-pyridin-4-yl-benzo[4,5]thieno[3,2-d]pyrimidin-4-yl)-N'1-methyl-ethane-1,2-diamine
Show/Hide
|
C18H16ClN5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0874195
|
(S)-1-Phenyl-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C23H22N4OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0874220
|
(R)-N'1-(7-Methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C15H17N5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0874221
|
N'1-Methyl-N'1-(7-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C15H17N5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0874226
|
4-(4-Ethyl-piperazin-1-yl)-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C21H25N5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0880965
|
(S)-N'1-(6-Isopropyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C23H25N5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0896812
|
2-Pyridin-4-yl-4-((S)-1-pyrrolidin-2-ylmethoxy)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C20H22N4OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0896815
|
4-(Azetidin-3-yloxy)-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C18H18N4OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0900869
|
(S)-N'1-[2-(3,5-Dimethyl-1H-pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H28N6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0900872
|
(S)-1-Cyclohexyl-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C23H28N4OS
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1
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| 1 |
IC50 = 1000 nM
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CP0900873
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2-Pyridin-4-yl-4-((R)-1-pyrrolidin-2-ylmethoxy)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
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C20H22N4OS
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1
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| 1 |
IC50 = 1000 nM
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CP0900882
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N'1-(6-Ethyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
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C15H17N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0900886
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(S)-N'1-(7-Methyl-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C19H23N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0903285
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4-[1,4]Diazepan-1-yl-7,9-dimethyl-2-pyridin-4-yl-pyrido[3',2':4,5]thieno[3,2-d]pyrimidine
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C21H22N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0904468
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(R)-N'1-(2-Pyridin-4-yl-5,6,7,8,9,10-hexahydro-11-thia-1,3-diaza-cycloocta[a]inden-4-yl)-propane-1,2-diamine
Show/Hide
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C20H25N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0904471
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4-((2R,5S)-2,5-Dimethyl-piperazin-1-yl)-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
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C21H25N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0904472
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(R)-3-(1H-Indol-3-yl)-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C26H26N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0910729
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(R)-N'1-(7,9-Dimethyl-2-pyridin-4-yl-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C19H20N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0911808
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Dimethyl-[2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethyl]-amine
Show/Hide
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C19H22N4OS
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1
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| 1 |
IC50 = 1000 nM
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CP0911814
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(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
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C18H20FN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0911815
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N'1-[2-(3-Fluoro-pyridin-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-ethane-1,2-diamine
Show/Hide
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C17H18FN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0911829
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(S)-1-(4-Methyl-benzyl)-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
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C25H26N4OS
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1
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| 1 |
IC50 = 1000 nM
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CP0911830
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(R)-3-Methyl-1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxymethyl)-butylamine
Show/Hide
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C21H26N4OS
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1
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| 1 |
IC50 = 1000 nM
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CP0914007
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(S)-1-(3-Methoxy-benzyl)-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
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C25H26N4O2S
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1
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| 1 |
IC50 = 1000 nM
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CP0914008
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4-((R)-1-Piperidin-2-ylmethoxy)-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
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C21H24N4OS
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1
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| 1 |
IC50 = 1000 nM
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CP0914014
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(R)-N'1-[2-(3-Fluoro-pyridin-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
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C18H20FN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0916670
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4-[1,4]Diazepan-1-yl-2-pyridin-4-yl-pyrido[3',2':4,5]thieno[3,2-d]pyrimidine
Show/Hide
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C19H18N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0918229
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(R)-N'1-(7-Methyl-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C19H23N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0918230
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N,N-Dimethyl-N'-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
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C19H23N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0918231
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(S)-N'1-[2-(3,5-Dimethyl-1H-pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
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C18H24N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0935569
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(S)-1-(4-Methoxy-benzyl)-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
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C25H26N4O2S
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1
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| 1 |
IC50 = 1000 nM
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CP0935570
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(S)-1-Naphthalen-1-ylmethyl-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
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C28H26N4OS
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1
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| 1 |
IC50 = 1000 nM
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CP0935572
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(S)-1-(2-Methyl-benzyl)-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
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C25H26N4OS
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1
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| 1 |
IC50 = 1000 nM
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CP0935573
|
(S)-1-Cyclohexylmethyl-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
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C24H30N4OS
|
1
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| 1 |
IC50 = 1000 nM
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CP0935574
|
(S)-2-Methyl-1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxymethyl)-propylamine
Show/Hide
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C20H24N4OS
|
1
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| 1 |
IC50 = 1000 nM
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CP0935575
|
4-(Piperidin-3-yloxy)-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
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C20H22N4OS
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1
|
| 1 |
IC50 = 1000 nM
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|
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CP0935579
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(R)-N'1-(5,6-Dimethyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C16H19N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0935580
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(S)-N'1-(6-Ethyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C16H19N5S
|
1
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| 1 |
IC50 = 1000 nM
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CP0935586
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(R)-N'1-[2-(1H-Pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
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C16H20N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0950885
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(S)-N'1-(2-Pyridin-4-yl-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C17H16N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0951760
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(R)-N'1-(6-Ethyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C16H19N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0951761
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(S)-N'1-(5-Ethyl-6-methyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C17H21N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0951763
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(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-(S)-pyrrolidin-3-yl-amine
Show/Hide
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C19H21N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0951932
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(R)-3-Phenyl-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C24H25N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0951933
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N'1-(6-Isopropyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
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C16H19N5S
|
1
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| 1 |
IC50 = 1000 nM
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CP0952139
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4-[1,4]Diazepan-1-yl-6-phenyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidine
Show/Hide
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C22H21N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0952726
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N'1-(6-Methyl-5-phenyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
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C20H19N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0952738
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(R)-N'1-(5-Isobutyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C18H23N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0952739
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4-((3R,5S)-3,5-Dimethyl-piperazin-1-yl)-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
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C21H25N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0954691
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(7-Methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-(R)-pyrrolidin-3-yl-amine
Show/Hide
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C16H17N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0954695
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(S)-1-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxymethyl)-propylamine
Show/Hide
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C19H22N4OS
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1
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| 1 |
IC50 = 1000 nM
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CP0954697
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(S)-3-Methyl-1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxymethyl)-butylamine
Show/Hide
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C21H26N4OS
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1
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| 1 |
IC50 = 1000 nM
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CP0954702
|
2-Pyridin-4-yl-4-(4-pyridin-4-ylmethyl-piperazin-1-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
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C25H26N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0956993
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(S)-N'1-(5,6-Dimethyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C16H19N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0967299
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9-Chloro-2-pyridin-4-yl-4-((S)-1-pyrrolidin-2-ylmethoxy)-benzo[4,5]thieno[3,2-d]pyrimidine
Show/Hide
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C20H17ClN4OS
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1
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| 1 |
IC50 = 1000 nM
|
|
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CP0967312
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(R)-4-Methyl-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-pentane-1,2-diamine
Show/Hide
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C21H27N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0967314
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(R)-4-Methylsulfanyl-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-butane-1,2-diamine
Show/Hide
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C20H25N5S2
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1
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| 1 |
IC50 = 1000 nM
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CP0967316
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6-Phenyl-4-piperazin-1-yl-2-pyridin-4-yl-thieno[3,2-d]pyrimidine
Show/Hide
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C21H19N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0967544
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N'1-(2-Pyridin-4-yl-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
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C16H14N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0967912
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(S)-1-(2-Fluoro-benzyl)-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
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C24H23FN4OS
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1
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| 1 |
IC50 = 1000 nM
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CP0967913
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(R)-1-Methyl-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
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C18H20N4OS
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1
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| 1 |
IC50 = 1000 nM
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CP0967914
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Methyl-[2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethyl]-amine
Show/Hide
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C18H20N4OS
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1
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| 1 |
IC50 = 1000 nM
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CP0967915
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4-[1,4]Diazepan-1-yl-6-methyl-5-phenyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidine
Show/Hide
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C23H23N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0967917
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(S)-N'1-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-butane-1,2-diamine
Show/Hide
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C19H23N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0967920
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(S)-N'1-(2-Pyridin-4-yl-5,6,7,8,9,10-hexahydro-11-thia-1,3-diaza-cycloocta[a]inden-4-yl)-propane-1,2-diamine
Show/Hide
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C20H25N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0967921
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(R)-N'1-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-butane-1,2-diamine
Show/Hide
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C19H23N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0848500
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(S)-N'1-{7-[(tert-Butyl-dimethyl-silanyl)-ethynyl]-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl}-3-phenyl-propane-1,2-diamine
Show/Hide
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C28H33N5SSi
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1
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| 1 |
IC50 = 1000 nM
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CP0848501
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(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C20H18FN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0849170
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(S)-N'1-[2-(5-Methyl-1H-pyrazol-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C19H20N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0850341
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(R)-N'1-[7-(4-Bromo-phenyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C26H22BrN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0850342
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(S)-N'1-[7-(4-Bromo-phenyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C26H22BrN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0850680
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N'7-(3-Fluoro-phenyl)-2-(3-fluoro-pyridin-4-yl)-N'4-(R)-pyrrolidin-3-yl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
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C21H18F2N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0850682
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4-[2-(3-Fluoro-pyridin-4-yl)-4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-7-yl]-2-methyl-but-3-yn-2-ol
Show/Hide
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C20H20FN5OS
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1
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| 1 |
IC50 = 1000 nM
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CP0850683
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(3R,4R)-1-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-hept-1-yne-3,4-diol
Show/Hide
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C27H29N5O2S
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1
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| 1 |
IC50 = 1000 nM
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CP0850686
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4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidine-7-carboxylic acid diethylamide
Show/Hide
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C25H28N6OS
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1
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| 1 |
IC50 = 1000 nM
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CP0850722
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2-Pyridin-4-yl-N'4-(R)-pyrrolidin-3-yl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
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C15H16N6S
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1
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| 1 |
IC50 = 1000 nM
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|
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CP0850724
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Piperidine-1-carboxylic acid{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-amide
Show/Hide
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C21H25N7OS
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1
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| 1 |
IC50 = 1000 nM
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CP0850725
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(S)-1-{4-[4-((R)-Pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-ylamino}-propan-2-ol
Show/Hide
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C18H22N6OS
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1
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| 1 |
IC50 = 1000 nM
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CP0852646
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(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
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C24H24FN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0852653
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4-[4-((S)-2-Amino-3-phenyl-propylamino)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-2-yl]-pyridin-3-ol
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C24H25N5OS
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1
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| 1 |
IC50 = 1000 nM
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CP0862369
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(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-7-phenyl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C26H22FN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0862382
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(S)-N'1-[7-Bromo-2-(1-oxy-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C20H18BrN5OS
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1
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| 1 |
IC50 = 1000 nM
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CP0862383
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(S)-N'1-[2-(1-Oxy-pyridin-4-yl)-7-(2H-pyrazol-3-yl)-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
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C23H21N7OS
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1
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| 1 |
IC50 = 1000 nM
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CP0862387
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(S)-N'1-[7-(2-Methyl-2H-pyrazol-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C24H23N7S
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1
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| 1 |
IC50 = 1000 nM
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CP0863141
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(S)-N'1-[7-(4-Aminomethyl-phenyl)-2-(3-fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C27H25FN6S
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1
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| 1 |
IC50 = 1000 nM
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CP0865032
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(S)-N'1-(7-Bromo-6-tert-butyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
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C24H26BrN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0866833
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2,2'-(2,2'-thiobis(pyridine-4,2-diyl))bis(N-((R)-pyrrolidin-3-yl)thieno[3,2-d]pyrimidin-4-amine)
Show/Hide
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C30H28N10S3
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1
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| 1 |
IC50 = 1000 nM
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CP0866843
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(S)-3-(4-Fluoro-phenyl)-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C24H24FN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0867460
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(S)-N'1-[2-(3-Chloro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
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C20H18ClN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0869160
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(R)-3-Phenyl-N'1-(2-pyridin-4-yl-6,7,8,9-tetrahydro-5H-10-thia-1,3-diaza-benzo[a]azulen-4-yl)-propane-1,2-diamine
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C25H27N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0869172
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(S)-N'1-(6-Methyl-7-phenyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
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C27H25N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0869192
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(S)-N'1-[7-(3,5-Dimethyl-isoxazol-4-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C25H24N6OS
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1
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| 1 |
IC50 = 1000 nM
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CP0869194
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(S)-N'1-(7-Bromo-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-4-methyl-pentane-1,2-diamine
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C17H20BrN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0869210
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N'1-(6,7-Dimethyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-ethane-1,2-diamine
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C15H17N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0871096
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(S)-N'1-[7-(4-Methyl-thiophen-2-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C25H23N5S2
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1
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| 1 |
IC50 = 1000 nM
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CP0874199
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(S)-N'1-[7-(3,5-Dimethyl-isoxazol-4-yl)-2-(3-fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C25H23FN6OS
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1
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| 1 |
IC50 = 1000 nM
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CP0874231
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(R)-1-Piperidin-2-ylmethyl-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-amine
Show/Hide
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C21H25N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0880961
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2-Pyridin-4-yl-4-((R)-pyrrolidin-3-yloxy)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
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C19H20N4OS
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1
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| 1 |
IC50 = 1000 nM
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CP0896793
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N'4-((S)-2-Amino-3-phenyl-propyl)-2-(3-fluoro-pyridin-4-yl)-N'7-phenyl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
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C26H23FN6S
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1
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| 1 |
IC50 = 1000 nM
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CP0896794
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2-Methyl-4-[7-methyl-2-pyridin-4-yl-4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-but-3-yn-2-ol
Show/Hide
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C21H23N5OS
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1
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| 1 |
IC50 = 1000 nM
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CP0896795
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[2-(2-Phenylamino-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
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C21H20N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0896796
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Furan-2-carboxylic acid{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-amide
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C20H18N6O2S
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1
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| 1 |
IC50 = 1000 nM
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CP0896798
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(R)-1-{4-[4-((R)-Pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-ylamino}-propan-2-ol
Show/Hide
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C18H22N6OS
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1
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| 1 |
IC50 = 1000 nM
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CP0896799
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[2-(2-Cyclopropylamino-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
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C18H20N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0896800
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N,N-Dimethyl-4-{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-ylamino}-benzenesulfonamide
Show/Hide
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C23H25N7O2S2
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1
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| 1 |
IC50 = 1000 nM
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CP0900876
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(S)-3-Phenyl-N'1-(2-pyridin-4-yl-5,8-dihydro-6H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C23H23N5OS
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1
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| 1 |
IC50 = 1000 nM
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CP0900879
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(S)-3-(1H-Indol-3-yl)-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C26H26N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0902306
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Thiophene-2-carboxylic acid{4-[4-((3S,4S)-4-hydroxy-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-amide
Show/Hide
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C20H18N6O2S2
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1
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| 1 |
IC50 = 1000 nM
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CP0904440
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2-Pyridin-4-yl-N'7-pyridin-2-yl-N'4-(R)-pyrrolidin-3-yl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
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C20H19N7S
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1
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| 1 |
IC50 = 1000 nM
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CP0904442
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4-[4-((S)-2-Amino-3-phenyl-propylamino)-6-tert-butyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-2-methyl-but-3-yn-2-ol
Show/Hide
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C29H33N5OS
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1
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| 1 |
IC50 = 1000 nM
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CP0904448
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4-{4-[4-((R)-Pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-ylamino}-benzonitrile
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C22H19N7S
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1
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| 1 |
IC50 = 1000 nM
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CP0904477
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(S)-N'1-[7-((E)-3,3-Dimethyl-but-1-enyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C26H29N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0904482
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(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-7-(5-trifluoromethyl-1H-pyrazol-3-yl)-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C24H19F4N7S
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1
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| 1 |
IC50 = 1000 nM
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CP0904483
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(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-7-pyrimidin-5-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C24H20FN7S
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1
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| 1 |
IC50 = 1000 nM
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CP0904487
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(S)-N'1-[6-tert-Butyl-7-(5-methyl-thiophen-2-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C29H31N5S2
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1
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| 1 |
IC50 = 1000 nM
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CP0911821
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[4-((R)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-5,8-dihydro-6H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-7-yl]-phenyl-methanone
Show/Hide
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C30H28N6OS
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1
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| 1 |
IC50 = 1000 nM
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CP0911822
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(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-7-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C25H21FN6S
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1
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| 1 |
IC50 = 1000 nM
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CP0914006
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1-Methyl-3-{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-urea
Show/Hide
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C17H19N7OS
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1
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| 1 |
IC50 = 1000 nM
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CP0914017
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4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-5,8-dihydro-6H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidine-7-carboxylic acid tert-butyl ester
Show/Hide
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C28H32N6O2S
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1
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| 1 |
IC50 = 1000 nM
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CP0914933
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[7-Methyl-6-(2H-pyrazol-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
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C19H19N7S
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1
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| 1 |
IC50 = 1000 nM
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CP0917528
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(S)-N'1-[7-(1-Isobutyl-1H-pyrazol-4-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C27H29N7S
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1
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| 1 |
IC50 = 1000 nM
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CP0918219
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(S)-N'1-[6-tert-Butyl-7-(2H-pyrazol-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C27H29N7S
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1
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| 1 |
IC50 = 1000 nM
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CP0918222
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(S)-3-Pyridin-2-yl-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C23H24N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0918226
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N'l-1,4-Dioxa-spiro[7.7]-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C19H21N5O2S
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1
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| 1 |
IC50 = 1000 nM
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CP0918232
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{4-[4-((S)-2-Amino-3-phenyl-propylamino)-2-(3-fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-7-yl]-phenyl}-methanol
Show/Hide
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C27H24FN5OS
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1
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| 1 |
IC50 = 1000 nM
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CP0918248
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{2-[2-((R)-1-Phenyl-propylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-(R)-pyrrolidin-3-yl-amine
Show/Hide
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C24H26N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0918249
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Thiophene-2-carboxylic acid{4-[4-((3S,4S)-1-carbamoylmethyl-4-hydroxy-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-amide
Show/Hide
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C22H21N7O3S2
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1
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| 1 |
IC50 = 1000 nM
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CP0923176
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N-(7-Bromo-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-N'-methyl-ethane-1,2-diamine
Show/Hide
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C14H14BrN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0923179
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(S)-N'1-(7-Bromo-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C15H16BrN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0923181
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[2-(3-Chloro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
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C15H14ClN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0924088
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(6-Ethynyl-7-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-(R)-pyrrolidin-3-yl-amine
Show/Hide
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C18H17N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0924092
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(2-{2-[3-(Propane-2-sulfonyl)-phenylamino]-pyridin-4-yl}-thieno[3,2-d]pyrimidin-4-yl)-(R)-pyrrolidin-3-yl-amine
Show/Hide
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C24H26N6O2S2
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1
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| 1 |
IC50 = 1000 nM
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CP0935581
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[2-(2-Benzylamino-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
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C22H22N6S
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1
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| 1 |
IC50 = 1000 nM
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CP0935587
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(S)-N'1-[6-tert-Butyl-7-(1H-pyrazol-4-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C27H29N7S
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1
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| 1 |
IC50 = 1000 nM
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CP0940847
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(S)-N'1-[7-(4-Fluoro-phenyl)-2-(3-fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C26H21F2N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0947490
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1-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-3-ethyl-pent-1-yn-3-ol
Show/Hide
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C27H29N5OS
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1
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| 1 |
IC50 = 1000 nM
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CP0947491
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[2-(5-Fluoro-2-phenylamino-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
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C21H19FN6S
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1
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| 1 |
IC50 = 1000 nM
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CP0950679
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(2-Pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-(R)-pyrrolidin-3-yl-amine
Show/Hide
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C15H15N5S
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1
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| 1 |
IC50 = 1000 nM
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CP0950886
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[7-Bromo-2-(3-fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
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C15H13BrFN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0950992
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4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidine-7-carboxylic acid isopropylamide
Show/Hide
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C24H26N6OS
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1
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| 1 |
IC50 = 1000 nM
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CP0951332
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(S)-N'1-[7-(6-Fluoro-pyridin-3-yl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C26H23FN6S
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1
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| 1 |
IC50 = 1000 nM
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CP0951455
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(R)-N'1-(7-Bromo-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C15H16BrN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0951456
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(R)-N'1-(7-Bromo-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
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C21H20BrN5S
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1
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| 1 |
IC50 = 1000 nM
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CP0951764
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(3S,4S)-4-(2-Pyridin-4-yl-thieno[3,2-d]pyrimidin-4-ylamino)-pyrrolidin-3-ol
Show/Hide
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C15H15N5OS
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1
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| 1 |
IC50 = 1000 nM
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CP0951766
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(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-7-thiophen-3-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C24H20FN5S2
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1
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| 1 |
IC50 = 1000 nM
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CP0951913
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(7-Bromo-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-(S)-pyrrolidin-3-yl-amine
Show/Hide
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C16H16BrN5S
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1
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| 1 |
IC50 = 1000 nM
|
|
|
|
CP0951915
|
4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidine-7-carboxylic acid tert-butylamide
Show/Hide
|
C25H28N6OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0951918
|
(R)-1-Phenyl-2-{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-ylamino}-ethanol
Show/Hide
|
C23H24N6OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0951919
|
3-{4-[4-((R)-Pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-ylamino}-benzonitrile
Show/Hide
|
C22H19N7S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0951920
|
Pyrazine-2-carboxylic acid{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-amide
Show/Hide
|
C20H18N8OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0952140
|
Thiophene-2-carboxylic acid{4-[4-((R)-1-methyl-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-amide
Show/Hide
|
C21H20N6OS2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0952709
|
(S)-N'1-[7-(3,3-Dimethyl-but-1-ynyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C26H27N5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0952710
|
(S)-1-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-3,4-dimethyl-pent-1-yn-3-ol
Show/Hide
|
C27H29N5OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0952711
|
4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidine-7-carboxylic acid dimethylamide
Show/Hide
|
C23H24N6OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0952713
|
{2-[2-((S)-1-Phenyl-propylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C24H26N6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0952714
|
{2-[2-(Pyridin-2-ylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C20H19N7S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0952717
|
(R)-Pyrrolidin-3-yl-{2-[2-(4-pyrrolidin-1-ylmethyl-phenylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-amine
Show/Hide
|
C26H29N7S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0952728
|
(R)-3-Phenyl-N'1-(2-pyridin-4-yl-5,8-dihydro-6H-thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C23H23N5S2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0952731
|
(S)-4,4-Dimethyl-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-pentane-1,2-diamine
Show/Hide
|
C22H29N5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0952734
|
(S)-3-(2-Methoxy-phenyl)-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C25H27N5OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0952735
|
N'1-(7,7-Dimethyl-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C19H23N5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0952741
|
(R)-Piperidin-3-yl-(2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-amine
Show/Hide
|
C16H17N5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0952746
|
4-((S)-3-Benzyl-piperazin-1-yl)-2-(1H-pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C24H26N6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0952753
|
(S)-N'1-[7-(4-Aminomethyl-furan-2-yl)-2-(3-fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C25H23FN6OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0953500
|
(S)-N'1-[7-(5-Methyl-furan-2-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C25H23N5OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954135
|
N'1-[7-(4-Bromo-phenyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-ethane-1,2-diamine
Show/Hide
|
C19H16BrN5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954137
|
(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-7-pyridin-3-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C25H21FN6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954144
|
(S)-3-Phenyl-N'1-1,4-Dioxa-spiro[7.7]-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C26H27N5O2S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954186
|
1,1-Dimethyl-3-{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-urea
Show/Hide
|
C18H21N7OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954187
|
1-tert-Butyl-3-{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-urea
Show/Hide
|
C20H25N7OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954704
|
[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-5,8-dihydro-6H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-7-yl]-phenyl-methanone
Show/Hide
|
C30H28N6OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954705
|
(S)-3-Benzo[b]thiophen-3-yl-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C26H25N5S2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954706
|
(R)-3-Naphthalen-1-yl-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C28H27N5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954708
|
(S)-N'1-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-3-p-tolyl-propane-1,2-diamine
Show/Hide
|
C25H27N5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954719
|
2-(3-Fluoro-pyridin-4-yl)-N'4-(R)-pyrrolidin-3-yl-N'7-o-tolyl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
|
C22H21FN6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954720
|
(S)-N'1-[7-(3-Amino-3-methyl-but-1-ynyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C25H26N6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954826
|
1-[4-(2-Amino-ethylamino)-2-pyridin-4-yl-5,8-dihydro-6H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-7-yl]-ethanone
Show/Hide
|
C18H20N6OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954830
|
[2-(2-Isopropylamino-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C18H22N6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954838
|
(S)-N'1-[7-(2-Cyclopropyl-ethyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C25H27N5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0954839
|
{2-[2-(Cyclopropylmethyl-amino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C19H22N6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0956992
|
N'1-(2-Pyridin-4-yl-5,8-dihydro-6H-thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C16H17N5S2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0956994
|
(S)-3-Phenyl-N'1-(2-pyridin-4-yl-7-pyridin-3-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C25H22N6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0956995
|
(S)-N'1-[7-(1-Methyl-1H-pyrazol-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H23N7S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0959001
|
(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-7-o-tolyl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C27H24FN5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0962409
|
(7-Bromo-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-(S)-pyrrolidin-3-yl-amine
Show/Hide
|
C15H14BrN5S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0967301
|
N'4-((S)-2-Amino-3-phenyl-propyl)-2-pyridin-4-yl-N'7-pyrimidin-4-yl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
|
C24H22N8S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0967305
|
5-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-pent-4-yn-1-ol
Show/Hide
|
C25H25N5OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0967320
|
{3-[4-((S)-2-Amino-3-phenyl-propylamino)-2-(3-fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-7-yl]-phenyl}-methanol
Show/Hide
|
C27H24FN5OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0967321
|
(S)-N'1-[6-tert-Butyl-7-(4-methylamino-phenyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C31H34N6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0967619
|
(S)-3-Pyridin-4-yl-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C23H24N6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0967620
|
(S)-3-(3-Methoxy-phenyl)-N'1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C25H27N5OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0967908
|
(S)-N'1-[7-(5-Ethyl-isoxazol-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C25H24N6OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0967910
|
{2-[3-Fluoro-2-(pyrazin-2-ylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C19H17FN8S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0967918
|
4-[(S)-2-Amino-3-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-ylamino)-propyl]-phenol
Show/Hide
|
C24H25N5OS
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0967927
|
(S)-N'1-[7-(1-Methyl-1H-pyrazol-4-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H23N7S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0850340
|
(R)-N'1-[6-(4-tert-Butyl-phenyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
|
C24H27N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0850678
|
7-Methyl-2-pyridin-4-yl-4-((S)-1-pyrrolidin-2-ylmethoxy)-thieno[3,2-d]pyrimidine
Show/Hide
|
C17H18N4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0852647
|
(R)-2-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-1-thiophen-2-ylmethyl-ethylamine
Show/Hide
|
C22H22N4OS2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0852648
|
(S)-1-(4-Fluoro-benzyl)-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C24H23FN4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0852651
|
4-[4-(4-Methyl-benzyl)-piperazin-1-yl]-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C27H29N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0862392
|
4-[4-(2-Chloro-benzyl)-piperazin-1-yl]-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C26H26ClN5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0863134
|
2-Pyridin-4-yl-4-[4-(4-trifluoromethyl-benzyl)-piperazin-1-yl]-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C27H26F3N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0866836
|
4-[4-(4-Bromo-benzyl)-piperazin-1-yl]-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C26H26BrN5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0867708
|
(R)-N'1-(2-Pyridin-4-yl-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C17H16N6S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0867709
|
6-(4-tert-Butyl-phenyl)-4-[1,4]diazepan-1-yl-2-pyridin-4-yl-thieno[3,2-d]pyrimidine
Show/Hide
|
C26H29N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0874186
|
4-(4-Benzyl-piperazin-1-yl)-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C26H27N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0874188
|
(S)-N'1-(6-tert-Butyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C18H23N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0874193
|
4-((S)-1-Piperidin-2-ylmethoxy)-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C21H24N4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0874194
|
(R)-3-Phenyl-1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxymethyl)-propylamine
Show/Hide
|
C25H26N4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0880962
|
4-(4-Propyl-piperazin-1-yl)-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C22H27N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0880963
|
4-[4-(3-Bromo-pyridin-4-ylmethyl)-piperazin-1-yl]-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C25H25BrN6S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0900870
|
(S)-1-(1H-Indol-3-ylmethyl)-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C26H25N5OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0903286
|
N'1-[6-(4-tert-Butyl-phenyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-ethane-1,2-diamine
Show/Hide
|
C23H25N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0904439
|
9-Chloro-2-pyridin-4-yl-4-((R)-1-pyrrolidin-2-ylmethoxy)-benzo[4,5]thieno[3,2-d]pyrimidine
Show/Hide
|
C20H17ClN4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0904462
|
(S)-1-Benzo[b]thiophen-3-ylmethyl-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C26H24N4OS2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0904463
|
(R)-1-Benzo[b]thiophen-3-ylmethyl-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C26H24N4OS2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0904473
|
N'1-(6-Phenyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C19H17N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0904474
|
(R)-N'1-(6-tert-Butyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C18H23N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0911809
|
4-[4-(3-Bromo-benzyl)-piperazin-1-yl]-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C26H26BrN5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0911811
|
4-[4-(3-Chloro-benzyl)-piperazin-1-yl]-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C26H26ClN5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0911827
|
(R)-1-Naphthalen-2-ylmethyl-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C28H26N4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0911828
|
(R)-1-(4-Methoxy-benzyl)-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C25H26N4O2S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0914011
|
4-(4-Isobutyl-piperazin-1-yl)-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C23H29N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0914012
|
2-Pyridin-4-yl-4-(4-pyridin-3-ylmethyl-piperazin-1-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C25H26N6S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0914015
|
N'1-[2-(2-Fluoro-pyridin-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-ethane-1,2-diamine
Show/Hide
|
C17H18FN5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0918220
|
7-Methyl-2-pyridin-4-yl-4-((R)-1-pyrrolidin-2-ylmethoxy)-thieno[3,2-d]pyrimidine
Show/Hide
|
C17H18N4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0918221
|
(S)-1-Benzyl-2-(7-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C21H20N4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0935571
|
(S)-1-(1H-Imidazol-4-ylmethyl)-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C21H22N6OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0935577
|
4-[4-(6-Bromo-pyridin-3-ylmethyl)-piperazin-1-yl]-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C25H25BrN6S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0951320
|
(R)-1-Benzyl-2-(9-chloro-2-pyridin-4-yl-benzo[4,5]thieno[3,2-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C24H19ClN4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0951321
|
(R)-1-Benzyl-2-(7-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C21H20N4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0951929
|
(R)-1-Phenyl-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C23H22N4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0951930
|
(R)-2-Phenyl-1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxymethyl)-ethylamine
Show/Hide
|
C24H24N4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0951931
|
4-[4-(4-Chloro-benzyl)-piperazin-1-yl]-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C26H26ClN5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0952449
|
(R)-N'1-(6-Isopropyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C17H21N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0952450
|
(R)-N'1-[2-(3,5-Dimethyl-1H-pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
|
C18H24N6S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0952736
|
(R)-N'1-(5-Ethyl-6-methyl-2-pyridin-4-yl-thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C17H21N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0952743
|
N'1-(6-tert-Butyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C17H21N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0952955
|
(1S,2S)-N-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-cyclopropane-1,2-diamine
Show/Hide
|
C18H19N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0953951
|
7-Methyl-2-pyridin-4-yl-4-((S)-pyrrolidin-3-yloxy)-thieno[3,2-d]pyrimidine
Show/Hide
|
C16H16N4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0954696
|
(R)-2-Methyl-1-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxymethyl)-propylamine
Show/Hide
|
C20H24N4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0954698
|
4-(4-Butyl-piperazin-1-yl)-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C23H29N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0954700
|
3-[4-(2-Pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-piperazin-1-ylmethyl]-phenol
Show/Hide
|
C26H27N5OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0954701
|
2-Pyridin-4-yl-4-(4-pyridin-2-ylmethyl-piperazin-1-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C25H26N6S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0954825
|
4-(4-Phenethyl-piperazin-1-yl)-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine
Show/Hide
|
C27H29N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0960129
|
(S)-N'1-[6-(4-tert-Butyl-phenyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
|
C24H27N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0960131
|
(S)-N'1-(6-Phenyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C20H19N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0960133
|
(R)-N'1-(6-Phenyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
|
C20H19N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0967249
|
4-Piperazin-1-yl-2-pyridin-4-yl-pyrido[3',2':4,5]thieno[3,2-d]pyrimidine
Show/Hide
|
C18H16N6S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0967911
|
(S)-1-Naphthalen-2-ylmethyl-2-(2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yloxy)-ethylamine
Show/Hide
|
C28H26N4OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0849174
|
N'1-(7-Isobutyl-2-pyridin-4-yl-5,6,7,8-tetrahydro-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C20H26N6S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0850669
|
(S)-N'1-[7-(5-Fluoro-2-isopropoxy-phenyl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C30H30FN5OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0850677
|
(S)-N'1-[7-(2-Methoxy-pyridin-3-yl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C27H26N6OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0850685
|
(S)-4-[2-(3-Fluoro-pyridin-4-yl)-4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-7-yl]-but-3-yn-2-ol
Show/Hide
|
C19H18FN5OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0852644
|
1-[4-(2-Amino-ethylamino)-2-pyridin-4-yl-5,8-dihydro-6H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-7-yl]-2-dimethylamino-ethanone
Show/Hide
|
C20H25N7OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0852645
|
[4-(2-Amino-ethylamino)-2-pyridin-4-yl-5,8-dihydro-6H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-7-yl]-cyclobutyl-methanone
Show/Hide
|
C21H24N6OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0852652
|
1-[4-(2-Amino-ethylamino)-2-pyridin-4-yl-5,8-dihydro-6H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-7-yl]-pentan-1-one
Show/Hide
|
C21H26N6OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0852656
|
(S)-N'1-[7-(2,4-Dimethyl-thiazol-5-yl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C26H26N6S2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0862373
|
Cyclopentanecarboxylic acid [4-((S)-2-amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-amide
Show/Hide
|
C26H28N6OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0862374
|
Cyclohexanecarboxylic acid [2-pyridin-4-yl-4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-7-yl]-amide
Show/Hide
|
C22H26N6OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0862389
|
N'-(7-Bromo-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-N,N-dimethyl-ethane-1,2-diamine
Show/Hide
|
C15H16BrN5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0866446
|
N-{4-[4-((R)-Pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-methanesulfonamide
Show/Hide
|
C16H18N6O2S2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0866457
|
(S)-N'1-[6-Methyl-7-(2-methyl-pyridin-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C27H26N6S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0866458
|
2-(3-Fluoro-pyridin-4-yl)-N'7-pyridin-3-yl-N'4-(R)-pyrrolidin-3-yl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
|
C20H18FN7S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0866462
|
[2-(3-Fluoro-2-phenylamino-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C21H19FN6S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0866839
|
N'1-(7-Methyl-2-pyridin-4-yl-5,6,7,8-tetrahydro-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
|
C17H20N6S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0866844
|
((2R,3R)-2-Fluoro-pyrrolidin-3-yl)-(2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-amine
Show/Hide
|
C15H14FN5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0867461
|
(S)-N'1-(6-tert-Butyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H27N5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0869196
|
2-(7-Bromo-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-ylamino)-acetamide
Show/Hide
|
C13H10BrN5OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0869197
|
(R)-N'1-(7-Bromo-6-tert-butyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
|
C24H26BrN5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0871102
|
(7-Bromo-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-(S)-1-pyrrolidin-2-ylmethyl-amine
Show/Hide
|
C16H16BrN5S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0874187
|
1-[4-(2-Amino-ethylamino)-2-pyridin-4-yl-5,8-dihydro-6H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-7-yl]-2-methyl-propan-1-one
Show/Hide
|
C20H24N6OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0874200
|
(S)-N'1-[7-(2-Chloro-6-methoxy-phenyl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C28H26ClN5OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0874201
|
(S)-N'1-[7-(2-Isobutoxy-6-methoxy-phenyl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C32H35N5O2S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0874212
|
(S)-N'1-[7-(5-Chloro-2-isopropoxy-phenyl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C30H30ClN5OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0874213
|
(S)-N'1-[7-(5-tert-Butyl-2-methoxy-phenyl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C32H35N5OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0874227
|
4-(2-Amino-ethylamino)-2-pyridin-4-yl-5,8-dihydro-6H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidine-7-carboxylic acid tert-butyl ester
Show/Hide
|
C21H26N6O2S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0874228
|
(S)-N'1-[2-(3-Methoxy-pyridin-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
|
C25H27N5OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0896791
|
Cyclopentanecarboxylic acid [2-pyridin-4-yl-4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-7-yl]-amide
Show/Hide
|
C21H24N6OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0902305
|
[2-(2-Cyclohexylamino-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
|
C21H26N6S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0902307
|
Thiophene-2-carboxylic acid(4-{4-[(S)-2-amino-3-(4-trifluoromethyl-phenyl)-propylamino]-thieno[3,2-d]pyrimidin-2-yl}-pyridin-2-yl)-amide
Show/Hide
|
C26H21F3N6OS2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0903385
|
N-[4-((S)-2-Amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-2,2-dimethyl-butyramide
Show/Hide
|
C26H30N6OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
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CP0904438
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[7-Methyl-6-(2-methyl-2H-pyrazol-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
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C20H21N7S
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1
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| 1 |
IC50 = 10000 nM
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CP0904441
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2-(3-Fluoro-pyridin-4-yl)-N'7-pyridin-2-yl-N'4-(R)-pyrrolidin-3-yl-thieno[3,2-d]pyrimidine-4,7-diamine
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C20H18FN7S
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1
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| 1 |
IC50 = 10000 nM
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CP0904450
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Cyclopropanesulfonic acid{4-[4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-amide
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C18H20N6O2S2
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1
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| 1 |
IC50 = 10000 nM
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CP0904465
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(S)-3-(2-Methoxy-phenyl)-N'1-(2-pyridin-4-yl-5,8-dihydro-6H-thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
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C24H25N5OS2
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1
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| 1 |
IC50 = 10000 nM
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CP0904485
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(S)-N'1-[6-tert-Butyl-7-(6-fluoro-pyridin-3-yl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C29H29FN6S
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1
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| 1 |
IC50 = 10000 nM
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CP0904486
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(S)-N'1-[7-(3-Amino-phenyl)-6-tert-butyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
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C30H32N6S
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1
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| 1 |
IC50 = 10000 nM
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CP0904488
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(S)-N'1-[7-(2,6-Dimethoxy-phenyl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C29H29N5O2S
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1
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| 1 |
IC50 = 10000 nM
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CP0911818
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(R)-3-Phenyl-N'1-(2-pyridin-4-yl-5,8-dihydro-6H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl)-propane-1,2-diamine
Show/Hide
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C23H23N5OS
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1
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| 1 |
IC50 = 10000 nM
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CP0911823
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(S)-N'1-[6-tert-Butyl-7-(3-methoxy-phenyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C31H33N5OS
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1
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| 1 |
IC50 = 10000 nM
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CP0911824
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(S)-N'1-[6-tert-Butyl-7-(4-fluoro-phenyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C30H30FN5S
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1
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| 1 |
IC50 = 10000 nM
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CP0914013
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N'1-(7-Ethyl-2-pyridin-4-yl-5,6,7,8-tetrahydro-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
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C18H22N6S
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1
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| 1 |
IC50 = 10000 nM
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CP0914943
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(R)-Pyrrolidin-3-yl-{2-[2-(tetrahydro-pyran-4-ylamino)-pyridin-4-yl]-thieno[3,2-d]pyrimidin-4-yl}-amine
Show/Hide
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C20H24N6OS
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1
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| 1 |
IC50 = 10000 nM
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CP0918218
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(S)-N'1-[7-(2-Methoxy-5-trifluoromethyl-phenyl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C29H26F3N5OS
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1
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| 1 |
IC50 = 10000 nM
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CP0918225
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N'1-(2-Pyridin-4-yl-5,8-dihydro-6H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
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C16H17N5OS
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1
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| 1 |
IC50 = 10000 nM
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CP0923177
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(7-Bromo-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-(R)-1-pyrrolidin-2-ylmethyl-amine
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C16H16BrN5S
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1
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| 1 |
IC50 = 10000 nM
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CP0935578
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[4-(2-Amino-ethylamino)-2-pyridin-4-yl-5,8-dihydro-6H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-7-yl]-cyclopropyl-methanone
Show/Hide
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C20H22N6OS
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1
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| 1 |
IC50 = 10000 nM
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CP0940831
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1-[4-(2-Amino-ethylamino)-2-pyridin-4-yl-5,8-dihydro-6H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-7-yl]-propan-1-one
Show/Hide
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C19H22N6OS
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1
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| 1 |
IC50 = 10000 nM
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CP0940848
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(S)-N'1-[7-(4-Methoxy-pyridin-3-yl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C27H26N6OS
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1
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| 1 |
IC50 = 10000 nM
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CP0947488
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(S)-N'1-[6-tert-Butyl-7-(3-fluoro-phenyl)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C30H30FN5S
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1
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| 1 |
IC50 = 10000 nM
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CP0947489
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(S)-N'1-[7-(2-Isopropoxy-5-methyl-phenyl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C31H33N5OS
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1
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| 1 |
IC50 = 10000 nM
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CP0947494
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[2-(5-Methyl-1H-pyrazol-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
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C14H16N6S
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1
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| 1 |
IC50 = 10000 nM
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CP0951319
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(S)-N'1-[7-(5-Isopropyl-2-methoxy-phenyl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C31H33N5OS
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1
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| 1 |
IC50 = 10000 nM
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CP0951322
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2-(3-Fluoro-pyridin-4-yl)-N'7-(5-methyl-isoxazol-3-yl)-N'4-(R)-pyrrolidin-3-yl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
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C19H18FN7OS
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1
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| 1 |
IC50 = 10000 nM
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CP0951762
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[4-(2-Amino-ethylamino)-2-pyridin-4-yl-5,8-dihydro-6H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-7-yl]-phenyl-methanone
Show/Hide
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C23H22N6OS
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1
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| 1 |
IC50 = 10000 nM
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CP0951767
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(S)-N'1-[7-(2-Chloro-phenyl)-2-pyridin-4-yl-6-trifluoromethyl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C27H21ClF3N5S
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1
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| 1 |
IC50 = 10000 nM
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CP0951777
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(S)-N'1-[7-(5-Fluoro-2-methoxy-phenyl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C28H26FN5OS
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1
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| 1 |
IC50 = 10000 nM
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CP0951778
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2,2-Dimethyl-N-[2-pyridin-4-yl-4-((R)-pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-7-yl]-butyramide
Show/Hide
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C21H26N6OS
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1
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| 1 |
IC50 = 10000 nM
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CP0951873
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(S)-N'1-[2-(3-Fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-propane-1,2-diamine
Show/Hide
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C14H14FN5S
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1
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| 1 |
IC50 = 10000 nM
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CP0951912
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6-(4-tert-Butyl-phenyl)-4-piperazin-1-yl-2-pyridin-4-yl-thieno[3,2-d]pyrimidine
Show/Hide
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C25H27N5S
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1
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| 1 |
IC50 = 10000 nM
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CP0951939
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(S)-N'1-(6-tert-Butyl-7-furan-3-yl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
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C28H29N5OS
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1
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| 1 |
IC50 = 10000 nM
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CP0951940
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(S)-N'1-[7-(2-Methoxy-5-methyl-phenyl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C29H29N5OS
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1
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| 1 |
IC50 = 10000 nM
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CP0952452
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(S)-N'1-[7-(5-Chloro-2-ethoxy-phenyl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C29H28ClN5OS
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1
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| 1 |
IC50 = 10000 nM
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CP0952740
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2-[(R)-3-(2-Pyridin-4-yl-thieno[3,2-d]pyrimidin-4-ylamino)-pyrrolidin-1-yl]-acetamide
Show/Hide
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C17H18N6OS
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1
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| 1 |
IC50 = 10000 nM
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CP0952744
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(S)-N'1-(7-Bromo-6-tert-butyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-(2-methoxy-phenyl)-propane-1,2-diamine
Show/Hide
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C25H28BrN5OS
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1
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| 1 |
IC50 = 10000 nM
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CP0952754
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(S)-N'1-(6-tert-Butyl-7-phenyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
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C30H31N5S
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1
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| 1 |
IC50 = 10000 nM
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CP0952755
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(S)-N'1-[7-(3-Methoxy-pyridin-4-yl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C27H26N6OS
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1
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| 1 |
IC50 = 10000 nM
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CP0952761
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2-(3-Fluoro-pyridin-4-yl)-N'4-(R)-pyrrolidin-3-yl-N'7-m-tolyl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
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C22H21FN6S
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1
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| 1 |
IC50 = 10000 nM
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CP0953542
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[2-(3-Fluoro-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-yl]-(R)-pyrrolidin-3-yl-amine
Show/Hide
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C15H14FN5S
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1
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| 1 |
IC50 = 10000 nM
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CP0953952
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N'7-(4-Fluoro-phenyl)-2-(3-fluoro-pyridin-4-yl)-N'4-(R)-pyrrolidin-3-yl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
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C21H18F2N6S
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1
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| 1 |
IC50 = 10000 nM
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CP0954138
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(S)-N'1-[7-(2-Isopropoxy-6-methoxy-phenyl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C31H33N5O2S
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1
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| 1 |
IC50 = 10000 nM
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CP0954168
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2-(3-Fluoro-pyridin-4-yl)-N'7-isoxazol-3-yl-N'4-(R)-pyrrolidin-3-yl-thieno[3,2-d]pyrimidine-4,7-diamine
Show/Hide
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C18H16FN7OS
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1
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| 1 |
IC50 = 10000 nM
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CP0954694
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2-{(R)-3-[2-(2-Phenylamino-pyridin-4-yl)-thieno[3,2-d]pyrimidin-4-ylamino]-pyrrolidin-1-yl}-acetamide
Show/Hide
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C23H23N7OS
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1
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| 1 |
IC50 = 10000 nM
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CP0954703
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4-((S)-2-Amino-propylamino)-2-pyridin-4-yl-5,8-dihydro-6H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidine-7-carboxylic acid tert-butyl ester
Show/Hide
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C22H28N6O2S
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1
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| 1 |
IC50 = 10000 nM
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CP0954827
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(S)-N'1-(7,7-Dimethyl-2-pyridin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-3-phenyl-propane-1,2-diamine
Show/Hide
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C26H29N5S
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1
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| 1 |
IC50 = 10000 nM
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CP0964062
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(S)-N'1-[7-(2,5-Dimethoxy-phenyl)-6-methyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl]-3-phenyl-propane-1,2-diamine
Show/Hide
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C29H29N5O2S
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1
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| 1 |
IC50 = 10000 nM
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CP0967250
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N'1-(7-Bromo-6-tert-butyl-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-ethane-1,2-diamine
Show/Hide
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C17H20BrN5S
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1
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| 1 |
IC50 = 10000 nM
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CP0967298
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Cyclohexanecarboxylic acid [4-((S)-2-amino-3-phenyl-propylamino)-2-pyridin-4-yl-thieno[3,2-d]pyrimidin-7-yl]-amide
Show/Hide
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C27H30N6OS
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1
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| 1 |
IC50 = 10000 nM
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CP0967310
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N-{4-[4-((R)-Pyrrolidin-3-ylamino)-thieno[3,2-d]pyrimidin-2-yl]-pyridin-2-yl}-benzenesulfonamide
Show/Hide
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C21H20N6O2S2
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1
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| 1 |
IC50 = 10000 nM
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CP0967923
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(R)-1-(2-Pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-pyrrolidin-3-ylamine
Show/Hide
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C15H15N5S
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1
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| 1 |
IC50 = 10000 nM
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CP0967924
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((3S,4S)-1-Benzyl-4-fluoro-pyrrolidin-3-yl)-(2-pyridin-4-yl-thieno[3,2-d]pyrimidin-4-yl)-amine
Show/Hide
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C22H20FN5S
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1
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| 1 |
IC50 = 10000 nM
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CP0869164
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N'1-[2-(1-Methyl-1H-pyrazol-4-yl)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl]-ethane-1,2-diamine
Show/Hide
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C16H20N6S
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1
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| 1 |
IC50 > 60000 nM
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