| Compound ID |
Compound Name |
Compound Formula |
|
CP0533266
|
1-(3,4-dimethoxyphenyl)-1-[(4-fluorophenyl)methyl]-3-[3-(5-methylimidazol-1-yl)propyl]thiourea
Show/Hide
|
C23H27FN4O2S
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0492192
|
1-[4-[2-(2-aminoethylamino)pyridin-4-yl]butyl]-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C27H39N7O3
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0330750
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-propan-2-ylthiourea
Show/Hide
|
C19H28N4O2S
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0115637
|
1-(3,4-dimethoxyphenyl)-1-[(3-fluorophenyl)methyl]-3-[3-(5-methylimidazol-1-yl)propyl]thiourea
Show/Hide
|
C23H27FN4O2S
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0354439
|
1-[(3-chlorophenyl)methyl]-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]thiourea
Show/Hide
|
C23H27ClN4O2S
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0096899
|
1-[4-(2-aminopyridin-4-yl)butyl]-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C25H34N6O3
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0365776
|
1-(3,4-dimethoxyphenyl)-1-[(4-fluorophenyl)methyl]-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C23H27FN4O3
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0126406
|
1-(cyclopentylmethyl)-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]thiourea
Show/Hide
|
C22H32N4O2S
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0103701
|
1-[4-[4-(2-aminopyridin-4-yl)butoxy]-3-methoxyphenyl]-3-[3-(5-methylimidazol-1-yl)propyl]thiourea
Show/Hide
|
C24H32N6O2S
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0354441
|
1-cyclohexyl-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C22H32N4O3
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0330751
|
1-benzyl-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]thiourea
Show/Hide
|
C23H28N4O2S
|
1
|
| 1 |
IC50 = 4.6 nM
|
|
|
|
CP0354438
|
1-cyclohexyl-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]thiourea
Show/Hide
|
C22H32N4O2S
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0354440
|
1-[(4-chlorophenyl)methyl]-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]thiourea
Show/Hide
|
C23H27ClN4O2S
|
1
|
| 1 |
IC50 = 5.2 nM
|
|
|
|
CP0236701
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-(pyridin-3-ylmethyl)thiourea
Show/Hide
|
C22H27N5O2S
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0327213
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-(pyridin-4-ylmethyl)thiourea
Show/Hide
|
C22H27N5O2S
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0271116
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
|
C22H33N5O3
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0364333
|
1-(cyclopentylmethyl)-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C22H32N4O3
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0364358
|
1-cyclopentyl-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]thiourea
Show/Hide
|
C21H30N4O2S
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0096791
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-(2-methylpropyl)thiourea
Show/Hide
|
C20H30N4O2S
|
1
|
| 1 |
IC50 = 6.8 nM
|
|
|
|
CP0240146
|
1-(1-benzylpiperidin-4-yl)-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C28H37N5O3
|
1
|
| 1 |
IC50 = 7.5 nM
|
|
|
|
CP0534129
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-(2-methylpropyl)urea
Show/Hide
|
C20H30N4O3
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0267445
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-piperidin-4-ylurea
Show/Hide
|
C21H31N5O3
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0365713
|
1-cyclobutyl-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]thiourea
Show/Hide
|
C20H28N4O2S
|
1
|
| 1 |
IC50 = 8.6 nM
|
|
|
|
CP0236702
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-(pyridin-3-ylmethyl)urea
Show/Hide
|
C22H27N5O3
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0557731
|
1-(3,4-dimethoxyphenyl)-1-ethyl-3-[3-(5-methylimidazol-1-yl)propyl]thiourea
Show/Hide
|
C18H26N4O2S
|
1
|
| 1 |
IC50 = 8.8 nM
|
|
|
|
CP0492169
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-(pyridin-4-ylmethyl)urea
Show/Hide
|
C22H27N5O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0485797
|
1-(3,4-dimethoxyphenyl)-1-methyl-3-[3-(5-methylimidazol-1-yl)propyl]thiourea
Show/Hide
|
C17H24N4O2S
|
1
|
| 1 |
IC50 = 12.4 nM
|
|
|
|
CP0492193
|
1-[(4-chlorophenyl)methyl]-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C23H27ClN4O3
|
1
|
| 1 |
IC50 = 12.5 nM
|
|
|
|
CP0492171
|
1-[(3-chlorophenyl)methyl]-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C23H27ClN4O3
|
1
|
| 1 |
IC50 = 12.9 nM
|
|
|
|
CP0416967
|
1-benzyl-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C23H28N4O3
|
1
|
| 1 |
IC50 = 13.3 nM
|
|
|
|
CP0539277
|
1-(3,4-dimethoxyphenyl)-1-[1-[(4-fluorophenyl)methyl]piperidin-4-yl]-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C28H36FN5O3
|
1
|
| 1 |
IC50 = 13.6 nM
|
|
|
|
CP0544040
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-(2-piperazin-1-ylethyl)urea
Show/Hide
|
C22H34N6O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0557730
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-(1-phenylpiperidin-4-yl)urea
Show/Hide
|
C27H35N5O3
|
1
|
| 1 |
IC50 = 16.4 nM
|
|
|
|
CP0533267
|
2-fluoro-5-[2-[4-(4-methyl-1,2,4-triazol-3-yl)piperidin-1-yl]pyridin-3-yl]pyridine
Show/Hide
|
C18H19FN6
|
1
|
| 1 |
IC50 = 16.7 nM
|
|
|
|
CP0477451
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-propan-2-ylurea
Show/Hide
|
C19H28N4O3
|
1
|
| 1 |
IC50 = 17.5 nM
|
|
|
|
CP0477450
|
1-[(2-aminopyridin-4-yl)methyl]-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C22H28N6O3
|
1
|
| 1 |
IC50 = 17.6 nM
|
|
|
|
CP0565233
|
1-cyclopentyl-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C21H30N4O3
|
1
|
| 1 |
IC50 = 19.4 nM
|
|
|
|
CP0475477
|
1-(3,4-dimethoxyphenyl)-1-[(3-fluorophenyl)methyl]-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C23H27FN4O3
|
1
|
| 1 |
IC50 = 20.5 nM
|
|
|
|
CP0538596
|
1-(3,4-dimethoxyphenyl)-N-[3-(5-methylimidazol-1-yl)propyl]cyclopentane-1-carboxamide
Show/Hide
|
C21H29N3O3
|
1
|
| 1 |
IC50 = 22.9 nM
|
|
|
|
CP0477448
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-[1-(pyridin-3-ylmethyl)piperidin-4-yl]urea
Show/Hide
|
C27H36N6O3
|
1
|
| 1 |
IC50 = 23.3 nM
|
|
|
|
CP0533265
|
1-[(6-aminopyridin-3-yl)methyl]-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C22H28N6O3
|
1
|
| 1 |
IC50 = 23.5 nM
|
|
|
|
CP0492191
|
1-(3,4-dimethoxyphenyl)-N-[3-(5-methylimidazol-1-yl)propyl]cyclopropane-1-carboxamide
Show/Hide
|
C19H25N3O3
|
1
|
| 1 |
IC50 = 24.3 nM
|
|
|
|
CP0536381
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-(2-morpholin-4-ylethyl)urea
Show/Hide
|
C22H33N5O4
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0538597
|
1-cyclopropyl-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]thiourea
Show/Hide
|
C19H26N4O2S
|
1
|
| 1 |
IC50 = 25.6 nM
|
|
|
|
CP0538581
|
1-cyclobutyl-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C20H28N4O3
|
1
|
| 1 |
IC50 = 26.5 nM
|
|
|
|
CP0416968
|
1-(3,4-dimethoxyphenyl)-1-ethyl-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C18H26N4O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0206338
|
US8486940, 13
Show/Hide
|
C19H20N4O2
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0370024
|
1-(3,4-Dimethoxyphenyl)-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)thiourea
Show/Hide
|
C16H22N4O2S
|
1
|
| 1 |
IC50 = 29.2 nM
|
|
|
|
CP0521370
|
1-(3,4-dimethoxyphenyl)-1-[(6-fluoropyridin-3-yl)methyl]-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C22H26FN5O3
|
1
|
| 1 |
IC50 = 30.6 nM
|
|
|
|
CP0521369
|
1-[(6-chloropyridin-3-yl)methyl]-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C22H26ClN5O3
|
1
|
| 1 |
IC50 = 32.5 nM
|
|
|
|
CP0550855
|
1-[2-(2-aminopyridin-4-yl)ethyl]-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C23H30N6O3
|
1
|
| 1 |
IC50 = 36.9 nM
|
|
|
|
CP0402293
|
1-(3,4-dimethoxyphenyl)-N-[3-(5-methylimidazol-1-yl)propyl]cyclobutane-1-carboxamide
Show/Hide
|
C20H27N3O3
|
1
|
| 1 |
IC50 = 37.1 nM
|
|
|
|
CP0557764
|
1-cyclopropyl-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C19H26N4O3
|
1
|
| 1 |
IC50 = 38.5 nM
|
|
|
|
CP0533264
|
2-(3,4-dimethoxyphenyl)-N-[3-(5-methylimidazol-1-yl)propyl]-3-phenylpropanamide
Show/Hide
|
C24H29N3O3
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0251885
|
US9181233, 67
Show/Hide
|
C18H16N4O2S2
|
1
|
| 1 |
IC50 = 47.9 nM
|
|
|
|
CP0475476
|
1-(1-acetylpiperidin-4-yl)-1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C23H33N5O4
|
1
|
| 1 |
IC50 = 53.9 nM
|
|
|
|
CP0492168
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-(1,3-oxazol-2-yl)urea
Show/Hide
|
C19H23N5O4
|
1
|
| 1 |
IC50 = 69.6 nM
|
|
|
|
CP0544073
|
2-(3,4-dimethoxyphenyl)-2-methyl-N-[3-(5-methylimidazol-1-yl)propyl]propanamide
Show/Hide
|
C19H27N3O3
|
1
|
| 1 |
IC50 = 77.3 nM
|
|
|
|
CP0538595
|
1-(3,4-dimethoxyphenyl)-N-[3-(5-methylimidazol-1-yl)propyl]cyclohexane-1-carboxamide
Show/Hide
|
C22H31N3O3
|
1
|
| 1 |
IC50 = 77.5 nM
|
|
|
|
CP0412327
|
1-(3,4-dimethoxyphenyl)-1-methyl-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C17H24N4O3
|
1
|
| 1 |
IC50 = 78.7 nM
|
|
|
|
CP0554008
|
1-(3,4-dimethoxyphenyl)-1-(1-ethylpiperidin-4-yl)-3-[3-(5-methylimidazol-1-yl)propyl]urea
Show/Hide
|
C23H35N5O3
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0416966
|
2-(3,4-dimethoxyphenyl)-N-[3-(5-methylimidazol-1-yl)propyl]-3-pyridin-3-ylpropanamide
Show/Hide
|
C23H28N4O3
|
1
|
| 1 |
IC50 = 81.6 nM
|
|
|
|
CP0477449
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-phenylurea
Show/Hide
|
C22H26N4O3
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0519827
|
1-(3,4-dimethoxyphenyl)-3-[3-(5-methylimidazol-1-yl)propyl]-1-(1,3-thiazol-2-yl)urea
Show/Hide
|
C19H23N5O3S
|
1
|
| 1 |
IC50 = 98.8 nM
|
|
|
|
CP0402295
|
2-(3,4-dimethoxyphenyl)-N-[3-(5-methylimidazol-1-yl)propyl]propanamide
Show/Hide
|
C18H25N3O3
|
1
|
| 1 |
IC50 = 112 nM
|
|
|
|
CP0416941
|
2-(4-fluorophenyl)-N-[3-(4-methylimidazol-1-yl)propyl]aniline
Show/Hide
|
C19H20FN3
|
1
|
| 1 |
IC50 = 118 nM
|
|
|
|
CP0477452
|
US9512082, 1
Show/Hide
|
C16H22N4O3
|
1
|
| 1 |
IC50 = 162 nM
|
|
|
|
CP0544074
|
2-(3,4-dimethoxyphenyl)-N-[3-(5-methylimidazol-1-yl)propyl]acetamide
Show/Hide
|
C17H23N3O3
|
1
|
| 1 |
IC50 = 183 nM
|
|
|
