Brief Information of the Cell Line and Protein
Cell Line ID: CL000012 , Sf21
 Cell Line Info 
Synonyms
SF21
Sf-21
SF-21
IPLB-SF-21-AE
IPLB-Sf21-AE
IPLB-SF21-AE
IPLB-SF 21AE
IPLB-Sf21AE
IPLB-SF21AE
IPLB-SF-21
IPLB-Sf-21
IPLB-SF 21
IPLB-Sf21
IPLB-SF21
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID
CVCL_0518
Protein ID: PT01290 , Substance-K receptor
 Protein Info 
Gene Name TACR2
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P21452
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000012
 Cell Line Info 
 Protein ID: PT01290
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0430312
 Compound Info 
1-[8-Isopropyl-6-(4-trifluoromethyl-phenylamino)-9H-purin-2-yl]-piperidin-4-ol
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C20H23F3N6O
  1
1
Ki = 1770 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0549533
 Compound Info 
1-[6-(4-Chloro-phenylamino)-8-isopropyl-9H-purin-2-yl]-4-methyl-piperidin-4-ol
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C20H25ClN6O
  1
1
Ki = 2100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0418835
 Compound Info 
1-[6-(4-Chloro-phenylamino)-8-isopropyl-9H-purin-2-yl]-4-phenyl-piperidin-4-ol
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C25H27ClN6O
  1
1
Ki = 2240 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0501011
 Compound Info 
2-N-(3-aminopropyl)-6-N-(4-chlorophenyl)-8-propan-2-yl-7H-purine-2,6-diamine
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C17H22ClN7
  1
1
Ki = 2550 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0491325
 Compound Info 
(8-Isopropyl-2-morpholin-4-yl-9H-purin-6-yl)-(4-trifluoromethyl-phenyl)-amine
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C19H21F3N6O
  1
1
Ki = 2850 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0532015
 Compound Info 
(4-Chloro-phenyl)-(8-isopropyl-2-morpholin-4-yl-9H-purin-6-yl)-amine
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C18H21ClN6O
  1
1
Ki = 3070 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0420749
 Compound Info 
(4-Chloro-phenyl)-[2-(4,4-dimethoxy-piperidin-1-yl)-8-isopropyl-9H-purin-6-yl]-amine
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C21H27ClN6O2
  1
1
Ki = 3440 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0526676
 Compound Info 
6-N-(4-chlorophenyl)-8-propan-2-yl-2-N-propyl-7H-purine-2,6-diamine
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C17H21ClN6
  1
1
Ki = 3490 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0504758
 Compound Info 
(4-Chloro-phenyl)-[2-(1,4-dioxa-8-aza-spiro[4.5]dec-8-yl)-8-isopropyl-9H-purin-6-yl]-amine
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C21H25ClN6O2
  1
1
Ki = 4360 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0480998
 Compound Info 
2-N-benzyl-6-N-(4-chlorophenyl)-8-propan-2-yl-7H-purine-2,6-diamine
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C21H21ClN6
  1
1
Ki = 5580 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0509459
 Compound Info 
1-[6-(4-Chloro-phenylamino)-8-isopropyl-9H-purin-2-yl]-piperidin-4-one
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C19H21ClN6O
  1
1
Ki = 5890 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS