N-[1-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]pyrrolo[3,2-b]pyridin-6-yl]acetamide

N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methylphenyl]acetamide

N-(5-(3-cyano-7-(oxetan-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-4-fluoro-2-methylphenyl)acetamide

N-[5-[[3-cyano-7-[[1-(2-morpholinoethyl)pyrazol-3-yl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methyl-phenyl]acetamide

N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-cyclopropylphenyl]acetamide

N-(5-(3-Cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-4-fluoro-2-methylphenyl)acetamide

N-(5-(3-cyano-7-(oxetan-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-methylphenyl)acetamide

N-(5-(3-Cyano-7-(1-methyl-1H-imidazol-4-ylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-methylphenyl)acetamide

N-(5-(3-cyano-7-(1-(2-(dimethylamino)ethyl)-1H-pyrazol-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-methylphenyl)acetamide

N-(5-(3-Cyano-7-(1-methyl-1H-pyrazol-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-methylphenyl)acetamide

N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-isopropyl-phenyl]acetamide

N-[5-[[3-cyano-7-(oxetan-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-cyclopropyl-4-fluorophenyl]acetamide

N-(5-(3-cyano-7-(oxetan-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-chlorophenyl)acetamide

N-[2-Chloro-5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]phenyl]acetamide

N-[5-[[3-cyano-7-(cyclobutylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-4-fluoro-2-methylphenyl]acetamide

N-[5-[[3-cyano-7-[[1-(2-pyrrolidin-1-ylethyl)imidazol-4-yl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methyl-phenyl]acetamide

N-[5-[[3-cyano-7-[[1-(2-dimethylaminoethyl)imidazol-4-yl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methyl-phenyl]acetamide

N-[5-[[3-cyano-7-[[1-(2-pyrrolidin-1-ylethyl)pyrazol-3-yl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methyl-phenyl]acetamide

N-[5-[[3-cyano-7-[[1-(2-hydroxyethyl)imidazol-4-yl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methylphenyl]acetamide

N-[5-[[3-cyano-7-(cyclobutylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methyl-phenyl]acetamide

N-(5-(3-Cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-methylpyridin-3-yl)acetamide

N-(5-(3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-cyclopropyl-4-fluorophenyl)acetamide

N-[2-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-5-methyl-4-pyridyl]acetamide

N-(5-(3-cyano-7-(oxetan-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-cyclopropylphenyl)acetamide

N-[5-[[3-cyano-7-[[1-(2-morpholinoethyl)imidazol-4-yl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methyl-phenyl]acetamide

N-(5-(3-cyano-7-(1-(2-hydroxyethyl)-1H-pyrazol-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-methylphenyl)acetamide

N-[2-[2-aminoethyl(methyl)amino]-5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]phenyl]acetamide

N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-[2-(dimethylamino)ethyl-methylamino]phenyl]acetamide

N-[2-[(3R)-3-aminopyrrolidin-1-yl]-5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]phenyl]acetamide

N-[2-[2-aminoethyl(ethyl)amino]-5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]phenyl]acetamide

N-[2-[(3S)-3-aminopyrrolidin-1-yl]-5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]phenyl]acetamide

N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-(3-hydroxypropylamino)phenyl]acetamide

N-[2-[[(2S)-2-aminopropyl]-methylamino]-5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]phenyl]acetamide

N-[2-[(3S)-3-aminopiperidin-1-yl]-5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]phenyl]acetamide

N-[2-[[(2R)-2-aminopropyl]-methylamino]-5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]phenyl]acetamide

N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-[methyl(2-morpholin-4-ylethyl)amino]phenyl]acetamide

5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid

4-[6-[6-(propan-2-ylamino)indol-1-yl]pyrazin-2-yl]benzoic acid

3-[5-acetamido-3-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indol-1-yl]propanoic acid

N-[1-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-2,3-dihydroindol-6-yl]acetamide

N-[1-[3-cyano-7-(oxetan-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]acetamide

N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-[(3R)-3-(dimethylamino)piperidin-1-yl]phenyl]acetamide

N-[2-[(3R)-3-aminopiperidin-1-yl]-5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]phenyl]acetamide

4-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]benzoic acid

3-fluoro-4-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]benzoic acid

5-[(1-acetyl-2,3-dihydroindol-6-yl)amino]-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]phenyl]acetamide

N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-[3-(dimethylamino)propyl-methylamino]phenyl]acetamide

7-(cyclopropylamino)-5-[6-(methylsulfonylmethyl)indol-1-yl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile

6-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]pyridine-3-carboxylic acid

2-fluoro-4-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]benzoic acid

N-[3-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]phenyl]acetamide

N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-[2-(diethylamino)ethyl-methylamino]phenyl]acetamide

N-[1-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]acetamide

N-[1-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]-N-methylacetamide

N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-[2-(3,3-difluoroazetidin-1-yl)ethyl-methylamino]phenyl]acetamide

3-chloro-4-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]benzoic acid

N-[1-[3-cyano-7-(3-pyrrolidin-1-ylpropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]acetamide

N-[1-[3-cyano-7-[(1-methylpyrazol-3-yl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]acetamide

N-[1-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indazol-6-yl]acetamide

4-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]thiophene-2-carboxylic acid

N-[1-[3-cyano-7-[3-(dimethylamino)propylamino]pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]acetamide

N-[1-[3-cyano-7-(4-hydroxybutylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]acetamide

N-[1-[3-cyano-7-(2-morpholin-4-ylethylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]acetamide

N-[1-[3-cyano-7-(2-pyrrolidin-1-ylethylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indol-6-yl]acetamide

N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-(4-methylpiperazin-1-yl)phenyl]acetamide

5-(4-methoxyphenyl)-7-[(1-methylpyrazol-3-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carbonitrile

7-amino-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

5-[2-[4-(dimethylcarbamoyl)anilino]-4-methoxypyrimidin-5-yl]thiophene-2-carboxylic acid

7-(cyclopropylamino)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

N-[1-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-5-methylindol-6-yl]acetamide

7-amino-5-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carbonitrile

5-[2-[4-(dimethylcarbamoyl)anilino]-4-methoxypyrimidin-5-yl]thiophene-3-carboxylic acid

3-methoxy-4-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]benzoic acid

7-(cyclopropylamino)-5-[6-(hydroxymethyl)indol-1-yl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile

N-propan-2-yl-1-[6-[4-(2H-tetrazol-5-yl)phenyl]pyrazin-2-yl]indazol-6-amine

7-amino-5-phenylpyrazolo[1,5-a]pyrimidine-3-carbonitrile

N-[1-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-3,4-dihydro-2H-quinolin-7-yl]acetamide

7-(cyclopropylamino)-5-(4-methoxypyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

N-[4-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-2,3-dihydro-1,4-benzoxazin-6-yl]acetamide

5-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]pyridine-2-carboxylic acid

1-[6-[4-(aminomethyl)phenyl]pyrazin-2-yl]-N-propan-2-ylindazol-6-amine

N-methylsulfonyl-4-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]benzamide

4-[2-[4-(dimethylcarbamoyl)anilino]-4-methoxypyrimidin-5-yl]thiophene-2-carboxylic acid

7-amino-5-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

7-(cyclopropylamino)-5-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carbonitrile

2-methyl-4-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]benzoic acid

4-[2-[4-(dimethylcarbamoyl)anilino]pyrimidin-5-yl]benzoic acid

2-acetamido-N-[1-(6-cyanopyrazin-2-yl)indazol-6-yl]acetamide

5-[2-[4-(dimethylcarbamoyl)anilino]-4-methoxypyrimidin-5-yl]thiophene-2-carboxamide

3-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]benzoic acid

N-[3-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-1H-indol-5-yl]acetamide

N-[3-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-1-methylindol-5-yl]acetamide

N-[3-[1-(6-cyanopyrazin-2-yl)indazol-6-yl]phenyl]acetamide

4-acetamido-N-[1-(6-cyanopyrazin-2-yl)indazol-6-yl]butanamide

methyl 3-[5-acetamido-3-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]indol-1-yl]propanoate

N-[[4-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]phenyl]methyl]acetamide

N'-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]propane-1,3-diamine

2,2,2-trifluoro-1-[4-[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]phenyl]ethanol

N-[3-[[6-[6-(propan-2-ylamino)indazol-1-yl]pyrazin-2-yl]amino]propyl]acetamide

3-acetamido-N-[1-(6-cyanopyrazin-2-yl)indazol-6-yl]propanamide

[3-[4-[(4-cyclopropylphenyl)methoxy]-3-methoxyphenyl]azetidin-1-yl]-[4-[[(2S)-2,3-dihydroxypropoxy]methyl]pyridin-2-yl]methanone

N-[3-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-1-(2-hydroxyethyl)indol-5-yl]acetamide

N-[3-[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]-1-(3-hydroxypropyl)indol-5-yl]acetamide