Brief Information of the Cell Line and Protein
Cell Line ID: CL000012 , Sf21
 Cell Line Info 
Synonyms
SF21
Sf-21
SF-21
IPLB-SF-21-AE
IPLB-Sf21-AE
IPLB-SF21-AE
IPLB-SF 21AE
IPLB-Sf21AE
IPLB-SF21AE
IPLB-SF-21
IPLB-Sf-21
IPLB-SF 21
IPLB-Sf21
IPLB-SF21
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID
CVCL_0518
Protein ID: PT01132 , Orexin receptor type 2
 Protein Info 
Gene Name HCRTR2
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID O43614
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000012
 Cell Line Info 
 Protein ID: PT01132
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0068575
 Compound Info 
US8569311, E-5
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C24H25FN4O2
  1
1
Ki = 0.1995 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0058379
 Compound Info 
E-2006
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C22H20F2N4O2
  1
1
Ki = 0.5012 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0174640
 Compound Info 
US9000029, 26
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C20H24N2O4S
  1
1
Ki = 0.631 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0326222
 Compound Info 
[(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
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C23H23ClN6O2
  1
1
Ki = 0.7943 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0533206
 Compound Info 
US11040966, Example 5.36
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C23H23ClN6O2
  1
1
Ki = 1.259 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0077068
 Compound Info 
2-(5,6-dimethoxypyridin-3-yl)-1,1-dioxo-4-[(2,4,6-trifluorophenyl)methyl]pyrido[2,3-e][1,2,4]thiadiazin-3-one
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C20H15F3N4O5S
  1
1
Ki = 5.012 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0443937
 Compound Info 
2-[1-(benzenesulfonyl)-1,8-diazaspiro[4.5]decan-8-yl]-1,3-benzoxazole
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C21H23N3O3S
  1
1
Ki = 15.85 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0560778
 Compound Info 
2-(5-methylsulfonylpyridin-3-yl)-1,1-dioxo-4-[(2,4,6-trifluorophenyl)methyl]pyrido[2,3-e][1,2,4]thiadiazin-3-one
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C19H13F3N4O5S2
  1
1
Ki = 50.12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0199148
 Compound Info 
[(2S,5S)-2-[[(5-bromopyridin-2-yl)amino]methyl]-5-methylpiperidin-1-yl]-(3-fluoro-2-methoxyphenyl)methanone
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C20H23BrFN3O2
  1
1
Ki = 63.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0044395
 Compound Info 
1-(2-methyl-1,3-benzoxazol-6-yl)-3-(1,5-naphthyridin-4-yl)urea
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C17H13N5O2
  1
1
Ki = 630.96 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0053196
 Compound Info 
1-(6,8-difluoro-2-methylquinolin-4-yl)-3-[4-(dimethylamino)phenyl]urea
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C19H18F2N4O
  1
1
Ki = 794.33 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0086435
 Compound Info 
N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonylamino]-N-(pyridin-3-ylmethyl)acetamide
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C23H26N4O4S
  1
1
Ki = 1000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS