Duvelisib

2-(difluoromethyl)-1-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-1H-benzimidazole

N-[2-methoxy-5-[7-[[(2R)-4-(oxetan-3-yl)morpholin-2-yl]methoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]methanesulfonamide

N-[2-[4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]methyl]-2-fluorophenyl]pyridin-4-yl]-2-methoxy-5-morpholin-4-ylpyridine-3-sulfonamide

2-methoxy-N-[2-methoxy-5-[7-[[(2S)-4-(oxetan-3-yl)morpholin-2-yl]methoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]ethanesulfonamide

N-[[(2R,6S)-2,6-dimethyloxan-4-yl]methyl]-6-[5-(methanesulfonamido)-6-methoxypyridin-3-yl]-1,3-dihydro-2-benzofuran-4-carboxamide

2-methoxy-N-[2-methoxy-5-[7-[[(2R)-4-(oxetan-3-yl)morpholin-2-yl]methoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]ethanesulfonamide

N-[5-[7-[[(2R)-4-(2-hydroxy-2-methylpropyl)morpholin-2-yl]methoxy]-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]methanesulfonamide

1-cyano-N-[5-[7-[2-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]methanesulfonamide

N-[2-methoxy-5-[7-[[(2R)-4-methylmorpholin-2-yl]methoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]methanesulfonamide

N-[2-methoxy-5-[7-[[(2R)-4-(2-methoxyethyl)morpholin-2-yl]methoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]methanesulfonamide

N-[5-[4-[2-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydrofuro[3,4-c]pyridin-6-yl]-2-methoxypyridin-3-yl]methanesulfonamide

N-[2-methoxy-5-[7-(2-morpholin-4-ylethoxy)-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]methanesulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-N-[5-[4-[[(2R,6S)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]pyridin-3-yl]-2-methoxypyridine-3-sulfonamide

N-[5-[7-[2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]methanesulfonamide

N-[5-[7-[[(2R)-4-cyclobutylmorpholin-2-yl]methoxy]-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]-2-methoxyethanesulfonamide

N-[2-methoxy-5-[7-[[(2S)-4-methylmorpholin-2-yl]methoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]methanesulfonamide

N-[5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxypyridin-3-yl]benzenesulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-[5-[5-(piperidin-1-ylmethyl)thiophen-2-yl]pyridin-3-yl]pyridine-3-sulfonamide

4-[4-(2-methylbenzimidazol-1-yl)-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine

N-[5-[7-[[(2R)-4-(2-hydroxy-2-methylpropyl)morpholin-2-yl]methoxy]-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]-2-methoxyethanesulfonamide

N-[2-[2-fluoro-4-[(4-propan-2-ylpiperazin-1-yl)methyl]phenyl]pyridin-4-yl]-2-methoxy-5-morpholin-4-ylpyridine-3-sulfonamide

N-[2-[4-[(4-tert-butylpiperazin-1-yl)methyl]-2-fluorophenyl]pyridin-4-yl]-2-methoxy-5-morpholin-4-ylpyridine-3-sulfonamide

N-(2-(2,3-difluoro-4-((4-isopropylpiperazin-1-yl)methyl)phenyl)pyridin-4-yl)-2-methoxy-5-morpholinopyridine-3-sulfonamide hemic formic acid salt

2-methoxy-N-[2-methoxy-5-[7-[[(2R)-4-propan-2-ylmorpholin-2-yl]methoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]ethanesulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-[5-[4-[(4-propan-2-ylpiperazin-1-yl)methyl]phenyl]pyridin-3-yl]pyridine-3-sulfonamide

N-[5-[2-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]pyridin-3-yl]-2-methoxy-5-morpholin-4-ylpyridine-3-sulfonamide

N-[5-[2-fluoro-4-[(4-propan-2-ylpiperazin-1-yl)methyl]phenyl]pyridin-3-yl]-2-methoxy-5-morpholin-4-ylpyridine-3-sulfonamide

4-[4-morpholin-4-yl-6-(2-propan-2-ylbenzimidazol-1-yl)-1,3,5-triazin-2-yl]morpholine

N-[6-[5-(methanesulfonamido)-6-methoxypyridin-3-yl]-1,3-dihydro-2-benzofuran-4-yl]-2-(oxan-4-yl)acetamide

N-[5-[5-[2-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]ethoxy]-3,4-dihydro-1H-isochromen-7-yl]-2-methoxypyridin-3-yl]methanesulfonamide

N-[5-[7-[2-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]ethylamino]-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]methanesulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-[5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]pyridin-3-yl]pyridine-3-sulfonamide

N-[2-[2-fluoro-4-[[4-(2-hydroxypropan-2-yl)piperidin-1-yl]methyl]phenyl]pyridin-4-yl]-2-methoxy-5-morpholin-4-ylpyridine-3-sulfonamide

N-[5-[(3R)-7-[2-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]ethoxy]-3-methyl-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]methanesulfonamide

N-[5-[5-[2-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]ethoxy]-3,4-dihydro-1H-isochromen-7-yl]-2-methoxypyridin-3-yl]-2-methoxyethanesulfonamide

N-[5-[7-[3-[(2S,6R)-2,6-dimethylmorpholin-4-yl]propyl]-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]methanesulfonamide

N-[5-[7-[2-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]methanesulfonamide

N-[2-[3-fluoro-4-[(4-propan-2-ylpiperazin-1-yl)methyl]phenyl]pyridin-4-yl]-2-methoxy-5-morpholin-4-ylpyridine-3-sulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-(2-methylpyridin-4-yl)pyridine-3-sulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-[5-[3-(pyrrolidin-1-ylmethyl)phenyl]pyridin-3-yl]pyridine-3-sulfonamide

N-(2-(4-((4-tert-butylpiperazin-1-yl)methyl)phenyl)pyridin-4-yl)-2-methoxy-5-morpholinopyridine-3-sulfonamide hemi formic acid salt

N-[5-[6-fluoro-7-[2-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]methanesulfonamide

N-[5-[7-[2-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]-2-methoxyethanesulfonamide

N-[5-[7-[(2R)-1-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]propan-2-yl]oxy-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]-2-methoxyethanesulfonamide

N-[2-methoxy-5-[7-(3-morpholin-4-yl-2-oxopropyl)-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]methanesulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-[5-[6-[(4-propan-2-ylpiperazin-1-yl)methyl]pyridin-3-yl]pyridin-3-yl]pyridine-3-sulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-[5-[4-[[(3R,5S)-3,4,5-trimethylpiperazin-1-yl]methyl]phenyl]pyridin-3-yl]pyridine-3-sulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-(5-methylpyridin-3-yl)pyridine-3-sulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-[5-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)pyridin-3-yl]pyridine-3-sulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-N-[5-[3-[(2R,6S)-2,6-dimethylmorpholin-4-yl]prop-1-ynyl]pyridin-3-yl]-2-methoxypyridine-3-sulfonamide

2-methoxy-5-morpholin-4-yl-N-[2-[4-[(4-propan-2-ylpiperazin-1-yl)methyl]phenyl]pyridin-4-yl]pyridine-3-sulfonamide

2-[(2S,6R)-2,6-dimethyloxan-4-yl]-N-[6-[5-(methanesulfonamido)-6-methoxypyridin-3-yl]-1,3-dihydro-2-benzofuran-4-yl]acetamide

N-[6-[5-(methanesulfonamido)-6-methoxypyridin-3-yl]-1,3-dihydro-2-benzofuran-4-yl]-2-(4-methylpiperazin-1-yl)acetamide

N-[5-[7-[(2R)-2-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]propoxy]-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]-2-methoxyethanesulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-[5-[3-(piperidin-1-ylmethyl)phenyl]pyridin-3-yl]pyridine-3-sulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-[5-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pyridin-3-yl]pyridine-3-sulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-N-[5-[2-[(dimethylamino)methyl]cyclopropyl]pyridin-3-yl]-2-methoxypyridine-3-sulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-[5-[4-(piperazin-1-ylmethyl)phenyl]pyridin-3-yl]pyridine-3-sulfonamide

2-methoxy-5-morpholin-4-yl-N-[5-[4-[(4-propan-2-ylpiperazin-1-yl)methyl]phenyl]pyridin-3-yl]pyridine-3-sulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-phenylpyridine-3-sulfonamide

2,4-diamino-6-[(2S,5S)-2-[3-(3-fluorophenyl)-5-(5-methoxypyridin-3-yl)-4-oxoquinazolin-2-yl]-5-methylpyrrolidin-1-yl]pyrimidine-5-carbonitrile

4-[4-(6-methoxy-2-propan-2-ylbenzimidazol-1-yl)-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine

4-[4-(5-methoxy-2-methylbenzimidazol-1-yl)-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine

4-[4-(5-methoxy-2-propan-2-ylbenzimidazol-1-yl)-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine

4-[4-[2-(difluoromethyl)-6-methoxybenzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine

4-[4-[2-(difluoromethyl)-5-methoxybenzimidazol-1-yl]-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine

4-[4-(6-methoxy-2-methylbenzimidazol-1-yl)-6-morpholin-4-yl-1,3,5-triazin-2-yl]morpholine

N-[5-[7-[(2S)-2-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]propoxy]-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]-2-methoxyethanesulfonamide

N-[6-[5-(methanesulfonamido)-6-methoxypyridin-3-yl]-1,3-dihydro-2-benzofuran-4-yl]-2-(4-propan-2-ylpiperazin-1-yl)acetamide

N-[5-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]pyridin-3-yl]-2-methoxy-5-morpholin-4-ylpyridine-3-sulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-N-[5-[4-[(dimethylamino)methyl]phenyl]pyridin-3-yl]-2-methoxypyridine-3-sulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-[5-[4-(pyrrolidin-1-ylmethyl)phenyl]pyridin-3-yl]pyridine-3-sulfonamide

2-Methoxy-5-morpholino-N-(5-(4-(pyrrolidin-1-ylmethyl)phenyl)pyridin-3-yl)pyridine-3-sulfonamide formic acid salt

N-[2-methoxy-5-[4-[[(2R)-4-methylmorpholin-2-yl]methoxy]-5,7-dihydrofuro[3,4-b]pyridin-2-yl]pyridin-3-yl]methanesulfonamide

2-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]-N-[6-[5-(methanesulfonamido)-6-methoxypyridin-3-yl]-1,3-dihydro-2-benzofuran-4-yl]acetamide

N-[6-[5-(methanesulfonamido)-6-methoxypyridin-3-yl]-1,3-dihydro-2-benzofuran-4-yl]-1-methylpiperidine-3-carboxamide

N-[5-[7-[(2S)-1-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]propan-2-yl]oxy-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]-2-methoxyethanesulfonamide

2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-N-[6-[5-(methanesulfonamido)-6-methoxypyridin-3-yl]-1,3-dihydro-2-benzofuran-4-yl]acetamide

2,4-diamino-6-[(2S,5S)-2-(5-chloro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-5-methylpyrrolidin-1-yl]pyrimidine-5-carbonitrile

2,4-diamino-6-[(2S,5S)-2-[5-chloro-3-(3-fluorophenyl)-4-oxoquinazolin-2-yl]-5-methylpyrrolidin-1-yl]pyrimidine-5-carbonitrile

N-[5-[4-fluoro-7-[2-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]methanesulfonamide

5-(3,6-dihydro-2H-pyran-4-yl)-2-methoxy-N-[5-[3-(4-propan-2-ylpiperazin-1-yl)prop-1-ynyl]pyridin-3-yl]pyridine-3-sulfonamide

2,4-diamino-6-[(2S,5S)-2-(6,8-difluoro-4-oxo-3-pyridin-3-ylquinazolin-2-yl)-5-methylpyrrolidin-1-yl]pyrimidine-5-carbonitrile

N-[5-[4-chloro-7-[2-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]-2-methoxypyridin-3-yl]methanesulfonamide

2-methoxy-5-morpholin-4-yl-N-[5-[3-(4-propan-2-ylpiperazin-1-yl)prop-1-ynyl]pyridin-3-yl]pyridine-3-sulfonamide

5-[7-chloro-2-[(4-methylsulfonylpiperazin-1-yl)methyl]-4-morpholin-4-ylpyrazolo[1,5-a]pyrazin-6-yl]pyrimidin-2-amine

5-[2-[(4-methylsulfonylpiperazin-1-yl)methyl]-8-morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyrazin-6-yl]pyrimidin-2-amine

5-[6-[(4-methylsulfonylpiperazin-1-yl)methyl]-4-morpholin-4-ylimidazo[2,1-f][1,2,4]triazin-2-yl]pyrimidin-2-amine

5-[5-chloro-2-[(4-methylsulfonylpiperazin-1-yl)methyl]-8-morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyrazin-6-yl]pyrimidin-2-amine

5-[2-[(4-methylsulfonylpiperazin-1-yl)methyl]-4-morpholin-4-ylpyrazolo[1,5-a]pyrazin-6-yl]pyrimidin-2-amine

5-[2-[(4-methylsulfonylpiperazin-1-yl)methyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl]pyrimidin-2-amine