Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT06250 , Potassium voltage-gated channel subfamily H member 3
Gene Name KCNH3
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID Q9ULD8
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT06250
 
Compound ID Compound Name Compound Formula
CP0967414
N2-(4-fluorophenyl)-N4-(furan-2-ylmethyl)-N6-phenyl-1,3,5-triazine-2,4,6-triamine hydrochloride
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C20H18ClFN6O
 1
1
IC50 = 47 nM
   TI
   LI
   LO
   TS
CP0901766
N2-(furan-2-ylmethyl)-N4,N6-diphenyl-1,3,5-triazine-2,4,6-triamine
   Show/Hide
C20H18N6O
 1
1
IC50 = 52 nM
   TI
   LI
   LO
   TS
CP0942275
N,N'-bis(4-fluorophenyl)-N''-(pyrimidin-4-ylmethyl)-1,3,5-triazine-2,4,6-triamine
   Show/Hide
C20H16F2N8
 1
1
IC50 = 58 nM
   TI
   LI
   LO
   TS
CP0864423
N,N'-bis(4-fluorophenyl)-N''-(pyrimidin-2-ylmethyl)-1,3,5-triazine-2,4,6-triamine
   Show/Hide
C20H16F2N8
 1
1
IC50 = 65 nM
   TI
   LI
   LO
   TS
CP0915638
N2,N4-bis(4-fluorophenyl)-N6-(furan-2-ylmethyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C20H17ClF2N6O
 1
1
IC50 = 73 nM
   TI
   LI
   LO
   TS
CP0866132
N-(4-fluorophenyl)-N'-phenyl-N''-(pyrimidin-2-ylmethyl)-1,3,5-triazine-2,4,6-triamine
   Show/Hide
C20H17FN8
 1
1
IC50 = 77 nM
   TI
   LI
   LO
   TS
CP0915633
N2-((3-fluoropyridin-4-yl)methyl)-N4,N6-diphenyl-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C21H19ClFN7
 1
1
IC50 = 79 nM
   TI
   LI
   LO
   TS
CP0913905
N,N'-diphenyl-N''-(4-pyridylmethyl)-1,3,5-triazine-2,4,6-triamine
   Show/Hide
C21H19N7
 1
1
IC50 = 84 nM
   TI
   LI
   LO
   TS
CP0963865
N2-(4-fluorophenyl)-N4-((2-fluoropyridin-4-yl)methyl)-N6-phenyl-1,3,5-triazine-2,4,6-triamine N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C21H18ClF2N7
 1
1
IC50 = 85 nM
   TI
   LI
   LO
   TS
CP0911471
N-(4-fluorophenyl)-N'-[(2-fluoro-4-pyridyl)methyl]-N'-phenyl-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C21H18ClF2N7
 1
1
IC50 = 85 nM
   TI
   LI
   LO
   TS
CP0930887
N-(4-fluorophenyl)-N'-(4-methoxyphenyl)-N''-(pyrimidin-2-ylmethyl)-1,3,5-triazine-2,4,6-triamine
   Show/Hide
C21H19FN8O
 1
1
IC50 = 92 nM
   TI
   LI
   LO
   TS
CP0919522
N2,N4-bis(4-fluorophenyl)-N6-((2-fluoropyridin-4-yl)methyl)-1,3,5-triazine-2,4,6-triamine N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C21H17ClF3N7
 1
1
IC50 = 100 nM
   TI
   LI
   LO
   TS
CP0950216
4-(4-(4-fluorophenylamino)-6-(phenylamino)-1,3,5-triazin-2-ylamino)butan-1-ol N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C19H22ClFN6O
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0960112
N2,N4-bis(4-fluorophenyl)-N6-(pyridin-4-ylmethyl)-1,3,5-triazine-2,4,6-triamine dihydrochloride
   Show/Hide
C21H19Cl2F2N7
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0902690
N2-isopropyl-N4-phenyl-N6-(4-(trifluoromethyl)phenyl)-1,3,5-triazine-2,4,6-triamine N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C19H20ClF3N6
 1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CP0962825
5-(4-(4-fluorophenylamino)-6-(phenylamino)-1,3,5-triazin-2-ylamino)pentan-1-ol N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C20H24ClFN6O
 1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CP0962538
N2-(4-fluorophenyl)-N4-((2-fluoropyridin-4-yl)methyl)-N6-(4-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C22H20ClF2N7O
 1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
CP0924062
2-(2-(4,6-bis(4-fluorophenylamino)-1,3,5-triazin-2-ylamino)ethoxy)ethanol hydrochloride
   Show/Hide
C19H21ClF2N6O2
 1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
CP0924064
N2-isopropyl-N4,N6-diphenyl-1,3,5-triazine-2,4,6-triamine
   Show/Hide
C18H20N6
 1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS
CP0888265
5-(4,6-bis(phenylamino)-1,3,5-triazin-2-ylamino)pentan-1-ol
   Show/Hide
C20H24N6O
 1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
CP0967415
2-(2-(4-(4-fluorophenylamino)-6-(phenylamino)-1,3,5-triazin-2-ylamino)ethoxy)ethanol N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C19H22ClFN6O2
 1
1
IC50 = 210 nM
   TI
   LI
   LO
   TS
CP0913897
N-(4-fluorophenyl)-N'-isopropyl-N''-phenyl-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C18H20ClFN6
 1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
CP0888302
2-(2-(4,6-bis(phenylamino)-1,3,5-triazin-2-ylamino)ethoxy)ethanol hydrochloride
   Show/Hide
C19H23ClN6O2
 1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
CP0901763
N2,N4-bis(4-fluorophenyl)-N6-isopropyl-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C18H19ClF2N6
 1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
CP0945322
N2-(4-fluorophenyl)-N4-((2-fluoropyridin-4-yl)methyl)-N6-p-tolyl-1,3,5-triazine-2,4,6-triamine N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C22H20ClF2N7
 1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
CP0967419
N2,N4-bis(4-fluorophenyl)-N6-(2-methoxyethyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C18H19ClF2N6O
 1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
CP0871232
N2-(4-fluorophenyl)-N4-(2-methoxyethyl)-N6-phenyl-1,3,5-triazine-2,4,6-triamine N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C18H20ClFN6O
 1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
CP0943868
N2-(4-fluorophenyl)-N4-((2-fluoropyridin-4-yl)methyl)-N6-(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C22H20ClF2N7O
 1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
CP0893947
5-(4,6-bis(4-fluorophenylamino)-1,3,5-triazin-2-ylamino)pentan-1-ol hydrochloride
   Show/Hide
C20H23ClF2N6O
 1
1
IC50 = 260 nM
   TI
   LI
   LO
   TS
CP0873001
N2-(2-methoxyethyl)-N4,N6-diphenyl-1,3,5-triazine-2,4,6-triamine
   Show/Hide
C18H20N6O
 1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
CP0911453
N2-(4-fluorobenzyl)-N4,N6-diphenyl-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C22H20ClFN6
 1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
CP0919521
N2-isopropyl-N4-(4-methoxyphenyl)-N6-phenyl-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C19H23ClN6O
 1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
CP0960114
N2,N4-diphenyl-N6-(2-(pyridin-4-yl)ethyl)-1,3,5-triazine-2,4,6-triamine
   Show/Hide
C22H21N7
 1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
CP0901764
N2,N4-diphenyl-N6-((tetrahydrofuran-2-yl)methyl)-1,3,5-triazine-2,4,6-triamine
   Show/Hide
C20H22N6O
 1
1
IC50 = 320 nM
   TI
   LI
   LO
   TS
CP0901760
(S)-2-(4-(4-fluorophenylamino)-6-(phenylamino)-1,3,5-triazin-2-ylamino)butan-1-ol N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C19H22ClFN6O
 1
1
IC50 = 340 nM
   TI
   LI
   LO
   TS
CP0888275
N2-(4-fluorobenzyl)-N4,N6-bis(4-fluorophenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C22H18ClF3N6
 1
1
IC50 = 350 nM
   TI
   LI
   LO
   TS
CP0899596
N2,N4-diphenyl-N6-(prop-2-ynyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C18H17ClN6
 1
1
IC50 = 360 nM
   TI
   LI
   LO
   TS
CP0864216
N2-pentyl-N4,N6-diphenyl-1,3,5-triazine-2,4,6-triamine
   Show/Hide
C20H24N6
 1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS
CP0962537
N2-benzyl-N4,N6-diphenyl-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C22H21ClN6
 1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS
CP0962826
N2-benzyl-N4,N6-bis(4-fluorophenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C22H19ClF2N6
 1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS
CP0954555
N2-isopropyl-N4,N6-bis(4-nitrophenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C18H19ClN8O4
 1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
CP0895950
N2-(2-methoxyethyl)-N4-(4-methoxyphenyl)-N6-phenyl-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C19H23ClN6O2
 1
1
IC50 = 420 nM
   TI
   LI
   LO
   TS
CP0916646
N2,N4-diphenyl-N6-(thiophen-2-ylmethyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C20H19ClN6S
 1
1
IC50 = 430 nM
   TI
   LI
   LO
   TS
CP0903658
(S)-2-(4-(4-fluorophenylamino)-6-(phenylamino)-1,3,5-triazin-2-ylamino)propan-1-ol N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C18H20ClFN6O
 1
1
IC50 = 450 nM
   TI
   LI
   LO
   TS
CP0960113
3-((4,6-bis(phenylamino)-1,3,5-triazin-2-ylamino)methyl)dihydrofuran-2(3H)-one hydrochloride
   Show/Hide
C20H21ClN6O2
 1
1
IC50 = 480 nM
   TI
   LI
   LO
   TS
CP0966784
N2,N4-bis(4-fluorophenyl)-N6-((tetrahydrofuran-2-yl)methyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C20H21ClF2N6O
 1
1
IC50 = 480 nM
   TI
   LI
   LO
   TS
CP0895947
N2-(4-chlorophenyl)-N4-isopropyl-N6-phenyl-1,3,5-triazine-2,4,6-triamine N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C18H20Cl2N6
 1
1
IC50 = 490 nM
   TI
   LI
   LO
   TS
CP0919526
N2,N4-bis(4-fluorophenyl)-N6-(thiophen-2-ylmethyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C20H17ClF2N6S
 1
1
IC50 = 490 nM
   TI
   LI
   LO
   TS
CP0967413
N2-isopropyl-N4-phenyl-N6-m-tolyl-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C19H23ClN6
 1
1
IC50 = 490 nM
   TI
   LI
   LO
   TS
CP0949633
N2,N4-diphenyl-N6-((tetrahydro-2H-pyran-4-yl)methyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C21H25ClN6O
 1
1
IC50 = 520 nM
   TI
   LI
   LO
   TS
CP0966781
3-(4-(4-fluorophenylamino)-6-(phenylamino)-1,3,5-triazin-2-ylamino)propan-1-ol N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C18H20ClFN6O
 1
1
IC50 = 550 nM
   TI
   LI
   LO
   TS
CP0919527
3-(4,6-bis(phenylamino)-1,3,5-triazin-2-ylamino)propan-1-ol hydrochloride
   Show/Hide
C18H21ClN6O
 1
1
IC50 = 590 nM
   TI
   LI
   LO
   TS
CP0913582
N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C20H25ClN6O2
 1
1
IC50 = 630 nM
   TI
   LI
   LO
   TS
CP0966782
N2-(4-chlorophenyl)-N4-(4-fluorophenyl)-N6-((2-fluoropyridin-4-yl)methyl)-1,3,5-triazine-2,4,6-triamine N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C21H17Cl2F2N7
 1
1
IC50 = 650 nM
   TI
   LI
   LO
   TS
CP0893948
N-isopropyl-N',N''-bis(4-methoxyphenyl)-1,3,5-triazine-1,3,5-triamine hydrochloride
   Show/Hide
C20H25ClN6O2
 1
1
IC50 = 660 nM
   TI
   LI
   LO
   TS
CP0848598
(R)-2-(4-(4-fluorophenylamino)-6-(phenylamino)-1,3,5-triazin-2-ylamino)propan-1-ol N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C18H20ClFN6O
 1
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
CP0913583
N2-isopropyl-N4-phenyl-N6-p-tolyl-1,3,5-triazine-2,4,6-triamine N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C19H23ClN6
 1
1
IC50 = 720 nM
   TI
   LI
   LO
   TS
CP0888276
N2,N4-bis(4-fluorophenyl)-N6-pentyl-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C20H23ClF2N6
 1
1
IC50 = 970 nM
   TI
   LI
   LO
   TS
CP0893952
N2-(3-methoxypropyl)-N4,N6-diphenyl-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C19H23ClN6O
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0867137
N2-(3-(methylthio)propyl)-N4,N6-diphenyl-1,3,5-triazine-2,4,6-triamine N2-(3-methoxypropyl)-N4,N6-diphenyl-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C19H23ClN6S
 1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0864322
N-[(6-aminopyridin-2-yl)methyl]-N'-(4-fluorophenyl)-N''-phenyl-1,3,5-triazine-2,4,6-triamine dihydrochloride
   Show/Hide
C21H21Cl2FN8
 1
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
CP0943837
6-(4,6-bis(phenylamino)-1,3,5-triazin-2-ylamino)-2-methylheptan-2-ol N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C23H31ClN6O
 1
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
CP0875181
2-(4-(4-fluorophenylamino)-6-(phenylamino)-1,3,5-triazin-2-ylamino)ethanol N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C17H18ClFN6O
 1
1
IC50 = 1500 nM
   TI
   LI
   LO
   TS
CP0911128
6-(2,2-dimethylhydrazinyl)-N2-(4-fluorophenyl)-N4-phenyl-1,3,5-triazine-2,4-diamine N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C17H19ClFN7
 1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS
CP0901761
N2-(5-(diethylamino)pentan-2-yl)-N4-(4-fluorophenyl)-N6-phenyl-1,3,5-triazine-2,4,6-triamine dihydrochloride
   Show/Hide
C24H34Cl2FN7
 1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
CP0894739
N2-((2-aminopyridin-4-yl)methyl)-N4-(4-fluorophenyl)-N6-phenyl-1,3,5-triazine-2,4,6-triamine dihydrochloride
   Show/Hide
C21H21Cl2FN8
 1
1
IC50 = 3600 nM
   TI
   LI
   LO
   TS
CP0864205
6-(ethoxyamino)-N2-(4-fluorophenyl)-N4-phenyl-1,3,5-triazine-2,4-diamine N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C17H18ClFN6O
 1
1
IC50 = 4700 nM
   TI
   LI
   LO
   TS
CP0895948
4-(2-(4,6-bis(phenylamino)-1,3,5-triazin-2-ylamino)ethyl)pyridine 1-oxide dihydrochloride
   Show/Hide
C22H23Cl2N7O
 1
1
IC50 = 4900 nM
   TI
   LI
   LO
   TS
CP0895949
N2-(4-fluorophenyl)-6-(methoxyamino)-N4-phenyl-1,3,5-triazine-2,4-diamine N2-isopropyl-N4,N6-bis(3-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine hydrochloride
   Show/Hide
C16H16ClFN6O
 1
1
IC50 = 9500 nM
   TI
   LI
   LO
   TS