Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
 Cell Line Info 
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT06044 , Extracellular calcium-sensing receptor
 Protein Info 
Gene Name CASR
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P48442
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011
 Cell Line Info 
 Protein ID: PT06044
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0856164
 Compound Info 
N-[(1S,2S)-2-((R)-1-naphthalen-1-yl-ethylamino)-cyclohexyl]-4-trifluoromethoxy-benzamide hydrochloride
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C26H28ClF3N2O2
  1
1
IC50 = 250 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0881777
 Compound Info 
3,4-dichloro-N-((1S,2S)-2-((R)-1-(naphthalen-1-yl)ethylamino)cyclohexyl)benzamide hydrochloride
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C25H27Cl3N2O
  1
1
IC50 = 330 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0172829
 Compound Info 
(R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile
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C24H25ClN2O2
  1
1
IC50 = 460 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0886344
 Compound Info 
N1-[4-(trifluoromethoxy)benzoyl]-N2-[1-(1-naphthyl)ethyl]-trans-1,2-diaminocyclohexane hydrochloride
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C26H28ClF3N2O2
  1
1
IC50 = 900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0856099
 Compound Info 
N-((1R,2R)-2-((R)-1-(naphthalen-1-yl)ethylamino)cyclohexyl)-4-(trifluoromethoxy)benzamide hydrochloride
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C26H28ClF3N2O2
  1
1
IC50 = 1700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0886345
 Compound Info 
N-[(1S,2S)-2-((R)-1-naphthalen-1-yl-ethylamino)-cyclohexyl]-4-trifluoromethoxy-benzenesulfonamide hydrochloride
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C25H28ClF3N2O3S
  1
1
IC50 = 2600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0856101
 Compound Info 
N1-[4-(trifluoromethoxy)benzenesulfonyl)-N2-[1-(1-naphthyl)ethyl]-trans-1,2-diaminocyclohexane hydrochloride
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C25H28ClF3N2O3S
  1
1
IC50 = 5400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0853351
 Compound Info 
4-methoxy-N-((1R,2R)-2-(1-(naphthalen-1-yl)ethylamino)cyclohexyl)benzenesulfonamide hydrochloride
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C25H31ClN2O3S
  1
1
IC50 = 8000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS