| Compound ID |
Compound Name |
Compound Formula |
|
CP0525469
|
6-(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)-3-[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]-1H-pyridin-2-one
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|
C30H33ClN4O5S2
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
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CP0539969
|
2-chloro-4-ethoxy-N-[[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrrolidin-1-ylbenzamide
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|
C27H33ClN6O3S
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
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CP0520969
|
2-chloro-4-ethoxy-N-[[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrazol-1-ylbenzamide
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|
C26H28ClN7O3S
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
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CP0549342
|
3-(1,3-benzothiazol-2-yl)-6-(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)-1H-pyridin-2-one
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|
C24H22ClN3O3S
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
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CP0516429
|
6-(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)-3-[5-(2-hydroxyacetyl)-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl]-1H-pyridin-2-one
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|
C25H27ClN4O5S
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
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CP0540754
|
2-chloro-4-ethoxy-N-[[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrrol-1-ylbenzamide
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|
C27H29ClN6O3S
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
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CP0414343
|
2-chloro-4-ethoxy-N-[[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrazol-1-ylbenzamide
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|
C26H27ClN6O5S2
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
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CP0539968
|
2-chloro-4-ethoxy-5-[(2R)-2-methylmorpholin-4-yl]-N-[[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]carbamoyl]benzamide
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|
C28H35ClN6O4S
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
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CP0368589
|
2-chloro-5-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-ethoxy-N-[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]benzamide
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|
C30H40ClN5O5S2
|
1
|
| 1 |
EC50 = 54 nM
|
|
|
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CP0323172
|
2-chloro-4-ethoxy-N-[[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-morpholin-4-ylbenzamide
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|
C27H33ClN6O4S
|
1
|
| 1 |
EC50 = 74 nM
|
|
|
|
CP0487588
|
6-(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)-3-[5-(2-methoxyacetyl)-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl]-1H-pyridin-2-one
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|
C26H29ClN4O5S
|
1
|
| 1 |
EC50 = 75 nM
|
|
|
|
CP0568792
|
2-chloro-4-ethoxy-5-morpholin-4-yl-N-[(5-phenyl-1,3-thiazol-2-yl)carbamoyl]benzamide
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|
C23H23ClN4O4S
|
1
|
| 1 |
EC50 = 103 nM
|
|
|
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CP0487589
|
2-chloro-4-ethoxy-N-[6-(1-methylpiperidin-4-yl)oxy-1,3-benzothiazol-2-yl]-5-morpholin-4-ylbenzamide
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|
C26H31ClN4O4S
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
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CP0446365
|
2-chloro-4-ethoxy-5-morpholin-4-yl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-ylcarbamoyl)benzamide
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|
C21H25ClN4O4S
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0571234
|
2-chloro-4-ethoxy-5-[(2R)-2-methylmorpholin-4-yl]-N-[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]benzamide
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|
C29H38ClN5O5S2
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0566130
|
2-chloro-4-ethoxy-N-[[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]carbamoyl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C27H32ClN5O6S2
|
1
|
| 1 |
EC50 = 166 nM
|
|
|
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CP0137373
|
2-(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)-5-[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]-1H-pyrimidin-6-one
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|
C29H32ClN5O5S2
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
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CP0402361
|
N-(1-benzothiophen-2-ylcarbamoyl)-2-chloro-4-ethoxy-5-morpholin-4-ylbenzamide
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|
C22H22ClN3O4S
|
1
|
| 1 |
EC50 = 260 nM
|
|
|
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CP0339575
|
2-chloro-5-[(2S,6S)-2,6-dimethylmorpholin-4-yl]-4-ethoxy-N-[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]benzamide
Show/Hide
|
C30H40ClN5O5S2
|
1
|
| 1 |
EC50 = 270 nM
|
|
|
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CP0570208
|
N-(1,3-benzothiazol-2-ylcarbamoyl)-2-chloro-4-ethoxy-5-morpholin-4-ylbenzamide
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|
C21H21ClN4O4S
|
1
|
| 1 |
EC50 = 299 nM
|
|
|
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CP0570206
|
2-chloro-4-ethoxy-N-[[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-(1H-pyrazol-5-yl)benzamide
Show/Hide
|
C26H28ClN7O3S
|
1
|
| 1 |
EC50 = 360 nM
|
|
|
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CP0367161
|
2-chloro-4-ethoxy-N-[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C26H32ClN5O3S
|
1
|
| 1 |
EC50 = 410 nM
|
|
|
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CP0121389
|
5-(1,3-benzothiazol-2-yl)-2-(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)-1H-pyrimidin-6-one
Show/Hide
|
C23H21ClN4O3S
|
1
|
| 1 |
EC50 = 490 nM
|
|
|
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CP0570207
|
2-chloro-4-ethoxy-N-[[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]carbamoyl]benzamide
Show/Hide
|
C23H26ClN5O3S
|
1
|
| 1 |
EC50 = 560 nM
|
|
|
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CP0367162
|
2-chloro-4-ethoxy-N-[6-[3-(4-methylpiperazin-1-yl)propylsulfonyl]-1,3-benzothiazol-2-yl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C28H36ClN5O5S2
|
1
|
| 1 |
EC50 = 600 nM
|
|
|
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CP0386983
|
N-[(5-acetyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]-2-chloro-4-ethoxy-5-morpholin-4-ylbenzamide
Show/Hide
|
C22H26ClN5O5S
|
1
|
| 1 |
EC50 = 719 nM
|
|
|
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CP0517571
|
2-chloro-4-ethoxy-N-[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C26H31ClN4O5S2
|
1
|
| 1 |
EC50 = 740 nM
|
|
|
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CP0525773
|
4-ethoxy-N-[[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]carbamoyl]-3-morpholin-4-ylbenzamide
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|
C27H34N6O4S
|
1
|
| 1 |
EC50 = 740 nM
|
|
|
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CP0572192
|
2-chloro-4-ethoxy-N-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C18H21ClN4O4S
|
1
|
| 1 |
EC50 = 769 nM
|
|
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CP0516454
|
2-chloro-4-ethoxy-N-[[5-(2-hydroxyacetyl)-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-2-yl]carbamoyl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C22H26ClN5O6S
|
1
|
| 1 |
EC50 = 895 nM
|
|
|
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CP0558996
|
4-ethoxy-N-[[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-morpholin-4-yl-2-(trifluoromethyl)benzamide
Show/Hide
|
C28H33F3N6O4S
|
1
|
| 1 |
EC50 = 1400 nM
|
|
|
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CP0368590
|
N-(1,3-benzothiazol-2-yl)-2-chloro-4-ethoxy-5-morpholin-4-ylbenzamide
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|
C20H20ClN3O3S
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
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CP0516491
|
2-chloro-4-fluoro-N-[[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrazol-1-ylbenzamide
Show/Hide
|
C24H22ClFN6O4S2
|
1
|
| 1 |
EC50 = 3600 nM
|
|
|
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CP0517572
|
2-chloro-4-methyl-N-[[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrazol-1-ylbenzamide
Show/Hide
|
C25H25ClN6O4S2
|
1
|
| 1 |
EC50 = 6100 nM
|
|
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CP0388289
|
2-chloro-N-[[6-(1-methylpiperidin-4-yl)sulfonyl-1,3-benzothiazol-2-yl]carbamoyl]-5-pyrazol-1-ylbenzamide
Show/Hide
|
C24H23ClN6O4S2
|
1
|
| 1 |
EC50 = 7000 nM
|
|
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CP0525468
|
2-chloro-4-ethoxy-N-methyl-N-[[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C28H35ClN6O4S
|
1
|
| 1 |
EC50 > 16000 nM
|
|
|
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CP0414309
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1-[(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)methyl]-3-[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]urea
Show/Hide
|
C27H35ClN6O3S
|
1
|
| 1 |
EC50 > 33000 nM
|
|
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CP0535089
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1-(2-chloro-4-ethoxy-5-morpholin-4-ylphenyl)-3-[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]urea
Show/Hide
|
C26H33ClN6O3S
|
1
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| 1 |
EC50 > 33000 nM
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CP0574209
|
4-ethoxy-2-methyl-N-[[6-[(4-methylpiperazin-1-yl)methyl]-1,3-benzothiazol-2-yl]carbamoyl]-5-morpholin-4-ylbenzamide
Show/Hide
|
C28H36N6O4S
|
1
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| 1 |
EC50 > 3700 nM
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