| Compound ID |
Compound Name |
Compound Formula |
|
CP0930024
|
3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(benzo[b]thiophen-2-ylmethyl)benzamide Hydrochloride
Show/Hide
|
C23H19ClF3N3O2S
|
3
|
| 1 |
IC50 = 34 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
| 3 |
IC50 < 300 nM
|
|
|
|
CP0775033
|
3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(2-sulfamoylethyl)benzamide Hydrochloride
Show/Hide
|
C16H18ClF3N4O4S
|
3
|
| 1 |
IC50 = 35 nM
|
|
|
| 2 |
IC50 = 62 nM
|
|
|
| 3 |
IC50 < 300 nM
|
|
|
|
CP0756410
|
3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-phenylbenzamide Hydrochloride
Show/Hide
|
C20H17ClF3N3O2
|
3
|
| 1 |
IC50 = 42 nM
|
|
|
| 2 |
IC50 = 62 nM
|
|
|
| 3 |
IC50 < 300 nM
|
|
|
|
CP0757384
|
N-(2-(1H-Tetrazol-1-yl)ethyl)-3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzamide Hydrochloride
Show/Hide
|
C17H17ClF3N7O2
|
3
|
| 1 |
IC50 = 43 nM
|
|
|
| 2 |
IC50 = 80 nM
|
|
|
| 3 |
IC50 < 300 nM
|
|
|
|
CP0901481
|
3-((4-(Aminomethyl)pyridin-2-yl)oxy)-N-(4-fluorophenyl)-benzamide Hydrochloride
Show/Hide
|
C19H17ClFN3O2
|
2
|
| 1 |
IC50 = 50 nM
|
|
|
| 2 |
IC50 = 130 nM
|
|
|
|
CP0912863
|
3-((4-(Aminomethyl)pyridin-2-yl)oxy)-N-(4-methoxyphenyl)-benzamide Hydrochloride
Show/Hide
|
C20H20ClN3O3
|
2
|
| 1 |
IC50 = 53 nM
|
|
|
| 2 |
IC50 = 160 nM
|
|
|
|
CP0902471
|
3-((4-(Aminomethyl)pyridin-2-yl)oxy)-N-phenylbenzamide Hydrochloride
Show/Hide
|
C19H18ClN3O2
|
2
|
| 1 |
IC50 = 56 nM
|
|
|
| 2 |
IC50 = 130 nM
|
|
|
|
CP0430322
|
[3-[4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxyphenyl]-[(3R)-3-aminopyrrolidin-1-yl]methanone;dihydrochloride
Show/Hide
|
C18H21Cl2F3N4O2
|
3
|
| 1 |
IC50 = 58 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
| 3 |
IC50 < 300 nM
|
|
|
|
CP0930294
|
3-((4-(Aminomethyl)pyridin-2-yl)oxy)-N-benzylbenzamide Hydrochloride
Show/Hide
|
C20H20ClN3O2
|
2
|
| 1 |
IC50 = 62 nM
|
|
|
| 2 |
IC50 = 110 nM
|
|
|
|
CP0326412
|
CHEBI:27413
Show/Hide
|
C3H6N2
|
5
|
| 1 |
IC50 = 66 nM
|
|
|
| 2 |
IC50 = 83 nM
|
|
|
| 3 |
IC50 = 240 nM
|
|
|
| 4 |
IC50 = 243 nM
|
|
|
| 5 |
IC50 = 396 nM
|
|
|
|
CP0520208
|
[2-(3-phenoxyphenoxy)-6-(trifluoromethyl)pyridin-4-yl]methanamine
Show/Hide
|
C19H15F3N2O2
|
2
|
| 1 |
IC50 = 67 nM
|
|
|
| 2 |
IC50 = 270 nM
|
|
|
|
CP0237362
|
[3-[4-(aminomethyl)pyridin-2-yl]oxyphenyl]-[(3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl]methanone;hydrochloride
Show/Hide
|
C17H19ClFN3O3
|
2
|
| 1 |
IC50 = 74 nM
|
|
|
| 2 |
IC50 = 110 nM
|
|
|
|
CP0261509
|
3-[4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-[(2R)-2,3-dihydroxypropyl]benzamide;hydrochloride
Show/Hide
|
C17H19ClF3N3O4
|
3
|
| 1 |
IC50 = 77 nM
|
|
|
| 2 |
IC50 = 88 nM
|
|
|
| 3 |
IC50 < 300 nM
|
|
|
|
CP0327496
|
[3-[4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxyphenyl]-[(3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl]methanone;hydrochloride
Show/Hide
|
C18H18ClF4N3O3
|
2
|
| 1 |
IC50 = 78 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0901482
|
3-((4-(Aminomethyl)pyridin-2-yl)oxy)-N-(benzo[b]thiophen-2-ylmethyl)benzamide Hydrochloride
Show/Hide
|
C22H20ClN3O2S
|
2
|
| 1 |
IC50 = 79 nM
|
|
|
| 2 |
IC50 = 110 nM
|
|
|
|
CP0901484
|
4-(3-((4-(Aminomethyl)pyridin-2-yl)oxy)benzamido)benzoic Acid Hydrochloride
Show/Hide
|
C20H18ClN3O4
|
2
|
| 1 |
IC50 = 81 nM
|
|
|
| 2 |
IC50 = 300 nM
|
|
|
|
CP0224605
|
[3-[4-(aminomethyl)pyridin-2-yl]oxyphenyl]-[(3S,4S)-3-fluoro-4-hydroxypyrrolidin-1-yl]methanone;hydrochloride
Show/Hide
|
C17H19ClFN3O3
|
2
|
| 1 |
IC50 = 82 nM
|
|
|
| 2 |
IC50 = 120 nM
|
|
|
|
CP0903503
|
3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-methoxybenzamide Hydrochloride
Show/Hide
|
C15H15ClF3N3O3
|
3
|
| 1 |
IC50 = 96 nM
|
|
|
| 2 |
IC50 = 140 nM
|
|
|
| 3 |
IC50 < 300 nM
|
|
|
|
CP0853222
|
N-((1H-pyrrolo[2,3-b]pyridin-2-yl)methyl)-3-(((6-(aminomethyl)pyrimidin-4-yl)oxy)methyl)benzamide hydrochloride
Show/Hide
|
C21H21ClN6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0853223
|
(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)phenyl)(4-hydroxy-4-(trifluoromethyl)piperidin-1-yl)methanone hydrochloride
Show/Hide
|
C18H20ClF3N4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0853224
|
3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-(benzo[d]oxazol-2-ylmethyl)benzamide hydrochloride
Show/Hide
|
C20H18ClN5O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0853225
|
(6-((1H-Indazol-4-yl)oxy)pyrimidin-4-yl)methanamine hydrochloride
Show/Hide
|
C12H12ClN5O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0864161
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)(methyl)amino)methyl)-N-phenylbenzamide hydrochloride
Show/Hide
|
C20H22ClN5O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0869553
|
5-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-1-((6-methoxypyridin-3-yl)methyl)-3,4-dihydroquinolin-2(1H)-one trifluoroacetate
Show/Hide
|
C23H22F3N5O5
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0869563
|
(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)phenyl)(4-phenylpiperazin-1-yl)methanone methanesulfonate
Show/Hide
|
C23H27N5O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0869564
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N,N-dimethylbenzamide Trifluoroacetate
Show/Hide
|
C17H19F3N4O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0869565
|
3-((4-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-1H-indol-1-yl)methyl)benzoic acid Trifluoroacetate
Show/Hide
|
C23H19F3N4O5
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0871725
|
3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-(2-hydroxyethyl)benzamide hydrochloride
Show/Hide
|
C14H17ClN4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0876547
|
(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)phenyl)(4,4-dimethylpiperidin-1-yl)methanone hydrochloride
Show/Hide
|
C19H25ClN4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0876548
|
N-((1H-Indol-2-yl)methyl)-3-((6-(aminomethyl)pyrimidin-4-yl)oxy)benzamide hydrochloride
Show/Hide
|
C21H20ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0878860
|
(3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)phenyl)(4-hydroxy-4-(trifluoromethyl)piperidin-1-yl)methanone hydrochloride
Show/Hide
|
C19H22ClF3N4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0880223
|
(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)phenyl)(2,3-dihydro-1H-pyrrolo[2,3-c]pyridin-1-yl)methanone hydrochloride
Show/Hide
|
C19H18ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0882227
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)amino)methyl)-N-(3-(trifluoromethyl)phenyl)benzamide hydrochloride
Show/Hide
|
C20H19ClF3N5O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0882228
|
N-((1H-Pyrrolo[2,3-b]pyridin-2-yl)methyl)-3-((6-(aminomethyl)pyrimidin-4-yl)oxy)benzamide hydrochloride
Show/Hide
|
C20H19ClN6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0882229
|
3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-((3-chlorobenzo[b]thiophen-2-yl)methyl)benzamide hydrochloride
Show/Hide
|
C21H18Cl2N4O2S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0882230
|
3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-benzylbenzamide hydrochloride
Show/Hide
|
C19H19ClN4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0894328
|
(3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)phenyl)(4-phenylpiperazin-1-yl)methanone hydrochloride
Show/Hide
|
C23H26ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0894331
|
(R)-Methyl 3-(3-((6-(aminomethyl)pyrimidin-4-yl)oxy)benzamido)pent-4-ynoate hydrochloride
Show/Hide
|
C18H19ClN4O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0894333
|
3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-(pyridin-3-ylmethyl)benzamide hydrochloride
Show/Hide
|
C18H18ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0894334
|
5-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-1-(2-(methyl sulfonyl)ethyl)-3,4-dihydroquinolin-2(1H)-one hydrochloride
Show/Hide
|
C17H21ClN4O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0903077
|
(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)phenyl)(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)methanone hydrochloride
Show/Hide
|
C19H18ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0903078
|
3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-(2-sulfamoylethyl)benzamide hydrochloride
Show/Hide
|
C14H18ClN5O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0903079
|
(6-(3-Phenoxyphenoxy)pyrimidin-4-yl)methanamine hydrochloride
Show/Hide
|
C17H16ClN3O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0904052
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-(benzo[d]oxazol-2-ylmethyl)benzamide hydrochloride
Show/Hide
|
C21H20ClN5O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0904053
|
3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-((5-fluoro-1H-indol-2-yl)methyl)benzamide hydrochloride
Show/Hide
|
C21H19ClFN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0904054
|
(6-((1-(Oxetan-3-yl)-1H-indol-4-yl)oxy)pyrimidin-4-yl)methanamine
Show/Hide
|
C16H16N4O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0904055
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-benzylbenzamide hydrochloride
Show/Hide
|
C20H21ClN4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0904056
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-(2-hydroxy-2-methylpropyl)benzamide Trifluoroacetate
Show/Hide
|
C19H23F3N4O5
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0904057
|
(6-((1-(2-(Methylsulfonyl)ethyl)-1H-indol-4-yl)oxy)pyrimidin-4-yl)methanamine
Show/Hide
|
C16H18N4O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0904058
|
4-(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)benzamido)butanoic acid hydrochloride
Show/Hide
|
C16H19ClN4O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0904136
|
1-(6-(Aminomethyl)pyrimidin-4-yl)-5-(benzyloxy)-3,4-dihydroquinolin-2(1H)-one hydrochloride
Show/Hide
|
C21H21ClN4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0904137
|
(3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)phenyl)(5H-pyrrolo[2,3-b:5,4-c']dipyridin-7(6H,8H,9H)-yl)methanone hydrochloride
Show/Hide
|
C23H23ClN6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0904138
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-((5-fluoro-1H-indol-2-yl)methyl)benzamide hydrochloride
Show/Hide
|
C22H21ClFN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0942151
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)amino)methyl)-N-(benzo[b]thiophen-2-ylmethyl)benzamide hydrochloride
Show/Hide
|
C22H22ClN5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0942152
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-(pyridin-3-ylmethyl)benzamide hydrochloride
Show/Hide
|
C19H20ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0942153
|
(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)phenyl)(5H-pyrrolo[2,3-b:5,4-c']dipyridin-7(6H,8H,9H)-yl)methanone hydrochloride
Show/Hide
|
C22H21ClN6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0942154
|
(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)phenyl)(3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)methanone hydrochloride
Show/Hide
|
C19H21ClN6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0942155
|
3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-(quinolin-2-ylmethyl)benzamide hydrochloride
Show/Hide
|
C22H20ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0942156
|
(R)-3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-(2-hydroxy-1-phenylethyl)benzamide hydrochloride
Show/Hide
|
C20H21ClN4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0942157
|
(6-((1-(1-Methyl-1H-pyrazol-4-yl)-1H-indol-4-yl)oxy)pyrimidin-4-yl)methanamine
Show/Hide
|
C17H16N6O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0943689
|
1-(6-(Aminomethyl)pyrimidin-4-yl)-N-phenylpiperidine-4-carboxamide hydrochloride
Show/Hide
|
C17H22ClN5O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0943690
|
(S)-Methyl 3-(3-((6-(aminomethyl)pyrimidin-4-yl)oxy)benzamido)pent-4-ynoate hydrochloride
Show/Hide
|
C18H19ClN4O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0943691
|
2-(4-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-1H-indol-1-yl)ethan-1-ol
Show/Hide
|
C15H16N4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0943694
|
3-(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)benzamido)propanoic acid hydrochloride
Show/Hide
|
C15H17ClN4O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0943696
|
3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-phenylbenzamide hydrochloride
Show/Hide
|
C18H17ClN4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0943698
|
(6-(4-Fluorophenoxy)pyrimidin-4-yl)methanamine trifluoroacetate
Show/Hide
|
C13H11F4N3O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944238
|
4-(6-(Aminomethyl)pyrimidin-4-yl)-N-phenylpiperazine-1-carboxamide acetate
Show/Hide
|
C18H24N6O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0944239
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-(3-(trifluoromethyl)phenyl)benzamide hydrochloride
Show/Hide
|
C20H18ClF3N4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944240
|
N-(2-(1H-Pyrazol-1-yl)ethyl)-3-(((6-(aminomethyl)pyrimidin-4-yl)oxy)methyl)benzamide Trifluoroacetate
Show/Hide
|
C20H21F3N6O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944241
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-(2-(2-oxooxazolidin-3-yl)ethyl)benzamide Trifluoroacetate
Show/Hide
|
C20H22F3N5O6
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944242
|
(5-(6-(Aminomethyl)pyrimidin-4-yl)oxy)-1-(2-hydroxyethyl)-3,4-dihydroquinolin-2(1H)-one hydrochloride
Show/Hide
|
C16H19ClN4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944243
|
2-(5-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-2-oxo-3,4-dihydroquinolin-1 (2H)-yl)acetic acid hydrochloride
Show/Hide
|
C16H17ClN4O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0944244
|
3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-(2-(methylsulfonyl)ethyl)benzamide hydrochloride
Show/Hide
|
C15H19ClN4O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0946419
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-((5-fluorobenzo[b]thiophen-2-yl)methyl)benzamide hydrochloride
Show/Hide
|
C22H20ClFN4O2S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0946420
|
Methyl 2-(4-((6-(aminomethyl)pyrimidin-4-yl)oxy)-1H-indol-1-yl)acetate acetate
Show/Hide
|
C18H20N4O5
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951288
|
(3-(((6-(Aminomethyl)pyrimidin-4-yl)amino)methyl)phenyl)(4-phenylpiperazin-1-yl)methanone hydrochloride
Show/Hide
|
C23H27ClN6O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951289
|
(1-(6-(Aminomethyl)pyrimidin-4-yl)-1H-indol-4-yl)methanol Trifluoroacetate
Show/Hide
|
C16H15F3N4O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0951290
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-(benzo[b]thiophen-2-ylmethyl)benzamide hydrochloride
Show/Hide
|
C22H21ClN4O2S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951291
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-((2-chloropyridin-4-yl)methyl)benzamide hydrochloride
Show/Hide
|
C19H19Cl2N5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951292
|
(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)phenyl)(4-(3,5-dichloropyridin-2-yl)piperazin-1-yl)methanone hydrochloride
Show/Hide
|
C21H21Cl3N6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951293
|
3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-((1-methyl-1H-indol-2-yl)methyl)benzamide hydrochloride
Show/Hide
|
C22H22ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951294
|
(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)phenyl)(6-chloroindolin-1-yl)methanone hydrochloride
Show/Hide
|
C20H18Cl2N4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951295
|
(6-((1-Benzyl-1H-indol-4-yl)oxy)pyrimidin-4-yl)methanamine hydrochloride
Show/Hide
|
C20H19ClN4O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951296
|
(6-((1-Ethyl-1H-indol-4-yl)oxy)pyrimidin-4-yl)methanamine acetate
Show/Hide
|
C17H20N4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951297
|
(6-((1H-Indol-4-yl)oxy)pyrimidin-4-yl)methanamine hydrochloride
Show/Hide
|
C13H13ClN4O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951298
|
3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-(benzo[b]thiophen-2-ylmethyl)benzamide hydrochloride
Show/Hide
|
C21H19ClN4O2S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951442
|
(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)phenyl)(5,6-dihydro-1,7-naphthyridin-7(8H)-yl)methanone hydrochloride
Show/Hide
|
C20H20ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951444
|
N-(2-(1H-Tetrazol-1-yl)ethyl)-3-(((6-(aminomethyl)pyrimidin-4-yl)oxy)methyl)benzamide hydrochloride
Show/Hide
|
C16H19ClN8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0951450
|
4-(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)benzamido)benzoic acid hydrochloride
Show/Hide
|
C19H17ClN4O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0953099
|
3-((6-(Aminomethyl)pyrimidin-4-yl)amino)-N-phenylbenzamide hydrochloride
Show/Hide
|
C18H18ClN5O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0953100
|
Rac-3-(((6-(aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-((3-methyl-2-oxooxazolidin-5-yl)methyl)benzamide Trifluoroacetate
Show/Hide
|
C20H22F3N5O6
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0953102
|
Methyl 3-((4-((6-(aminomethyl)pyrimidin-4-yl)oxy)-1H-indol-1-yl)methyl)benzoate
Show/Hide
|
C22H20N4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0953103
|
2-(4-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-1H-indol-1-yl)-1-(piperidin-1-yl)ethan-1-one
Show/Hide
|
C20H23N5O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0953104
|
(6-((1H-Indol-5-yl)oxy)pyrimidin-4-yl)methanamine trifluoroacetate
Show/Hide
|
C15H13F3N4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0953106
|
(S)-(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)phenyl)(3-hydroxypyrrolidin-1-yl)methanone
Show/Hide
|
C16H19ClN4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0959240
|
(R)-3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-(2-hydroxy-1-phenylethyl)benzamide hydrochloride
Show/Hide
|
C21H23ClN4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0960317
|
(3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)phenyl)(5,6-dihydro-1,7-naphthyridin-7(8H)-yl)methanone Trifluoroacetate
Show/Hide
|
C23H22F3N5O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0960318
|
(3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)phenyl)(4-(pyridin-2-yl)piperazin-1-yl)methanone hydrochloride
Show/Hide
|
C21H23ClN6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0960319
|
4-(3-(((6-(Aminomethyl)pyrimidin-4-yl)amino)methyl)benzamido)benzoic acid hydrochloride
Show/Hide
|
C20H20ClN5O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0960321
|
(6-((1-((6-Methoxypyridin-3-yl)methyl)-3-methyl-1H-indol-4-yl)oxy)pyrimidin-4-yl)methanamine Trifluoroacetate
Show/Hide
|
C23H22F3N5O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0960322
|
(6-((1-((6-Methoxypyridin-3-yl)methyl)-1H-indol-5-yl)oxy)pyrimidin-4-yl)methanamine acetate
Show/Hide
|
C22H23N5O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0960323
|
4-((3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)benzamido)methyl)benzoic acid hydrochloride
Show/Hide
|
C20H19ClN4O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0961394
|
5-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C15H18N4O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0961395
|
Rac-3-(1-((6-(aminomethyl)pyrimidin-4-yl)oxy)ethyl)-N-phenylbenzamide hydrochloride
Show/Hide
|
C20H21ClN4O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0961396
|
(3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)phenyl)(2,3-dihydro-1H-pyrrolo[2,3-c]pyridin-1-yl)methanone hydrochloride
Show/Hide
|
C20H20ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0961397
|
(3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)phenyl)(3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)methanone hydrochloride
Show/Hide
|
C20H23ClN6O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0961398
|
N-((1H-indol-2-yl)methyl)-3-(((6-(aminomethyl)pyrimidin-4-yl)oxy)methyl)benzamide hydrochloride
Show/Hide
|
C22H22ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0961399
|
3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-((4'-fluoro-[1,1'-biphenyl]-4-yl)methyl)benzamide hydrochloride
Show/Hide
|
C25H22ClFN4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0961400
|
(1-(6-(Aminomethyl)pyrimidin-4-yl)-1H-indazol-4-yl)methanol hydrochloride
Show/Hide
|
C13H14ClN5O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0961767
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)amino)methyl)-N-phenylbenzamide hydrochloride
Show/Hide
|
C19H20ClN5O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0961768
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-(2-(methylsulfonyl)ethyl)benzamide Trifluoroacetate
Show/Hide
|
C18H21F3N4O6S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0968393
|
(R)-1-(6-(Aminomethyl)pyrimidin-4-yl)-N-phenylpyrrolidine-3-carboxamide hydrochloride
Show/Hide
|
C16H20ClN5O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0968394
|
(3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)phenyl)(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)methanone hydrochloride
Show/Hide
|
C20H20ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0968402
|
2-(4-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-1H-indol-1-yl)acetic acid Trifluoroacetate
Show/Hide
|
C17H15F3N4O5
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0968935
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)amino)methyl)-N-((3-chlorobenzo[b]thiophen-2-yl)methyl)benzamide hydrochloride
Show/Hide
|
C22H21Cl2N5OS
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0968936
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-((1-methyl-1H-indol-2-yl)methyl)benzamide hydrochloride
Show/Hide
|
C23H24ClN5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0968945
|
3-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-N-((2-chloropyridin-4-yl)methyl)benzamide hydrochloride
Show/Hide
|
C18H17Cl2N5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0969407
|
1-(4-(6-(Aminomethyl)pyrimidin-4-yl)piperazin-1-yl)-2-phenylethanone acetate
Show/Hide
|
C19H25N5O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0969409
|
(6-((1H-Indol-6-yl)oxy)pyrimidin-4-yl)methanamine
Show/Hide
|
C13H12N4O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0969413
|
(6-((1-((6-Methoxypyridin-3-yl)methyl)-2-methyl-1H-indol-4-yl)oxy)pyrimidin-4-yl)methanamine Trifluoroacetate
Show/Hide
|
C23H22F3N5O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0969736
|
Rac-trans-(3-((6-(aminomethyl)pyrimidin-4-yl)oxy)phenyl)(3-fluoro-4-hydroxypyrrolidin-1-yl)methanone hydrochloride
Show/Hide
|
C16H18ClFN4O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0969742
|
3-(((6-(Aminomethyl)pyrimidin-4-yl)oxy)methyl)-N-phenylbenzamide hydrochloride
Show/Hide
|
C19H19ClN4O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0969743
|
Rac-(3-(((6-(aminomethyl)pyrimidin-4-yl)oxy)methyl)phenyl)(3-hydroxy-3-(trifluoromethyl)piperidin-1-yl)methanone Trifluoroacetate
Show/Hide
|
C21H22F6N4O5
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0969745
|
2-(4-((6-(Aminomethyl)pyrimidin-4-yl)oxy)-1H-indol-1-yl)-N-methyl-N-phenylacetamide
Show/Hide
|
C22H21N5O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0330327
|
[3-[4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxyphenyl]-[(3R)-3-hydroxypyrrolidin-1-yl]methanone;hydrochloride
Show/Hide
|
C18H19ClF3N3O3
|
3
|
| 1 |
IC50 = 110 nM
|
|
|
| 2 |
IC50 = 150 nM
|
|
|
| 3 |
IC50 < 300 nM
|
|
|
|
CP0468819
|
[3-[4-(aminomethyl)pyridin-2-yl]oxyphenyl]-(3,4-dihydro-1H-isoquinolin-2-yl)methanone
Show/Hide
|
C22H21N3O2
|
2
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
IC50 = 370 nM
|
|
|
|
CP0107701
|
(2-chloropyridin-4-yl)methanamine
Show/Hide
|
C6H7ClN2
|
3
|
| 1 |
IC50 = 126 nM
|
|
|
| 2 |
IC50 = 190 nM
|
|
|
| 3 |
IC50 = 1450 nM
|
|
|
|
CP0468821
|
(3S)-3-[4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-phenylpiperidine-1-carboxamide
Show/Hide
|
C19H21F3N4O2
|
2
|
| 1 |
IC50 = 130 nM
|
|
|
| 2 |
IC50 = 160 nM
|
|
|
|
CP0912862
|
3-((4-(Aminomethyl)pyridin-2-yl)oxy)-N-(2-methoxyethyl)-benzamide Hydrochloride
Show/Hide
|
C16H20ClN3O3
|
2
|
| 1 |
IC50 = 160 nM
|
|
|
| 2 |
IC50 = 290 nM
|
|
|
|
CP0901483
|
3-((4-(Aminomethyl)pyridin-2-yl)oxy)-N-(3-carbamimidoylbenzyl)benzamide Dihydrochloride
Show/Hide
|
C21H23Cl2N5O2
|
2
|
| 1 |
IC50 = 180 nM
|
|
|
| 2 |
IC50 = 650 nM
|
|
|
|
CP0455797
|
(2-imidazol-1-ylpyridin-4-yl)methanamine
Show/Hide
|
C9H10N4
|
1
|
| 1 |
IC50 = 203 nM
|
|
|
|
CP0930479
|
4-((4-(Aminomethyl)pyridin-2-yl)oxy)-N-phenylbenzamide Hydrochloride
Show/Hide
|
C19H18ClN3O2
|
2
|
| 1 |
IC50 = 270 nM
|
|
|
| 2 |
IC50 = 750 nM
|
|
|
|
CP0446683
|
BDBM509202
Show/Hide
|
C20H20F3N3O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0874555
|
3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-hydroxybenzamide hydrochloride
Show/Hide
|
C14H13ClF3N3O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0874556
|
3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzoic acid hydrochloride
Show/Hide
|
C14H12ClF3N2O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0874567
|
5-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-1-(2-hydroxyethyl)-3,4-dihydroquinolin-2(1H)-one hydrochloride
Show/Hide
|
C18H19ClF3N3O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0883981
|
Rac-trans-(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-5-methoxyphenyl)(3-fluoro-4-hydroxypyrrolidin-1-yl)methanone hydrochloride
Show/Hide
|
C19H20ClF4N3O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0887835
|
1-(2-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-6-azaspiro[3.4]octan-6-yl)ethanone hydrochloride
Show/Hide
|
C16H21ClF3N3O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0901647
|
3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)methyl)-6-methyl-1-(pyrimidin-4-ylmethyl)pyrimidine-2,4(1H,3H)-dione hydrochloride
Show/Hide
|
C18H18ClF3N6O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0903887
|
2-(4-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-1H-indol-1-yl)-1-(piperidin-1-yl)ethanone
Show/Hide
|
C22H23F3N4O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0903894
|
(R)-3-(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzamido)pent-4-ynoic acid hydrochloride
Show/Hide
|
C19H17ClF3N3O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0903895
|
Rac-trans-(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-4-hydroxyphenyl)(3-fluoro-4-hydroxypyrrolidin-1-yl)methanone hydrochloride
Show/Hide
|
C18H18ClF4N3O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0905685
|
(S)-(3-(((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)amino)methyl)phenyl)(3-hydroxypyrrolidin-1-yl)methanone hydrochloride
Show/Hide
|
C19H22ClF3N4O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0909950
|
(S)-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)piperidin-1-yl)(5-methyl-1,3,4-oxadiazol-2-yl)methanone trifluoroacetate
Show/Hide
|
C18H19F6N5O5
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0909952
|
(S)-3-(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzamido)pent-4-ynoic acid
Show/Hide
|
C19H16F3N3O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0954540
|
4-(4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yloxy)-N-phenylpiperidine-1-carboxamide trifluoroacetate
Show/Hide
|
C21H22F6N4O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0956838
|
(R)-3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-phenylpiperidine-1-carboxamide trifluoroacetate
Show/Hide
|
C21H22F6N4O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0960247
|
2-(4-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-1H-indol-1-yl)-1-(piperazin-1-yl)ethan-1-one dihydrochloride
Show/Hide
|
C21H24Cl2F3N5O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0968624
|
(R)-1-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzoyl)pyrrolidine-2-carboxylic acid hydrochloride
Show/Hide
|
C19H19ClF3N3O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0970154
|
(S)-3-(((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)methyl)-N-phenylpiperidine-1-carboxamide trifluoroacetate
Show/Hide
|
C22H24F6N4O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0853183
|
2-(Aminomethyl)-4-oxo-N-(2-sulfamoylethyl)-4H-chromene-6-carboxamide hydrochloride
Show/Hide
|
C13H16ClN3O5S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0853184
|
(R)-2-(Aminomethyl)-6-(3-aminopyrrolidine-1-carbonyl)-4H-chromen-4-one dihydrochloride
Show/Hide
|
C15H19Cl2N3O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0853185
|
Methyl (R)-1-(2-(aminomethyl)-4-oxo-4H-chromene-6-carbonyl)pyrrolidine-3-carboxylate hydrochloride
Show/Hide
|
C17H19ClN2O5
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0874605
|
N-(2-(1H-1,2,4-Triazol-1-yl)ethyl)-2-(aminomethyl)-4-oxo-4H-chromene-6-carboxamide hydrochloride
Show/Hide
|
C15H16ClN5O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0874606
|
Rac-trans-2-(aminomethyl)-6-(3-fluoro-4-hydroxypyrrolidine-1-carbonyl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C15H16ClFN2O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0874607
|
2-(Aminomethyl)-N-(2-(methylsulfonyl)ethyl)-4-oxo-4H-chromene-6-carboxamide hydrochloride
Show/Hide
|
C14H17ClN2O5S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0874608
|
2-((2-(Aminomethyl)-4-oxo-4H-chromen-7-yl)oxy)-N,N-dimethylacetamide hydrochloride
Show/Hide
|
C14H17ClN2O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0949899
|
2-((2-(Aminomethyl)-4-oxo-4H-chromen-6-yl)oxy)-N,N-dimethylacetamide hydrochloride
Show/Hide
|
C14H17ClN2O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0954993
|
2-((2-(Aminomethyl)-4-oxo-4H-chromen-8-yl)oxy)-N-phenylacetamide hydrochloride
Show/Hide
|
C18H17ClN2O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0954994
|
2-(Aminomethyl)-6-((3R,4R)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C15H16ClFN2O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0955477
|
2-(aminomethyl)-6-(piperidine-1-carbonyl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C16H19ClN2O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0955480
|
2-(Aminomethyl)-8-hydroxy-4H-chromen-4-one hydrochloride
Show/Hide
|
C10H10ClNO3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0955481
|
2-(Aminomethyl)-8-(prop-2-yn-1-yloxy)-4H-chromen-4-one hydrochloride
Show/Hide
|
C13H12ClNO3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0955932
|
2-(Aminomethyl)-7-hydroxy-4H-chromen-4-one hydrochloride
Show/Hide
|
C10H10ClNO3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0959210
|
(S)-2-(aminomethyl)-6-(3-hydroxypyrrolidin-1-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C14H17ClN2O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0959211
|
2-(Aminomethyl)-6-((3S,4S)-3-fluoro-4-hydroxypyrrolidine-1-carbonyl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C15H16ClFN2O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0960878
|
2-(2-(Aminomethyl)-4-oxo-4H-chromen-6-yloxy)acetic acid hydrochloride
Show/Hide
|
C12H12ClNO5
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0961402
|
2-(Aminomethyl)-6-(1-(2-hydroxyethyl)-1H-1,2,3-triazol-4-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C14H15ClN4O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0961403
|
2-(aminomethyl)-7-ethynyl-4H-chromen-4-one hydrochloride
Show/Hide
|
C12H10ClNO2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0961407
|
2-(Aminomethyl)-8-bromo-4H-chromen-4-one hydrochloride
Show/Hide
|
C10H9BrClNO2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0968324
|
2-(Aminomethyl)-N-(2-hydroxyethyl)-4-oxo-4H-chromene-6-carboxamide hydrochloride
Show/Hide
|
C13H15ClN2O4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0969648
|
2-(Aminomethyl)-8-(benzyloxy)-4H-chromen-4-one hydrochloride
Show/Hide
|
C17H16ClNO3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0969649
|
2-(Aminomethyl)-8-phenethoxy-4H-chromen-4-one hydrochloride
Show/Hide
|
C18H18ClNO3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0430010
|
1-benzothiophen-2-ylmethanamine
Show/Hide
|
C9H9NS
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0534975
|
2-(4-phenyl-1,3-thiazol-2-yl)ethanamine;hydrochloride
Show/Hide
|
C11H12N2S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0874433
|
(5-(2-Methoxypyridin-3-yl)-1H-indol-2-yl)methanamine
Show/Hide
|
C15H15N3O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0874434
|
(5-(6-Methoxypyridin-3-yl)-1H-indol-2-yl)methanamine
Show/Hide
|
C15H15N3O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0874435
|
(5-(1-Methyl-1H-pyrazol-4-yl)-1H-indol-2-yl)methanamine
Show/Hide
|
C13H14N4
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0903538
|
(5-(6-(Benzyloxy)pyridin-3-yl)-1H-indol-2-yl)methanamine
Show/Hide
|
C21H19N3O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0905732
|
(5-Methoxy-1H-indol-2-yl)methanamine
Show/Hide
|
C10H12N2O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0910034
|
2-(4-(Pyridin-4-yl)thiazol-2-yl)ethanamine
Show/Hide
|
C10H11N3S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0910037
|
(5-Chlorobenzo[d]thiazol-2-yl)methanamine
Show/Hide
|
C8H7ClN2S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0915927
|
2-indolylmethanamine
Show/Hide
|
C9H10N2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0941859
|
3-(Aminomethyl)isoquinolin-1(2H)-one
Show/Hide
|
C10H10N2O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0941861
|
(5-Methyl-1H-indol-2-yl)methanamine
Show/Hide
|
C10H12N2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0944955
|
2-(Benzo[d]oxazol-2-yl)ethanamine
Show/Hide
|
C9H10N2O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0944962
|
5-(2-(Aminomethyl)-1H-indol-5-yl)pyridin-3-ol
Show/Hide
|
C14H13N3O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0948215
|
(Pyridazin-4-yl)methanamine
Show/Hide
|
C5H7N3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0948216
|
3-((5-(Aminomethyl)pyrazolo[1,5-a]pyrimidin-7-yl)oxy)-N-phenylbenzamide
Show/Hide
|
C20H17N5O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0951459
|
3-((4-(Aminomethyl)pyrimidin-2-yl)oxy)-N-phenylbenzamide
Show/Hide
|
C18H16N4O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0951556
|
(Rac)-2-(benzo[d]thiazol-2-yl)propan-1-amine
Show/Hide
|
C10H12N2S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0955151
|
5-(Aminomethyl)pyrazolo[1,5-a]pyrimidin-7-ol
Show/Hide
|
C7H8N4O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0964230
|
(3-Chlorobenzo[b]thiophen-2-yl)methanamine
Show/Hide
|
C9H8ClNS
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0964642
|
Benzofuran-2-ylmethanamine
Show/Hide
|
C9H9NO
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0966378
|
(5-Chloro-1H-indol-2-yl)methanamine
Show/Hide
|
C9H9ClN2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0391797
|
(2-phenoxypyridin-4-yl)methanamine
Show/Hide
|
C12H12N2O
|
1
|
| 1 |
IC50 = 309 nM
|
|
|
|
CP0902472
|
(2-Phenoxypyridin-4-yl)methanamine Hydrochloride
Show/Hide
|
C12H13ClN2O
|
2
|
| 1 |
IC50 = 310 nM
|
|
|
| 2 |
IC50 = 860 nM
|
|
|
|
CP0536055
|
(2-pyridin-3-ylpyridin-4-yl)methanamine
Show/Hide
|
C11H11N3
|
1
|
| 1 |
IC50 = 321 nM
|
|
|
|
CP0455798
|
(2-fluoropyridin-4-yl)methanamine
Show/Hide
|
C6H7FN2
|
1
|
| 1 |
IC50 = 385 nM
|
|
|
|
CP0562927
|
(3-fluoropyridin-4-yl)methanamine
Show/Hide
|
C6H7FN2
|
1
|
| 1 |
IC50 = 431 nM
|
|
|
|
CP0903505
|
4-((4-(Aminomethyl)pyridin-2-yl)oxy)-N-(2-methoxyethyl)benzamide Hydrochloride
Show/Hide
|
C16H20ClN3O3
|
2
|
| 1 |
IC50 = 500 nM
|
|
|
| 2 |
IC50 = 1500 nM
|
|
|
|
CP0468820
|
(3R)-3-[4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl]oxy-N-phenylpiperidine-1-carboxamide
Show/Hide
|
C19H21F3N4O2
|
2
|
| 1 |
IC50 = 570 nM
|
|
|
| 2 |
IC50 = 620 nM
|
|
|
|
CP0419735
|
4-(aminomethyl)benzonitrile
Show/Hide
|
C8H8N2
|
1
|
| 1 |
IC50 = 670 nM
|
|
|
|
CP0549610
|
(4-nitrophenyl)methanamine
Show/Hide
|
C7H8N2O2
|
1
|
| 1 |
IC50 = 719 nM
|
|
|
|
CP0519353
|
(2-cyclohexyloxypyridin-4-yl)methanamine
Show/Hide
|
C12H18N2O
|
2
|
| 1 |
IC50 = 850 nM
|
|
|
| 2 |
IC50 = 1800 nM
|
|
|
|
CP0411206
|
[4-(1,3-thiazol-2-yl)phenyl]methanamine
Show/Hide
|
C10H10N2S
|
1
|
| 1 |
IC50 = 902 nM
|
|
|
|
CP0457290
|
[2-(trifluoromethyl)pyridin-4-yl]methanamine
Show/Hide
|
C7H7F3N2
|
1
|
| 1 |
IC50 = 999 nM
|
|
|
|
CP0915195
|
4-(Aminomethyl)-2-(trifluoromethyl)pyridine Hydrochloride
Show/Hide
|
C7H8ClF3N2
|
2
|
| 1 |
IC50 = 1000 nM
|
|
|
| 2 |
IC50 = 1400 nM
|
|
|
|
CP0244687
|
4-(aminomethyl)benzenecarboximidamide
Show/Hide
|
C22H27FN2O3
|
1
|
| 1 |
IC50 = 1110 nM
|
|
|
|
CP0518797
|
(2-methoxypyridin-4-yl)methanamine
Show/Hide
|
C7H10N2O
|
3
|
| 1 |
IC50 = 1180 nM
|
|
|
| 2 |
IC50 = 1200 nM
|
|
|
| 3 |
IC50 = 1400 nM
|
|
|
|
CP0548987
|
pyridin-4-ylmethanamine
Show/Hide
|
C6H8N2
|
1
|
| 1 |
IC50 = 1220 nM
|
|
|
|
CP0432798
|
(3-(Methoxycarbonyl)Phenyl)Methanaminium
Show/Hide
|
C9H11NO2
|
1
|
| 1 |
IC50 = 3540 nM
|
|
|
|
CP0100530
|
methyl 4-(aminomethyl)benzoate
Show/Hide
|
C9H11NO2
|
1
|
| 1 |
IC50 = 3620 nM
|
|
|
|
CP0547168
|
3-(aminomethyl)benzenecarboximidamide
Show/Hide
|
C8H11N3
|
1
|
| 1 |
IC50 = 4970 nM
|
|
|
|
CP0570385
|
quinolin-4-ylmethanamine
Show/Hide
|
C10H10N2
|
1
|
| 1 |
IC50 = 6040 nM
|
|
|
|
CP0570387
|
2-pyridin-4-ylethanamine
Show/Hide
|
C7H10N2
|
1
|
| 1 |
IC50 = 8210 nM
|
|
|
|
CP0049231
|
4-Fluoro-benzylamine
Show/Hide
|
C7H8FN
|
1
|
| 1 |
IC50 = 26000 nM
|
|
|
|
CP0413661
|
[2-pyridin-3-yl-5-(trifluoromethyl)pyridin-4-yl]methanamine
Show/Hide
|
C12H10F3N3
|
1
|
| 1 |
IC50 > 31000 nM
|
|
|
|
CP0402791
|
4-(methylaminomethyl)benzonitrile
Show/Hide
|
C9H10N2
|
1
|
| 1 |
IC50 = 35000 nM
|
|
|
|
CP0212470
|
4-(aminomethyl)aniline
Show/Hide
|
C7H10N2
|
1
|
| 1 |
IC50 = 47000 nM
|
|
|
|
CP0061725
|
14C-phenylethylamine
Show/Hide
|
C8H11N
|
1
|
| 1 |
IC50 = 60100 nM
|
|
|
|
CP0037372
|
Benzenemethanamine
Show/Hide
|
C7H9N
|
1
|
| 1 |
IC50 = 64700 nM
|
|
|
|
CP0536056
|
4-(aminomethyl)-N-methylaniline
Show/Hide
|
C8H12N2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0640830
|
tranylcypromine
Show/Hide
|
C18H22N2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0550687
|
Compound 1-5
Show/Hide
|
C19H16F3N3O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0553943
|
Compound 1-28
Show/Hide
|
C19H19F3N4O4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0553944
|
Compound 1-57
Show/Hide
|
C26H30F3N5O4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0556652
|
Compound 1-58
Show/Hide
|
C15H12F3N3O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0561470
|
Compound 1-169
Show/Hide
|
C18H14F3N3O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0874547
|
(3-(1H-Pyrazol-1-yl)azetidin-1-yl)(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)methanone trifluoroacetate
Show/Hide
|
C22H19F6N5O4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0874548
|
N-(2-(1H-1,2,4-Triazol-1-yl)ethyl)-3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzamide hydrochloride
Show/Hide
|
C18H18ClF3N6O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0874549
|
Rac-trans-(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(-3-(dimethylamino)-4-hydroxypyrrolidin-1-yl)methanone hydrochloride
Show/Hide
|
C20H24ClF3N4O3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0874551
|
3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(2-(dimethylamino)ethyl)benzamide dihydrochloride
Show/Hide
|
C18H23Cl2F3N4O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0874552
|
(S)-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)piperidin-1-yl)(pyrimidin-5-yl)methanone trifluoroacetate
Show/Hide
|
C19H19F6N5O4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0874553
|
3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-((1-hydroxycyclobutyl)methyl)benzamide hydrochloride
Show/Hide
|
C19H21ClF3N3O3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0874554
|
Rac-cis-(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(3-fluoro-4-hydroxypyrrolidin-1-yl)methanone hydrochloride
Show/Hide
|
C18H18ClF4N3O3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0874557
|
Rac-trans-(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-4-(benzyloxy)phenyl)(3-fluoro-4-hydroxypyrrolidin-1-yl)methanone
Show/Hide
|
C25H23F4N3O4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0874558
|
(3R,4S)/(3S,4R)-cis-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(3-fluoro-4-hydroxypyrrolidin-1-yl)methanone hydrochloride
Show/Hide
|
C18H18ClF4N3O3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0883982
|
3-(((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)amino)methyl)-N-phenylbenzamide hydrochloride
Show/Hide
|
C21H20ClF3N4O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0887836
|
3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(4-ethylphenyl)benzamide hydrochloride
Show/Hide
|
C22H21ClF3N3O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0900045
|
3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(2-hydroxyethyl)benzamide hydrochloride
Show/Hide
|
C16H17ClF3N3O3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0900046
|
(S)-2-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)piperidine-1-carbonyl)-4H-chromen-4-one trifluoroacetate
Show/Hide
|
C24H21F6N3O6
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0901641
|
(R,R)-trans-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(3-fluoro-4-hydroxypyrrolidin-1-yl)methanone hydrochloride
Show/Hide
|
C18H19Cl2F4N3O3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0901642
|
8-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzoyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride
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C21H22ClF3N4O4
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1
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| 1 |
IC50 < 300 nM
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CP0901643
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(S)-3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-phenylpyrrolidine-1-carboxamide trifluoroacetate
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C20H20F6N4O4
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1
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| 1 |
IC50 < 300 nM
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CP0901644
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(S)-1-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)piperidin-1-yl)-2-methylpropan-1-one trifluoroacetate
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C18H23F6N3O4
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1
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| 1 |
IC50 < 300 nM
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CP0901645
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(R)-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(3-fluoropyrrolidin-1-yl)methanone hydrochloride
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C18H18ClF4N3O2
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1
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| 1 |
IC50 < 300 nM
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CP0901646
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(oxazol-2-yl)benzamide hydrochloride
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C17H14ClF3N4O3
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1
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| 1 |
IC50 < 300 nM
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CP0903881
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(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(3,4-dihydroisoquinolin-2(1H)-yl)methanone hydrochloride
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C23H21ClF3N3O2
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1
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| 1 |
IC50 < 300 nM
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CP0903882
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Rac-trans-(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(3-fluoro-4-hydroxypyrrolidin-1-yl)methanone hydrochloride
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C18H18ClF4N3O3
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1
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| 1 |
IC50 < 300 nM
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CP0903884
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5-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(2-(methylsulfonyl)ethyl)nicotinamide hydrochloride
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C16H18ClF3N4O4S
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1
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| 1 |
IC50 < 300 nM
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CP0903885
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Rac-trans-(5-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)pyridin-3-yl)(-3-fluoro-4-hydroxypyrrolidin-1-yl)methanone hydrochloride
Show/Hide
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C17H17ClF4N4O3
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1
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| 1 |
IC50 < 300 nM
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CP0903886
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(2-((1-(1-Methyl-1H-pyrazol-4-yl)-1H-indol-4-yl)oxy)-6-(trifluoromethyl)pyridin-4-yl)methanamine hydrochloride
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C19H17ClF3N5O
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1
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| 1 |
IC50 < 300 nM
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CP0903888
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(2-cyanoethyl)benzamide hydrochloride
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C17H16ClF3N4O2
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1
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| 1 |
IC50 < 300 nM
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CP0903889
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(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(7-oxa-2-azaspiro[3.5]nonan-2-yl)methanone hydrochloride
Show/Hide
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C21H23ClF3N3O3
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1
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| 1 |
IC50 < 300 nM
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CP0903890
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-((1S,2R)-2-hydroxycyclopentyl)benzamide hydrochloride
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C19H21ClF3N3O3
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1
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| 1 |
IC50 < 300 nM
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CP0903891
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(3R,4R)-1-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzoyl)-4-fluoropyrrolidin-3-ylmethanesulfonate hydrochloride
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C19H20ClF4N3O5S
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1
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| 1 |
IC50 < 300 nM
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CP0903892
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Methyl (S)-3-(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzamido)pent-4-ynoate
Show/Hide
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C20H18F3N3O4
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1
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| 1 |
IC50 < 300 nM
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CP0903893
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Methyl (R)-3-(3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzamido)pent-4-ynoate hydrochloride
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C20H19ClF3N3O4
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1
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| 1 |
IC50 < 300 nM
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CP0903897
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)thio)-N-phenylbenzamide hydrochloride
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C20H17ClF3N3OS
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1
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| 1 |
IC50 < 300 nM
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CP0903898
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N1-(4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)-N3-(2-(methylsulfonyl)ethyl)isophthalamide trifluoroacetate
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C20H20F6N4O6S
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1
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| 1 |
IC50 < 300 nM
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CP0903899
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)carbamoyl)benzoic acid trifluoroacetate
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C17H13F6N3O5
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1
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| 1 |
IC50 < 300 nM
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CP0903901
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(3-ethynylphenyl)benzamide hydrochloride
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C22H17ClF3N3O2
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1
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| 1 |
IC50 < 300 nM
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CP0903902
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4-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-phenylpicolinamide hydrochloride
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C19H16ClF3N4O2
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1
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| 1 |
IC50 < 300 nM
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CP0905683
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(R)-(5-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)pyridin-3-yl)(3-aminopyrrolidin-1-yl)methanone dihydrochloride
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C17H20Cl2F3N5O2
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1
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| 1 |
IC50 < 300 nM
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CP0905684
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3-(((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)amino)methyl)-N-(2-(methylsulfonyl)ethyl)benzamide hydrochloride
Show/Hide
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C18H22ClF3N4O3S
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1
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| 1 |
IC50 < 300 nM
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CP0905687
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(4-methyl-2-oxo-2H-chromen-7-yl)benzamide hydrochloride
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C24H19ClF3N3O4
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1
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| 1 |
IC50 < 300 nM
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CP0909949
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(S)-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)piperidin-1-yl)(pyridin-3-yl)methanone trifluoroacetate
Show/Hide
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C20H20F6N4O4
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1
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| 1 |
IC50 < 300 nM
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CP0909951
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(4-(1-phenyl-1H-1,2,3-triazol-4-yl)butyl)benzamide hydrochloride
Show/Hide
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C26H26ClF3N6O2
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1
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| 1 |
IC50 < 300 nM
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CP0946493
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(4-fluorobenzyl)benzamide hydrochloride
Show/Hide
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C21H18ClF4N3O2
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1
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| 1 |
IC50 < 300 nM
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CP0946494
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(2-(methylsulfonyl)ethyl)benzamide hydrochloride
Show/Hide
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C17H19ClF3N3O4S
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1
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| 1 |
IC50 < 300 nM
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CP0946519
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1-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzoyl)azetidine-3-carbonitrile trifluoroacetate
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C20H16F6N4O4
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1
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| 1 |
IC50 < 300 nM
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CP0953803
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5-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-3,4-dihydroquinolin-2(1H)-one hydrochloride
Show/Hide
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C16H15ClF3N3O2
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1
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| 1 |
IC50 < 300 nM
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CP0953804
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(2-(3-(1H-Pyrazol-4-yl)phenoxy)-6-(trifluoromethyl)pyridin-4-yl)methanamine trifluoroacetate
Show/Hide
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C18H14F6N4O3
|
1
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| 1 |
IC50 < 300 nM
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CP0954542
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(oxetan-3-yl)benzamide trifluoroacetate
Show/Hide
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C19H17F6N3O5
|
1
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| 1 |
IC50 < 300 nM
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CP0954737
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(2-hydroxyethyl)-N-methylbenzamide hydrochloride
Show/Hide
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C17H19ClF3N3O3
|
1
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| 1 |
IC50 < 300 nM
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CP0954738
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(S)-N-(4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)-3-(3-hydroxypyrrolidine-1-carbonyl)benzamide trifluoroacetate
Show/Hide
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C21H20F6N4O5
|
1
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| 1 |
IC50 < 300 nM
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CP0956606
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(2-(3-(Phenoxymethyl)phenoxy)-6-(trifluoromethyl)pyridin-4-yl)methanamine trifluoroacetate
Show/Hide
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C22H18F6N2O4
|
1
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| 1 |
IC50 < 300 nM
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CP0956835
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Rac-3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-((5-oxopyrrolidin-2-yl)methyl)benzamide hydrochloride
Show/Hide
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C19H20ClF3N4O3
|
1
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| 1 |
IC50 < 300 nM
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CP0956836
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(2-hydroxy-2-methylpropyl)benzamide hydrochloride
Show/Hide
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C18H21ClF3N3O3
|
1
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| 1 |
IC50 < 300 nM
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CP0956839
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(6-(Trifluoromethyl)-[2,3'-bipyridin]-4-yl)methanamine trifluoroacetate
Show/Hide
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C14H11F6N3O2
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1
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| 1 |
IC50 < 300 nM
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CP0956840
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(S)-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(3-(hydroxymethyl)piperidin-1-yl)methanone hydrochloride
Show/Hide
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C20H23ClF3N3O3
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1
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| 1 |
IC50 < 300 nM
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CP0956841
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(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(4-(hydroxymethyl)piperidin-1-yl)methanone hydrochloride
Show/Hide
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C20H23ClF3N3O3
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1
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| 1 |
IC50 < 300 nM
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CP0956842
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)methyl)-1-benzyl-6-methylpyrimidine-2,4(1H,3H)-dione hydrochloride
Show/Hide
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C20H20ClF3N4O2
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1
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| 1 |
IC50 < 300 nM
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CP0957800
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N-((2H-Tetrazol-5-yl)methyl)-3-((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzamide hydrochloride
Show/Hide
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C16H15ClF3N7O2
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1
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| 1 |
IC50 < 300 nM
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CP0958094
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(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(3-(methoxymethyl)azetidin-1-yl)methanone hydrochloride
Show/Hide
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C19H21ClF3N3O3
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1
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| 1 |
IC50 < 300 nM
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CP0958095
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-((1R,2S)-2-hydroxycyclopentyl)benzamide hydrochloride
Show/Hide
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C19H21ClF3N3O3
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1
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| 1 |
IC50 < 300 nM
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CP0958096
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Rac-trans-(3-(4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yloxy)-5-hydroxyphenyl)(3-fluoro-4-hydroxypyrrolidin-1-yl)methanone hydrochloride
Show/Hide
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C18H18ClF4N3O4
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1
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| 1 |
IC50 < 300 nM
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CP0959182
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(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(2,5-dihydro-1H-pyrrol-1-yl)methanone hydrochloride
Show/Hide
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C18H17ClF3N3O2
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1
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| 1 |
IC50 < 300 nM
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CP0960246
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(1,3,4-oxadiazol-2-yl)benzamide hydrochloride
Show/Hide
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C16H13ClF3N5O3
|
1
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| 1 |
IC50 < 300 nM
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CP0961693
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(pyrimidin-5-yl)benzamide hydrochloride
Show/Hide
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C18H15ClF3N5O2
|
1
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| 1 |
IC50 < 300 nM
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CP0961696
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(1-(hydroxymethyl)cyclopropyl)benzamide hydrochloride
Show/Hide
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C18H19ClF3N3O3
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1
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| 1 |
IC50 < 300 nM
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CP0961697
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3-((4-(Aminomethyl-d2)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-phenylbenzamide hydrochloride
Show/Hide
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C20H17ClF3N3O2
|
1
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| 1 |
IC50 < 300 nM
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CP0961698
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(R)-3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-phenylpyrrolidine-1-carboxamide trifluoroacetate
Show/Hide
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C20H20F6N4O4
|
1
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| 1 |
IC50 < 300 nM
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CP0961700
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(S)-1-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)piperidin-1-yl)-2-phenylethanone trifluoroacetate
Show/Hide
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C22H23F6N3O4
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1
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| 1 |
IC50 < 300 nM
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CP0961701
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4-(((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)methyl)-N-phenylpiperidine-1-carboxamide trifluoroacetate
Show/Hide
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C22H24F6N4O4
|
1
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| 1 |
IC50 < 300 nM
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CP0961712
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(S)-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(3-hydroxypyrrolidin-1-yl)methanone hydrochloride
Show/Hide
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C18H19ClF3N3O3
|
1
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| 1 |
IC50 < 300 nM
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CP0961713
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(R)-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(3-(hydroxymethyl)pyrrolidin-1-yl)methanone hydrochloride
Show/Hide
|
C19H21ClF3N3O3
|
1
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| 1 |
IC50 < 300 nM
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CP0961761
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(2-([1,1'-Biphenyl]-3-yloxy)-6-(trifluoromethyl)pyridin-4-yl)methanamine trifluoroacetate
Show/Hide
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C21H16F6N2O3
|
1
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| 1 |
IC50 < 300 nM
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CP0961772
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(S)-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(3-fluoropyrrolidin-1-yl)methanone hydrochloride
Show/Hide
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C18H18ClF4N3O2
|
1
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| 1 |
IC50 < 300 nM
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CP0961784
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(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(4-hydroxy-4-methylpiperidin-1-yl)methanone hydrochloride
Show/Hide
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C20H23ClF3N3O3
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1
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| 1 |
IC50 < 300 nM
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CP0961785
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methyl 3-(4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-ylcarbamoyl)benzoate trifluoroacetate
Show/Hide
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C18H15F6N3O5
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1
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| 1 |
IC50 < 300 nM
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CP0968625
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Rac-trans-(3-(((4-(aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)methyl)phenyl)(3-fluoro-4-hydroxypyrrolidin-1-yl)methanone hydrochloride
Show/Hide
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C19H20ClF4N3O3
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1
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| 1 |
IC50 < 300 nM
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CP0968626
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(S)-3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-phenylpiperidine-1-carboxamide trifluoroacetate
Show/Hide
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C21H22F6N4O4
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1
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| 1 |
IC50 < 300 nM
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CP0968627
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2-(4-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-1H-indol-1-yl)-N-methyl-N-phenylacetamide hydrochloride
Show/Hide
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C24H22ClF3N4O2
|
1
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| 1 |
IC50 < 300 nM
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CP0968628
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(2-(3-Phenoxyphenoxy)-6-(trifluoromethyl)pyridin-4-yl)methanamine trifluoroacetate
Show/Hide
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C21H16F6N2O4
|
1
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| 1 |
IC50 < 300 nM
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CP0969050
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(3-ethylphenyl)benzamide hydrochloride
Show/Hide
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C22H21ClF3N3O2
|
1
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| 1 |
IC50 < 300 nM
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CP0969447
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(prop-2-yn-1-yl)benzamide hydrochloride
Show/Hide
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C17H15ClF3N3O2
|
1
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| 1 |
IC50 < 300 nM
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CP0969776
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(hex-5-yn-1-yl)benzamide trifluoroacetate
Show/Hide
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C22H21F6N3O4
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1
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| 1 |
IC50 < 300 nM
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CP0969777
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-(2-aminophenyl)benzamide hydrochloride
Show/Hide
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C20H18ClF3N4O2
|
1
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| 1 |
IC50 < 300 nM
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CP0969807
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3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-N-((3S,4S)-4-hydroxytetrahydro-2H-pyran-3-yl)benzamide hydrochloride
Show/Hide
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C19H21ClF3N3O4
|
1
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| 1 |
IC50 < 300 nM
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CP0970145
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N1-(4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)-N3-phenylisophthalamide trifluoroacetate
Show/Hide
|
C28H27F6N3O6
|
1
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| 1 |
IC50 < 300 nM
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CP0970153
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(S)-1-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)piperidin-1-yl)-2-(3,4-dichlorophenyl)ethanone trifluoroacetate
Show/Hide
|
C22H21Cl2F6N3O4
|
1
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| 1 |
IC50 < 300 nM
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CP0382920
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2-(aminomethyl)-6-(phenylethynyl)quinolin-4(1H)-one hydrochloride
Show/Hide
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C18H14N2O
|
1
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| 1 |
IC50 < 300 nM
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CP0382921
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2-(aminomethyl)-6-phenylquinolin-4(1H)-one hydrochloride
Show/Hide
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C16H14N2O
|
1
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| 1 |
IC50 < 300 nM
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CP0382922
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2-(aminomethyl)-6-ethynvlquinolin-4(1H)-one hydrochloride
Show/Hide
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C12H10N2O
|
1
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| 1 |
IC50 < 300 nM
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CP0402372
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2-(aminomethyl)quinolin-4(1H)-one hydrochloride
Show/Hide
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C10H10N2O
|
1
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| 1 |
IC50 < 300 nM
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CP0421537
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2-(aminomethyl)-6-(2-methoxyethoxy)quinolin-4(1)-one hydrochloride
Show/Hide
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C13H16N2O3
|
1
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| 1 |
IC50 < 300 nM
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CP0421538
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2-(aminomethyl)-6-(2-(trifluoromethyl)pyrimidin-5-yl)quinolin-4(1H)-one hydrochloride
Show/Hide
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C15H11F3N4O
|
1
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| 1 |
IC50 < 300 nM
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CP0421539
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2-(aminomethyl)-6-(2-chloro-4-fluorophenyl)quinolin-4(1H)-one hydrochloride
Show/Hide
|
C16H12ClFN2O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0421540
|
2-(aminomethyl)-6-(1-phenyl-1H-1,2,3-triazol-4-yl)quinolin-4(1H)-one hydrochloride
Show/Hide
|
C18H15N5O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0437717
|
2-(aminomethyl)-6-(6-(trifluoromethyl)pyridin-3-yl)quinolin-4(1H)-one hydrochloride
Show/Hide
|
C16H12F3N3O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0437718
|
2-(aminomethyl)-6-(4-fluorophenyl)quinolin-4(1H)-one hydrochloride
Show/Hide
|
C16H13FN2O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0437719
|
2-(aminomethyl)-6-bromoquinolin-4(1H)-one hydrochloride
Show/Hide
|
C10H9BrN2O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0440311
|
2-(aminomethyl)-6-phenoxyquinolin-4(1H)-one hydrochloride
Show/Hide
|
C16H14N2O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0459758
|
2-(aminomethyl)-6-(1-methyl-1H-pyrazol-4-yl)quinolin-4(1H)-one hydrochloride
Show/Hide
|
C14H14N4O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0474169
|
2-(aminomethyl)-6-(pyrimidin-5-yl)quinolin-4(1H)-one hydrochloride
Show/Hide
|
C14H12N4O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0524556
|
2-(aminomethyl)-6-(3-fluoro-4-methoxyphenyl)quinolin-4(1H)-one hydrochloride
Show/Hide
|
C17H15FN2O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0536373
|
2-(aminomethyl)-6-(5-(benzyloxy)pyridin-3-yl)quinolin-4(1H)-one hydrochloride
Show/Hide
|
C22H19N3O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0536374
|
2-(aminomethyl)-6-(5-methyl-2-oxopyridin-1(2H)-yl)quinolin-4(1H)-one hydrochloride
Show/Hide
|
C16H15N3O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0548754
|
2-(aminomethyl)-[6,8′-biquinolin]-4(1H)-one hydrochloride
Show/Hide
|
C19H15N3O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0559508
|
2-(aminomethyl)-6-methoxyquinolin-4(1H)-one hydrochloride
Show/Hide
|
C11H12N2O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0565204
|
2-(aminomethyl)-6-(1H-pyrazol-1-yl)quinolin-4(1U)-one hydrochloride
Show/Hide
|
C13H12N4O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0853186
|
2-(Aminomethyl)-6-methoxy-4H-chromen-4-one hydrochloride
Show/Hide
|
C11H12ClNO3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0853187
|
2-(Aminomethyl)-7-methoxy-4H-chromen-4-one hydrochloride
Show/Hide
|
C11H12ClNO3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0853188
|
2-(Aminomethyl)-7-(4-phenylpiperazin-1-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C20H22ClN3O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0853196
|
2-(Aminomethyl)-7-(2-phenoxyethoxy)-4H-chromen-4-one hydrochloride
Show/Hide
|
C18H18ClNO4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0853197
|
3-((2-(Aminomethyl)-4-oxo-4H-chromen-7-yl)oxy)-N-phenylbenzamide hydrochloride
Show/Hide
|
C23H19ClN2O4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0853198
|
2-(Aminomethyl)-7-(benzo[b]thiophen-2-ylmethoxy)-4H-chromen-4-one hydrochloride
Show/Hide
|
C19H16ClNO3S
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0874604
|
2-(Aminomethyl)-7-(1H-pyrazol-1-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C13H12ClN3O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0887775
|
2-(Aminomethyl)-6-(3-hydroxy-3-methylbut-1-yn-1-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C15H16ClNO3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0887777
|
2-(Aminomethyl)-6-phenyl-4H-chromen-4-one hydrochloride
Show/Hide
|
C16H14ClNO2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0946059
|
2-(Aminomethyl)-6-(3-methylbut-3-en-1-yn-1-yl)-4H-chromen-4-one trifluoroacetate
Show/Hide
|
C17H14F3NO4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0946060
|
2-(aminomethyl)-6-(quinolin-3-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C19H15ClN2O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0946061
|
2-(aminomethyl)-6-(1H-pyrazol-1-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C13H12ClN3O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0946321
|
2-(Aminomethyl)-7-(1-phenyl-1H-1,2,3-triazol-4-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C18H15ClN4O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0948451
|
2-(Aminomethyl)-6-(1-methyl-1H-1,2,3-triazol-4-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C13H13ClN4O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0949900
|
2-(Aminomethyl)-7-(prop-2-yn-1-yloxy)-4H-chromen-4-one hydrochloride
Show/Hide
|
C13H12ClNO3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0949901
|
2-(Aminomethyl)-7-(quinolin-2-ylmethoxy)-4H-chromen-4-one hydrochloride
Show/Hide
|
C20H17ClN2O3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0949902
|
2-(Aminomethyl)-7-(benzyloxy)-6-methoxy-4H-chromen-4-one hydrochloride
Show/Hide
|
C17H16ClNO4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0954992
|
2-(Aminomethyl)-6-(benzyloxy)-4H-chromen-4-one hydrochloride
Show/Hide
|
C17H16ClNO3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0954995
|
2-(Aminomethyl)-7-((3-phenylprop-2-yn-1-yl)oxy)-4H-chromen-4-one hydrochloride
Show/Hide
|
C19H16ClNO3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0955475
|
2-(Aminomethyl)-6-(1-phenyl-1H-1,2,3-triazol-4-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C18H15ClN4O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0955478
|
2-(Aminomethyl)-7-(3,4-dihydroquinolin-1(2H)-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C19H19ClN2O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0955479
|
2-(Aminomethyl)-7-((1-phenyl-1H-1,2,3-triazol-4-yl)methoxy)-4H-chromen-4-one hydrochloride
Show/Hide
|
C19H17ClN4O3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0955937
|
2-(Aminomethyl)-6-ethynyl-4H-chromen-4-one hydrochloride
Show/Hide
|
C12H10ClNO2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0956956
|
2-(Aminomethyl)-6-(1-methyl-1H-pyrazol-4-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C14H14ClN3O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0956957
|
2-(4-(2-(Aminomethyl)-4-oxo-4H-chromen-6-yl)-1H-1,2,3-triazol-1-yl)-N,N-dimethylacetamide hydrochloride
Show/Hide
|
C16H18ClN5O3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0956959
|
3-(((2-(Aminomethyl)-4-oxo-4H-chromen-7-yl)oxy)methyl)-N-phenylbenzamide hydrochloride
Show/Hide
|
C24H21ClN2O4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0957739
|
2-(Aminomethyl)-7-((4-(trifluoromethyl)benzyl)oxy)-4H-chromen-4-one hydrochloride
Show/Hide
|
C18H15ClF3NO3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0960865
|
2-(Aminomethyl)-7-((4-methoxybenzyl)oxy)-4H-chromen-4-one hydrochloride
Show/Hide
|
C18H18ClNO4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0960879
|
2-(Aminomethyl)-7-((1-phenyl-1H-pyrazol-4-yl)amino)-4H-chromen-4-one hydrochloride
Show/Hide
|
C19H17ClN4O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0961401
|
2-(Aminomethyl)-6-(1-benzyl-1H-1,2,3-triazol-4-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C19H17ClN4O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0961405
|
2-(Aminomethyl)-7-(1-methyl-1H-1,2,3-triazol-4-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C13H13ClN4O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0961406
|
2-(Aminomethyl)-7-isobutoxy-4H-chromen-4-one hydrochloride
Show/Hide
|
C14H18ClNO3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0961409
|
2-(Aminomethyl)-7-(3-(trifluoromethyl)phenoxy)-4H-chromen-4-one hydrochloride
Show/Hide
|
C17H13ClF3NO3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0961410
|
2-(Aminomethyl)-7-phenoxy-4H-chromen-4-one hydrochloride
Show/Hide
|
C16H14ClNO3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0961416
|
2-(Aminomethyl)-7-bromo-4H-chromen-4-one hydrochloride
Show/Hide
|
C10H9BrClNO2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0962248
|
2-(Aminomethyl)-6-(pyridin-2-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C15H13ClN2O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0964043
|
2-(Aminomethyl)-6-bromo-4H-chromen-4-one hydrochloride
Show/Hide
|
C10H9BrClNO2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0968210
|
2-(Aminomethyl)-6-(pyridin-3-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C15H13ClN2O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0968909
|
2-(Aminomethyl)-7-(4-benzoylpiperazin-1-yl)-4H-chromen-4-one hydrochloride
Show/Hide
|
C21H22ClN3O3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0969647
|
2-(Aminomethyl)-7-(benzyloxy)-4H-chromen-4-one hydrochloride
Show/Hide
|
C17H16ClNO3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0071155
|
1H-benzimidazol-2-ylmethanamine
Show/Hide
|
C8H9N3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0303199
|
2-ethyl-1H-indene
Show/Hide
|
C8H8N2S
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0874432
|
(5-Bromo-7-methylbenzofuran-2-yl)methanamine
Show/Hide
|
C10H10BrNO
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0903529
|
3-(6-(Aminomethyl)-1H-imidazo[4,5-c]pyridin-1-yl)-N-phenylbenzamide
Show/Hide
|
C20H17N5O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0903531
|
3-((7-(Aminomethyl)imidazo[1,2-a]pyrimidin-5-yl)amino)-N-phenylbenzamide
Show/Hide
|
C20H18N6O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0903532
|
3-((5-(Aminomethyl)pyridazin-3-yl)oxy)-N-phenylbenzamide
Show/Hide
|
C18H16N4O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0903533
|
2-(Aminomethyl)-6-bromo-4H-thiochromen-4-one
Show/Hide
|
C10H8BrNOS
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0903536
|
(1H-Naphtho[2,3-d]imidazol-2-yl)methanamine
Show/Hide
|
C12H11N3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0903537
|
(5-(tert-Butyl)benzo[d]oxazol-2-yl)methanamine
Show/Hide
|
C12H16N2O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0903540
|
(5-Bromo-1H-indol-2-yl)methanamine
Show/Hide
|
C9H9BrN2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0910032
|
3-(Aminomethyl)-7-(quinolin-3-yl)isoquinolin-1(2H)-one
Show/Hide
|
C19H15N3O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0910033
|
3-(Aminomethyl)-7-phenylisoquinolin-1(2H)-one
Show/Hide
|
C16H14N2O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0910035
|
(1H-Pyrrolo[2,3-c]pyridin-2-yl)methanamine
Show/Hide
|
C8H9N3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0941857
|
3-(Aminomethyl)-7-(4-bromo-1H-pyrazol-1-yl)isoquinolin-1(2H)-one
Show/Hide
|
C13H11BrN4O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0941858
|
3-(Aminomethyl)-7-methoxyisoquinolin-1(2H)-one
Show/Hide
|
C11H12N2O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0941860
|
(5-(tert-Butyl)benzo[b]thiophen-2-yl)methanamine
Show/Hide
|
C13H17NS
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0944957
|
5-(2-(Aminomethyl)benzo[b]thiophen-6-yl)-N-phenylpicolinamide
Show/Hide
|
C21H17N3OS
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0944958
|
(6-(Pyridin-3-yl)benzo[b]thiophen-2-yl)methanamine
Show/Hide
|
C14H12N2S
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0944959
|
(5-(Pyridin-3-yl)benzo[b]thiophen-2-yl)methanamine
Show/Hide
|
C14H12N2S
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0946436
|
(Pyridazin-3-yl)methanamine
Show/Hide
|
C5H7N3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0946438
|
(1H-Pyrrolo[3,2-b]pyridin-2-yl)methanamine
Show/Hide
|
C8H9N3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0948219
|
(1H-Imidazo[4,5-b]pyridin-2-yl)methanamine
Show/Hide
|
C7H8N4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0948226
|
(5-Cyclopropylbenzo[b]thiophen-2-yl)methanamine
Show/Hide
|
C12H13NS
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0948227
|
(5-Fluorobenzo[b]thiophen-2-yl)methanamine
Show/Hide
|
C9H8FNS
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0948228
|
(5-(Isoquinolin-4-yl)-1H-indol-2-yl)methanamine
Show/Hide
|
C18H15N3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0951460
|
3-(Aminomethyl)-7-(4-fluorophenyl)isoquinolin-1(2H)-one
Show/Hide
|
C16H13FN2O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0951461
|
3-(Aminomethyl)-7-ethynylisoquinolin-1(2H)-one
Show/Hide
|
C12H10N2O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0951463
|
2-(5-Chlorobenzo[d]oxazol-2-yl)ethanamine
Show/Hide
|
C9H9ClN2O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0951466
|
(5-(6-Phenoxypyridin-3-yl)-1H-indol-2-yl)methanamine
Show/Hide
|
C20H17N3O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0951557
|
2-(5-Fluorobenzo[d]thiazol-2-yl)ethanamine
Show/Hide
|
C9H9FN2S
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0954675
|
2-(7-Chlorobenzo[d]oxazol-2-yl)ethanamine
Show/Hide
|
C9H9ClN2O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0956192
|
(5-Bromobenzo[b]thiophen-2-yl)methanamine
Show/Hide
|
C9H8BrNS
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0956193
|
(5-(Quinolin-3-yl)-1H-indol-2-yl)methanamine
Show/Hide
|
C18H15N3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0956194
|
Methyl5-(2-(aminomethyl)-1H-indol-5-yl)nicotinate
Show/Hide
|
C16H15N3O2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0961551
|
(5-Iodo-1H-indol-2-yl)methanamine
Show/Hide
|
C9H9IN2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0964641
|
5-(2-(Aminomethyl)benzo[b]thiophen-6-yl)-N-benzylnicotinamide
Show/Hide
|
C22H19N3OS
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0964643
|
(5-(Pyridin-3-yl)-1H-indol-2-yl)methanamine
Show/Hide
|
C14H13N3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0964644
|
(5-(Imidazo[1,2-a]pyridin-6-yl)-1H-indol-2-yl)methanamine
Show/Hide
|
C16H14N4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0966371
|
(Pyrazin-3-yl)methanamine
Show/Hide
|
C5H7N3
|
1
|
| 1 |
IC50 < 300 nM
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|
|
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CP0966372
|
3-((7-(Aminomethyl)imidazo[1,2-a]pyrimidin-5-yl)oxy)-N-phenylbenzamide
Show/Hide
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C20H17N5O2
|
1
|
| 1 |
IC50 < 300 nM
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|
|
|
CP0966373
|
2-(5-Chlorobenzo[d]thiazol-2-yl)ethanamine
Show/Hide
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C9H9ClN2S
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0966374
|
SID24839176
Show/Hide
|
C9H10N2S
|
1
|
| 1 |
IC50 < 300 nM
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|
|
|
CP0966375
|
(5-Chloro-1H-benzo[d]imidazol-2-yl)methanamine
Show/Hide
|
C8H8ClN3
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0966376
|
5-(2-(Aminomethyl)benzo[b]thiophen-6-yl)-N-phenylnicotinamide
Show/Hide
|
C21H17N3OS
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0966377
|
(6-Bromobenzo[b]thiophen-2-yl)methanamine
Show/Hide
|
C9H8BrNS
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0968992
|
3-(Aminomethyl)-7-(phenylethynyl)isoquinolin-1(2H)-one
Show/Hide
|
C18H14N2O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0968993
|
(6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)methanamine
Show/Hide
|
C7H7BrN4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0968994
|
(5-(1-Methyl-1H-benzo[d]imidazol-6-yl)-1H-indol-2-yl)methanamine
Show/Hide
|
C17H16N4
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0968995
|
(5-(4-Fluorophenyl)-1H-indol-2-yl)methanamine
Show/Hide
|
C15H13FN2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0969424
|
3-(Aminomethyl)-7-bromoisoquinolin-1(2H)-one
Show/Hide
|
C10H9BrN2O
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0969425
|
2-(Aminomethyl)naphthalene-1,4-dione
Show/Hide
|
C11H9NO2
|
1
|
| 1 |
IC50 < 300 nM
|
|
|
|
CP0874550
|
(S)-1-(3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)benzoyl)pyrrolidine-2-carboxylic acid hydrochloride
Show/Hide
|
C19H19ClF3N3O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0903896
|
2-(5-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetic acid hydrochloride
Show/Hide
|
C18H17ClF3N3O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0903900
|
4'-(Aminomethyl)-6'-(trifluoromethyl)-2H-[1,2'-bipyridin]-2-one hydrochloride
Show/Hide
|
C12H11ClF3N3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0961715
|
3-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)methyl)-1-(2-hydroxyethyl)-6-methylpyrimidine-2,4(1H,3H)-dione hydrochloride
Show/Hide
|
C15H18ClF3N4O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0961793
|
2-(4-((4-(Aminomethyl)-6-(trifluoromethyl)pyridin-2-yl)oxy)-1H-indol-1-yl)-N-carbamimidoylacetamide dihydrochloride
Show/Hide
|
C18H19Cl2F3N6O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0969734
|
(4-(6-(Aminomethyl)pyrimidin-4-yl)piperazin-1-yl)(phenyl)methanone hydrochloride
Show/Hide
|
C16H20ClN5O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0563465
|
2-(aminomethyl)-1-methylquinolin-4(1H-one hydrochloride
Show/Hide
|
C11H12N2O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0955476
|
2-(aminomethyl)-N,N-dimethyl-4-oxo-4H-chromene-6-carboxamide hydrochloride
Show/Hide
|
C13H15ClN2O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0957738
|
3-(((2-(Aminomethyl)-4-oxo-4H-chromen-8-yl)oxy)methyl)-N-phenylbenzamide hydrochloride
Show/Hide
|
C24H21ClN2O4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0961404
|
(R,S)-1-(2-(aminomethyl)-4-oxo-4H-chromene-6-carbonyl)pyrrolidine-3-carboxylic acid hydrochloride
Show/Hide
|
C16H17ClN2O5
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0961408
|
2-(Aminomethyl)-8-(2-phenoxyethoxy)-4H-chromen-4-one hydrochloride
Show/Hide
|
C18H18ClNO4
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0962249
|
Methyl (S)-1-(2-(aminomethyl)-4-oxo-4H-chromene-6-carbonyl)pyrrolidine-3-carboxylate hydrochloride
Show/Hide
|
C17H19ClN2O5
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0970003
|
2-(Aminomethyl)-8-ethynyl-4H-chromen-4-one hydrochloride
Show/Hide
|
C12H10ClNO2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0214049
|
(5-bromo-1-benzofuran-2-yl)methanamine
Show/Hide
|
C9H8BrNO
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0331652
|
2-(6-fluoro-1H-benzimidazol-2-yl)ethanamine
Show/Hide
|
C9H10FN3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0903527
|
(Quinolin-6-yl)methanamine
Show/Hide
|
C10H10N2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0903535
|
4-(Aminomethyl)quinolin-2(1H)-one
Show/Hide
|
C10H10N2O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0910036
|
2-(5-Chloro-1H-benzo[d]imidazol-2-yl)ethanamine
Show/Hide
|
C9H10ClN3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0944954
|
(Rac)-2-amino-1-(benzo[b]thiophen-2-yl)ethanol
Show/Hide
|
C10H11NOS
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0944956
|
2-(1H-Indol-2-yl)ethanamine
Show/Hide
|
C10H12N2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0948214
|
(Benzimidazol-5-yl)methanamine
Show/Hide
|
C8H9N3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0948218
|
Thieno[3,2-b]furan-5-ylmethanamine
Show/Hide
|
C7H7NOS
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0948230
|
(6-Fluoro-7-methyl-1H-indol-2-yl)methanamine
Show/Hide
|
C10H11FN2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0951462
|
2-([1,2,4]Triazolo[3,4-b][1,3,4]thiadiazol-6-yl)ethanamine
Show/Hide
|
C5H7N5S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0951464
|
2-(1H-Benzo[d]imidazol-2-yl)ethanamine
Show/Hide
|
C9H11N3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0951465
|
2-(Benzo[b]thiophen-2-yl)ethanamine
Show/Hide
|
C10H11NS
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0951559
|
(5-Fluoro-3-methylbenzofuran-2-yl)methanamine
Show/Hide
|
C10H10FNO
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0955152
|
(5-fluoro-1H-indol-2-yl)methanamine
Show/Hide
|
C9H9FN2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0956190
|
(1H-Pyrrolo[3,2-b]pyridin-5-yl)methanamine
Show/Hide
|
C8H9N3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0956191
|
2-(Benzofuran-2-yl)ethanamine
Show/Hide
|
C10H11NO
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0964229
|
3-((6-(Aminomethyl)-1H-imidazo[4,5-c]pyridin-1-yl)methyl)-N-phenylbenzamide
Show/Hide
|
C21H19N5O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0968436
|
(1-Methyl-1H-indol-2-yl)methanamine
Show/Hide
|
C10H12N2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0970097
|
Benzo[d]oxazol-2-ylmethanamine
Show/Hide
|
C8H8N2O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
