Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
 Cell Line Info 
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT04719 , Somatostatin receptor type 3
 Protein Info 
Gene Name SSTR3
Organism Mus musculus, Mouse
Protein Classification Membrane receptor
Uniprot ID P30935
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011
 Cell Line Info 
 Protein ID: PT04719
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0368917
 Compound Info 
3-[(1R,3S)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(1-methylpyrazol-4-yl)-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]-5-methyl-1,2,4-oxadiazole
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C27H23FN8O
  2
1
IC50 = 0.14 nM
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2
IC50 = 0.5 nM
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CP0756633
 Compound Info 
5-((1R,3R)-3-(4-(4-fluorophenyl)-1H-imidazol-2-yl)-1-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)nicotinicacid
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C30H24FN7O2
  1
1
IC50 = 0.16 nM
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CP0844603
 Compound Info 
Ethyl5-((1R,3R)-3-(4-(4-fluorophenyl)-1H-imidazol-2-yl)-1-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)nicotinate
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C32H28FN7O2
  1
1
IC50 = 0.35 nM
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CP0072718
 Compound Info 
3-[(1R,3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(1-methylpyrazol-4-yl)-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]-5-methyl-1,2,4-oxadiazole
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C27H23FN8O
  2
1
IC50 = 0.36 nM
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2
IC50 = 0.46 nM
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CP0673513
 Compound Info 
Ethyl 2-((1S,3R)-3-(4-(4-fluorophenyl)-1H-imidazol-2-yl)-1-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)isonicotinate
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C32H28FN7O2
  2
1
IC50 = 0.36 nM
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2
IC50 = 0.41 nM
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CP0857552
 Compound Info 
Ethyl6-((1S,3R)-3-(4-(4-fluorophenyl)-1H-imidazol-2-yl)-1-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)picolinate
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C32H28FN7O2
  2
1
IC50 = 0.41 nM
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2
IC50 = 0.58 nM
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CP0414056
 Compound Info 
(3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1,1-bis(1-methylpyrazol-4-yl)-2,3,4,9-tetrahydropyrido[3,4-b]indole
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C28H25FN8
  2
1
IC50 = 0.46 nM
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2
IC50 = 0.48 nM
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CP0330210
 Compound Info 
3-[(3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(5-methyl-1,2,4-oxadiazol-3-yl)-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]-5-methyl-1,2,4-oxadiazole
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C26H21FN8O2
  2
1
IC50 = 0.59 nM
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2
IC50 = 1.3 nM
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CP0120411
 Compound Info 
3-[(1S,3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(1-methylpyrazol-4-yl)-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]-5-methyl-1,2,4-oxadiazole
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C27H23FN8O
  2
1
IC50 = 0.61 nM
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2
IC50 = 3.7 nM
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CP0673514
 Compound Info 
Ethyl6-((1R,3R)-3-(4-(4-fluorophenyl)-1H-imidazol-2-yl)-1-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)picolinate
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C32H28FN7O2
  2
1
IC50 = 0.7 nM
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2
IC50 = 3.48 nM
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CP0237736
 Compound Info 
2-[(1R,3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(1-methylpyrazol-4-yl)-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyridine-4-carboxylic acid
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C30H24FN7O2
  2
1
IC50 = 0.73 nM
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2
IC50 = 1.72 nM
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CP0057457
 Compound Info 
3-[(1S,3S)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(1-methylpyrazol-4-yl)-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]-5-methyl-1,2,4-oxadiazole
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C27H23FN8O
  2
1
IC50 = 1.2 nM
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2
IC50 = 4.8 nM
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CP0651917
 Compound Info 
5-((1R,3R)-1-(1-ethyl-1H-pyrazol-4-yl)-3-(4-(5-fluoropyridin-2-yl)-1H-imidazol-2-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-3-methyl-1,3,4-oxadiazol-2(3H)-one
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C27H24FN9O2
  1
1
IC50 = 1.3 nM
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CP0381489
 Compound Info 
ethyl 6-[(1R,3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(1-methylpyrazol-4-yl)-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyridine-3-carboxylate
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C32H28FN7O2
  1
1
IC50 = 1.53 nM
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CP0140617
 Compound Info 
(1R,3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(oxan-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
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C25H25FN4O
  2
1
IC50 = 1.7 nM
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2
IC50 = 26 nM
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CP0305127
 Compound Info 
(3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1,1-diphenyl-2,3,4,9-tetrahydropyrido[3,4-b]indole
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C32H25FN4
  1
1
IC50 = 2.4 nM
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CP0857551
 Compound Info 
5-((1S,3R)-3-(4-(4-fluorophenyl)-1H-imidazol-2-yl)-1-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)nicotinicacid
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C30H24FN7O2
  1
1
IC50 = 2.9 nM
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CP0838810
 Compound Info 
6-((1S,3R)-3-(4-(4-fluorophenyl)-1H-imidazol-2-yl)-1-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)picolinicacid
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C30H24FN7O2
  2
1
IC50 = 3.93 nM
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2
IC50 = 34 nM
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CP0145754
 Compound Info 
(1R,3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(1-methylpyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
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C24H21FN6
  2
1
IC50 = 4 nM
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2
IC50 = 4.4 nM
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CP0283794
 Compound Info 
(1S,3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(1-methylpyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
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C24H21FN6
  2
1
IC50 = 4.8 nM
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2
IC50 = 26 nM
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CP0381316
 Compound Info 
3-[(1R,3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]-5-methyl-1,2,4-oxadiazole
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C23H19FN6O
  2
1
IC50 = 8.1 nM
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2
IC50 = 29 nM
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CP0396794
 Compound Info 
ethyl 5-[(1S,3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(1-methylpyrazol-4-yl)-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyridine-3-carboxylate
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C32H28FN7O2
  1
1
IC50 = 8.37 nM
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CP0076698
 Compound Info 
(1R,3R)-1-(oxan-4-yl)-3-(5-phenyl-1H-imidazol-2-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
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C25H26N4O
  2
1
IC50 = 8.9 nM
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2
IC50 = 16 nM
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CP0848007
 Compound Info 
ethyl6-((1R,3R)-3-(4-(4-fluorophenyl)-1H-imidazol-2-yl)-1-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)nicotinate
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C32H28FN7O2
  1
1
IC50 = 14.2 nM
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CP0362610
 Compound Info 
ethyl 2-[(1S,3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-1-(1-methylpyrazol-4-yl)-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]pyridine-4-carboxylate
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C32H28FN7O2
  1
1
IC50 = 14.7 nM
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CP0849068
 Compound Info 
2-((1R,3R)-3-(4-(4-fluorophenyl)-1H-imidazol-2-yl)-1-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)isonicotinicacid
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C30H24FN7O2
  1
1
IC50 = 17.1 nM
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CP0381407
 Compound Info 
3-[(1S,3R)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]-5-methyl-1,2,4-oxadiazole
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C23H19FN6O
  1
1
IC50 = 18 nM
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CP0727500
 Compound Info 
6-((1S,3R)-3-(4-(4-fluorophenyl)-1H-imidazol-2-yl)-1-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)nicotinicacid
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C30H24FN7O2
  1
1
IC50 = 57.1 nM
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CP0849099
 Compound Info 
6-((1R,3R)-3-(4-(4-fluorophenyl)-1H-imidazol-2-yl)-1-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)picolinicacid
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C30H24FN7O2
  1
1
IC50 = 111 nM
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CP0864058
 Compound Info 
6-((1R,3R)-3-(4-(4-fluorophenyl)-1H-imidazol-2-yl)-1-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)nicotinicacid
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C30H24FN7O2
  1
1
IC50 = 1863 nM
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