Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT04565 , Follicle-stimulating hormone receptor
Gene Name FSHR
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P23945
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT04565
 
Compound ID Compound Name Compound Formula
CP0431092
1-Butyl-1-[4'-((2S,5S)-1,5-dimethyl-4-octyl-3,6-dioxo-piperazin-2-ylmethyl)-biphenyl-3-ylmethyl]-3-methyl-urea
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C34H50N4O3
 1
1
EC50 = 7.9 nM
   TI
   LI
   LO
   TS
CP0402494
1-Butyl-1-[4'-((2S,5S)-4-hexyl-1,5-dimethyl-3,6-dioxo-piperazin-2-ylmethyl)-biphenyl-3-ylmethyl]-3-methyl-urea
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C32H46N4O3
 1
1
EC50 = 9.5 nM
   TI
   LI
   LO
   TS
CP0403948
Butyl-[4'-((2S,5S)-1,5-dimethyl-4-octyl-3,6-dioxo-piperazin-2-ylmethyl)-biphenyl-3-ylmethyl]-carbamic acid methyl ester
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C34H49N3O4
 1
1
EC50 = 31 nM
   TI
   LI
   LO
   TS
CP0375846
(3S,6S)-1,3-Dimethyl-4-octyl-6-(3',4',5'-trimethoxy-biphenyl-4-ylmethyl)-piperazine-2,5-dione
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C30H42N2O5
 1
1
EC50 = 32 nM
   TI
   LI
   LO
   TS
CP0532380
N-butyl-N-[[3-[4-[[(2S,5S)-1,5-dimethyl-4-octyl-3,6-dioxopiperazin-2-yl]methyl]phenyl]phenyl]methyl]acetamide
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C34H49N3O3
 1
1
EC50 = 35 nM
   TI
   LI
   LO
   TS
CP0403495
2-cyclopropyl-N-[2-[4-(2-methylphenyl)piperazin-1-yl]-5-[3-(2H-tetrazol-5-yl)propylcarbamoyl]phenyl]-1,3-oxazole-4-carboxamide
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C29H33N9O3
 2
1
EC50 < 100 nM
   TI
   LI
   LO
   TS
2
EC50 = 89000 nM
   TI
   LI
   LO
   TS
CP0414651
3-[(4-fluorobenzoyl)amino]-4-[4-(2-methylphenyl)piperazin-1-yl]-N-[3-(2-oxopyrrolidin-1-yl)propyl]benzamide
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C32H36FN5O3
 1
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
CP0420161
N-[2-[4-(2-methylphenyl)piperazin-1-yl]-5-[3-(prop-2-enylcarbamoylamino)propylcarbamoyl]phenyl]furan-2-carboxamide
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C30H36N6O4
 1
1
EC50 < 100 nM
   TI
   LI
   LO
   TS
CP0452359
2-cyclopropyl-N-[2-[4-(2-methylphenyl)piperazin-1-yl]-5-[3-(2-oxopyrrolidin-1-yl)propylcarbamoyl]phenyl]-1,3-oxazole-4-carboxamide
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C32H38N6O4
 2
1
EC50 < 100 nM
   TI
   LI
   LO
   TS
2
EC50 = 99000 nM
   TI
   LI
   LO
   TS
CP0452363
N-[2-[4-(2-methylphenyl)piperazin-1-yl]-5-[3-(2-oxopyrrolidin-1-yl)propylcarbamoyl]phenyl]furan-2-carboxamide
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C30H35N5O4
 1
1
EC50 < 100 nM
   TI
   LI
   LO
   TS
CP0561948
2-cyclopropyl-N-[5-[[(1S,3S)-3-hydroxycyclohexyl]carbamoyl]-2-[4-(2-methylphenyl)piperazin-1-yl]phenyl]-1,3-oxazole-4-carboxamide
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C31H37N5O4
 1
1
EC50 < 100 nM
   TI
   LI
   LO
   TS
CP0481365
N-[2-[4-(2-methylphenyl)piperazin-1-yl]-5-[3-(2-oxo-1,3-oxazolidin-3-yl)propylcarbamoyl]phenyl]furan-2-carboxamide
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C29H33N5O5
 1
1
EC50 = 28000 nM
   TI
   LI
   LO
   TS
CP0559018
N-[2-[4-(2-methylphenyl)piperazin-1-yl]-5-[2-(2-oxopyrrolidin-1-yl)ethylcarbamoyl]phenyl]furan-2-carboxamide
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C29H33N5O4
 1
1
EC50 = 30000 nM
   TI
   LI
   LO
   TS
CP0391442
N-[5-[(3-carbamoylphenyl)methylcarbamoyl]-2-[4-(2-methylphenyl)piperazin-1-yl]phenyl]furan-2-carboxamide
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C31H31N5O4
 1
1
EC50 = 46000 nM
   TI
   LI
   LO
   TS
CP0559019
2-cyclopropyl-N-[5-[[(1R,2S,3R)-2,3-dihydroxycyclohexyl]carbamoyl]-2-[4-(2-methylphenyl)piperazin-1-yl]phenyl]-1,3-oxazole-4-carboxamide
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C31H37N5O5
 1
1
EC50 = 53000 nM
   TI
   LI
   LO
   TS
CP0412745
N-[2-[4-(2-methylphenyl)piperazin-1-yl]-5-[3-(oxolan-3-yl)propylcarbamoyl]phenyl]furan-2-carboxamide
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C30H36N4O4
 1
1
EC50 = 88000 nM
   TI
   LI
   LO
   TS