| Compound ID |
Compound Name |
Compound Formula |
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CP0404225
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-methylpyridin-2-yl)benzamide
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C29H24ClN5O3
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2
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| 1 |
IC50 = 1 nM
|
|
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| 2 |
IC50 = 170 nM
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CP0450807
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-methoxypyrimidin-2-yl)benzamide
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C28H23ClN6O4
|
2
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| 1 |
IC50 = 3 nM
|
|
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| 2 |
IC50 = 520 nM
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CP0323280
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2-chloro-4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-methylpyridin-2-yl)benzamide
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|
C29H23Cl2N5O3
|
1
|
| 1 |
IC50 = 24 nM
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|
|
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CP0517646
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-methoxypyrimidin-2-yl)-2-methylbenzamide
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|
C29H25ClN6O4
|
1
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| 1 |
IC50 = 29 nM
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|
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CP0536850
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-methoxypyridin-2-yl)benzamide
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|
C29H24ClN5O4
|
1
|
| 1 |
IC50 = 43 nM
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|
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CP0424464
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2-chloro-4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-cyanopyridin-2-yl)benzamide
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C29H20Cl2N6O3
|
1
|
| 1 |
IC50 = 52 nM
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|
|
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CP0436015
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2-chloro-4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-methoxypyrimidin-2-yl)benzamide
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|
C28H22Cl2N6O4
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1
|
| 1 |
IC50 = 53 nM
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|
|
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CP0334651
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2-chloro-4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-methoxypyridin-2-yl)benzamide
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C29H23Cl2N5O4
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1
|
| 1 |
IC50 = 61 nM
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|
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CP0366069
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-2-methyl-N-(5-methylpyridin-2-yl)benzamide
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|
C30H26ClN5O3
|
1
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| 1 |
IC50 = 61 nM
|
|
|
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CP0558003
|
4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-fluoropyridin-2-yl)-2-methylbenzamide
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|
C29H23ClFN5O3
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
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CP0469329
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-methoxypyridin-2-yl)-2-methylbenzamide
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|
C30H26ClN5O4
|
1
|
| 1 |
IC50 = 71 nM
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|
|
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CP0225381
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-cyanopyridin-2-yl)-2-methylbenzamide
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|
C30H23ClN6O3
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
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CP0160362
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-2-methyl-N-(5-methylpyrimidin-2-yl)benzamide
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|
C29H25ClN6O3
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
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CP0222526
|
2-chloro-4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-methylpyrimidin-2-yl)benzamide
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|
C28H22Cl2N6O3
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
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CP0436014
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2-chloro-4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-fluoropyridin-2-yl)benzamide
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|
C28H20Cl2FN5O3
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
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CP0459069
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-2-methoxy-N-(5-methoxypyridin-2-yl)benzamide
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C30H26ClN5O5
|
1
|
| 1 |
IC50 = 130 nM
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|
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CP0537912
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-2-methyl-N-[5-(trifluoromethyl)pyridin-2-yl]benzamide
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C30H23ClF3N5O3
|
1
|
| 1 |
IC50 = 170 nM
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|
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CP0517639
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2-chloro-4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-methylpyrazin-2-yl)benzamide
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|
C28H22Cl2N6O3
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
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CP0528992
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-pyridin-2-ylbenzamide
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|
C28H22ClN5O3
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
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CP0557317
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2-chloro-4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-[5-(trifluoromethyl)pyridin-2-yl]benzamide
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|
C29H20Cl2F3N5O3
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
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CP0517648
|
(3R)-8-chloro-4-[[4-(1-methylpyrrolo[3,2-b]pyridine-3-carbonyl)phenyl]methyl]-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepine-2,5-dione
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|
C31H24ClN5O3
|
1
|
| 1 |
IC50 = 330 nM
|
|
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CP0467677
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2-chloro-4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-methoxypyrazin-2-yl)benzamide
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|
C28H22Cl2N6O4
|
1
|
| 1 |
IC50 = 490 nM
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|
|
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CP0436013
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(3R)-8-chloro-4-[[4-(imidazo[1,2-a]pyridine-8-carbonyl)phenyl]methyl]-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepine-2,5-dione
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C30H22ClN5O3
|
1
|
| 1 |
IC50 = 660 nM
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CP0436016
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-2-methoxy-N-[5-(trifluoromethyl)pyridin-2-yl]benzamide
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|
C30H23ClF3N5O4
|
1
|
| 1 |
IC50 = 660 nM
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CP0210833
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-fluoropyridin-2-yl)-2-methoxybenzamide
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|
C29H23ClFN5O4
|
1
|
| 1 |
IC50 = 1100 nM
|
|
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CP0147048
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(3R)-8-chloro-3-(pyridin-2-ylmethyl)-4-[[4-([1,2,4]triazolo[1,5-a]pyridine-8-carbonyl)phenyl]methyl]-1,3-dihydro-1,4-benzodiazepine-2,5-dione
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C29H21ClN6O3
|
1
|
| 1 |
IC50 = 1600 nM
|
|
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CP0147046
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(3R)-8-chloro-3-(pyridin-2-ylmethyl)-4-[[4-(1H-pyrrolo[3,2-b]pyridine-3-carbonyl)phenyl]methyl]-1,3-dihydro-1,4-benzodiazepine-2,5-dione
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|
C30H22ClN5O3
|
1
|
| 1 |
IC50 = 1800 nM
|
|
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CP0436012
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-2-methoxy-N-(5-methylpyridin-2-yl)benzamide
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|
C30H26ClN5O4
|
1
|
| 1 |
IC50 = 1900 nM
|
|
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CP0160363
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(3R)-8-chloro-4-[[4-(pyridine-2-carbonyl)phenyl]methyl]-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepine-2,5-dione
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C28H21ClN4O3
|
1
|
| 1 |
IC50 = 4200 nM
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CP0346198
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-3-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-pyridin-2-ylbenzamide
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C28H22ClN5O3
|
1
|
| 1 |
IC50 = 4500 nM
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|
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CP0532436
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(3R)-8-chloro-4-[[4-(5-methylpyridine-2-carbonyl)phenyl]methyl]-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepine-2,5-dione
Show/Hide
|
C29H23ClN4O3
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1
|
| 1 |
IC50 = 5900 nM
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CP0536849
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-3-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-pyrazin-2-ylbenzamide
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C27H21ClN6O3
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1
|
| 1 |
IC50 = 13000 nM
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CP0189045
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-3-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(5-methyl-1,2-oxazol-3-yl)benzamide
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C27H22ClN5O4
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1
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| 1 |
IC50 = 19000 nM
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CP0352461
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4-[[(3R)-8-chloro-2,5-dioxo-3-(pyridin-3-ylmethyl)-1,3-dihydro-1,4-benzodiazepin-4-yl]methyl]-N-(1,3-thiazol-2-yl)benzamide
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C26H20ClN5O3S
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1
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| 1 |
IC50 = 20000 nM
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CP0459070
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(3R)-8-chloro-4-[[4-(1-methylimidazole-4-carbonyl)phenyl]methyl]-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepine-2,5-dione
Show/Hide
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C27H22ClN5O3
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1
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| 1 |
IC50 > 100000 nM
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CP0558033
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(3R)-8-chloro-4-[[4-(1-methylimidazole-2-carbonyl)phenyl]methyl]-3-(pyridin-2-ylmethyl)-1,3-dihydro-1,4-benzodiazepine-2,5-dione
Show/Hide
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C27H22ClN5O3
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1
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| 1 |
IC50 > 100000 nM
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