Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
 Cell Line Info 
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT04126 , Neuromedin-K receptor
 Protein Info 
Gene Name TACR3
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P16177
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011
 Cell Line Info 
 Protein ID: PT04126
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0751077
 Compound Info 
(S)-4-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-4-(oxalyl-amino)-butyric acid
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C39H53N7O11S
  1
1
EC50 = 0.013 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0088817
 Compound Info 
(S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
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C40H55N7O11S
  2
1
EC50 = 0.023 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0402314
 Compound Info 
[(1S)-2-methyl-1-phenylpropyl] N-[(2R)-1-[7-(carbamoylamino)heptylamino]-3-(2,3-difluorophenyl)-2-methyl-1-oxopropan-2-yl]carbamate
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C29H40F2N4O4
  1
1
IC50 = 30 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0373658
 Compound Info 
[(1S)-2-methyl-1-phenylpropyl] N-[(2R)-1-[7-(carbamoylamino)heptylamino]-3-(2-fluorophenyl)-2-methyl-1-oxopropan-2-yl]carbamate
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C29H41FN4O4
  1
1
IC50 = 83 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0409470
 Compound Info 
tert-butyl N-[(2S)-1-[[(2R)-1-[7-(carbamoylamino)heptylamino]-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
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C32H47N5O5
  1
1
IC50 = 1730 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0507580
 Compound Info 
tert-butyl N-[(2S)-1-[[(2R)-1-(8-hydroxyoctylamino)-2-methyl-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
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C32H47N3O5
  1
1
IC50 = 2790 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS