Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
 Cell Line Info 
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT04007 , Melanocortin receptor 4
 Protein Info 
Gene Name MC4R
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P70596
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011
 Cell Line Info 
 Protein ID: PT04007
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0083436
 Compound Info 
N-[(1S)-1-[2-[1-[(3S,4R)-4-(4-bromo-2-fluorophenyl)-1-tert-butylpyrrolidine-3-carbonyl]piperidin-4-yl]-5-chlorophenyl]propyl]acetamide
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C31H40BrClFN3O2
  1
1
EC50 = 0.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0202447
 Compound Info 
N-[(1S)-1-[2-[1-[(3S,4R)-1-tert-butyl-4-(4-chloro-2-fluorophenyl)pyrrolidine-3-carbonyl]piperidin-4-yl]-5-chlorophenyl]propyl]acetamide
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C31H40Cl2FN3O2
  1
1
EC50 = 0.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0283823
 Compound Info 
2-((S)-6-chloro-1'-((3S,4R)-4-(2,4-difluorophenyl)-1-(tetrahydro-2H-pyran-4-yl)pyrrolidine-3-carbonyl)-5-methyl-3H-spiro[isobenzofuran-1,4'-piperidine]-3-yl)-2-methylpropanenitrile
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C33H38ClF2N3O3
  1
1
EC50 = 1.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0162604
 Compound Info 
N-[(1S)-1-[2-[1-[(3R,4S)-4-(4-bromo-2-fluorophenyl)-1-tert-butylpyrrolidine-3-carbonyl]piperidin-4-yl]-5-chlorophenyl]propyl]acetamide
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C31H40BrClFN3O2
  1
1
EC50 = 10.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0149367
 Compound Info 
(R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl-4-[1,2,4]triazol-1-ylmethyl-piperidin-1-yl)-2-oxo-ethyl]-amide
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C33H41ClN6O2
  1
1
IC50 = 0.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0377912
 Compound Info 
(1R,4S,6R)-2-Methyl-2-aza-bicyclo[2.2.2]octane-6-carboxylic acid [(R)-2-(4-tert-butylcarbamoyl-4-cyclohexyl-piperidin-1-yl)-1-(4-fluoro-benzyl)-2-oxo-ethyl]-amide
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C34H51FN4O3
  1
1
IC50 = 3000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS