Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT03581 , Sodium channel protein type 8 subunit alpha
Gene Name SCN8A
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID Q9UQD0
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT03581
 
Compound ID Compound Name Compound Formula
CP0527982
US9546164, 100
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C25H29Cl2FN2O4S
 1
1
IC50 = 198 nM
   TI
   LI
   LO
   TS
CP0116756
US8952169, 64
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C24H31FN2O4S
 1
1
IC50 = 480 nM
   TI
   LI
   LO
   TS
CP0567644
N-[(3aS,4S,9S,10aS)-2,6-diamino-4-[(2,5-dioxopyrrolidin-1-yl)methyl]-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-9-yl]-5,6,7,8-tetrahydronaphthalene-1-carboxamide
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C24H30N8O5
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0472022
(4S)-6-fluoro-4-[(2R,4S)-2-pyridin-2-yl-4-(trifluoromethyl)piperidin-1-yl]-N-pyrimidin-4-yl-3,4-dihydro-2H-chromene-7-sulfonamide
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C24H23F4N5O3S
 1
1
Kd = 29 nM
   TI
   LI
   LO
   TS