Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT03372 , Gamma-aminobutyric acid receptor subunit alpha-2
Gene Name GABRA2
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID P47869
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT03372
 
Compound ID Compound Name Compound Formula
CP0471857
3-(2-chlorobenzyloxy)-2-(2-fluorophenyl)-2H-pyrazolo[4,3-c]quinoline
   Show/Hide
C23H15ClFN3O
 1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CP0806010
2-(4-chlorophenyl)-2H-pyrazolo[4,3-c]quinolin-3(5H)-one
   Show/Hide
C16H10ClN3O
 1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
CP0489251
2-(4-chlorophenyl)-3-(4-fluorobenzyloxy)-6,7,8,9-tetrahydro-2H-pyrazolo[4,3-c]quinoline
   Show/Hide
C23H19ClFN3O
 1
1
IC50 = 57 nM
   TI
   LI
   LO
   TS
CP0381663
2-(4-chlorophenyl)-3-(2-fluorobenzyloxy)-6,7,8,9-tetrahydro-2H-pyrazolo[4,3-c]quinoline
   Show/Hide
C23H19ClFN3O
 1
1
IC50 = 154 nM
   TI
   LI
   LO
   TS
CP0469122
2-(benzo[d][1,3]dioxol-5-yl)-3-(2-chlorobenzyloxy)-2H-pyrazolo[4,3-c]quinoline
   Show/Hide
C24H16ClN3O3
 1
1
IC50 = 155 nM
   TI
   LI
   LO
   TS
CP0381662
3-(4-chlorobenzyloxy)-2-(4-chlorophenyl)-6,7,8,9-tetrahydro-2H-pyrazolo[4,3-c]quinoline
   Show/Hide
C23H19Cl2N3O
 1
1
IC50 = 177 nM
   TI
   LI
   LO
   TS
CP0492329
2-(4-chlorophenyl)-3-(cyclopropylmethoxy)-6,7,8,9-tetrahydro-2H-pyrazolo[4,3-c]quinoline
   Show/Hide
C20H20ClN3O
 1
1
IC50 = 185 nM
   TI
   LI
   LO
   TS
CP0381664
3-(2-chlorobenzyloxy)-2-(4-chlorophenyl)-8,8-dimethyl-6,7,8,9-tetrahydro-2H-pyrazolo[4,3-c]quinoline
   Show/Hide
C25H23Cl2N3O
 1
1
IC50 = 213 nM
   TI
   LI
   LO
   TS
CP0471840
3-(2-chlorobenzyloxy)-2-(4-chlorophenyl)-2H-pyrazolo[4,3-c]quinoline
   Show/Hide
C23H15Cl2N3O
 1
1
IC50 = 265 nM
   TI
   LI
   LO
   TS
CP0502352
3-(2-chlorobenzyloxy)-2-(4-chlorophenyl)-6,7,8,9-tetrahydro-2H-pyrazolo[4,3-c]quinoline
   Show/Hide
C23H19Cl2N3O
 1
1
IC50 = 271 nM
   TI
   LI
   LO
   TS
CP0469121
3-(2-chlorobenzyloxy)-2-(4-chlorophenyl)-2,6,7,9-tetrahydropyrano[4,3-b]pyrazolo[3,4-d]pyridine
   Show/Hide
C22H17Cl2N3O2
 1
1
IC50 = 461 nM
   TI
   LI
   LO
   TS
CP0471858
2-(4-chlorophenyl)-3-(cyclopropylmethoxy)-2H-pyrazolo[4,3-c]quinoline
   Show/Hide
C20H16ClN3O
 1
1
IC50 = 472 nM
   TI
   LI
   LO
   TS
CP0480355
3-(2-chlorobenzyloxy)-2-(4-chlorophenyl)-2,6,7,8,9,10-hexahydrocyclohepta[b]pyrazolo[3,4-d]pyridine
   Show/Hide
C24H21Cl2N3O
 1
1
IC50 = 605 nM
   TI
   LI
   LO
   TS
CP0504403
2-(4-chlorophenyl)-3-(cyclopropylmethoxy)-8-(1H-imidazol-1-yl)-2H-pyrazolo[4,3-c]quinoline
   Show/Hide
C23H18ClN5O
 1
1
IC50 = 2114 nM
   TI
   LI
   LO
   TS
CP0505700
3-(2-chlorophenoxy)-2-(4-chlorophenyl)-6,7,8,9-tetrahydro-2H-pyrazolo[4,3-c]quinoline
   Show/Hide
C22H17Cl2N3O
 1
1
IC50 > 3000 nM
   TI
   LI
   LO
   TS