Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT03022 , Sodium channel protein type 2 subunit alpha
Gene Name SCN2A
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID Q99250
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT03022
 
Compound ID Compound Name Compound Formula
CP0375108
4-butoxy-N-[N'-(4-phenylbutyl)carbamimidoyl]benzamide
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C22H29N3O2
 1
1
IC50 = 630 nM
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CP0444107
4-ethoxy-N-[N'-(4-phenylbutyl)carbamimidoyl]benzamide
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C20H25N3O2
 1
1
IC50 = 760 nM
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CP0453220
4-methoxy-N-[N'-(4-phenylbutyl)carbamimidoyl]benzamide
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C19H23N3O2
 1
1
IC50 = 820 nM
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CP0492729
N-[N'-(4-phenylbutyl)carbamimidoyl]naphthalene-1-carboxamide
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C22H23N3O
 1
1
IC50 = 860 nM
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CP0453181
4-methyl-N-[N'-(4-phenylbutyl)carbamimidoyl]benzamide
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C19H23N3O
 1
1
IC50 = 1140 nM
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CP0453500
2-methyl-N-[N'-(4-phenylbutyl)carbamimidoyl]benzamide
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C19H23N3O
 1
1
IC50 = 1200 nM
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CP0391416
3,4,5-trimethoxy-N-[N'-(4-phenylbutyl)carbamimidoyl]benzamide
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C21H27N3O4
 1
1
IC50 = 1390 nM
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CP0375122
2,3-dichloro-N-[N'-(4-phenylbutyl)carbamimidoyl]benzamide
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C18H19Cl2N3O
 1
1
IC50 = 1480 nM
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CP0430912
N-[N'-[2-(5-methoxy-1H-indol-3-yl)ethyl]carbamimidoyl]-4-methylbenzamide
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C20H22N4O2
 1
1
IC50 = 1760 nM
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CP0508613
4-methyl-N-[N'-(3,4,5-trimethoxyphenyl)carbamimidoyl]benzamide
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C18H21N3O4
 1
1
IC50 = 1920 nM
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CP0430911
4-methyl-N-[N'-(4-propan-2-ylphenyl)carbamimidoyl]benzamide
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C18H21N3O
 1
1
IC50 = 1950 nM
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CP0430923
N-[N'-[2-(4-chlorophenyl)ethyl]carbamimidoyl]-4-methylbenzamide
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C17H18ClN3O
 1
1
IC50 = 1970 nM
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CP0501921
4-methyl-N-[N'-(4-propan-2-yloxyphenyl)carbamimidoyl]benzamide
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C18H21N3O2
 1
1
IC50 = 2020 nM
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CP0348250
US9012443, 261
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C19H13F3N4O3S2
 1
1
IC50 = 2100 nM
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CP0414861
4-methyl-N-[N'-(5-phenylpentyl)carbamimidoyl]benzamide
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C20H25N3O
 1
1
IC50 = 2110 nM
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CP0497887
4-methyl-N-[N'-(naphthalen-1-ylmethyl)carbamimidoyl]benzamide
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C20H19N3O
 1
1
IC50 = 2380 nM
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CP0526927
4-methyl-N-[N'-(2-phenylethyl)carbamimidoyl]benzamide
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C17H19N3O
 1
1
IC50 = 2660 nM
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CP0453499
4-methyl-N-[N'-(3-phenoxypropyl)carbamimidoyl]benzamide
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C18H21N3O2
 1
1
IC50 = 2670 nM
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CP0383545
4-methyl-N-[N'-(2-phenoxyethyl)carbamimidoyl]benzamide
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C17H19N3O2
 1
1
IC50 = 3230 nM
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CP0441744
2,5-dichloro-N-[N'-(4-phenylbutyl)carbamimidoyl]benzamide
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C18H19Cl2N3O
 1
1
IC50 = 3250 nM
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CP0432389
4-methyl-N-(N'-naphthalen-1-ylcarbamimidoyl)benzamide
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C19H17N3O
 1
1
IC50 = 3290 nM
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CP0434432
N-[N'-[2-(4-methoxy-1H-indol-3-yl)ethyl]carbamimidoyl]-4-methylbenzamide
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C20H22N4O2
 1
1
IC50 = 3350 nM
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CP0441906
N-(N'-benzylcarbamimidoyl)-4-methylbenzamide
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C16H17N3O
 1
1
IC50 = 3870 nM
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CP0383088
N-[N'-(2-benzylsulfanylethyl)carbamimidoyl]-4-methylbenzamide
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C18H21N3OS
 1
1
IC50 = 3900 nM
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CP0406161
4-methyl-N-[N'-methyl-N-(4-phenylbutyl)carbamimidoyl]benzamide
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C20H25N3O
 1
1
IC50 = 4160 nM
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CP0440191
4-chloro-N-[N'-(4-phenylbutyl)carbamimidoyl]benzamide
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C18H20ClN3O
 1
1
IC50 = 4300 nM
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CP0437894
N-[N'-(4-phenylbutyl)carbamimidoyl]thiophene-2-carboxamide
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C16H19N3OS
 1
1
IC50 = 4310 nM
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CP0409607
4-methyl-N-[N'-(2-propan-2-ylphenyl)carbamimidoyl]benzamide
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C18H21N3O
 1
1
IC50 = 4360 nM
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CP0430694
4-methyl-N-[N'-(2-thiophen-2-ylethyl)carbamimidoyl]benzamide
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C15H17N3OS
 1
1
IC50 = 4950 nM
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CP0427278
2,6-dichloro-N-[N'-(4-phenylbutyl)carbamimidoyl]benzamide
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C18H19Cl2N3O
 1
1
IC50 = 5030 nM
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CP0408959
N-[amino-[methyl-(3-methylphenyl)sulfanylamino]methylidene]-4-methylbenzamide
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C17H19N3OS
 1
1
IC50 = 5440 nM
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CP0454740
4-methyl-N-[N'-(3-phenylpropyl)carbamimidoyl]benzamide
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C18H21N3O
 1
1
IC50 = 6030 nM
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CP0524330
3,4-dichloro-N-[N'-(4-phenylbutyl)carbamimidoyl]benzamide
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C18H19Cl2N3O
 1
1
IC50 = 7110 nM
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CP0381028
N-(2,3-dihydroindole-1-carboximidoyl)-4-methylbenzamide
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C17H17N3O
 1
1
IC50 = 8810 nM
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CP0375403
N-[amino-(3-iodo-N-methylanilino)methylidene]-4-methylbenzamide
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C16H16IN3O
 1
1
IC50 = 9450 nM
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CP0421283
4-(5-Chloro-6-((1-Methylcyclopropyl)Methoxy)Pyridin-3-yl)-2-Fluoro-5-Methoxy-N-(Methylsulfonyl)Benzamide
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C20H14ClF3N2O5S
 1
1
IC50 = 9800 nM
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CP0391342
4-methyl-N-[N'-(4-phenylmethoxyphenyl)carbamimidoyl]benzamide
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C22H21N3O2
 1
1
IC50 = 10090 nM
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CP0448195
N-[N'-(4-phenylbutyl)carbamimidoyl]furan-2-carboxamide
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C16H19N3O2
 1
1
IC50 = 13750 nM
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CP0381027
N-(N'-butylcarbamimidoyl)-4-methylbenzamide
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C13H19N3O
 1
1
IC50 = 17350 nM
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CP0462840
N-[N'-(4-tert-butylphenyl)carbamimidoyl]-4-methylbenzamide
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C19H23N3O
 1
1
IC50 > 24000 nM
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CP0432408
4-methyl-N-[7-(trifluoromethyl)-3,4-dihydro-2H-quinoline-1-carboximidoyl]benzamide
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C19H18F3N3O
 1
1
IC50 > 25000 nM
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CP0464594
N-[N'-(2,5-dibromophenyl)carbamimidoyl]-4-methylbenzamide
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C15H13Br2N3O
 1
1
IC50 > 25000 nM
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CP0502445
N-[N'-[3-(dimethylamino)propyl]carbamimidoyl]-4-methylbenzamide
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C14H22N4O
 1
1
IC50 > 25000 nM
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CP0567644
N-[(3aS,4S,9S,10aS)-2,6-diamino-4-[(2,5-dioxopyrrolidin-1-yl)methyl]-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-9-yl]-5,6,7,8-tetrahydronaphthalene-1-carboxamide
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C24H30N8O5
 1
1
IC50 > 100000 nM
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