| Compound ID |
Compound Name |
Compound Formula |
|
CP0374208
|
1-(4-(3-cyclopropyl-5-(trifluoromethyl)phenylsulfonyl)piperazin-1-yl)-2-(4-(trifluoromethyl)phenyl)ethanone
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|
C23H22F6N2O3S
|
4
|
| 1 |
EC50 = 0.6 nM
|
|
|
| 2 |
IC50 = 1.9 nM
|
|
|
| 3 |
IC50 = 11 nM
|
|
|
| 4 |
IC50 = 27 nM
|
|
|
|
CP0424908
|
(4-(3-cyclopropyl-5-(trifluoromethyl)phenylsulfonyl)piperazin-1-yl)((1R,2R)-2-(4-(trifluoromethyl)phenyl)cyclopropyl)methanone
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|
C25H24F6N2O3S
|
4
|
| 1 |
EC50 = 3.4 nM
|
|
|
| 2 |
IC50 = 0.2 nM
|
|
|
| 3 |
IC50 = 2.2 nM
|
|
|
| 4 |
IC50 = 9.2 nM
|
|
|
|
CP0384460
|
(4-(3-cyclopropyl-5-(trifluoromethyl)phenylsulfonyl)piperazin-1-yl)(4-(trifluoromethyl)phenyl)methanone
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|
C22H20F6N2O3S
|
4
|
| 1 |
EC50 = 4.4 nM
|
|
|
| 2 |
IC50 = 77 nM
|
|
|
| 3 |
IC50 = 175 nM
|
|
|
| 4 |
IC50 = 227 nM
|
|
|
|
CP0400699
|
N-propyl-2-(tricyclo[3.3.1.03,7]nonane-3-carbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
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|
C22H30N2O2S
|
1
|
| 1 |
Ki = 46.77 nM
|
|
|
|
CP0400705
|
N-[3-(3,3-difluoroazetidine-1-carbonyl)-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl]tricyclo[3.3.1.03,7]nonane-3-carboxamide
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|
C21H24F2N2O3S
|
1
|
| 1 |
Ki = 66.07 nM
|
|
|
|
CP0410344
|
N-propyl-2-[(2,2,3,3-tetramethylcyclopropanecarbonyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide
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|
C19H28N2O3S
|
1
|
| 1 |
Ki = 190.55 nM
|
|
|
|
CP0400698
|
N-propyl-2-(tricyclo[3.3.1.03,7]nonane-3-carbonylamino)-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide
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|
C21H28N2O3S
|
1
|
| 1 |
Ki = 302 nM
|
|
|
|
CP0410345
|
2-(adamantane-1-carbonylamino)-N-propyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxamide
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|
C22H30N2O3S
|
1
|
| 1 |
Ki = 524.81 nM
|
|
|
|
CP0434911
|
N-[3-(morpholine-4-carbonyl)-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl]tricyclo[3.3.1.03,7]nonane-3-carboxamide
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|
C22H28N2O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
