| Compound ID |
Compound Name |
Compound Formula |
|
CP0503446
|
2-((S)-6-amino-2-((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)hexanamido)acetic acid
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|
C47H66N10O12S2
|
2
|
| 1 |
EC50 = 1.5 nM
|
|
|
| 2 |
Ki = 0.52 nM
|
|
|
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CP0479071
|
2-((S)-2-((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-6-(2-aminobenzamido)hexanamido)acetic acid
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|
C54H71N11O13S2
|
3
|
| 1 |
EC50 = 1.7 nM
|
|
|
| 2 |
EC50 = 2.48 nM
|
|
|
| 3 |
Ki = 0.65 nM
|
|
|
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CP0192572
|
AVP
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|
C46H65N15O12S2
|
3
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
Ki = 0.49 nM
|
|
|
| 3 |
Ki = 0.68 nM
|
|
|
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CP0881072
|
triethylamine hemi(2-((S)-2-((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-6-(2-(6-amino-3-imino-4,5-disulfonato-3H-xanthen-9-yl)-5-((2,3,5,6-tetrafluorophenoxy)carbonyl)benzamido)hexanamido)acetate)
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|
C68H76Li2N12O22S4
|
2
|
| 1 |
EC50 = 6.93 nM
|
|
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| 2 |
Ki = 1.2 nM
|
|
|
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CP0117986
|
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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|
C43H66N12O12S2
|
2
|
| 1 |
EC50 = 24.5 nM
|
|
|
| 2 |
EC50 = 33 nM
|
|
|
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CP0476263
|
(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-2,21-dithia-5,8,11,14,17-pentazabicyclo[21.2.2]heptacosa-1(25),23,26-triene-4-carbonyl]pyrrolidine-2-carboxamide
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|
C50H71N11O12S2
|
1
|
| 1 |
EC50 = 2223 nM
|
|
|
|
CP0387328
|
(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(5R,8S,11S,14S,17S)-8-(2-amino-2-oxoethyl)-11-(3-amino-3-oxopropyl)-14-[(2S)-butan-2-yl]-17-[(4-hydroxyphenyl)methyl]-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carbonyl]pyrrolidine-2-carboxamide
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|
C51H73N11O12S2
|
1
|
| 1 |
EC50 = 2966 nM
|
|
|
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CP0386760
|
(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(5R,8S,11S,14S,17S)-8-(2-amino-2-oxoethyl)-11-(3-amino-3-oxopropyl)-14-[(2S)-butan-2-yl]-17-[(4-hydroxyphenyl)methyl]-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carbonyl]pyrrolidine-2-carboxamide
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|
C51H73N11O12S2
|
1
|
| 1 |
EC50 = 8302 nM
|
|
|
|
CP0430562
|
(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(5R,8S,11S,14S,17S)-8-(2-amino-2-oxoethyl)-11-(3-amino-3-oxopropyl)-14-[(2S)-butan-2-yl]-17-[(4-hydroxyphenyl)methyl]-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carbonyl]pyrrolidine-2-carboxamide
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|
C51H74N14O12S2
|
1
|
| 1 |
EC50 = 9263 nM
|
|
|
|
CP0399786
|
2-(6-(3-((dimethylamino)methyl)phenyl)-2-(4-fluoro-3-methoxyphenyl)-4-oxoquinazolin-3(4H)-yl)-N-isopropylacetamide
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|
C29H31FN4O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0512468
|
2-[2-(3-methoxyphenyl)-4-oxo-6-[3-(piperidin-1-ylmethyl)phenyl]quinazolin-3-yl]-N-propan-2-ylacetamide
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|
C32H36N4O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0545316
|
N-tert-butyl-2-[3-(3-chlorophenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]acetamide
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|
C27H35ClN4O3
|
1
|
| 1 |
IC50 = 2.512 nM
|
|
|
|
CP0140566
|
2-[2-(3-methoxyphenyl)-4-oxo-6-(3-piperidin-1-ylpropoxy)quinazolin-3-yl]-N-propan-2-ylacetamide
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|
C28H36N4O4
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0470863
|
2-[6-[4-fluoro-3-(trifluoromethyl)phenyl]-4-oxo-2-(3-piperidin-1-ylpropoxy)pyrazolo[1,5-a]pyrazin-5-yl]-N-propan-2-ylacetamide
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|
C26H31F4N5O3
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0507806
|
2-[3-(3-chloro-4-fluorophenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
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|
C26H32ClFN4O3
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0489223
|
2-[2-(3-methoxyphenyl)-6-(3-morpholin-4-ylpropoxy)-4-oxoquinazolin-3-yl]-N-propan-2-ylacetamide
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|
C27H34N4O5
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0404971
|
2-(2-(3-chlorophenyl)-6-(3-morpholinopropoxy)-4-oxoquinazolin-3(4H)-yl)-N-isopropylacetamide
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|
C26H31ClN4O4
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0489502
|
2-[3-(3-chlorophenyl)-7-(1-cyclopentylpiperidin-4-yl)oxy-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
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|
C28H35ClN4O3
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0513595
|
2-[3-[4-fluoro-3-(trifluoromethyl)phenyl]-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
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|
C27H32F4N4O3
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0523864
|
2-[3-(3-chlorophenyl)-1-oxo-7-(4-piperidin-1-ylpiperidin-1-yl)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
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|
C28H36ClN5O2
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0534636
|
2-[6-(3-chloro-4-fluorophenyl)-4-oxo-2-(3-piperidin-1-ylpropoxy)pyrazolo[1,5-a]pyrazin-5-yl]-N-propan-2-ylacetamide
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|
C25H31ClFN5O3
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0103104
|
2-(2-(3-chlorophenyl)-4-oxo-6-(3-(piperidin-1-yl)propoxy)quinazolin-3(4H)-yl)-N-isopropylacetamide
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|
C27H33ClN4O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0487818
|
2-[3-(3-chlorophenyl)-1-oxo-7-[3-[4-(trifluoromethyl)piperidin-1-yl]propoxy]pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
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|
C27H32ClF3N4O3
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0502135
|
2-[3-(3-chlorophenyl)-1-oxo-7-[3-[3-(trifluoromethyl)pyrrolidin-1-yl]propoxy]pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
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|
C26H30ClF3N4O3
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0514185
|
2-[3-(3-chlorophenyl)-1-oxo-7-(4-pyrrolidin-1-ylpiperidin-1-yl)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
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|
C27H34ClN5O2
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0504629
|
2-(6-(5-((dimethylamino)methyl)-2-fluorophenyl)-2-(3-methoxyphenyl)-4-oxoquinazolin-3(4H)-yl)-N-isopropylacetamide
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|
C29H31FN4O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0371943
|
2-(2-(3-chlorophenyl)-4-oxo-6-(3-(piperidin-1-ylmethyl)phenyl)quinazolin-3(4H)-yl)-N-isopropylacetamide
Show/Hide
|
C31H33ClN4O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0464992
|
2-(6-(3-((dimethylamino)methyl)phenyl)-2-(3-methoxyphenyl)-4-oxoquinazolin-3(4H)-yl)-N-isopropylacetamide
Show/Hide
|
C29H32N4O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0470866
|
2-[3-(3-chlorophenyl)-7-[3-(3-fluoropiperidin-1-yl)propoxy]-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
|
C26H32ClFN4O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0520973
|
2-[3-(3-chlorophenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
|
C26H33ClN4O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0411878
|
2-[3-(3-chlorophenyl)-7-(4-methyl-1,4-diazepan-1-yl)-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
|
C24H30ClN5O2
|
1
|
| 1 |
IC50 = 12.59 nM
|
|
|
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CP0487812
|
2-[3-(3-methoxyphenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
|
C27H36N4O4
|
1
|
| 1 |
IC50 = 12.59 nM
|
|
|
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CP0503542
|
N-(cyclopropylmethyl)-2-[2-(3-methoxyphenyl)-6-(3-morpholin-4-ylpropoxy)-4-oxoquinazolin-3-yl]acetamide
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|
C28H34N4O5
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0489495
|
2-[6-(3-chlorophenyl)-4-oxo-2-(3-piperidin-1-ylpropoxy)pyrazolo[1,5-a]pyrazin-5-yl]-N-propan-2-ylacetamide
Show/Hide
|
C25H32ClN5O3
|
1
|
| 1 |
IC50 = 15.85 nM
|
|
|
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CP0523866
|
2-[6-(3-methoxyphenyl)-4-oxo-2-(3-piperidin-1-ylpropoxy)pyrazolo[1,5-a]pyrazin-5-yl]-N-propan-2-ylacetamide
Show/Hide
|
C26H35N5O4
|
1
|
| 1 |
IC50 = 15.85 nM
|
|
|
|
CP0498912
|
N-cyclopropyl-2-[2-(3-methoxyphenyl)-4-oxo-6-(3-piperidin-1-ylpropoxy)quinazolin-3-yl]acetamide
Show/Hide
|
C28H34N4O4
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0524452
|
2-(2-(3-chlorophenyl)-6-(3-((dimethylamino)methyl)phenyl)-4-oxoquinazolin-3(4H)-yl)-N-isopropylacetamide
Show/Hide
|
C28H29ClN4O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0505591
|
2-(2-(3-chlorophenyl)-6-(3-morpholinopropoxy)-4-oxoquinazolin-3(4H)-yl)-N-cyclopropylacetamide
Show/Hide
|
C26H29ClN4O4
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0404968
|
2-(2-(3-chlorophenyl)-6-(3-morpholinopropoxy)-4-oxoquinazolin-3(4H)-yl)-N-(cyclopropylmethyl)acetamide
Show/Hide
|
C27H31ClN4O4
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0424694
|
N-cyclopropyl-2-[2-(3-methoxyphenyl)-6-(3-morpholin-4-ylpropoxy)-4-oxoquinazolin-3-yl]acetamide
Show/Hide
|
C27H32N4O5
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0555640
|
2-(6-(6-((dimethylamino)methyl)pyridin-2-yl)-2-(3-methoxyphenyl)-4-oxoquinazolin-3(4H)-yl)-N-isopropylacetamide
Show/Hide
|
C28H31N5O3
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0504498
|
2-(2-(3-methoxyphenyl)-6-(3-morpholinopropoxy)-4-oxoquinazolin-3(4H)-yl)-N-propylacetamide
Show/Hide
|
C27H34N4O5
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0509362
|
2-(2-(3-chlorophenyl)-4-oxo-6-(3-(piperidin-1-yl)propoxy)quinazolin-3(4H)-yl)-N-cyclopropylacetamide
Show/Hide
|
C27H31ClN4O3
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0501579
|
2-(6-(3-(azetidin-1-ylmethyl)phenyl)-2-(3-methoxyphenyl)-4-oxoquinazolin-3(4H)-yl)-N-isopropylacetamide
Show/Hide
|
C30H32N4O3
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0438297
|
2-(2-(3-chlorophenyl)-4-oxo-6-(3-(piperidin-1-yl)propoxy)quinazolin-3(4H)-yl)-N-propylacetamide
Show/Hide
|
C27H33ClN4O3
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0514186
|
2-[3-(3-chlorophenyl)-7-[methyl-(1-methylpiperidin-4-yl)amino]-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
|
C25H32ClN5O2
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
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CP0524454
|
2-(6-(4-((dimethylamino)methyl)pyridin-2-yl)-2-(3-methoxyphenyl)-4-oxoquinazolin-3(4H)-yl)-N-isopropylacetamide
Show/Hide
|
C28H31N5O3
|
1
|
| 1 |
IC50 = 52 nM
|
|
|
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CP0487290
|
2-(2-(3-chlorophenyl)-6-(3-morpholinopropoxy)-4-oxoquinazolin-3(4H)-yl)-N-propylacetamide
Show/Hide
|
C26H31ClN4O4
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
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CP0501563
|
N-(cyclopropylmethyl)-2-[4-oxo-2-phenyl-6-[3-(piperidin-1-ylmethyl)phenyl]quinazolin-3-yl]acetamide
Show/Hide
|
C32H34N4O2
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
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CP0524453
|
2-(6-(3-(azetidin-1-ylmethyl)phenyl)-2-(3-chlorophenyl)-4-oxoquinazolin-3(4H)-yl)-N-isopropylacetamide
Show/Hide
|
C29H29ClN4O2
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
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CP0406088
|
2-[3-(3-chlorophenyl)-7-[4-(dimethylamino)piperidin-1-yl]-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
|
C25H32ClN5O2
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
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CP0487815
|
2-[3-(3-chlorophenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]-N-cyclobutylacetamide
Show/Hide
|
C27H33ClN4O3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
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CP0507633
|
2-[3-(3-chlorophenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]-N-(cyclopropylmethyl)acetamide
Show/Hide
|
C27H33ClN4O3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
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CP0519164
|
2-[3-(3-chlorophenyl)-7-(1-methylpiperidin-4-yl)oxy-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
|
C24H29ClN4O3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
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CP0522730
|
2-[3-(3-chlorophenyl)-1-oxo-7-(1-propan-2-ylpiperidin-4-yl)oxypyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
|
C26H33ClN4O3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
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CP0523862
|
2-[7-[3-[(8aS)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]propoxy]-3-(3-chlorophenyl)-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
|
C28H36ClN5O3
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
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CP0487292
|
2-(2-(3-methoxyphenyl)-4-oxo-6-(3-(piperidin-1-yl)propoxy)quinazolin-3(4H)-yl)-N-propylacetamide
Show/Hide
|
C28H36N4O4
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0511776
|
2-(6-(5-((dimethylamino)methyl)pyridin-3-yl)-2-(3-methoxyphenyl)-4-oxoquinazolin-3(4H)-yl)-N-isopropylacetamide
Show/Hide
|
C28H31N5O3
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0524495
|
N-(cyclopropylmethyl)-2-[6-[3-(morpholin-4-ylmethyl)phenyl]-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
|
C31H32N4O3
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0470862
|
2-[3-(5-chloro-2-methylphenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
|
C27H35ClN4O3
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0519160
|
2-[3-(3-fluorophenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
|
C26H33FN4O3
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
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CP0489222
|
N-ethyl-2-[2-(3-methoxyphenyl)-6-(3-morpholin-4-ylpropoxy)-4-oxoquinazolin-3-yl]acetamide
Show/Hide
|
C26H32N4O5
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0487813
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2-[3-(5-chloro-2-fluorophenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
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C26H32ClFN4O3
|
1
|
| 1 |
IC50 = 100 nM
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CP0498907
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N-(cyclopropylmethyl)-2-[2-(3-fluorophenyl)-6-(3-morpholin-4-ylpropoxy)-4-oxoquinazolin-3-yl]acetamide
Show/Hide
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C27H31FN4O4
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1
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| 1 |
IC50 = 113 nM
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CP0228511
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N-(cyclopropylmethyl)-2-[6-(3-morpholin-4-ylpropoxy)-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
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C27H32N4O4
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1
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| 1 |
IC50 = 120 nM
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CP0502778
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2-(2-(3-chlorophenyl)-6-(3-morpholinopropoxy)-4-oxoquinazolin-3(4H)-yl)-N-ethylacetamide
Show/Hide
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C25H29ClN4O4
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1
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| 1 |
IC50 = 122 nM
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CP0543419
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N-(cyclopropylmethyl)-2-[2-(3-methylphenyl)-6-(3-morpholin-4-ylpropoxy)-4-oxoquinazolin-3-yl]acetamide
Show/Hide
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C28H34N4O4
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1
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| 1 |
IC50 = 125 nM
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CP0514187
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2-[3-(3-chlorophenyl)-7-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
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C26H32ClN5O2
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1
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| 1 |
IC50 = 125.89 nM
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CP0542899
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N-ethyl-2-[2-(3-methoxyphenyl)-4-oxo-6-(3-piperidin-1-ylpropoxy)quinazolin-3-yl]acetamide
Show/Hide
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C27H34N4O4
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1
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| 1 |
IC50 = 152 nM
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CP0406084
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2-[6-(3-chloro-2-fluorophenyl)-4-oxo-2-(3-piperidin-1-ylpropoxy)pyrazolo[1,5-a]pyrazin-5-yl]-N-propan-2-ylacetamide
Show/Hide
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C25H31ClFN5O3
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1
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| 1 |
IC50 = 158.49 nM
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CP0498691
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2-(6-(3-(azetidin-1-ylmethyl)phenyl)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-tert-butylacetamide
Show/Hide
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C30H32N4O2
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1
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| 1 |
IC50 = 187 nM
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CP0543422
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2-(2-(3-chlorophenyl)-4-oxo-6-(3-(piperidin-1-yl)propoxy)quinazolin-3(4H)-yl)-N-ethylacetamide
Show/Hide
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C26H31ClN4O3
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1
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| 1 |
IC50 = 196 nM
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CP0415321
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2-[3-(3-chlorophenyl)-1-oxo-7-piperidin-4-yloxypyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
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C23H27ClN4O3
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1
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| 1 |
IC50 = 199.53 nM
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CP0493138
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N-cyclopropyl-2-[3-(3-methoxyphenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]acetamide
Show/Hide
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C27H34N4O4
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1
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| 1 |
IC50 = 199.53 nM
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CP0523863
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2-[7-[3-[(8aR)-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl]propoxy]-3-(3-chlorophenyl)-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
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C28H36ClN5O3
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1
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| 1 |
IC50 = 199.53 nM
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CP0523865
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2-[3-(3-chlorophenyl)-7-(2-methyl-2,8-diazaspiro[4.5]decan-8-yl)-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
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C27H34ClN5O2
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1
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| 1 |
IC50 = 199.53 nM
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CP0470790
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(S)-2-amino-N-((S)-1-(3-(2-(cyclopropylmethylamino)-2-oxoethyl)-4-oxo-2-phenyl-3,4-dihydroquinazolin-6-yloxy)-4-methylpentan-2-yl)-3-(4-hydroxyphenyl)propanamide
Show/Hide
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C35H41N5O5
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1
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| 1 |
IC50 = 200 nM
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CP0371940
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2-(6-(3-(azetidin-1-ylmethyl)phenyl)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-cyclopentylacetamide
Show/Hide
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C31H32N4O2
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1
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| 1 |
IC50 = 238 nM
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CP0469073
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N-(cyclopropylmethyl)-2-[2-(4-fluorophenyl)-6-(3-morpholin-4-ylpropoxy)-4-oxoquinazolin-3-yl]acetamide
Show/Hide
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C27H31FN4O4
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1
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| 1 |
IC50 = 250 nM
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CP0514184
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2-[3-(3-chlorophenyl)-7-(4-methylpiperazin-1-yl)-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
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C23H28ClN5O2
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1
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| 1 |
IC50 = 251.19 nM
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CP0512467
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2-(6-(3-(azetidin-1-ylmethyl)phenyl)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-(cyclopropylmethyl)acetamide
Show/Hide
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C30H30N4O2
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1
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| 1 |
IC50 = 275 nM
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CP0473795
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N-(cyclopropylmethyl)-2-[4-oxo-2-phenyl-6-(3-piperidin-1-ylpropoxy)quinazolin-3-yl]acetamide
Show/Hide
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C28H34N4O3
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1
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| 1 |
IC50 = 310 nM
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CP0438201
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N-(cyclopropylmethyl)-2-[6-[3-[(dimethylamino)methyl]phenyl]-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
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C29H30N4O2
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1
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| 1 |
IC50 = 314 nM
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CP0514177
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2-[6-(3-chlorophenyl)-4-oxo-2-(2-piperidin-1-ylethoxy)pyrazolo[1,5-a]pyrazin-5-yl]-N-propan-2-ylacetamide
Show/Hide
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C24H30ClN5O3
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1
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| 1 |
IC50 = 316.23 nM
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CP0524451
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N-(cyclopropylmethyl)-2-[6-[3-(methylaminomethyl)phenyl]-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
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C28H28N4O2
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1
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| 1 |
IC50 = 320 nM
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CP0487289
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2-(2-(3-methoxyphenyl)-6-(3-morpholinopropoxy)-4-oxoquinazolin-3(4H)-yl)-N-methylacetamide
Show/Hide
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C25H30N4O5
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1
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| 1 |
IC50 = 325 nM
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CP0513064
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N-(cyclopropylmethyl)-2-[6-(3-morpholin-4-ylpropoxy)-4-oxo-2-thiophen-2-ylquinazolin-3-yl]acetamide
Show/Hide
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C25H30N4O4S
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1
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| 1 |
IC50 = 328 nM
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CP0470791
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2-(6-(3-(azepan-1-yl)propoxy)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-(cyclopropylmethyl)acetamide
Show/Hide
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C29H36N4O3
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1
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| 1 |
IC50 = 340 nM
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CP0542898
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N-(cyclopropylmethyl)-2-[2-(2-methylphenyl)-6-(3-morpholin-4-ylpropoxy)-4-oxoquinazolin-3-yl]acetamide
Show/Hide
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C28H34N4O4
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1
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| 1 |
IC50 = 366 nM
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CP0441841
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(1,4-diazepan-1-yl)(5-methoxy-1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2-methyl-1H-indol-3-yl)methanone
Show/Hide
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C25H31N3O5S
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2
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| 1 |
IC50 = 371 nM
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| 2 |
Ki = 190 nM
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CP0404982
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2-(2-(1H-indol-3-yl)-6-(3-morpholinopropoxy)-4-oxoquinazolin-3(4H)-yl)-N-(cyclopropylmethyl)acetamide
Show/Hide
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C29H33N5O4
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1
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| 1 |
IC50 = 387 nM
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CP0475452
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N-(cyclopropylmethyl)-2-[4-oxo-2-phenyl-6-[3-(pyrrolidin-1-ylmethyl)phenyl]quinazolin-3-yl]acetamide
Show/Hide
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C31H32N4O2
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1
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| 1 |
IC50 = 388 nM
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CP0511775
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2-(6-(3-(azetidin-1-ylmethyl)phenyl)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-isopropylacetamide
Show/Hide
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C29H30N4O2
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1
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| 1 |
IC50 = 397 nM
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CP0502134
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2-[3-(3-methoxyphenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide
Show/Hide
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C26H31F3N4O4
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1
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| 1 |
IC50 = 398.11 nM
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CP0514864
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2-[4-oxo-2-(3-piperidin-1-ylpropoxy)-6-[3-(trifluoromethoxy)phenyl]pyrazolo[1,5-a]pyrazin-5-yl]-N-propan-2-ylacetamide
Show/Hide
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C26H32F3N5O4
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1
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| 1 |
IC50 = 398.11 nM
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CP0543421
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N-(cyclopropylmethyl)-2-[6-(3-morpholin-4-ylpropoxy)-4-oxo-2-thiophen-3-ylquinazolin-3-yl]acetamide
Show/Hide
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C25H30N4O4S
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1
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| 1 |
IC50 = 470 nM
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CP0475453
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2-(6-(5-((dimethylamino)methyl)thiophen-2-yl)-2-(3-methoxyphenyl)-4-oxoquinazolin-3(4H)-yl)-N-isopropylacetamide
Show/Hide
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C27H30N4O3S
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1
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| 1 |
IC50 = 500 nM
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CP0377160
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2-[3-(3-chlorophenyl)-7-[3-(dimethylamino)pyrrolidin-1-yl]-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
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C24H30ClN5O2
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1
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| 1 |
IC50 = 501.19 nM
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CP0399300
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2-[3-(3-chlorophenyl)-7-[(1-methylpiperidin-3-yl)methoxy]-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
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C25H31ClN4O3
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1
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| 1 |
IC50 = 501.19 nM
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CP0522731
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2-[3-(3-chlorophenyl)-7-(1-methyl-1,7-diazaspiro[4.4]nonan-7-yl)-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
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C26H32ClN5O2
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1
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| 1 |
IC50 = 501.19 nM
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CP0475451
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N-(cyclopropylmethyl)-2-[6-[3-(diethylaminomethyl)phenyl]-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
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C31H34N4O2
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1
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| 1 |
IC50 = 540 nM
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CP0504628
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2-(6-(3-(azetidin-1-ylmethyl)phenyl)-2-(2-methoxyphenyl)-4-oxoquinazolin-3(4H)-yl)-N-isopropylacetamide
Show/Hide
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C30H32N4O3
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1
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| 1 |
IC50 = 610 nM
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CP0477608
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2-[3-(3-chlorophenyl)-7-(2,7-diazaspiro[3.5]nonan-7-yl)-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
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C25H30ClN5O2
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1
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| 1 |
IC50 = 630.96 nM
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CP0534642
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2-[3-(3-chlorophenyl)-7-[2-(1-methylpiperidin-2-yl)ethoxy]-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
|
C26H33ClN4O3
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1
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| 1 |
IC50 = 630.96 nM
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CP0566060
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N-(cyclopropylmethyl)-2-[6-[3-[(2-methoxyethylamino)methyl]phenyl]-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
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C30H32N4O3
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1
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| 1 |
IC50 = 642 nM
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CP0487288
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N-(cyclopropylmethyl)-2-[2-(furan-3-yl)-6-(3-morpholin-4-ylpropoxy)-4-oxoquinazolin-3-yl]acetamide
Show/Hide
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C25H30N4O5
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1
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| 1 |
IC50 = 644 nM
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CP0505687
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2-(6-(5-((dimethylamino)methyl)furan-2-yl)-2-(3-methoxyphenyl)-4-oxoquinazolin-3(4H)-yl)-N-isopropylacetamide
Show/Hide
|
C27H30N4O4
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1
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| 1 |
IC50 = 700 nM
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CP0541532
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N-(cyclopropylmethyl)-2-[6-[3-(4-methoxypiperidin-1-yl)propoxy]-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
|
C29H36N4O4
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1
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| 1 |
IC50 = 710 nM
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CP0487816
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N-ethyl-2-[3-(3-methoxyphenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]acetamide
Show/Hide
|
C26H34N4O4
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1
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| 1 |
IC50 = 794.33 nM
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CP0489496
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2-[3-(2-chlorophenyl)-1-oxo-7-(3-piperidin-1-ylpropoxy)pyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
|
C26H33ClN4O3
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1
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| 1 |
IC50 = 794.33 nM
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CP0426332
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2-(2-(4-chlorophenyl)-6-(3-morpholinopropoxy)-4-oxoquinazolin-3(4H)-yl)-N-(cyclopropylmethyl)acetamide
Show/Hide
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C27H31ClN4O4
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1
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| 1 |
IC50 = 800 nM
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CP0522727
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2-[6-(3-chlorophenyl)-4-oxo-2-(4-piperidin-1-ylbutoxy)pyrazolo[1,5-a]pyrazin-5-yl]-N-propan-2-ylacetamide
Show/Hide
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C26H34ClN5O3
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1
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| 1 |
IC50 = 1000 nM
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CP0487287
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N-(cyclopropylmethyl)-2-[2-(4-methoxyphenyl)-6-(3-morpholin-4-ylpropoxy)-4-oxoquinazolin-3-yl]acetamide
Show/Hide
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C28H34N4O5
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1
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| 1 |
IC50 = 1030 nM
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CP0504627
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2-(6-(3-(azetidin-1-ylmethyl)phenyl)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-isobutylacetamide
Show/Hide
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C30H32N4O2
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1
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| 1 |
IC50 = 1044 nM
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CP0522125
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N-(cyclopropylmethyl)-2-[6-[3-(4-hydroxypiperidin-1-yl)propoxy]-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
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C28H34N4O4
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1
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| 1 |
IC50 = 1100 nM
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CP0504626
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2-(6-(3-(aminomethyl)phenyl)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-(cyclopropylmethyl)acetamide
Show/Hide
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C27H26N4O2
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1
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| 1 |
IC50 = 1200 nM
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CP0415323
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2-[3-(3-chlorophenyl)-7-[2-(1-methylpiperidin-4-yl)ethoxy]-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
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C26H33ClN4O3
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1
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| 1 |
IC50 = 1258.93 nM
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CP0493140
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2-[3-(3-chlorophenyl)-7-[(1-methylpiperidin-4-yl)methoxy]-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
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C25H31ClN4O3
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1
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| 1 |
IC50 = 1258.93 nM
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CP0493141
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2-[3-(3-chlorophenyl)-7-[3-(dimethylamino)piperidin-1-yl]-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
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C25H32ClN5O2
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1
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| 1 |
IC50 = 1258.93 nM
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CP0507656
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2-[3-(3-chlorophenyl)-7-(9-methyl-2,9-diazaspiro[5.5]undecan-2-yl)-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
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C28H36ClN5O2
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1
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| 1 |
IC50 = 1258.93 nM
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CP0465481
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N-(cyclopropylmethyl)-2-[6-(3-morpholin-4-ylpropoxy)-4-oxo-2-pyridin-3-ylquinazolin-3-yl]acetamide
Show/Hide
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C26H31N5O4
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1
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| 1 |
IC50 = 1350 nM
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CP0438296
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N-(cyclopropylmethyl)-2-[2-(4-methylphenyl)-6-(3-morpholin-4-ylpropoxy)-4-oxoquinazolin-3-yl]acetamide
Show/Hide
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C28H34N4O4
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1
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| 1 |
IC50 = 1450 nM
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CP0492932
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N-(cyclopropylmethyl)-2-[6-[3-(4-methylpiperazin-1-yl)propoxy]-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
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C28H35N5O3
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1
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| 1 |
IC50 = 1700 nM
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CP0372672
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N-(cyclopropylmethyl)-2-[4-oxo-2-phenyl-6-(3-pyrrolidin-1-ylpropoxy)quinazolin-3-yl]acetamide
Show/Hide
|
C27H32N4O3
|
1
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| 1 |
IC50 = 1800 nM
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CP0521086
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(S)-2-(6-(2-amino-4-methylpentyloxy)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-(cyclopropylmethyl)acetamide
Show/Hide
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C26H32N4O3
|
1
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| 1 |
IC50 = 2100 nM
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CP0477711
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2-(2-(3-chlorophenyl)-4-oxo-6-(3-(piperidin-1-yl)propoxy)quinazolin-3(4H)-yl)-N-methylacetamide
Show/Hide
|
C25H29ClN4O3
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1
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| 1 |
IC50 = 2350 nM
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CP0399785
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2-(6-(3-(azetidin-1-ylmethyl)phenyl)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-propylacetamide
Show/Hide
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C29H30N4O2
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1
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| 1 |
IC50 = 2350 nM
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CP0498909
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N-(cyclopropylmethyl)-2-[6-(3-morpholin-4-ylpropoxy)-4-oxo-2-quinolin-3-ylquinazolin-3-yl]acetamide
Show/Hide
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C30H33N5O4
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1
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| 1 |
IC50 = 2400 nM
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CP0498911
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2-(2-(3-methoxyphenyl)-4-oxo-6-(3-(piperidin-1-yl)propoxy)quinazolin-3(4H)-yl)-N-methylacetamide
Show/Hide
|
C26H32N4O4
|
1
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| 1 |
IC50 = 2500 nM
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CP0530798
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2-(6-(3-(azetidin-1-ylmethyl)phenyl)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-cyclopropylacetamide
Show/Hide
|
C29H28N4O2
|
1
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| 1 |
IC50 = 2550 nM
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CP0543420
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N-(cyclopropylmethyl)-2-[6-(3-morpholin-4-ylpropoxy)-4-oxo-2-pyridin-4-ylquinazolin-3-yl]acetamide
Show/Hide
|
C26H31N5O4
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1
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| 1 |
IC50 = 3100 nM
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CP0541594
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2-(6-(3-aminopropoxy)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-(cyclopropylmethyl)acetamide
Show/Hide
|
C23H26N4O3
|
1
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| 1 |
IC50 = 3600 nM
|
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CP0531279
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N-(cyclopropylmethyl)-2-[6-[3-(diethylamino)propoxy]-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
|
C27H34N4O3
|
1
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| 1 |
IC50 = 3800 nM
|
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CP0514869
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2-[3-(3-chlorophenyl)-7-[4-[2-(dimethylamino)ethyl]piperidin-1-yl]-1-oxopyrrolo[1,2-a]pyrazin-2-yl]-N-propan-2-ylacetamide
Show/Hide
|
C27H36ClN5O2
|
1
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| 1 |
IC50 = 3981.07 nM
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CP0533336
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2-(6-(2-aminoethoxy)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-(cyclopropylmethyl)acetamide
Show/Hide
|
C22H24N4O3
|
1
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| 1 |
IC50 = 4000 nM
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CP0516864
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N-(cyclopropylmethyl)-2-[6-[4-(4-methylpiperazin-1-yl)butoxy]-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
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C29H37N5O3
|
1
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| 1 |
IC50 = 4800 nM
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CP0521085
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(S)-2-amino-N-(1-(3-(2-(cyclopropylmethylamino)-2-oxoethyl)-4-oxo-2-phenyl-3,4-dihydroquinazolin-6-yloxy)-4-methylpentan-2-yl)acetamide
Show/Hide
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C28H35N5O4
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1
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| 1 |
IC50 = 5100 nM
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CP0465483
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2-(2-(3-chlorophenyl)-6-(3-morpholinopropoxy)-4-oxoquinazolin-3(4H)-yl)-N-methylacetamide
Show/Hide
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C24H27ClN4O4
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1
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| 1 |
IC50 = 6050 nM
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CP0522124
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N-(cyclopropylmethyl)-2-[6-[3-(methylamino)propoxy]-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
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C24H28N4O3
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1
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| 1 |
IC50 = 7600 nM
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CP0424695
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2-(2-(3-chlorophenyl)-6-(3-morpholinopropoxy)-4-oxoquinazolin-3(4H)-yl)-N,N-dimethylacetamide
Show/Hide
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C25H29ClN4O4
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1
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| 1 |
IC50 > 20000 nM
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CP0487291
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2-(2-(3-methoxyphenyl)-6-(3-morpholinopropoxy)-4-oxoquinazolin-3(4H)-yl)-N,N-dimethylacetamide
Show/Hide
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C26H32N4O5
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1
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| 1 |
IC50 > 20000 nM
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CP0487293
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2-(2-(3-methoxyphenyl)-4-oxo-6-(3-(piperidin-1-yl)propoxy)quinazolin-3(4H)-yl)-N,N-dimethylacetamide
Show/Hide
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C27H34N4O4
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1
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| 1 |
IC50 > 20000 nM
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CP0505872
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2-(2-(3-chlorophenyl)-4-oxo-6-(3-(piperidin-1-yl)propoxy)quinazolin-3(4H)-yl)-N,N-dimethylacetamide
Show/Hide
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C26H31ClN4O3
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1
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| 1 |
IC50 > 20000 nM
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CP0371936
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N-(cyclopropylmethyl)-2-[6-[2-(morpholin-4-ylmethyl)phenyl]-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
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C31H32N4O3
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1
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| 1 |
IC50 > 20000 nM
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CP0371937
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N-(cyclopropylmethyl)-2-[4-oxo-2-phenyl-6-[4-(piperidin-1-ylmethyl)phenyl]quinazolin-3-yl]acetamide
Show/Hide
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C32H34N4O2
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1
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| 1 |
IC50 > 20000 nM
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CP0467683
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N-(cyclopropylmethyl)-2-[4-oxo-2-phenyl-6-[2-(piperidin-1-ylmethyl)phenyl]quinazolin-3-yl]acetamide
Show/Hide
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C32H34N4O2
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1
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| 1 |
IC50 > 20000 nM
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CP0534084
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N-(cyclopropylmethyl)-2-[6-[4-(morpholin-4-ylmethyl)phenyl]-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
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C31H32N4O3
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1
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| 1 |
IC50 > 20000 nM
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CP0501904
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N-(cyclopropylmethyl)-2-[6-[2-(4-methylpiperazin-1-yl)ethoxy]-4-oxo-2-phenylquinazolin-3-yl]acetamide
Show/Hide
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C27H33N5O3
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1
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| 1 |
IC50 = 22000 nM
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CP0479558
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N-(cyclopropylmethyl)-2-[4-oxo-2-phenyl-6-(3-piperazin-1-ylpropoxy)quinazolin-3-yl]acetamide
Show/Hide
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C27H33N5O3
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1
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| 1 |
IC50 = 25800 nM
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CP0488925
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2-(6-(4-aminobutoxy)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-(cyclopropylmethyl)acetamide
Show/Hide
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C24H28N4O3
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1
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| 1 |
IC50 > 30000 nM
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CP0513577
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2-(6-(5-aminopentyloxy)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-(cyclopropylmethyl)acetamide
Show/Hide
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C25H30N4O3
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1
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| 1 |
IC50 > 30000 nM
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CP0501903
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2-amino-N-(2-(3-(2-(cyclopropylmethylamino)-2-oxoethyl)-4-oxo-2-phenyl-3,4-dihydroquinazolin-6-yloxy)ethyl)acetamide
Show/Hide
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C24H27N5O4
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1
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| 1 |
IC50 = 30500 nM
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CP0479557
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N-(cyclopropylmethyl)-2-(6-hydroxy-4-oxo-2-phenylquinazolin-3-yl)acetamide
Show/Hide
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C20H19N3O3
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1
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| 1 |
IC50 > 100000 nM
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CP0492930
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N-[2-[3-[2-(cyclopropylmethylamino)-2-oxoethyl]-4-oxo-2-phenylquinazolin-6-yl]oxyethyl]-3-(4-hydroxyphenyl)propanamide
Show/Hide
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C31H32N4O5
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1
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| 1 |
IC50 > 100000 nM
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CP0516863
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2-(6-(6-aminohexyloxy)-4-oxo-2-phenylquinazolin-3(4H)-yl)-N-(cyclopropylmethyl)acetamide
Show/Hide
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C26H32N4O3
|
1
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| 1 |
IC50 > 100000 nM
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CP0390719
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(S)-1-((R)-5-chloro-3-(2-methoxy-5-(pyrrolidin-1-ylmethyl)phenyl)-1-(4-methoxyphenylsulfonyl)-2-oxoindolin-3-yl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
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C34H39ClN4O6S
|
1
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| 1 |
Ki = 0.03 nM
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CP0486695
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(S)-1-((R)-5-chloro-3-(2-methoxy-5-((4-methylpiperazin-1-yl)methyl)phenyl)-1-(4-methoxyphenylsulfonyl)-2-oxoindolin-3-yl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
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C35H42ClN5O6S
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1
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| 1 |
Ki = 0.03 nM
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CP0503440
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(S)-1-((R)-5-chloro-3-(2-methoxy-4-((4-methylpiperazin-1-yl)methyl)phenyl)-1-(4-methoxyphenylsulfonyl)-2-oxoindolin-3-yl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
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C35H42ClN5O6S
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1
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| 1 |
Ki = 0.04 nM
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CP0456297
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(S)-1-((R)-5-chloro-3-(2-methoxy-4-(pyrrolidin-1-ylmethyl)phenyl)-1-(4-methoxyphenylsulfonyl)-2-oxoindolin-3-yl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
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C34H39ClN4O6S
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1
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| 1 |
Ki = 0.08 nM
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CP0425070
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(2S)-2-{[(2R)-1-{[(4S,7R,10S,13R,16S)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-10-(2-methylpropyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
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C47H67N13O11S2
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1
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| 1 |
Ki = 0.23 nM
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CP0465012
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(S)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxy-5-(pyrrolidin-1-ylmethyl)phenyl)-2-oxoindolin-3-yl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
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C35H41ClN4O7S
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1
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| 1 |
Ki = 0.26 nM
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CP0372643
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-10-propan-2-yl-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C46H65N13O11S2
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1
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| 1 |
Ki = 0.29 nM
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CP0424652
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(S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((S)-1-(2-amino-2-oxoethylamino)-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
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C46H64N14O12S2
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1
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| 1 |
Ki = 0.37 nM
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CP0432651
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-10-[3-(diaminomethylideneamino)propyl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C47H68N16O11S2
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1
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| 1 |
Ki = 0.37 nM
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CP0495010
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(2R)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4S,7R,10S,13R,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-10-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C47H67N13O11S2
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1
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| 1 |
Ki = 0.42 nM
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CP0844971
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-10-butyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
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C47H67N13O11S2
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1
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| 1 |
Ki = 0.43 nM
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CP0418413
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-aminopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C46H66N14O11S2
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1
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| 1 |
Ki = 0.49 nM
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CP0875035
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-10-{4-[(diaminomethylidene)amino]butyl}-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C48H70N16O11S2
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1
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| 1 |
Ki = 0.52 nM
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CP0195952
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(2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxyphenyl)-2-oxoindolin-3-yl)-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
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C30H32ClN3O8S
|
3
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| 1 |
Ki = 0.6 nM
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| 2 |
Ki = 1.7 nM
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| 3 |
Ki = 58.88 nM
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CP0441988
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2-((S)-2-((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-6-(7-aminoheptanamido)hexanamido)acetic acid
Show/Hide
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C54H79N11O13S2
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1
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| 1 |
Ki = 0.61 nM
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CP0907711
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-10-propyl-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C46H65N13O11S2
|
1
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| 1 |
Ki = 0.78 nM
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CP0498370
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(S)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxy-4-(pyrrolidin-1-ylmethyl)phenyl)-2-oxoindolin-3-yl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C35H41ClN4O7S
|
1
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| 1 |
Ki = 0.81 nM
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CP0911177
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-10-(1-hydroxyethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C45H63N13O12S2
|
1
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| 1 |
Ki = 1 nM
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CP0434598
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3-(6-chloro-2-ethoxypyridin-3-yl)-1-(5-methoxypyridin-2-yl)sulfonyl-2-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)indole-5-carbonitrile
Show/Hide
|
C31H28ClN7O5S
|
1
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| 1 |
Ki = 1.1 nM
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CP0405364
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-10-(cyclohexylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
|
C50H71N13O11S2
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1
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| 1 |
Ki = 1.2 nM
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CP0918735
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-10-ethyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C45H63N13O11S2
|
1
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| 1 |
Ki = 1.2 nM
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CP0482229
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(R)-5-chloro-3-(2-methoxy-5-(pyrrolidin-1-ylmethyl)phenyl)-1-(4-methoxyphenylsulfonyl)-3-((S)-2-(oxazol-2-yl)pyrrolidin-1-yl)indolin-2-one
Show/Hide
|
C34H35ClN4O6S
|
1
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| 1 |
Ki = 1.2 nM
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CP0441987
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2-((S)-2-((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-6-(3-aminopropanamido)hexanamido)acetic acid
Show/Hide
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C50H71N11O13S2
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1
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| 1 |
Ki = 1.3 nM
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|
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CP0456409
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(2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxypyridin-3-yl)-2-oxoindolin-3-yl)-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C29H31ClN4O8S
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1
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| 1 |
Ki = 1.3 nM
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|
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CP0462769
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(R)-5-chloro-3-(2-methoxy-5-((4-methylpiperazin-1-yl)methyl)phenyl)-1-(4-methoxyphenylsulfonyl)-3-((S)-2-(oxazol-2-yl)pyrrolidin-1-yl)indolin-2-one
Show/Hide
|
C35H38ClN5O6S
|
1
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| 1 |
Ki = 1.3 nM
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|
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CP0868672
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7,10-bis(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C45H62N14O12S2
|
1
|
| 1 |
Ki = 1.5 nM
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|
|
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CP0479072
|
2-((2S)-6-amino-2-((2S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-19-hydroxy-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)hexanamido)acetic acid
Show/Hide
|
C47H66N10O13S2
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1
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| 1 |
Ki = 1.7 nM
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|
|
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CP0845005
|
(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-10-(4-aminobutyl)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C47H68N14O11S2
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1
|
| 1 |
Ki = 1.8 nM
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|
|
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CP0844981
|
(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-10-(hydroxymethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C44H61N13O12S2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
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CP0462768
|
(R)-5-chloro-3-(5-((dimethylamino)methyl)-2-methoxyphenyl)-1-(4-methoxyphenylsulfonyl)-3-((S)-2-(oxazol-2-yl)pyrrolidin-1-yl)indolin-2-one
Show/Hide
|
C32H33ClN4O6S
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0432341
|
3-(2-ethoxy-5-methoxyphenyl)-1-(5-methoxyquinolin-8-yl)sulfonyl-2-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)indole-5-carbonitrile
Show/Hide
|
C37H34N6O6S
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0572685
|
3-(2-ethoxy-5-methoxyphenyl)-1-(5-methoxypyridin-2-yl)sulfonyl-2-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)indole-5-carbonitrile
Show/Hide
|
C33H32N6O6S
|
1
|
| 1 |
Ki = 2 nM
|
|
|
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CP0422022
|
(2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(4-methoxypyridin-3-yl)-2-oxoindolin-3-yl)-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C29H31ClN4O8S
|
1
|
| 1 |
Ki = 2.1 nM
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|
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CP0844973
|
(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-10-(aminomethyl)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C44H62N14O11S2
|
1
|
| 1 |
Ki = 3.4 nM
|
|
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CP0495187
|
2-((S)-2-((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-6-(11-aminoundecanamido)hexanamido)acetic acid
Show/Hide
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C58H87N11O13S2
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0465011
|
(S)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxypyridin-3-yl)-2-oxoindolin-3-yl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C29H31ClN4O7S
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0390720
|
(R)-5-chloro-3-(2-methoxy-5-((methylamino)methyl)phenyl)-1-(4-methoxyphenylsulfonyl)-3-((S)-2-(oxazol-2-yl)pyrrolidin-1-yl)indolin-2-one
Show/Hide
|
C31H31ClN4O6S
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0899715
|
(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-10-(thiophen-2-ylmethyl)-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C48H63N13O11S3
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0411994
|
3-(2-ethoxy-5-methoxyphenyl)-2-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)-1-quinolin-8-ylsulfonylindole-5-carbonitrile
Show/Hide
|
C36H32N6O5S
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0478219
|
(2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2,4-dimethoxypyrimidin-5-yl)-2-oxoindolin-3-yl)-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C29H32ClN5O9S
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0379479
|
(S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((R)-1-(2-amino-2-oxoethylamino)-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C46H64N14O12S2
|
1
|
| 1 |
Ki = 5.8 nM
|
|
|
|
CP0409447
|
(HO-LVA23)2-{2-[3-(4-Hydroxy-phenyl)-2-(methyl-4-Hydroxy-phenylacetyl-amino)-propionylamino]-3-phenyl-propionylamino}-pentanedioic acid 5-amide 1-[(2-carbamoyl-1-{1-[2-(1-carbamoyl-4-guanidino-butylcarbamoyl)-pyrrolidine-1-carbonyl]-4-guanidino-butylcarbamoyl}-ethyl)-amide]
Show/Hide
|
C53H74N16O12
|
1
|
| 1 |
Ki = 5.9 nM
|
|
|
|
CP0439670
|
(2S)-2-{[(2R)-1-{[(4S,7R,10S,13R,16S)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-10-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C44H61N13O11S2
|
1
|
| 1 |
Ki = 6.5 nM
|
|
|
|
CP0897831
|
(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-10-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C52H66N14O11S2
|
1
|
| 1 |
Ki = 7.8 nM
|
|
|
|
CP0432340
|
5-chloro-3-(2-methoxyphenyl)-3-(4-pyridin-3-ylpiperazin-1-yl)-1-quinolin-8-ylsulfonylindol-2-one
Show/Hide
|
C33H28ClN5O4S
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0494303
|
2-((2S)-2-((2S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-19-hydroxy-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-6-(11-aminoundecanamido)hexanamido)acetic acid
Show/Hide
|
C58H87N11O14S2
|
1
|
| 1 |
Ki = 8.4 nM
|
|
|
|
CP0458050
|
3-(2-ethoxy-5-methoxyphenyl)-1-(5-fluoroquinolin-8-yl)sulfonyl-2-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)indole-5-carbonitrile
Show/Hide
|
C36H31FN6O5S
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0421138
|
(LVA)2-{2-[3-(4-Hydroxy-phenyl)-2-(methyl-phenylacetyl-amino)-propionylamino]-3-phenyl-propionylamino}-pentanedioic acid 5-amide 1-[(2-carbamoyl-1-{1-[2-(1-carbamoyl-4-guanidino-butylcarbamoyl)-pyrrolidine-1-carbonyl]-4-guanidino-butylcarbamoyl}-ethyl)-amide]
Show/Hide
|
C53H74N16O11
|
1
|
| 1 |
Ki = 9.4 nM
|
|
|
|
CP0844972
|
(2S)-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]-2-{[(2R)-1-{[(4S,7R,13R,16S)-10,13-dibenzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}pentanamide
Show/Hide
|
C50H65N13O11S2
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
|
CP0434595
|
1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-ethoxy-4-methoxyphenyl)-2-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)indole-5-carbonitrile
Show/Hide
|
C35H35N5O7S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0870976
|
(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-10-(2-aminoethyl)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C45H64N14O11S2
|
1
|
| 1 |
Ki = 12.8 nM
|
|
|
|
CP0411992
|
3-(2,5-dimethoxyphenyl)-1-(2,4-dimethoxyphenyl)sulfonyl-2-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)indole-5-carbonitrile
Show/Hide
|
C34H33N5O7S
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0844975
|
(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-10,16-bis[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C50H65N13O12S2
|
1
|
| 1 |
Ki = 14.8 nM
|
|
|
|
CP0572691
|
5-chloro-3-(2-methoxypyridin-3-yl)-3-(4-pyridin-3-ylpiperazin-1-yl)-1-quinolin-8-ylsulfonylindol-2-one
Show/Hide
|
C32H27ClN6O4S
|
1
|
| 1 |
Ki = 15.2 nM
|
|
|
|
CP0536773
|
5-chloro-1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-methoxyphenyl)-3-(4-pyridin-3-ylpiperazin-1-yl)indol-2-one
Show/Hide
|
C32H31ClN4O6S
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0390758
|
(R)-5-chloro-1-(4-methoxyphenylsulfonyl)-3-(2-methoxypyridin-3-yl)-3-((S)-2-(oxazol-2-yl)pyrrolidin-1-yl)indolin-2-one
Show/Hide
|
C28H25ClN4O6S
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0487321
|
1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-ethoxy-5-methoxyphenyl)-2-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)indole-5-carbonitrile
Show/Hide
|
C35H35N5O7S
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0456966
|
(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C43H59N13O11S2
|
1
|
| 1 |
Ki = 22.9 nM
|
|
|
|
CP0436858
|
N-cyclopentyl-4-methoxy-N-[[2-[4-[(2-methylpropylamino)methyl]phenyl]-1,3-thiazol-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C27H35N3O3S2
|
1
|
| 1 |
Ki = 25.12 nM
|
|
|
|
CP0465013
|
(2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(3-methoxypyrazin-2-yl)-2-oxoindolin-3-yl)-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C28H30ClN5O8S
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0392674
|
4HOPh(CH2)2CO-DTyr(Me)-Phe-Gln-Asn-Arg-Pro-Lys(5C-Rhm)-NH2
Show/Hide
|
C79H96N16O16
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0572684
|
3-(2-methoxypyridin-3-yl)-2-oxo-3-(4-pyridin-3-ylpiperazin-1-yl)-1-quinolin-8-ylsulfonylindole-5-carbonitrile
Show/Hide
|
C33H27N7O4S
|
1
|
| 1 |
Ki = 30.2 nM
|
|
|
|
CP0572686
|
3-(2-ethoxy-5-methoxyphenyl)-1-(4-methoxyphenyl)sulfonyl-2-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)indole-5-carbonitrile
Show/Hide
|
C34H33N5O6S
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0411991
|
1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-ethoxyphenyl)-2-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)indole-5-carbonitrile
Show/Hide
|
C34H33N5O6S
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0434593
|
5-chloro-1-(2,4-dimethoxyphenyl)sulfonyl-3-[(2R)-2,4-dimethyl-3-oxopiperazin-1-yl]-3-(2-methoxypyridin-3-yl)indol-2-one
Show/Hide
|
C28H29ClN4O7S
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0401557
|
N-(cyclohexylmethyl)-1-[2-[1-(2,4-dimethoxyphenyl)sulfonyl-3,4-dihydro-2H-quinolin-2-yl]ethylsulfonyl]piperidin-4-amine
Show/Hide
|
C31H45N3O6S2
|
1
|
| 1 |
Ki = 43.65 nM
|
|
|
|
CP0434597
|
3-(6-chloro-2-ethoxypyridin-3-yl)-1-(2,4-dimethoxyphenyl)sulfonyl-2-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)indole-5-carbonitrile
Show/Hide
|
C33H31ClN6O6S
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0552243
|
5-chloro-1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-methoxypyridin-3-yl)-3-(4-pyridin-3-ylpiperazin-1-yl)indol-2-one
Show/Hide
|
C31H30ClN5O6S
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0458047
|
5-chloro-3-(2-methoxyphenyl)-1-(2-methoxyphenyl)sulfonyl-3-(4-pyridin-3-ylpiperazin-1-yl)indol-2-one
Show/Hide
|
C31H29ClN4O5S
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0434594
|
1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-methoxyphenyl)-2-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)indole-5-carbonitrile
Show/Hide
|
C33H31N5O6S
|
1
|
| 1 |
Ki = 58.5 nM
|
|
|
|
CP0498628
|
(2S)-N-(3-(1-aminoisoquinolin-6-yl)-1-oxo-1-(piperidin-1-yl)propan-2-yl)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)-3-phenylpropanamide
Show/Hide
|
C36H43N5O5S
|
1
|
| 1 |
Ki = 63 nM
|
|
|
|
CP0572690
|
5-chloro-1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-methoxypyridin-3-yl)-3-(3-oxo-4-pyridin-3-ylpiperazin-1-yl)indol-2-one
Show/Hide
|
C31H28ClN5O7S
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0405349
|
1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-ethoxypyridin-3-yl)-2-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)indole-5-carbonitrile
Show/Hide
|
C33H32N6O6S
|
1
|
| 1 |
Ki = 84 nM
|
|
|
|
CP0898453
|
[Lys8(Alexa 488)]PVA
Show/Hide
|
C94H122Cl3N17O23S3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0373513
|
N-cyclopentyl-N-[[2-[4-(diethylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]-4-methoxybenzenesulfonamide
Show/Hide
|
C27H35N3O3S2
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0468260
|
N-cyclopentyl-4-methoxy-N-[[2-[4-(propylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C26H33N3O3S2
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0468263
|
N-[4-[[cyclopentyl-(4-methoxyphenyl)sulfonylamino]methyl]-1,3-thiazol-2-yl]pyridine-3-carboxamide
Show/Hide
|
C22H24N4O4S2
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0478455
|
N-cyclopentyl-N-[[2-[4-[(2,2-dimethylpropylamino)methyl]phenyl]-1,3-thiazol-4-yl]methyl]-4-methoxybenzenesulfonamide
Show/Hide
|
C28H37N3O3S2
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0478202
|
(+/-)-(3R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxypyridin-3-yl)-3-(2-(oxazol-2-yl)pyrrolidin-1-yl)indolin-2-one
Show/Hide
|
C29H27ClN4O7S
|
1
|
| 1 |
Ki = 101 nM
|
|
|
|
CP0411989
|
5-chloro-3-(2-methoxyphenyl)-1-(4-methoxyphenyl)sulfonyl-3-(4-pyridin-3-ylpiperazin-1-yl)indol-2-one
Show/Hide
|
C31H29ClN4O5S
|
1
|
| 1 |
Ki = 104 nM
|
|
|
|
CP0517168
|
N-[[2-[4-(butylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]-4-methoxy-N-(oxan-4-yl)benzenesulfonamide
Show/Hide
|
C27H35N3O4S2
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0392420
|
4HOPh(CH2)2CO-DTyr(Me)-Phe-Gln-Asn-Arg-Pro-Lys(5C-Flu)-NH2
Show/Hide
|
C75H86N14O18
|
1
|
| 1 |
Ki = 142 nM
|
|
|
|
CP0869924
|
triethylamine hemi(2-((2S)-2-((2S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-19-hydroxy-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-6-(2-(6-amino-3-imino-4,5-disulfonato-3H-xanthen-9-yl)-5-((2,3,5,6-tetrafluorophenoxy)carbonyl)benzamido)hexanamido)acetate)
Show/Hide
|
C68H76Li2N12O23S4
|
1
|
| 1 |
Ki = 149 nM
|
|
|
|
CP0853921
|
3-[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-4-{[(2R)-2-{[(1S)-1-[(carbamoylmethyl)carbamoyl]-4-[(diaminomethylidene)amino]butyl]carbamoyl}pyrrolidin-1-yl]carbonyl}-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-10-yl]propanoic acid
Show/Hide
|
C46H63N13O13S2
|
1
|
| 1 |
Ki = 156 nM
|
|
|
|
CP0503557
|
N-[[2-[4-(butylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]-N-cyclopentyl-4-methoxybenzenesulfonamide
Show/Hide
|
C27H35N3O3S2
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0508670
|
N-[4-[[cyclopentyl-(4-methoxyphenyl)sulfonylamino]methyl]-1,3-thiazol-2-yl]pyridine-4-carboxamide
Show/Hide
|
C22H24N4O4S2
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0465004
|
1-(1,4-diazepan-1-yl)-2-(5-methoxy-1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2-methyl-1H-indol-3-yl)ethanone
Show/Hide
|
C26H33N3O5S
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0487320
|
5-chloro-1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-methoxypyridin-3-yl)-3-(4-methyl-3-oxopiperazin-1-yl)indol-2-one
Show/Hide
|
C27H27ClN4O7S
|
1
|
| 1 |
Ki = 192 nM
|
|
|
|
CP0536774
|
1-(benzenesulfonyl)-5-chloro-3-(2-methoxyphenyl)-3-(4-pyridin-3-ylpiperazin-1-yl)indol-2-one
Show/Hide
|
C30H27ClN4O4S
|
1
|
| 1 |
Ki = 233 nM
|
|
|
|
CP0498625
|
(S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)-N-(3-(4-methylpiperazin-1-yl)propyl)-3-phenylpropanamide
Show/Hide
|
C27H40N4O4S
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0522286
|
N-[3-[[2-[4-(butylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl-cyclopentylsulfamoyl]phenyl]acetamide
Show/Hide
|
C28H36N4O3S2
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0456296
|
2-(5-fluoro-1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2-methyl-1H-indol-3-yl)-N-methyl-N-(2-(pyridin-2-yl)ethyl)acetamide
Show/Hide
|
C28H30FN3O4S
|
1
|
| 1 |
Ki = 260 nM
|
|
|
|
CP0505809
|
(+/-)-(3R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxypyridin-3-yl)-3-(2-(thiazol-2-yl)pyrrolidin-1-yl)indolin-2-one
Show/Hide
|
C29H27ClN4O6S2
|
1
|
| 1 |
Ki = 276 nM
|
|
|
|
CP0498627
|
(1,4-diazepan-1-yl)(5-fluoro-1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2-methyl-1H-indol-3-yl)methanone
Show/Hide
|
C24H28FN3O4S
|
1
|
| 1 |
Ki = 310 nM
|
|
|
|
CP0373637
|
N-[4-[[cyclopentyl-(4-methoxyphenyl)sulfonylamino]methyl]-1,3-thiazol-2-yl]-2-methylpropanamide
Show/Hide
|
C20H27N3O4S2
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0468261
|
N-[[2-[4-[(cyclohexylmethylamino)methyl]phenyl]-1,3-thiazol-4-yl]methyl]-N-cyclopentyl-4-methoxybenzenesulfonamide
Show/Hide
|
C30H39N3O3S2
|
1
|
| 1 |
Ki = 316.23 nM
|
|
|
|
CP0501330
|
N-[4-[[cyclopentyl-(4-methoxyphenyl)sulfonylamino]methyl]-1,3-thiazol-2-yl]-4-methoxybenzamide
Show/Hide
|
C24H27N3O5S2
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0503556
|
N-cyclopentyl-N-[[2-[4-[(furan-3-ylmethylamino)methyl]phenyl]-1,3-thiazol-4-yl]methyl]-4-methoxybenzenesulfonamide
Show/Hide
|
C28H31N3O4S2
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0511626
|
N-[[6-[4-(butylaminomethyl)phenyl]pyridin-2-yl]methyl]-N-cyclopentyl-4-methoxybenzenesulfonamide
Show/Hide
|
C29H37N3O3S
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0523427
|
N-[[2-[4-(butylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]-N-cyclopentyl-4-fluorobenzenesulfonamide
Show/Hide
|
C26H32FN3O2S2
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0534234
|
2-(5-fluoro-1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2-methyl-1H-indol-3-yl)-N-(3-(4-methylpiperazin-1-yl)propyl)acetamide
Show/Hide
|
C28H37FN4O4S
|
1
|
| 1 |
Ki = 430 nM
|
|
|
|
CP0498624
|
(S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)-N-(2-(4-methylpiperazin-1-yl)ethyl)-3-phenylpropanamide
Show/Hide
|
C26H38N4O4S
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0530499
|
(1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2-methyl-1H-indol-3-yl)(4-methyl-1,4-diazepan-1-yl)methanone
Show/Hide
|
C25H31N3O4S
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0373514
|
4-[4-[[cyclopentyl-(4-methoxyphenyl)sulfonylamino]methyl]-1,3-thiazol-2-yl]benzamide
Show/Hide
|
C23H25N3O4S2
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0517166
|
N-[[2-[4-(butylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]-N-cyclopentyl-3-methoxybenzenesulfonamide
Show/Hide
|
C27H35N3O3S2
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0498972
|
1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2-methyl-N-(3-(4-methylpiperazin-1-yl)propyl)-1H-indole-3-carboxamide
Show/Hide
|
C27H36N4O4S
|
1
|
| 1 |
Ki = 560 nM
|
|
|
|
CP0534232
|
(S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)-N-((S)-1-oxo-3-phenyl-1-(piperidin-1-yl)propan-2-yl)-3-phenylpropanamide
Show/Hide
|
C33H41N3O5S
|
1
|
| 1 |
Ki = 630 nM
|
|
|
|
CP0468262
|
4-[4-[[cyclopentyl-(4-methoxyphenyl)sulfonylamino]methyl]-1,3-thiazol-2-yl]-N,N-dimethylbenzamide
Show/Hide
|
C25H29N3O4S2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0478454
|
N-[[2-[4-(butylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]-4-methoxy-N-[(3R)-oxolan-3-yl]benzenesulfonamide
Show/Hide
|
C26H33N3O4S2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0527068
|
N-[[2-[4-(butylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]-N-cyclopentylbenzenesulfonamide
Show/Hide
|
C26H33N3O2S2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0528753
|
(+/-)-(3R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxypyridin-3-yl)-3-(2-(pyridin-2-yl)pyrrolidin-1-yl)indolin-2-one
Show/Hide
|
C31H29ClN4O6S
|
1
|
| 1 |
Ki = 786 nM
|
|
|
|
CP0486822
|
(1,4-diazepan-1-yl)(1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2,5-dimethyl-1H-indol-3-yl)methanone
Show/Hide
|
C25H31N3O4S
|
1
|
| 1 |
Ki = 790 nM
|
|
|
|
CP0373515
|
4-[4-[[cyclopentyl-(4-methoxyphenyl)sulfonylamino]methyl]-1,3-thiazol-2-yl]benzoic acid
Show/Hide
|
C23H24N2O5S2
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0517164
|
N-[[4-[4-(butylaminomethyl)phenyl]thiophen-2-yl]methyl]-N-cyclopentyl-4-methoxybenzenesulfonamide
Show/Hide
|
C28H36N2O3S2
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0511628
|
N-[[3-[4-(butylaminomethyl)phenyl]-4-fluorophenyl]methyl]-N-cyclopentyl-4-methoxybenzenesulfonamide
Show/Hide
|
C30H37FN2O3S
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0555167
|
(S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)-N-methyl-N-(3-(4-methylpiperazin-1-yl)propyl)-3-phenylpropanamide
Show/Hide
|
C28H42N4O4S
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0349430
|
1-(4-methoxy-2,3-dimethylphenylsulfonyl)-N-(3-(4-methylpiperazin-1-yl)propyl)indoline-3-carboxamide
Show/Hide
|
C26H36N4O4S
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
|
CP0388756
|
N-(cyclopropylmethyl)-3-methyl-N-(oxolan-2-ylmethyl)-4-phenylbenzamide
Show/Hide
|
C23H27NO2
|
2
|
| 1 |
Ki = 1258.93 nM
|
|
|
| 2 |
Ki > 12589.25 nM
|
|
|
|
CP0373639
|
N-[[2-[4-(butylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]-N-(1,1-dioxothiolan-3-yl)-4-methoxybenzenesulfonamide
Show/Hide
|
C26H33N3O5S3
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0378721
|
N-[[2-[4-(butylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]-N-cyclopentyl-4-propan-2-yloxybenzenesulfonamide
Show/Hide
|
C29H39N3O3S2
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0514897
|
N-[[2-[4-(butylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]-N-cyclopentyl-2-methoxybenzenesulfonamide
Show/Hide
|
C27H35N3O3S2
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0538832
|
N-[1-[6-[4-(butylaminomethyl)phenyl]pyridin-2-yl]ethyl]-N-cyclopentyl-4-methoxybenzenesulfonamide
Show/Hide
|
C30H39N3O3S
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0538834
|
N-[[2-[4-(butylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]-N-cyclopentyl-3,4-dimethoxybenzenesulfonamide
Show/Hide
|
C28H37N3O4S2
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0499742
|
(2S)-N-benzyl-3-(4-chlorophenyl)-2-[(4-methoxy-2,3,6-trimethylphenyl)sulfonylamino]-N-[3-(4-methylpiperazin-1-yl)propyl]propanamide
Show/Hide
|
C34H45ClN4O4S
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0405347
|
5-chloro-1-(2,4-dimethoxyphenyl)sulfonyl-3-(2-methoxypyridin-3-yl)-3-(3-oxopiperazin-1-yl)indol-2-one
Show/Hide
|
C26H25ClN4O7S
|
1
|
| 1 |
Ki = 1340 nM
|
|
|
|
CP0517167
|
N-[[2-[4-(butylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]-N-cyclopentyl-4-(trifluoromethoxy)benzenesulfonamide
Show/Hide
|
C27H32F3N3O3S2
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0555133
|
(S)-N-(3-(dimethylamino)propyl)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)-3-phenylpropanamide
Show/Hide
|
C24H35N3O4S
|
1
|
| 1 |
Ki = 2000 nM
|
|
|
|
CP0498626
|
(S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)-N-(3-(4-methylpiperidin-1-yl)propyl)-3-phenylpropanamide
Show/Hide
|
C28H41N3O4S
|
1
|
| 1 |
Ki = 2500 nM
|
|
|
|
CP0373642
|
N-cyclopentyl-4-methoxy-N-[[2-[4-[[(4-methoxyphenyl)methylamino]methyl]phenyl]-1,3-thiazol-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C31H35N3O4S2
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0517165
|
N-[[5-[4-(butylaminomethyl)phenyl]-2-fluorophenyl]methyl]-N-cyclopentyl-4-methoxybenzenesulfonamide
Show/Hide
|
C30H37FN2O3S
|
1
|
| 1 |
Ki = 3162.28 nM
|
|
|
|
CP0534233
|
(S)-4-methoxy-2,3,6-trimethyl-N-(1-(4-methyl-1,4-diazepan-1-yl)-1-oxo-3-phenylpropan-2-yl)benzenesulfonamide
Show/Hide
|
C25H35N3O4S
|
1
|
| 1 |
Ki = 3200 nM
|
|
|
|
CP0302223
|
(Z)-3-(4-(N-(4-chlorophenyl)-N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)sulfamoyl)phenyl)-N-(3-(dimethylamino)propyl)propanamide
Show/Hide
|
C30H33ClN6O5S
|
1
|
| 1 |
Ki = 3539 nM
|
|
|
|
CP0070065
|
4-ethoxy-N-(2-oxo-2-(2-(2-oxoindolin-3-ylidene)hydrazinyl)ethyl)-N-p-tolylbenzenesulfonamide
Show/Hide
|
C25H24N4O5S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0194007
|
5-(3-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-5-(methoxymethyl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridine
Show/Hide
|
C19H19ClFN5O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0292348
|
2-(4-fluoro-2-methylphenyl)-5-(4-(6-methoxypyridin-3-yl)-5-methyl-4H-1,2,4-triazol-3-yl)pyrazine
Show/Hide
|
C20H17FN6O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0331982
|
5-(3-(4-ethoxy-3-methylphenyl)-5-(ethoxymethyl)-4H-1,2,4-triazol-4-yl)-2-methoxypyridine
Show/Hide
|
C20H24N4O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0415340
|
2-methoxy-5-(3-(2'-methoxybiphenyl-4-yl)-5-methyl-4H-1,2,4-triazol-4-yl)pyridine
Show/Hide
|
C22H20N4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0372122
|
CHEMBL1774023
Show/Hide
|
C24H27Cl2N3O2
|
1
|
| 1 |
Ki >= 10000 nM
|
|
|
|
CP0378123
|
CHEMBL1774024
Show/Hide
|
C26H29Cl2N3O2
|
1
|
| 1 |
Ki >= 10000 nM
|
|
|
|
CP0467686
|
(S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)-N-(3-morpholinopropyl)-3-phenylpropanamide
Show/Hide
|
C26H37N3O5S
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0476817
|
(S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)-N-((S)-3-(naphthalen-2-yl)-1-oxo-1-(piperidin-1-yl)propan-2-yl)-3-phenylpropanamide
Show/Hide
|
C37H43N3O5S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0486821
|
(S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)-N-((R)-1-oxo-3-phenyl-1-(piperidin-1-yl)propan-2-yl)-3-phenylpropanamide
Show/Hide
|
C33H41N3O5S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0524484
|
(S)-2-(4-methoxy-2,3,6-trimethylphenylsulfonamido)-N-(2-oxo-2-(piperidin-1-yl)ethyl)-3-phenylpropanamide
Show/Hide
|
C26H35N3O5S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0532416
|
(+/-)-(3R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxypyridin-3-yl)-3-(2-phenylpyrrolidin-1-yl)indolin-2-one
Show/Hide
|
C32H30ClN3O6S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0532417
|
(+/-)-(3R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxypyridin-3-yl)-3-(2-(thiophen-2-yl)pyrrolidin-1-yl)indolin-2-one
Show/Hide
|
C30H28ClN3O6S2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0452018
|
N-[(2R)-3-(4-chlorophenyl)-1-[[4-(dimethylamino)cyclohexyl]amino]-1-oxopropan-2-yl]-1-(4-fluorophenyl)cyclopropane-1-carboxamide
Show/Hide
|
C27H33ClFN3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0376807
|
2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]-5-[2-[2-[2-[2-[4-[[[4-oxo-4-[[1-[4-[(2-phenylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]butanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethylsulfamoyl]benzenesulfonate
Show/Hide
|
C72H80N10O13S2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0376808
|
2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]-5-[2-[2-[2-[2-[4-[[[4-[[1-[4-[(2-methylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]-4-oxobutanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethylsulfamoyl]benzenesulfonate
Show/Hide
|
C67H78N10O13S2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0376809
|
2-(3-hydroxy-6-oxoxanthen-9-yl)-5-[2-[2-[2-[2-[4-[[[4-oxo-4-[[1-[4-[(2-phenylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]butanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethylcarbamothioylamino]benzoic acid
Show/Hide
|
C66H63N9O12S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0376810
|
4-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]-3-[2-[2-[2-[2-[4-[[[4-[[1-[4-[(2-methylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]-4-oxobutanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethylsulfamoyl]benzenesulfonate
Show/Hide
|
C67H78N10O13S2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0381621
|
1-ethyl-2-[(1E,3E,5Z)-5-[1-ethyl-3-methyl-3-[4-oxo-4-[2-[4-[[[4-oxo-4-[[1-[4-[(2-phenylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]butanoyl]amino]methyl]triazol-1-yl]ethylamino]butyl]-5-sulfoindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-5-sulfonate
Show/Hide
|
C71H76N10O11S2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0392288
|
1-ethyl-2-[(1E,3E,5E)-5-[1-ethyl-3-methyl-3-[4-oxo-4-[2-[2-[2-[2-[4-[[[4-oxo-4-[[1-[4-[(2-phenylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]butanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethylamino]butyl]-5-sulfoindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-5-sulfonate
Show/Hide
|
C77H88N10O14S2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0452234
|
4-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]-3-[2-[2-[2-[2-[4-[[[4-oxo-4-[[1-[4-[(2-phenylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]butanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethylsulfamoyl]benzenesulfonate
Show/Hide
|
C72H80N10O13S2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0474073
|
N-[4-[(5Z)-4,4-difluoro-5-[2-oxo-2-(4-piperidin-1-ylpiperidin-1-yl)ethylidene]-2,3-dihydro-1-benzazepine-1-carbonyl]phenyl]-2-methylfuran-3-carboxamide
Show/Hide
|
C35H38F2N4O4
|
1
|
| 1 |
Ki = 25500 nM
|
|
|
|
CP0873189
|
[Lys8(Alexa 546)]PVA
Show/Hide
|
C75H88N16O22S2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
