| Compound ID |
Compound Name |
Compound Formula |
|
CP0474276
|
(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-cyclohexyl-1-oxopropan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C46H69N11O12S2
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1
|
| 1 |
EC50 = 0.01 nM
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|
|
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CP0387235
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(2S,4R)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(3S,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-hydroxyphenyl)methyl]-5,8,11,14,17,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-3-carbonyl]-4-hydroxypyrrolidine-2-carboxamide
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C44H66N12O14
|
1
|
| 1 |
EC50 = 0.013 nM
|
|
|
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CP0405639
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C40H61N11O12S2
|
1
|
| 1 |
EC50 = 0.013 nM
|
|
|
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CP0513588
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N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]piperidine-2-carboxamide
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C44H67N11O12S2
|
1
|
| 1 |
EC50 = 0.013 nM
|
|
|
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CP0412930
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-methyl-1-oxobutan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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|
C42H63N11O12S2
|
1
|
| 1 |
EC50 = 0.014 nM
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|
|
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CP0387240
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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|
C43H65N11O12S2
|
1
|
| 1 |
EC50 = 0.015 nM
|
|
|
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CP0493412
|
(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxopropan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C40H59N11O12S2
|
1
|
| 1 |
EC50 = 0.021 nM
|
|
|
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CP0393837
|
(2S)-N-[1-[(2-amino-2-oxoethyl)amino]-1-oxooctan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
|
C45H69N11O12S2
|
1
|
| 1 |
EC50 = 0.027 nM
|
|
|
|
CP0474277
|
(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxooctan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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|
C45H69N11O12S2
|
1
|
| 1 |
EC50 = 0.027 nM
|
|
|
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CP0394554
|
(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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|
C43H66N14O12S2
|
1
|
| 1 |
EC50 = 0.03 nM
|
|
|
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CP0539208
|
(2S,4R)-1-[(3S,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-hydroxyphenyl)methyl]-5,8,11,14,17,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-3-carbonyl]-N-[(2S)-1-(2-carbamoylhydrazinyl)-4-methyl-1-oxopentan-2-yl]-4-hydroxypyrrolidine-2-carboxamide
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C43H65N13O14
|
1
|
| 1 |
EC50 = 0.031 nM
|
|
|
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CP0117986
|
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C43H66N12O12S2
|
4
|
| 1 |
EC50 = 0.04 nM
|
|
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| 2 |
EC50 = 0.3 nM
|
|
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| 3 |
EC50 = 10.8 nM
|
|
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| 4 |
Ki = 0.44 nM
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CP0374453
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
|
C43H65N11O12S2
|
2
|
| 1 |
EC50 = 0.04 nM
|
|
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| 2 |
Ki = 0.33 nM
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|
|
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CP0412929
|
(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-N-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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|
C42H65N11O13S2
|
1
|
| 1 |
EC50 = 0.042 nM
|
|
|
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CP0412915
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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|
C46H63N11O12S2
|
1
|
| 1 |
EC50 = 0.054 nM
|
|
|
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CP0387247
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-hydroxy-1-oxopropan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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|
C40H59N11O13S2
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1
|
| 1 |
EC50 = 0.056 nM
|
|
|
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CP0393783
|
(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C41H63N11O12S2
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1
|
| 1 |
EC50 = 0.07 nM
|
|
|
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CP0535772
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-10-(hydroxymethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C41H62N10O12S2
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1
|
| 1 |
EC50 = 0.072 nM
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|
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CP0437082
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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|
C41H63N11O13S2
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1
|
| 1 |
EC50 = 0.082 nM
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|
|
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CP0437089
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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|
C46H63N11O12S2
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1
|
| 1 |
EC50 = 0.11 nM
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|
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CP0437092
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-N-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C42H65N11O12S2
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1
|
| 1 |
EC50 = 0.11 nM
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|
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CP0387237
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(2S)-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)-methylamino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C44H67N11O12S2
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1
|
| 1 |
EC50 = 0.12 nM
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|
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CP0393838
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(3S,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-hydroxyphenyl)methyl]-5,8,11,14,17,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-3-carbonyl]pyrrolidine-2-carboxamide
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|
C44H66N12O13
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1
|
| 1 |
EC50 = 0.12 nM
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|
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CP0437091
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C47H67N11O12S2
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1
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| 1 |
EC50 = 0.12 nM
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|
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CP0854838
|
sulfane
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H6S3
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1
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| 1 |
EC50 = 0.12 nM
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CP0437084
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-benzyl-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C43H65N11O11S2
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1
|
| 1 |
EC50 = 0.19 nM
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CP0541785
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-13-(2-methylpropyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C43H65N11O12S2
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1
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| 1 |
EC50 = 0.19 nM
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CP0437090
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-10-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C41H62N10O11S2
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1
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| 1 |
EC50 = 0.24 nM
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CP0474279
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(4S)-5-[(2-amino-2-oxoethyl)amino]-4-[[(2S)-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoic acid
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C42H61N11O14S2
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1
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| 1 |
EC50 = 0.25 nM
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CP0493475
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4,4-dimethyl-1-oxopentan-2-yl]-1-[(3S,6S,9S,12S,15S)-6-(2-amino-2-oxoethyl)-9-(3-amino-3-oxopropyl)-12-[(2S)-butan-2-yl]-15-[(4-hydroxyphenyl)methyl]-5,8,11,14,17,20-hexaoxo-1,4,7,10,13,16-hexazacycloicosane-3-carbonyl]pyrrolidine-2-carboxamide
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C45H68N12O13
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1
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| 1 |
EC50 = 0.26 nM
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CP0459452
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-5-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C44H67N11O12S2
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1
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| 1 |
EC50 = 0.29 nM
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CP0493480
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(4S)-5-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-4-[[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-5-oxopentanoic acid
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C43H65N11O14S2
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1
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| 1 |
EC50 = 0.35 nM
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CP0559401
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3-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-4-[(2S)-2-(methoxymethyl)pyrrolidine-1-carbonyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-10-yl]propanamide
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C36H54N8O10S2
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1
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| 1 |
EC50 = 0.44 nM
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CP0380610
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)-methylamino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C44H68N12O12S2
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2
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| 1 |
EC50 = 0.47 nM
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| 2 |
Ki = 1.32 nM
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CP0475798
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3-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-4-(pyrrolidine-1-carbonyl)-1,2-dithia-5,8,11,14,17-pentazacycloicos-10-yl]propanamide
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C34H50N8O9S2
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1
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| 1 |
EC50 = 0.51 nM
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CP0454919
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-N-methylpyrrolidine-2-carboxamide
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C44H68N12O12S2
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2
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| 1 |
EC50 = 0.52 nM
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| 2 |
Ki = 0.97 nM
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CP0437088
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(2S)-N-[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C47H74N14O12S2
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1
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| 1 |
EC50 = 0.53 nM
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CP0401891
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(2S)-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)-methylamino]-4-methyl-1-oxopentan-2-yl]-N-methylpyrrolidine-2-carboxamide
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C45H69N11O12S2
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2
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| 1 |
EC50 = 0.59 nM
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| 2 |
Ki = 3.7 nM
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CP0519805
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3-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-4-[(2S)-2-(5-methyl-1,3,4-oxadiazol-2-yl)pyrrolidine-1-carbonyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-10-yl]propanamide
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C37H52N10O10S2
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1
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| 1 |
EC50 = 0.6 nM
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CP0541176
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3-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-4-[(2S)-2-methylpyrrolidine-1-carbonyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-10-yl]propanamide
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C35H52N8O9S2
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1
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| 1 |
EC50 = 0.6 nM
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CP0519809
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3-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-4-[(2S)-2-(anilinomethyl)pyrrolidine-1-carbonyl]-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-10-yl]propanamide
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C41H57N9O9S2
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1
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| 1 |
EC50 = 0.77 nM
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CP0412902
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-10-(2-methylpropyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C44H68N10O11S2
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1
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| 1 |
EC50 = 0.78 nM
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CP0545865
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3-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-4-[(2S)-2-pyridin-2-ylpyrrolidine-1-carbonyl]-1,2-dithia-5,8,11,14,17-pentazacycloicos-10-yl]propanamide
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C39H53N9O9S2
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1
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| 1 |
EC50 = 0.83 nM
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CP0458681
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-5-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C44H68N12O12S2
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2
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| 1 |
EC50 = 0.99 nM
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| 2 |
Ki = 1.05 nM
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CP0393833
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-10-[3-(diaminomethylideneamino)propyl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C44H69N13O11S2
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1
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| 1 |
EC50 = 1.2 nM
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CP0541177
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(2S)-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C35H51N9O10S2
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1
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| 1 |
EC50 = 1.3 nM
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CP0462679
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(2S)-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C44H67N11O12S2
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1
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| 1 |
EC50 = 1.4 nM
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CP0493411
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C44H70N14O12S2
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1
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| 1 |
EC50 = 1.5 nM
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CP0405637
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(2S)-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C50H71N11O12S2
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1
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| 1 |
EC50 = 1.6 nM
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CP0437087
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(2S)-N-[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C47H73N11O12S2
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1
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| 1 |
EC50 = 1.6 nM
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CP0407995
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(2S)-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-methyl-N-(3-methylbutyl)pyrrolidine-2-carboxamide
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C41H63N9O10S2
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1
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| 1 |
EC50 = 1.8 nM
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CP0407996
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(2S)-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C41H62N10O11S2
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1
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| 1 |
EC50 = 1.8 nM
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CP0399539
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(2S)-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-5-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)-methylamino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C45H69N11O12S2
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1
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| 1 |
EC50 = 2.41 nM
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CP0462678
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-N-[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C44H69N11O12S2
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1
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| 1 |
EC50 = 3.4 nM
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CP0493407
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-(2-methylpropyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C40H67N11O11S2
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1
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| 1 |
EC50 = 3.6 nM
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CP0410319
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3-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-4-[(2S)-2-(4-methyl-1,4-diazepane-1-carbonyl)pyrrolidine-1-carbonyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-10-yl]propanamide
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C41H62N10O10S2
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1
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| 1 |
EC50 = 3.6 nM
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CP0380606
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-5-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-methylpyrrolidine-2-carboxamide
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C45H69N11O12S2
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1
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| 1 |
EC50 = 4.23 nM
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CP0437085
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-13-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C40H59N11O12S2
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1
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| 1 |
EC50 = 4.4 nM
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CP0041007
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1-(1-(4-(1-acetylpiperidin-4-yloxy)-2-methoxybenzoyl)piperidin-4-yl)-1H-benzo[d][1,3]oxazin-2(4H)-one
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C28H33N3O6
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1
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| 1 |
EC50 = 4.6 nM
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CP0454918
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-19-(methylamino)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C44H68N12O12S2
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2
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| 1 |
EC50 = 4.77 nM
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| 2 |
Ki = 5.47 nM
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CP0437081
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3-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-4-[(2S)-2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-10-yl]propanoic acid
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C43H64N10O13S2
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1
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| 1 |
EC50 = 5.1 nM
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CP0559454
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3-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-4-[(2R)-2-(2-phenylethyl)pyrrolidine-1-carbonyl]-1,2-dithia-5,8,11,14,17-pentazacycloicos-10-yl]propanamide
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C42H58N8O9S2
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1
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| 1 |
EC50 = 5.2 nM
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CP0519807
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(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
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C30H44N8O9S2
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1
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| 1 |
EC50 = 5.4 nM
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CP0459451
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)-methylamino]-4-methyl-1-oxopentan-2-yl]-N-methylpyrrolidine-2-carboxamide
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C45H70N12O12S2
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2
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| 1 |
EC50 = 5.52 nM
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| 2 |
Ki = 10.71 nM
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CP0408000
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3-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-4-[(2S)-2-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)pyrrolidine-1-carbonyl]-1,2-dithia-5,8,11,14,17-pentazacycloicos-10-yl]propanamide
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C44H66N10O10S2
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1
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| 1 |
EC50 = 6.8 nM
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CP0445465
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-5,17-dimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C45H70N12O12S2
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1
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| 1 |
EC50 = 6.98 nM
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CP0386484
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-5,17-dimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C45H69N11O12S2
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1
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| 1 |
EC50 = 7.98 nM
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CP0386696
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N-(2-pyridin-2-ylpyrazol-3-yl)-4-(trifluoromethyl)benzenesulfonamide
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C15H11F3N4O2S
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2
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| 1 |
EC50 = 8 nM
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| 2 |
IC50 > 10000 nM
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CP0192572
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AVP
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C46H65N15O12S2
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3
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| 1 |
EC50 = 8.3 nM
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| 2 |
Ki = 1.65 nM
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| 3 |
Ki = 1.7 nM
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CP0437083
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(4S)-5-amino-4-[[(2S)-2-[[(2S)-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-5-oxopentanoic acid
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C46H69N11O14S2
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1
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| 1 |
EC50 = 9.5 nM
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CP0401890
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-5-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)-methylamino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C45H70N12O12S2
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2
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| 1 |
EC50 = 10.79 nM
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| 2 |
Ki = 34.26 nM
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CP0469896
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-7-(hydroxymethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C42H64N10O12S2
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1
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| 1 |
EC50 = 12 nM
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CP0474278
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S,5S,8S,11S,14S)-11-(2-amino-2-oxoethyl)-8-(3-amino-3-oxopropyl)-5-[(2S)-butan-2-yl]-2-[(4-hydroxyphenyl)methyl]-3,6,9,12,16,20-hexaoxo-1,4,7,10,13,17-hexazacycloicosane-14-carbonyl]pyrrolidine-2-carboxamide
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C44H66N12O13
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1
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| 1 |
EC50 = 13 nM
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CP0403183
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-14-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C44H68N12O12S2
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2
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| 1 |
EC50 = 14.74 nM
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| 2 |
Ki = 112.88 nM
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CP0558439
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-5-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-N-methylpyrrolidine-2-carboxamide
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C45H70N12O12S2
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2
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| 1 |
EC50 = 15.57 nM
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| 2 |
Ki = 68.54 nM
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CP0380837
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N-[2-(4-methylpyridin-2-yl)pyrazol-3-yl]-4-(trifluoromethyl)benzenesulfonamide
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C16H13F3N4O2S
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1
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| 1 |
EC50 = 17 nM
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CP0393835
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-7-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C42H64N10O11S2
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1
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| 1 |
EC50 = 17 nM
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CP0393939
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4-chloro-N-(2-pyridin-2-ylpyrazol-3-yl)benzenesulfonamide
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C14H11ClN4O2S
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2
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| 1 |
EC50 = 19 nM
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| 2 |
IC50 > 10000 nM
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CP0546223
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4-chloro-2-fluoro-N-(2-pyridin-2-ylpyrazol-3-yl)benzenesulfonamide
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C14H10ClFN4O2S
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1
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| 1 |
EC50 = 19 nM
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CP0437080
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-benzyl-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C47H66N10O11S2
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1
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| 1 |
EC50 = 22 nM
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CP0380602
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-17-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C44H68N12O12S2
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2
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| 1 |
EC50 = 23.93 nM
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| 2 |
Ki = 6.76 nM
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CP0458680
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-8-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C44H68N12O12S2
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2
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| 1 |
EC50 = 25.99 nM
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| 2 |
Ki = 31.46 nM
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CP0562541
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3-[(7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-10-yl]propanamide
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C29H43N7O8S2
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1
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| 1 |
EC50 = 28 nM
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CP0078819
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(2S)-N-{2-Methyl-4-[(1-methyl-4,10-dihydropyrazolo[3,4-b]-[1,5]benzodiazepin-5(1H)-yl)carbonyl]benzyl}-2-[(4-methyl-1,4-diazepan-1-yl)carbonothioyl]pyrrolidine-1-carboxamide
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C32H40N8O2S
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2
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| 1 |
EC50 = 33 nM
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| 2 |
Ki = 147 nM
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CP0387328
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(5R,8S,11S,14S,17S)-8-(2-amino-2-oxoethyl)-11-(3-amino-3-oxopropyl)-14-[(2S)-butan-2-yl]-17-[(4-hydroxyphenyl)methyl]-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carbonyl]pyrrolidine-2-carboxamide
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C51H73N11O12S2
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1
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| 1 |
EC50 = 34 nM
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CP0405638
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-(hydroxymethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C40H59N11O13S2
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1
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| 1 |
EC50 = 40 nM
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CP0546222
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N-(2-pyridin-2-ylpyrazol-3-yl)-4-(trifluoromethylsulfanyl)benzenesulfonamide
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C15H11F3N4O2S2
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1
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| 1 |
EC50 = 47 nM
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CP0260717
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2-phenyl-N-[4-(2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]benzamide
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C30H26N2O2
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2
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| 1 |
EC50 = 63 nM
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| 2 |
Ki = 109 nM
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CP0558611
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3-[(4R,7S,10S,13S,16S)-4-[(2S)-2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-7-yl]propanoic acid
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C44H66N10O13S2
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1
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| 1 |
EC50 = 89 nM
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CP0476263
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-2,21-dithia-5,8,11,14,17-pentazabicyclo[21.2.2]heptacosa-1(25),23,26-triene-4-carbonyl]pyrrolidine-2-carboxamide
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C50H71N11O12S2
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1
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| 1 |
EC50 = 109 nM
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CP0083253
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(5H,11H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-yl)-[2-chloro-4-(3-methyl-pyrazol-1-yl)-phenyl]-methanone
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C23H19ClN4O
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3
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| 1 |
EC50 = 125 nM
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| 2 |
IC50 = 353 nM
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| 3 |
Ki = 199 nM
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CP0403182
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-5-methyl-19-(methylamino)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C45H70N12O12S2
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2
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| 1 |
EC50 = 174.86 nM
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| 2 |
Ki = 98.63 nM
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CP0444344
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3-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-4-[(2S)-2-(phenoxymethyl)pyrrolidine-1-carbonyl]-1,2-dithia-5,8,11,14,17-pentazacycloicos-10-yl]propanamide
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C41H56N8O10S2
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1
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| 1 |
EC50 = 194 nM
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CP0399543
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-5,14-dimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C45H70N12O12S2
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1
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| 1 |
EC50 = 283.01 nM
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CP0386760
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(5R,8S,11S,14S,17S)-8-(2-amino-2-oxoethyl)-11-(3-amino-3-oxopropyl)-14-[(2S)-butan-2-yl]-17-[(4-hydroxyphenyl)methyl]-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carbonyl]pyrrolidine-2-carboxamide
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C51H73N11O12S2
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1
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| 1 |
EC50 = 294 nM
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CP0455924
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N-[2-(4-methyl-1,3-thiazol-2-yl)pyrazol-3-yl]-4-(trifluoromethyl)benzenesulfonamide
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C14H11F3N4O2S2
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1
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| 1 |
EC50 = 520 nM
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CP0553463
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N-(2-pyridin-2-ylpyrazol-3-yl)-4-(trifluoromethylsulfonyl)benzenesulfonamide
Show/Hide
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C15H11F3N4O4S2
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1
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| 1 |
EC50 = 753 nM
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CP0433008
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N-[2-(3-cyclopropyl-1,2,4-thiadiazol-5-yl)pyrazol-3-yl]-4-ethylbenzenesulfonamide
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C16H17N5O2S2
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1
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| 1 |
EC50 = 1570 nM
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CP0537547
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4-(trifluoromethyl)-N-[2-[5-(trifluoromethyl)pyrimidin-2-yl]pyrazol-3-yl]benzenesulfonamide
Show/Hide
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C15H9F6N5O2S
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1
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| 1 |
EC50 = 1570 nM
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CP0498637
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4-chloro-N-[2-(4-fluorophenyl)pyrazol-3-yl]benzenesulfonamide
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C15H11ClFN3O2S
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1
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| 1 |
EC50 = 2460 nM
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CP0430562
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(5R,8S,11S,14S,17S)-8-(2-amino-2-oxoethyl)-11-(3-amino-3-oxopropyl)-14-[(2S)-butan-2-yl]-17-[(4-hydroxyphenyl)methyl]-7,10,13,16,19-pentaoxo-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.4.0]octacosa-1(28),24,26-triene-5-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C51H74N14O12S2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 = 1724 nM
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CP0387238
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-10-(3-amino-3-oxopropyl)-7-benzyl-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C48H68N10O11S2
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1
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| 1 |
EC50 > 100 nM
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CP0387239
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-7-[3-(diaminomethylideneamino)propyl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C45H71N13O11S2
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1
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| 1 |
EC50 > 100 nM
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CP0387245
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3-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-4-[(2S)-2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-13-yl]propanoic acid
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C42H61N11O14S2
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1
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| 1 |
EC50 > 100 nM
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CP0387246
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-7-(2-methylpropyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C45H70N10O11S2
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1
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| 1 |
EC50 > 100 nM
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CP0458268
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-(hydroxymethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C37H61N11O12S2
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1
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| 1 |
EC50 > 100 nM
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CP0459939
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[3-(diaminomethylideneamino)propyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C40H68N14O11S2
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1
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| 1 |
EC50 > 100 nM
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CP0493477
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3-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-4-[(2S)-2-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-16-yl]propanoic acid
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C39H63N11O13S2
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1
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| 1 |
EC50 > 100 nM
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CP0493479
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[3-(diaminomethylideneamino)propyl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C43H66N14O12S2
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1
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| 1 |
EC50 > 100 nM
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CP0513590
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C37H61N11O11S2
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1
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| 1 |
EC50 > 100 nM
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CP0380605
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-5,14-dimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C45H69N11O12S2
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1
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| 1 |
EC50 > 1000 nM
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CP0403184
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(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-11-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
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C44H68N12O12S2
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2
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| 1 |
EC50 > 1000 nM
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| 2 |
Ki > 1007 nM
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CP0040044
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3-chloro-4-(10,11-dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-ylcarbonyl)-1-(5-fluoro-2-methylphenylcarboxamido)benzene
Show/Hide
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C27H21ClFN3O2
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1
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| 1 |
IC50 = 519 nM
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CP0373184
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N-[3-chloro-4-(9-oxo-8,11-dihydro-7H-pyrrolo[2,1-c][1,4]benzodiazepine-5-carbonyl)phenyl]-5-fluoro-2-methylbenzamide
Show/Hide
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C27H21ClFN3O3
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1
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| 1 |
IC50 = 1000 nM
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CP0392995
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2-(2-chloro-4-(5-fluoro-2-methylbenzamido)benzamido)benzoic acid
Show/Hide
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C22H16ClFN2O4
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1
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| 1 |
IC50 = 1000 nM
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CP0405268
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1-(2-(2-chloro-4-(5-fluoro-2-methylbenzamido)benzamido)benzyl)-1H-pyrrole-2-carboxylic acid
Show/Hide
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C27H21ClFN3O4
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1
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| 1 |
IC50 = 1000 nM
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CP0405269
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N-[3-chloro-4-(9-oxo-6a,11-dihydro-6H-pyrrolo[2,1-c][1,4]benzodiazepine-5-carbonyl)phenyl]-5-fluoro-2-methylbenzamide
Show/Hide
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C27H21ClFN3O3
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1
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| 1 |
IC50 = 1000 nM
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CP0386944
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N-(2-methylpyrazol-3-yl)-4-(trifluoromethyl)benzenesulfonamide
Show/Hide
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C11H10F3N3O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0386958
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4-chloro-N-(2-methylpyrazol-3-yl)benzenesulfonamide
Show/Hide
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C10H10ClN3O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0852136
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(R)-4-chloro-3-(5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2-oxoindolin-3-yl)-N-ethyl-N-(pyridin-3-ylmethyl)benzamide hydrochloride
Show/Hide
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C33H32Cl3N3O4
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1
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| 1 |
Ki = 0.5 nM
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CP0388756
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N-(cyclopropylmethyl)-3-methyl-N-(oxolan-2-ylmethyl)-4-phenylbenzamide
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C23H27NO2
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2
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| 1 |
Ki = 0.7943 nM
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| 2 |
Ki = 1.259 nM
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CP0127459
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N-(6-methoxypyridin-3-yl)-1,2-dimethyl-N-[[5-(2-methylphenyl)pyridin-2-yl]methyl]imidazole-4-sulfonamide
Show/Hide
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C24H25N5O3S
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2
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| 1 |
Ki = 0.7943 nM
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| 2 |
Ki = 12.59 nM
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CP0898453
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[Lys8(Alexa 488)]PVA
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C94H122Cl3N17O23S3
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1
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| 1 |
Ki = 1.04 nM
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CP0421138
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(LVA)2-{2-[3-(4-Hydroxy-phenyl)-2-(methyl-phenylacetyl-amino)-propionylamino]-3-phenyl-propionylamino}-pentanedioic acid 5-amide 1-[(2-carbamoyl-1-{1-[2-(1-carbamoyl-4-guanidino-butylcarbamoyl)-pyrrolidine-1-carbonyl]-4-guanidino-butylcarbamoyl}-ethyl)-amide]
Show/Hide
|
C53H74N16O11
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0392674
|
4HOPh(CH2)2CO-DTyr(Me)-Phe-Gln-Asn-Arg-Pro-Lys(5C-Rhm)-NH2
Show/Hide
|
C79H96N16O16
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0195952
|
(2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxyphenyl)-2-oxoindolin-3-yl)-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C30H32ClN3O8S
|
2
|
| 1 |
Ki = 1.514 nM
|
|
|
| 2 |
Ki = 25 nM
|
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CP0538864
|
2,5-dimethoxy-N-(6-methoxypyridin-3-yl)-N-[[5-(2-methylphenyl)pyridin-2-yl]methyl]benzenesulfonamide
Show/Hide
|
C27H27N3O5S
|
1
|
| 1 |
Ki = 1.585 nM
|
|
|
|
CP0392420
|
4HOPh(CH2)2CO-DTyr(Me)-Phe-Gln-Asn-Arg-Pro-Lys(5C-Flu)-NH2
Show/Hide
|
C75H86N14O18
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0873189
|
[Lys8(Alexa 546)]PVA
Show/Hide
|
C75H88N16O22S2
|
1
|
| 1 |
Ki = 1.95 nM
|
|
|
|
CP0266857
|
4-methoxy-N-(6-methoxypyridin-3-yl)-N-[[5-(2-methylphenyl)pyridin-2-yl]methyl]benzenesulfonamide
Show/Hide
|
C26H25N3O4S
|
2
|
| 1 |
Ki = 1.995 nM
|
|
|
| 2 |
Ki = 7.943 nM
|
|
|
|
CP0214389
|
N-[[5-[4-(2-oxo-4H-3,1-benzoxazin-1-yl)piperidine-1-carbonyl]-1-benzofuran-2-yl]methyl]-2-[2-oxo-5-(trifluoromethyl)pyridin-1-yl]acetamide
Show/Hide
|
C31H27F3N4O6
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0538865
|
2,4-dimethoxy-N-(6-methoxypyridin-3-yl)-N-[[5-(2-methylphenyl)pyridin-2-yl]methyl]benzenesulfonamide
Show/Hide
|
C27H27N3O5S
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0409447
|
(HO-LVA23)2-{2-[3-(4-Hydroxy-phenyl)-2-(methyl-4-Hydroxy-phenylacetyl-amino)-propionylamino]-3-phenyl-propionylamino}-pentanedioic acid 5-amide 1-[(2-carbamoyl-1-{1-[2-(1-carbamoyl-4-guanidino-butylcarbamoyl)-pyrrolidine-1-carbonyl]-4-guanidino-butylcarbamoyl}-ethyl)-amide]
Show/Hide
|
C53H74N16O12
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0387585
|
4-(2-chlorophenyl)-N-(cyclopropylmethyl)-N-(oxolan-2-ylmethyl)benzamide
Show/Hide
|
C22H24ClNO2
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0400046
|
N-(cyclopropylmethyl)-4-(4-fluoro-2-methylphenyl)-N-(oxolan-2-ylmethyl)benzamide
Show/Hide
|
C23H26FNO2
|
1
|
| 1 |
Ki = 3.162 nM
|
|
|
|
CP0037183
|
N-[[5-(2-chlorophenyl)pyridin-2-yl]methyl]-4-methoxy-N-(6-methoxypyridin-3-yl)benzenesulfonamide
Show/Hide
|
C25H22ClN3O4S
|
2
|
| 1 |
Ki = 3.162 nM
|
|
|
| 2 |
Ki = 12.59 nM
|
|
|
|
CP0534676
|
N-(6-methoxypyridin-3-yl)-N-[[5-(2-methylphenyl)pyridin-2-yl]methyl]pyridine-2-sulfonamide
Show/Hide
|
C24H22N4O3S
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0424652
|
(S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)-N-((S)-1-(2-amino-2-oxoethylamino)-5-guanidino-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C46H64N14O12S2
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0382048
|
N-(6-methoxypyridin-3-yl)-N-[[5-(2-methylphenyl)pyridin-2-yl]methyl]-4-methylsulfonylbenzenesulfonamide
Show/Hide
|
C26H25N3O5S2
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0453858
|
N-[[5-(2-fluorophenyl)pyridin-2-yl]methyl]-4-methoxy-N-(6-methoxypyridin-3-yl)benzenesulfonamide
Show/Hide
|
C25H22FN3O4S
|
2
|
| 1 |
Ki = 6.31 nM
|
|
|
| 2 |
Ki = 7.943 nM
|
|
|
|
CP0377821
|
N-[[5-(2-cyanophenyl)pyridin-2-yl]methyl]-4-methoxy-N-(6-methoxypyridin-3-yl)benzenesulfonamide
Show/Hide
|
C26H22N4O4S
|
2
|
| 1 |
Ki = 6.31 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0503440
|
(S)-1-((R)-5-chloro-3-(2-methoxy-4-((4-methylpiperazin-1-yl)methyl)phenyl)-1-(4-methoxyphenylsulfonyl)-2-oxoindolin-3-yl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C35H42ClN5O6S
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0457370
|
4-(3-chlorophenyl)-N-(cyclopropylmethyl)-N-(oxolan-2-ylmethyl)benzamide
Show/Hide
|
C22H24ClNO2
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0472057
|
N-(6-methoxypyridin-3-yl)-N-[[5-(2-methylphenyl)pyridin-2-yl]methyl]benzenesulfonamide
Show/Hide
|
C25H23N3O3S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0387122
|
1-[2-chloro-4-(3-methylpyrazol-1-yl)benzoyl]-3,4-dihydro-2H-1-benzazepin-5-one
Show/Hide
|
C21H18ClN3O2
|
1
|
| 1 |
Ki < 10 nM
|
|
|
|
CP0387539
|
(4-chlorophenyl)-(2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone
Show/Hide
|
C17H16ClNO
|
1
|
| 1 |
Ki < 10 nM
|
|
|
|
CP0394551
|
trimethyl-[4-(2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]azanium
Show/Hide
|
C20H25N2O+
|
1
|
| 1 |
Ki < 10 nM
|
|
|
|
CP0410534
|
(4-Amino-phenyl)-(2,3,4,5-tetrahydro-benzo[b]azepin-1-yl)-methanone
Show/Hide
|
C17H18N2O
|
1
|
| 1 |
Ki < 10 nM
|
|
|
|
CP0410985
|
azepan-1-yl-[2-chloro-4-(3-methylpyrazol-1-yl)phenyl]methanone
Show/Hide
|
C17H20ClN3O
|
1
|
| 1 |
Ki < 10 nM
|
|
|
|
CP0446342
|
1-[4-(3-methylpyrazol-1-yl)benzoyl]-3,4-dihydro-2H-1-benzazepin-5-one
Show/Hide
|
C21H19N3O2
|
1
|
| 1 |
Ki < 10 nM
|
|
|
|
CP0478547
|
(4-bromophenyl)-(2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone
Show/Hide
|
C17H16BrNO
|
1
|
| 1 |
Ki < 10 nM
|
|
|
|
CP0387540
|
(4-phenylphenyl)-(2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone
Show/Hide
|
C23H21NO
|
1
|
| 1 |
Ki = 10.4 nM
|
|
|
|
CP0037182
|
N-(6-methoxypyridin-3-yl)-1-methyl-N-[[5-(2-methylphenyl)pyridin-2-yl]methyl]imidazole-4-sulfonamide
Show/Hide
|
C23H23N5O3S
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0461514
|
N-(6-methoxypyridin-3-yl)-N-[[5-(2-methylphenyl)pyridin-2-yl]methyl]-3-methylsulfonylbenzenesulfonamide
Show/Hide
|
C26H25N3O5S2
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0502140
|
N-(6-methoxypyridin-3-yl)-2,4-dimethyl-N-[[5-(2-methylphenyl)pyridin-2-yl]methyl]-1,3-thiazole-5-sulfonamide
Show/Hide
|
C24H24N4O3S2
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0504336
|
N-(6-methoxypyridin-3-yl)-N-[[5-(2-methylphenyl)pyridin-2-yl]methyl]thiophene-2-sulfonamide
Show/Hide
|
C23H21N3O3S2
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0441987
|
2-((S)-2-((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-6-(3-aminopropanamido)hexanamido)acetic acid
Show/Hide
|
C50H71N11O13S2
|
1
|
| 1 |
Ki = 12.6 nM
|
|
|
|
CP0504737
|
N-ethyl-3-(3-fluoro-2-methylphenoxy)-N-(6-methoxypyridin-3-yl)azetidine-1-carboxamide
Show/Hide
|
C19H22FN3O3
|
1
|
| 1 |
Ki = 13.9 nM
|
|
|
|
CP0457371
|
N-benzyl-4-(4-fluoro-2-methylphenyl)-N-(oxolan-2-ylmethyl)benzamide
Show/Hide
|
C26H26FNO2
|
1
|
| 1 |
Ki = 15.85 nM
|
|
|
|
CP0381163
|
5-[2-Chloro-4-(3-methyl-1H-pyrazol-1-yl)benzoyl]-1-methyl-1,4,5,10-tetrahydro pyrazolo[3,4-b][1,5]benzodiazepine
Show/Hide
|
C22H19ClN6O
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0390719
|
(S)-1-((R)-5-chloro-3-(2-methoxy-5-(pyrrolidin-1-ylmethyl)phenyl)-1-(4-methoxyphenylsulfonyl)-2-oxoindolin-3-yl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C34H39ClN4O6S
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0390485
|
5-(3-(3-(4-fluoro-2-methylphenoxy)azetidin-1-yl)-5-methyl-4H-1,2,4-triazol-4-yl)-2-methoxypyridine
Show/Hide
|
C19H20FN5O2
|
1
|
| 1 |
Ki = 17.5 nM
|
|
|
|
CP0504738
|
5-(3-(3-(3-fluoro-2-methylphenoxy)azetidin-1-yl)-5-methyl-4H-1,2,4-triazol-4-yl)-2-methoxypyridine
Show/Hide
|
C19H20FN5O2
|
1
|
| 1 |
Ki = 19.7 nM
|
|
|
|
CP0486695
|
(S)-1-((R)-5-chloro-3-(2-methoxy-5-((4-methylpiperazin-1-yl)methyl)phenyl)-1-(4-methoxyphenylsulfonyl)-2-oxoindolin-3-yl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C35H42ClN5O6S
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0479071
|
2-((S)-2-((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-6-(2-aminobenzamido)hexanamido)acetic acid
Show/Hide
|
C54H71N11O13S2
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0441988
|
2-((S)-2-((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-6-(7-aminoheptanamido)hexanamido)acetic acid
Show/Hide
|
C54H79N11O13S2
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0868672
|
(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7,10-bis(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C45H62N14O12S2
|
1
|
| 1 |
Ki = 25.6 nM
|
|
|
|
CP0390163
|
1-Methyl-5-[3-methyl-4-(3-methyl-1H-pyrazol-1-yl)benzoyl]-1,4,5,10-tetrahydropyrazolo[3,4-b][1,5]benzodiazepine
Show/Hide
|
C23H22N6O
|
1
|
| 1 |
Ki = 27.8 nM
|
|
|
|
CP0497176
|
(2S,4Z)-N-[(2S)-2-hydroxy-2-phenylethyl]-4-(methoxyimino)-1-[(2'-methyl[1,1'-biphenyl]-4-yl)carbonyl]-2-pyrrolidinecarboxamide
Show/Hide
|
C28H29N3O4
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0456297
|
(S)-1-((R)-5-chloro-3-(2-methoxy-4-(pyrrolidin-1-ylmethyl)phenyl)-1-(4-methoxyphenylsulfonyl)-2-oxoindolin-3-yl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C34H39ClN4O6S
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0428981
|
5-(3-(3-(2-chloro-4-fluorophenoxy)azetidin-1-yl)-5-methyl-4H-1,2,4-triazol-4-yl)-2-methoxypyridine
Show/Hide
|
C18H17ClFN5O2
|
1
|
| 1 |
Ki = 28.4 nM
|
|
|
|
CP0503446
|
2-((S)-6-amino-2-((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)hexanamido)acetic acid
Show/Hide
|
C47H66N10O12S2
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0465012
|
(S)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxy-5-(pyrrolidin-1-ylmethyl)phenyl)-2-oxoindolin-3-yl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C35H41ClN4O7S
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0881072
|
triethylamine hemi(2-((S)-2-((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-6-(2-(6-amino-3-imino-4,5-disulfonato-3H-xanthen-9-yl)-5-((2,3,5,6-tetrafluorophenoxy)carbonyl)benzamido)hexanamido)acetate)
Show/Hide
|
C68H76Li2N12O22S4
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0490986
|
3-(3,5-difluoro-2-methylphenoxy)-N-ethyl-N-(6-methoxypyridin-3-yl)azetidine-1-carboxamide
Show/Hide
|
C19H21F2N3O3
|
1
|
| 1 |
Ki = 36.7 nM
|
|
|
|
CP0405719
|
(4-butylphenyl)-(2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone
Show/Hide
|
C21H25NO
|
1
|
| 1 |
Ki = 37.4 nM
|
|
|
|
CP0400045
|
N-benzyl-3-methyl-N-(oxolan-2-ylmethyl)-4-phenylbenzamide
Show/Hide
|
C26H27NO2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0382044
|
4-methoxy-N-(6-methoxypyridin-3-yl)-N-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]benzenesulfonamide
Show/Hide
|
C22H20N4O5S
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0538863
|
N-(6-methoxypyridin-3-yl)-N-[(4-phenyl-1,3-thiazol-2-yl)methyl]pyridine-2-sulfonamide
Show/Hide
|
C21H18N4O3S2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0463752
|
5-(3-(3-(3,5-difluoro-2-methylphenoxy)azetidin-1-yl)-5-methyl-4H-1,2,4-triazol-4-yl)-2-methoxypyridine
Show/Hide
|
C19H19F2N5O2
|
1
|
| 1 |
Ki = 41.4 nM
|
|
|
|
CP0456409
|
(2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxypyridin-3-yl)-2-oxoindolin-3-yl)-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C29H31ClN4O8S
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0496096
|
N-ethyl-3-(4-fluoro-2-methylphenoxy)-N-(6-methoxypyridin-3-yl)azetidine-1-carboxamide
Show/Hide
|
C19H22FN3O3
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0478219
|
(2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2,4-dimethoxypyrimidin-5-yl)-2-oxoindolin-3-yl)-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C29H32ClN5O9S
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0498370
|
(S)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxy-4-(pyrrolidin-1-ylmethyl)phenyl)-2-oxoindolin-3-yl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C35H41ClN4O7S
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0513955
|
3-(2-chloro-4-fluorophenoxy)-N-ethyl-N-(6-methoxypyridin-3-yl)azetidine-1-carboxamide
Show/Hide
|
C18H19ClFN3O3
|
1
|
| 1 |
Ki = 48.4 nM
|
|
|
|
CP0439670
|
(2S)-2-{[(2R)-1-{[(4S,7R,10S,13R,16S)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-10-methyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C44H61N13O11S2
|
1
|
| 1 |
Ki = 48.7 nM
|
|
|
|
CP0521469
|
N-(cyclopropylmethyl)-N-(oxolan-2-ylmethyl)-4-phenylbenzamide
Show/Hide
|
C22H25NO2
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0465011
|
(S)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(2-methoxypyridin-3-yl)-2-oxoindolin-3-yl)-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C29H31ClN4O7S
|
1
|
| 1 |
Ki = 62 nM
|
|
|
|
CP0444823
|
N-benzyl-4-(2-methoxyphenyl)-N-(oxolan-2-ylmethyl)benzamide
Show/Hide
|
C26H27NO3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0489424
|
N-(cyclopropylmethyl)-4-(2-methoxyphenyl)-N-(oxolan-2-ylmethyl)benzamide
Show/Hide
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C23H27NO3
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1
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| 1 |
Ki = 63.1 nM
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CP0382045
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N-(6-methoxypyridin-3-yl)-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]pyridine-2-sulfonamide
Show/Hide
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C20H17N5O4S
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1
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| 1 |
Ki = 63.1 nM
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CP0417763
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N-(4-methoxyphenyl)-N-[(2-phenyl-1,3-thiazol-4-yl)methyl]pyridine-2-sulfonamide
Show/Hide
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C22H19N3O3S2
|
1
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| 1 |
Ki = 63.1 nM
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CP0430363
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3-(2-chloro-4-fluorophenoxy)-N-(6-methoxypyridin-3-yl)-N-methylazetidine-1-carboxamide
Show/Hide
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C17H17ClFN3O3
|
1
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| 1 |
Ki = 67.2 nM
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CP0388755
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N-benzyl-N-(oxolan-2-ylmethyl)-6-[2-(trifluoromethyl)phenyl]pyridine-3-carboxamide
Show/Hide
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C25H23F3N2O2
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1
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| 1 |
Ki = 79.43 nM
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CP0489423
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4-(4-chlorophenyl)-N-(cyclopropylmethyl)-N-(oxolan-2-ylmethyl)benzamide
Show/Hide
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C22H24ClNO2
|
1
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| 1 |
Ki = 79.43 nM
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CP0414114
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[4-(3-methylpyrazol-1-yl)phenyl]-(2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone
Show/Hide
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C21H21N3O
|
1
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| 1 |
Ki = 84 nM
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CP0462769
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(R)-5-chloro-3-(2-methoxy-5-((4-methylpiperazin-1-yl)methyl)phenyl)-1-(4-methoxyphenylsulfonyl)-3-((S)-2-(oxazol-2-yl)pyrrolidin-1-yl)indolin-2-one
Show/Hide
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C35H38ClN5O6S
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1
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| 1 |
Ki = 89 nM
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CP0911177
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-10-(1-hydroxyethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
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C45H63N13O12S2
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1
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| 1 |
Ki = 91 nM
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CP0454599
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(S)-(2-(hydroxymethyl)-4-(methoxyimino)pyrrolidin-1-yl)(2'-methylbiphenyl-4-yl)methanone
Show/Hide
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C20H22N2O3
|
1
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| 1 |
Ki = 95 nM
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CP0495010
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(2R)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4S,7R,10S,13R,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-10-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C47H67N13O11S2
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1
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| 1 |
Ki = 102 nM
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CP0405635
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(4-propylphenyl)-(2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone
Show/Hide
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C20H23NO
|
1
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| 1 |
Ki = 104 nM
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CP0376558
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5-[4-[(1,1'-Biphenyl-2-ylcarbonyl)amino]-3-methylbenzoyl]-1-methyl-1,4,5,10-tetrahydropyrazolo[3,4-b][1,5]benzodiazepine
Show/Hide
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C32H27N5O2
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1
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| 1 |
Ki = 111 nM
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CP0383095
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3-(4-fluoro-2-methylphenoxy)-N-(6-methoxypyridin-3-yl)-N-methylazetidine-1-carboxamide
Show/Hide
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C18H20FN3O3
|
1
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| 1 |
Ki = 112 nM
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CP0462768
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(R)-5-chloro-3-(5-((dimethylamino)methyl)-2-methoxyphenyl)-1-(4-methoxyphenylsulfonyl)-3-((S)-2-(oxazol-2-yl)pyrrolidin-1-yl)indolin-2-one
Show/Hide
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C32H33ClN4O6S
|
1
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| 1 |
Ki = 115 nM
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CP0489425
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N-(cyclopropylmethyl)-2-methyl-N-(oxolan-2-ylmethyl)-4-phenylbenzamide
Show/Hide
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C23H27NO2
|
1
|
| 1 |
Ki = 125.89 nM
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CP0388751
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4-methoxy-N-(6-methoxypyridin-3-yl)-N-[(5-phenylpyridin-2-yl)methyl]benzenesulfonamide
Show/Hide
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C25H23N3O4S
|
1
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| 1 |
Ki = 125.89 nM
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CP0844975
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-10,16-bis[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
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C50H65N13O12S2
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1
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| 1 |
Ki = 126 nM
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CP0907711
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-10-propyl-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
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C46H65N13O11S2
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1
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| 1 |
Ki = 131 nM
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CP0390720
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(R)-5-chloro-3-(2-methoxy-5-((methylamino)methyl)phenyl)-1-(4-methoxyphenylsulfonyl)-3-((S)-2-(oxazol-2-yl)pyrrolidin-1-yl)indolin-2-one
Show/Hide
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C31H31ClN4O6S
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1
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| 1 |
Ki = 135 nM
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CP0372643
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-10-propan-2-yl-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
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C46H65N13O11S2
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1
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| 1 |
Ki = 136 nM
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CP0844971
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-10-butyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
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C47H67N13O11S2
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1
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| 1 |
Ki = 143 nM
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CP0414112
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(4-pyridin-3-ylphenyl)-(2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone
Show/Hide
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C22H20N2O
|
1
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| 1 |
Ki = 150 nM
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CP0428979
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3-(3-fluoro-2-methylphenoxy)-N-(6-methoxypyridin-3-yl)-N-methylazetidine-1-carboxamide
Show/Hide
|
C18H20FN3O3
|
1
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| 1 |
Ki = 159 nM
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|
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CP0844972
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(2S)-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]-2-{[(2R)-1-{[(4S,7R,13R,16S)-10,13-dibenzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}pentanamide
Show/Hide
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C50H65N13O11S2
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1
|
| 1 |
Ki = 164 nM
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|
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CP0482229
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(R)-5-chloro-3-(2-methoxy-5-(pyrrolidin-1-ylmethyl)phenyl)-1-(4-methoxyphenylsulfonyl)-3-((S)-2-(oxazol-2-yl)pyrrolidin-1-yl)indolin-2-one
Show/Hide
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C34H35ClN4O6S
|
1
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| 1 |
Ki = 170 nM
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CP0479072
|
2-((2S)-6-amino-2-((2S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-19-hydroxy-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)hexanamido)acetic acid
Show/Hide
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C47H66N10O13S2
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1
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| 1 |
Ki = 179 nM
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CP0381621
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1-ethyl-2-[(1E,3E,5Z)-5-[1-ethyl-3-methyl-3-[4-oxo-4-[2-[4-[[[4-oxo-4-[[1-[4-[(2-phenylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]butanoyl]amino]methyl]triazol-1-yl]ethylamino]butyl]-5-sulfoindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-5-sulfonate
Show/Hide
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C71H76N10O11S2
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1
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| 1 |
Ki = 184 nM
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CP0485350
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N-(cyclopropylmethyl)-N-(oxolan-2-ylmethyl)-4-[3-(trifluoromethyl)pyridin-2-yl]benzamide
Show/Hide
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C22H23F3N2O2
|
1
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| 1 |
Ki = 199.53 nM
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CP0453857
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N-(4-methoxyphenyl)-N-[(2-oxo-1-azatricyclo[7.3.1.05,13]trideca-3,5(13),6,8-tetraen-3-yl)methyl]benzenesulfonamide
Show/Hide
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C26H24N2O4S
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1
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| 1 |
Ki = 199.53 nM
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CP0844981
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-10-(hydroxymethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C44H61N13O12S2
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1
|
| 1 |
Ki = 206 nM
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|
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CP0495187
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2-((S)-2-((S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-6-(11-aminoundecanamido)hexanamido)acetic acid
Show/Hide
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C58H87N11O13S2
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1
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| 1 |
Ki = 210 nM
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CP0425070
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(2S)-2-{[(2R)-1-{[(4S,7R,10S,13R,16S)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-10-(2-methylpropyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C47H67N13O11S2
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1
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| 1 |
Ki = 211 nM
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|
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CP0897831
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-10-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C52H66N14O11S2
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1
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| 1 |
Ki = 223 nM
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CP0918735
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-10-ethyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C45H63N13O11S2
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1
|
| 1 |
Ki = 224 nM
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CP0401519
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3-(3,5-difluoro-2-methylphenoxy)-N-(6-methoxypyridin-3-yl)-N-methylazetidine-1-carboxamide
Show/Hide
|
C18H19F2N3O3
|
1
|
| 1 |
Ki = 237 nM
|
|
|
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CP0405364
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-10-(cyclohexylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
|
C50H71N13O11S2
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1
|
| 1 |
Ki = 240 nM
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|
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CP0373549
|
(2S)-N-{2-Methyl-4-[(4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)-piperidin-1-yl)carbonyl]benzyl}-2-[(4-methyl-1,4-diazepan-1-yl)-carbonothioyl]pyrrolidine-1-carboxamide
Show/Hide
|
C34H44N6O4S
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1
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| 1 |
Ki = 245 nM
|
|
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CP0434806
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(2S)-1-(biphenylcarbonyl)-N-(2-hydroxy-2-phenylethyl)-4-(methoxyimino)pyrrolidine-2-carboxamide
Show/Hide
|
C27H27N3O4
|
1
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| 1 |
Ki = 260 nM
|
|
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CP0465013
|
(2S,4R)-1-((R)-5-chloro-1-(2,4-dimethoxyphenylsulfonyl)-3-(3-methoxypyrazin-2-yl)-2-oxoindolin-3-yl)-4-hydroxy-N,N-dimethylpyrrolidine-2-carboxamide
Show/Hide
|
C28H30ClN5O8S
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1
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| 1 |
Ki = 271 nM
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|
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CP0376810
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4-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]-3-[2-[2-[2-[2-[4-[[[4-[[1-[4-[(2-methylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]-4-oxobutanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethylsulfamoyl]benzenesulfonate
Show/Hide
|
C67H78N10O13S2
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1
|
| 1 |
Ki = 307 nM
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CP0509034
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N-(cyclopropylmethyl)-N-(oxolan-2-ylmethyl)-6-[2-(trifluoromethyl)phenyl]pyridine-3-carboxamide
Show/Hide
|
C22H23F3N2O2
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1
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| 1 |
Ki = 316.23 nM
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|
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CP0401557
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N-(cyclohexylmethyl)-1-[2-[1-(2,4-dimethoxyphenyl)sulfonyl-3,4-dihydro-2H-quinolin-2-yl]ethylsulfonyl]piperidin-4-amine
Show/Hide
|
C31H45N3O6S2
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1
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| 1 |
Ki = 316.23 nM
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|
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CP0465004
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1-(1,4-diazepan-1-yl)-2-(5-methoxy-1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2-methyl-1H-indol-3-yl)ethanone
Show/Hide
|
C26H33N3O5S
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1
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| 1 |
Ki = 320 nM
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CP0451057
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N-[3-chloro-4-(2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]-3-methylpyrazole-1-carboxamide
Show/Hide
|
C22H21ClN4O2
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1
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| 1 |
Ki = 325 nM
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|
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CP0418413
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-aminopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
Show/Hide
|
C46H66N14O11S2
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1
|
| 1 |
Ki = 326 nM
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CP0476644
|
(4-pyrimidin-2-ylphenyl)-(2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone
Show/Hide
|
C21H19N3O
|
1
|
| 1 |
Ki = 340 nM
|
|
|
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CP0899715
|
(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-10-(thiophen-2-ylmethyl)-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C48H63N13O11S3
|
1
|
| 1 |
Ki = 369 nM
|
|
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CP0452018
|
N-[(2R)-3-(4-chlorophenyl)-1-[[4-(dimethylamino)cyclohexyl]amino]-1-oxopropan-2-yl]-1-(4-fluorophenyl)cyclopropane-1-carboxamide
Show/Hide
|
C27H33ClFN3O2
|
1
|
| 1 |
Ki = 380.19 nM
|
|
|
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CP0405634
|
(4-iodophenyl)-(2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone
Show/Hide
|
C17H16INO
|
1
|
| 1 |
Ki = 396 nM
|
|
|
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CP0870976
|
(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-10-(2-aminoethyl)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C45H64N14O11S2
|
1
|
| 1 |
Ki = 482 nM
|
|
|
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CP0376808
|
2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]-5-[2-[2-[2-[2-[4-[[[4-[[1-[4-[(2-methylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]-4-oxobutanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethylsulfamoyl]benzenesulfonate
Show/Hide
|
C67H78N10O13S2
|
1
|
| 1 |
Ki = 495 nM
|
|
|
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CP0456966
|
(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
|
C43H59N13O11S2
|
1
|
| 1 |
Ki = 556 nM
|
|
|
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CP0388754
|
N-(cyclopropylmethyl)-4-(2-methylsulfonylphenyl)-N-(oxolan-2-ylmethyl)benzamide
Show/Hide
|
C23H27NO4S
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0457372
|
N-benzyl-2-methyl-N-(oxolan-2-ylmethyl)-4-phenylbenzamide
Show/Hide
|
C26H27NO2
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
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CP0853921
|
3-[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-4-{[(2R)-2-{[(1S)-1-[(carbamoylmethyl)carbamoyl]-4-[(diaminomethylidene)amino]butyl]carbamoyl}pyrrolidin-1-yl]carbonyl}-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-10-yl]propanoic acid
Show/Hide
|
C46H63N13O13S2
|
1
|
| 1 |
Ki = 664 nM
|
|
|
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CP0376809
|
2-(3-hydroxy-6-oxoxanthen-9-yl)-5-[2-[2-[2-[2-[4-[[[4-oxo-4-[[1-[4-[(2-phenylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]butanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethylcarbamothioylamino]benzoic acid
Show/Hide
|
C66H63N9O12S
|
1
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| 1 |
Ki = 665 nM
|
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CP0410987
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(5-hydroxy-2,3,4,5-tetrahydro-1-benzazepin-1-yl)-[4-(3-methylpyrazol-1-yl)phenyl]methanone
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C21H21N3O2
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1
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| 1 |
Ki = 686 nM
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CP0387119
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[2-chloro-4-(3-methylpyrazol-1-yl)phenyl]-(5-hydroxy-2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone
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C21H20ClN3O2
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1
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| 1 |
Ki = 800 nM
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CP0392288
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1-ethyl-2-[(1E,3E,5E)-5-[1-ethyl-3-methyl-3-[4-oxo-4-[2-[2-[2-[2-[4-[[[4-oxo-4-[[1-[4-[(2-phenylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]butanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethylamino]butyl]-5-sulfoindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-5-sulfonate
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C77H88N10O14S2
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1
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| 1 |
Ki = 808 nM
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CP0381215
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(2S)-N-[2-Methyl-4-(2,3,4,5-tetrahydro-1H-1-benzazepin-1-ylcarbonyl)benzyl]-2-[(4-methyl-1,4-diazepan-1-yl)carbonothioyl]-pyrrolidine-1-carboxamide
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C30H40N6O2S
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1
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| 1 |
Ki = 844 nM
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CP0869924
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triethylamine hemi(2-((2S)-2-((2S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-19-hydroxy-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-6-(2-(6-amino-3-imino-4,5-disulfonato-3H-xanthen-9-yl)-5-((2,3,5,6-tetrafluorophenoxy)carbonyl)benzamido)hexanamido)acetate)
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C68H76Li2N12O23S4
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1
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| 1 |
Ki = 963 nM
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CP0387587
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N-benzyl-4-(2-cyanophenyl)-N-(oxolan-2-ylmethyl)benzamide
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C26H24N2O2
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1
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| 1 |
Ki = 1000 nM
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CP0434297
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N-benzyl-N-(oxolan-2-ylmethyl)-4-[3-(trifluoromethyl)pyridin-2-yl]benzamide
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C25H23F3N2O2
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1
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| 1 |
Ki = 1000 nM
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CP0844973
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-10-(aminomethyl)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
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C44H62N14O11S2
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1
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| 1 |
Ki = 1033 nM
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CP0432651
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(2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-10-[3-(diaminomethylideneamino)propyl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
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C47H68N16O11S2
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1
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| 1 |
Ki = 1083 nM
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CP0410988
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[5-(dimethylamino)-2,3,4,5-tetrahydro-1-benzazepin-1-yl]-[4-(3-methylpyrazol-1-yl)phenyl]methanone
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C23H26N4O
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1
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| 1 |
Ki = 1333 nM
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CP0875035
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-13-benzyl-7-(carbamoylmethyl)-10-{4-[(diaminomethylidene)amino]butyl}-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
Show/Hide
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C48H70N16O11S2
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1
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| 1 |
Ki = 1364 nM
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CP0845005
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(2S)-2-{[(2R)-1-{[(4S,7R,13R,16S)-10-(4-aminobutyl)-13-benzyl-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}pyrrolidin-2-yl]formamido}-N-(carbamoylmethyl)-5-[(diaminomethylidene)amino]pentanamide
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C47H68N14O11S2
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1
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| 1 |
Ki = 1429 nM
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CP0434296
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4-(2-cyanophenyl)-N-(cyclopropylmethyl)-N-(oxolan-2-ylmethyl)benzamide
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C23H24N2O2
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1
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| 1 |
Ki = 1995.26 nM
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CP0417955
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(2S)-N-[2-Methyl-4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)benzyl]-2-[(4-methyl-1,4-diazepan-1-yl)carbonothioyl]pyrrolidine-1-carboxamide
Show/Hide
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C33H40N6O2S
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1
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| 1 |
Ki = 2500 nM
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CP0436858
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N-cyclopentyl-4-methoxy-N-[[2-[4-[(2-methylpropylamino)methyl]phenyl]-1,3-thiazol-4-yl]methyl]benzenesulfonamide
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C27H35N3O3S2
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1
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| 1 |
Ki = 2511.89 nM
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CP0396674
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N-(cyclopropylmethyl)-N-(oxolan-2-ylmethyl)-6-phenylpyridine-3-carboxamide
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C21H24N2O2
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1
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| 1 |
Ki = 3162.28 nM
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CP0457373
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N-benzyl-N-(oxolan-2-ylmethyl)-6-phenylpyridine-3-carboxamide
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C24H24N2O2
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1
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| 1 |
Ki = 3162.28 nM
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CP0494303
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2-((2S)-2-((2S)-1-((4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-13-benzyl-19-hydroxy-16-(4-hydroxybenzyl)-10-isobutyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamido)-6-(11-aminoundecanamido)hexanamido)acetic acid
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C58H87N11O14S2
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1
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| 1 |
Ki = 3742 nM
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CP0373513
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N-cyclopentyl-N-[[2-[4-(diethylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]-4-methoxybenzenesulfonamide
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C27H35N3O3S2
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1
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| 1 |
Ki = 3981.07 nM
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CP0503557
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N-[[2-[4-(butylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]-N-cyclopentyl-4-methoxybenzenesulfonamide
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C27H35N3O3S2
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1
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| 1 |
Ki = 5011.87 nM
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CP0396675
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N-(cyclopropylmethyl)-4-(2-methoxy-5-methylphenyl)-N-(oxolan-2-ylmethyl)benzamide
Show/Hide
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C24H29NO3
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1
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| 1 |
Ki = 6309.57 nM
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CP0475084
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N-benzyl-4-(2-methoxy-5-methylphenyl)-N-(oxolan-2-ylmethyl)benzamide
Show/Hide
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C27H29NO3
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1
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| 1 |
Ki = 6309.57 nM
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CP0468260
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N-cyclopentyl-4-methoxy-N-[[2-[4-(propylaminomethyl)phenyl]-1,3-thiazol-4-yl]methyl]benzenesulfonamide
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C26H33N3O3S2
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1
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| 1 |
Ki = 6309.57 nM
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CP0468261
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N-[[2-[4-[(cyclohexylmethylamino)methyl]phenyl]-1,3-thiazol-4-yl]methyl]-N-cyclopentyl-4-methoxybenzenesulfonamide
Show/Hide
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C30H39N3O3S2
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1
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| 1 |
Ki = 6309.57 nM
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CP0372122
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CHEMBL1774023
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C24H27Cl2N3O2
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1
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| 1 |
Ki >= 10000 nM
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CP0378123
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CHEMBL1774024
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C26H29Cl2N3O2
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1
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| 1 |
Ki >= 10000 nM
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CP0441841
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(1,4-diazepan-1-yl)(5-methoxy-1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2-methyl-1H-indol-3-yl)methanone
Show/Hide
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C25H31N3O5S
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1
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| 1 |
Ki > 10000 nM
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CP0376807
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2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]-5-[2-[2-[2-[2-[4-[[[4-oxo-4-[[1-[4-[(2-phenylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]butanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethylsulfamoyl]benzenesulfonate
Show/Hide
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C72H80N10O13S2
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1
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| 1 |
Ki > 10000 nM
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CP0452234
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4-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]-3-[2-[2-[2-[2-[4-[[[4-oxo-4-[[1-[4-[(2-phenylbenzoyl)amino]benzoyl]-2,3,4,5-tetrahydro-1-benzazepin-5-yl]amino]butanoyl]amino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethylsulfamoyl]benzenesulfonate
Show/Hide
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C72H80N10O13S2
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1
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| 1 |
Ki > 10000 nM
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CP0503556
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N-cyclopentyl-N-[[2-[4-[(furan-3-ylmethylamino)methyl]phenyl]-1,3-thiazol-4-yl]methyl]-4-methoxybenzenesulfonamide
Show/Hide
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C28H31N3O4S2
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1
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| 1 |
Ki = 19952.62 nM
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CP0478455
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N-cyclopentyl-N-[[2-[4-[(2,2-dimethylpropylamino)methyl]phenyl]-1,3-thiazol-4-yl]methyl]-4-methoxybenzenesulfonamide
Show/Hide
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C28H37N3O3S2
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1
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| 1 |
Ki = 25118.86 nM
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CP0373642
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N-cyclopentyl-4-methoxy-N-[[2-[4-[[(4-methoxyphenyl)methylamino]methyl]phenyl]-1,3-thiazol-4-yl]methyl]benzenesulfonamide
Show/Hide
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C31H35N3O4S2
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1
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| 1 |
Ki = 50118.72 nM
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CP0375642
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N-[[2-methyl-4-(1-methyl-4,10-dihydropyrazolo[4,3-c][1,5]benzodiazepine-5-carbonyl)phenyl]methyl]pyrrolidine-1-carboxamide
Show/Hide
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C25H28N6O2
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1
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| 1 |
Ki > 1000 nM
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CP0394552
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[4-(dimethylamino)phenyl]-(2,3,4,5-tetrahydro-1-benzazepin-1-yl)methanone
Show/Hide
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C19H22N2O
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1
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| 1 |
Ki > 1000 nM
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CP0476806
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[2-chloro-4-(3-methylpyrazol-1-yl)phenyl]-[5-(dimethylamino)-2,3,4,5-tetrahydro-1-benzazepin-1-yl]methanone
Show/Hide
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C23H25ClN4O
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1
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| 1 |
Ki > 1000 nM
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CP0480397
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N-[4-(2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]acetamide
Show/Hide
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C19H20N2O2
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1
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| 1 |
Ki > 1000 nM
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CP0521470
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N-(cyclopropylmethyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-3-methyl-4-phenylbenzamide
Show/Hide
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C25H32N2O
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1
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| 1 |
Ki > 3162.28 nM
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CP0373551
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(2S)-N-[3-Chloro-4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)benzyl]-2-[(4-methyl-1,4-diazepan-1-yl)-carbonothioyl]pyrrolidine-1-carboxamide
Show/Hide
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C32H37ClN6O2S
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1
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| 1 |
Ki > 5000 nM
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CP0375639
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N-[[2-methyl-4-(1-methyl-4,10-dihydropyrazolo[4,3-c][1,5]benzodiazepine-5-carbonyl)phenyl]methyl]acetamide
Show/Hide
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C22H23N5O2
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1
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| 1 |
Ki > 5000 nM
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CP0375641
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1,1-dimethyl-3-[[2-methyl-4-(1-methyl-4,10-dihydropyrazolo[4,3-c][1,5]benzodiazepine-5-carbonyl)phenyl]methyl]urea
Show/Hide
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C23H26N6O2
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1
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| 1 |
Ki > 5000 nM
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