5-(2-cyclobutylethyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-[3-(1-methylcyclopropyl)propyl]-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-(4,4-difluorobutyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-(3-methylbutyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-(3-cyclopropylpropyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-(4-methylpentyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-[3-(1-chlorocyclopropyl)propyl]-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-(4-cyclopropylbutyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-(4,4,4-trifluorobutyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-(3-methylsulfanylpropyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

(2R,4R)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

5-(2-cyclopropylethyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

spiro[8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-3,1'-cyclopentane]-7-carboxylic acid

5-[3-(1-ethylcyclopropyl)propyl]-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-[3-(1-fluorocyclopropyl)propyl]-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-butyl-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-pentyl-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-(3-thiophen-2-ylpropyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

hydron;pyridine-3-carboxylate

8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

5-hexyl-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

(2R,3R,4S)-3-prop-2-enyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

5-ethyl-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-(3-cyclobutylpropyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

(+)-3-(1H-tetrazol-5-yl)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole

5-(2-thiophen-2-ylethyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

2-(difluoromethyl)-5-(3-(1-methylcyclopropyl)propyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-(3-cyclopropylpropyl)-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

(2R,3R,4S)-3-(2-methylpropyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

(2S,3R,4R)-3-(methylsulfanylmethyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

5-propyl-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-(2-cyclobutylethyl)-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-(3-methoxypropyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

(R)-3-(4-isopropylphenyl)-7-methyl-N-(1-phenoxypropan-2-yl)pyrazolo[1,5-a]pyrimidine-6-carboxamide

2-[difluoromethyl-5-pentyl-4H-pyrano[2,3-d]pyrimidine-4,7(3H)-dione

2-(difluoromethyl)-5-(2-(spiro[2.3]hexan-5-yl)ethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

(2S,3R,4R)-3-(methoxymethyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

(4aR,5R,5aR)-3-(1H-tetrazol-5-yl)-5-vinyl-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole

5-[(4-fluorophenyl)methyl]-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

(2S,3R,4R)-3-(ethoxymethyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

(+/-)-3-(1H-tetrazol-5-yl)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazoleHCL

5-propan-2-yl-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

(2R,3R,4S)-3-butyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

(2R,3S,4S)-3-prop-2-enyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

5-pentan-2-yl-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

(1R,1aS,5aR)-1-Methyl-4-(1H-tetrazol-5-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene

5-butyl-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

2-(difluoromethyl)-5-isopentyl-3H-pyrano[2,3-d]pyrimidine-4,7-dione

(4aR,5R,5aR)-5-[(1E)-prop-1-enyl]-3-(1H-tetrazol-5-yl)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole

(2R,3S,4S)-3-ethyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

2-(difluoromethyl)-5-(3-(1-fluorocyclopropyl)propyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole

5-methyl-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

2-(difluoromethyl)-5-hexyl-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-(2-methylbutyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

2-(difluoromethyl)-5-(3-(1-ethylcyclopropyl)propyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-ethyl-2-(fluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

2-(difluoromethyl)-5-ethyl-3H-pyrano[2,3-d]pyrimidine-4,7-dione

2-(difluoromethyl)-5-(2-(3-methylcyclobutyl)ethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-(3-iodo-phenyl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid

5-(2-cyclopropylethyl)-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

N-[2-(4-fluorophenoxy)ethyl]-7-methyl-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide

5-ethyl-2-mercapto-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-(3-methylsulfonylpropyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-(3-cyclobutylpropyl)-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-methyl-5-(5-methyl-thiophen-2-yl)-4-oxo-4,5-dihydro-furan-2-carboxylic acid

(4aR,5R,5aS)-5-ethyl-3-(1H-tetrazol-5-yl)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole

(4aR,5R,5aR)-5-cyclopropyl-3-(1H-tetrazol-5-yl)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole

(1R,1aS,5aR)-1-Propyl-4-(1H-tetrazol-5-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene

5-(4-cyclopropylbutyl)-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

7-methyl-N-(1-phenoxypropan-2-yl)-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide

5-methyl-5-(4-bromo-thiophen-2-yl)-4-oxo-4,5-dihydro-furan-2-carboxylic acid

2-(difluoromethyl)-5-(3-(1-isopropylcyclopropyl)propyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-(cyclobutylmethyl)-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

(2S,3S,4R)-3-(methylsulfanylmethyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

3-(4-isopropylphenyl)-N-(2-(3-methoxyphenoxy)ethyl)-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide

ethyl 2-(2,4,7-trioxo-1H-pyrano[2,3-d]pyrimidin-5-yl)acetate

3,3-dimethyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

5-(3-bi(cycloprop)ylpropyl)-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-(3-ethyl-phenyl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid

(4aR,5S,5aR)-3-(1H-tetrazol-5-yl)-5-vinyl-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole

5-ethyl-2-(hydroxymethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

(2R,3R,4S)-3-pentyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

(2S,3S,4R)-3-methyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

5-(3-fluoro-phenyl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid

5-ethyl-2-(trifluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

(2S,3R,4S)-3-ethenyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

3-(4-isopropylphenyl)-7-methyl-N-(2-(m-tolyloxy)ethyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide

3-(4-isopropylphenyl)-N-(2-(4-methoxyphenoxy)ethyl)-7-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide

5-(1-hydroxyethyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

N-(1-methoxy-3-phenylpropan-2-yl)-7-methyl-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide

5-(2-cyclopentylethyl)-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

(4aR,5R,5aS)-5-allyl-3-(1H-tetrazol-5-yl)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole

5-(3-chloro-phenyl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid

5-(2,2,2-trifluoroethyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

(2R,3S,4S)-3-propyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

(2R,3R,4S)-3-propyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

N-[2-(2-fluorophenoxy)ethyl]-7-methyl-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide

(4aS,5R,5aR)-5-(methoxymethyl)-3-(1H-tetrazol-5-yl)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole

N-(2-methoxy-1-phenylethyl)-7-methyl-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide

(2S,3R,4S)-3-cyclopropyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

5-cyclohex-1-enyl-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid

(2'R,4'S)-7'-(1H-1,2,3,4-tetrazol-5-yl)-8',9'-diazaspiro[cyclopentane-1,3'-tricyclo[4.3.0.0^{2,4}]nonane]-1'(6'),7'-diene

5-(5-chloro-thiophen-2-yl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid

3-(4-isopropylphenyl)-7-methyl-N-(2-(p-tolyloxy)ethyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide

N-[2-(4-chlorophenoxy)ethyl]-7-methyl-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide

3-(4-isopropylphenyl)-7-methyl-N-(2-(naphthalen-2-yloxy)ethyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide

(1S,1aS,5aR)-1-Methyl-4-(1H-tetrazol-5-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene

5-methyl-4-oxo-5-thiophen-3-yl-4,5-dihydro-furan-2-carboxylic acid

(5R,5aS)-5-isobutyl-3-(1H-tetrazol-5-yl)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole

(2S,3S,4R)-3-(methoxymethyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

5-cyclopent-1-enyl-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid

5-(3,5-difluoro-phenyl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid

2-(chlorofluoromethyl)-5-ethyl-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-methyl-5-(4-methyl-thiophen-2-yl)-4-oxo-4,5-dihydro-furan-2-carboxylic acid

(4aS,5aR)-5,5-dimethyl-3-(1H-tetrazol-5-yl)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole

(S)-3-(4-isopropylphenyl)-7-methyl-N-(1-phenoxypropan-2-yl)pyrazolo[1,5-a]pyrimidine-6-carboxamide

5-ethyl-2-(phenoxymethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

2-(difluoromethyl)-5-(3-(1-phenylcyclopropyl)propyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

N-(1-methoxypropan-2-yl)-7-methyl-3-(4-propan-2-ylphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide

5-ethyl-2-(methoxymethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

(4aR,5R,5aS)-5-butyl-3-(1H-tetrazol-5-yl)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole

5-(2-cyclohexylethyl)-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-methyl-4-oxo-5-(3-trifluoromethyl-phenyl)-4,5-dihydro-furan-2-carboxylic acid

2-(difluoromethyl)-5-propyl-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-methyl-4-oxo-5-thiophen-2-yl-4,5-dihydro-furan-2-carboxylic acid

5-Methyl-4-oxy-pyrazine-2-carboxylic acid

(2R,3S,4S)-3-(2-methylpropyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

5-(4-fluoro-phenyl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid

5-methyl-4-oxo-5-m-tolyl-4,5-dihydro-furan-2-carboxylic acid

(2R,3S,4S)-3-butyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

5-(2-fluoro-phenyl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid

3-(4-isopropylphenyl)-7-methyl-N-(2-phenoxyethyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide

5-ethyl-2-(1-fluoroethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-(2,6-difluoro-phenyl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid

5-(3-phenylpropyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

2-(difluoromethyl)-5-methyl-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-(4-bromo-5-methyl-thiophen-2-yl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid

5-(3,4-difluoro-phenyl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid

5-ethyl-4,7-dioxo-4,7-dihydro-3H-pyrano[2,3-d]pyrimidine-2-carbonitrile

5-ethyl-2-(prop-1-en-2-yl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-(cyclopropylmethyl)-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

2-butyl-5-ethyl-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-ethyl-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-ethyl-2-isopropyl-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-ethyl-2-phenethyl-3H-pyrano[2,3-d]pyrimidine-4,7-dione

2-(difluoromethyl)-5-(3-(1-(hydroxymethyl)cyclopropyl)propyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-cyclobutyl-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-ethyl-2-(piperidin-1-ylmethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

2-(difluoro(phenyl)methyl)-5-ethyl-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-ethyl-2-(4-(trifluoromethyl)phenyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-ethyl-2-(phenylsulfonylmethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

2-cyclopropyl-5-ethyl-3H-pyrano[2,3-d]pyrimidine-4,7-dione

methyl 5-ethyl-4,7-dioxo-3H-pyrano[2,3-d]pyrimidine-2-carboxylate

5-cyclopropyl-2-(difluoromethyl)-3H-pyrano[2,3-d]pyrimidine-4,7-dione

5-(3,3-dimethylbutyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-(trifluoromethyl)-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

5-phenyl-1H-pyrano[2,3-d]pyrimidine-2,4,7-trione

methyl 2,4,7-trioxo-1H-pyrano[2,3-d]pyrimidine-5-carboxylate

spiro[8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-3,1'-cyclohexane]-7-carboxylic acid

(2S,3S,4S)-3-phenyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

(2S,3R,4S)-3-propan-2-yl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

(2S,3S,4R)-3-(ethoxymethyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

(2S,3R,4R)-3-(phenoxymethyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid

(2R,3S,4S)-3-(3-methylbutyl)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid