| Compound ID |
Compound Name |
Compound Formula |
|
CP0374289
|
1-(2-(1-methyl-1H-pyrazol-3-yl)-1H-benzo[d]imidazole-5-carbonyl)-6'-(1-methyl-1H-pyrazol-4-yl)spiro[piperidine-4,2'-pyrano[2,3-c]pyridin]-4'(3'H)-one
Show/Hide
|
C28H26N8O3
|
1
|
| 1 |
IC50 = 0.21 nM
|
|
|
|
CP0485729
|
1-(7-methyl-1H-indazole-5-carbonyl)-6'-(1-methyl-1H-pyrazol-4-yl)spiro[piperidine-4,2'-pyrano[2,3-c]pyridin]-4'(3'H)-one
Show/Hide
|
C25H24N6O3
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0532675
|
6'-methoxy-1-(7-methyl-1H-indazole-5-carbonyl)spiro[piperidine-4,2'-pyrano[2,3-c]pyridin]-4'(3'H)-one
Show/Hide
|
C22H22N4O4
|
1
|
| 1 |
IC50 = 0.31 nM
|
|
|
|
CP0447631
|
5'-isopropoxy-1-(7-methyl-1H-indazole-5-carbonyl)spiro[piperidine-4,2'-pyrano[3,2-c]pyridin]-4'(3'H)-one
Show/Hide
|
C24H26N4O4
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0532674
|
1'-(7-methyl-1H-indazole-5-carbonyl)-6-(1H-pyrazol-3-yl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C25H23N5O3
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0470464
|
1'-(7-methyl-1H-indazole-5-carbonyl)-6-(1-methyl-1H-pyrazol-3-yl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C26H25N5O3
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0374288
|
6-(3,5-dimethylisoxazol-4-yl)-1'-(7-methyl-1H-indazole-5-carbonyl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C27H26N4O4
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0504321
|
5-methoxy-1'-(7-methyl-1H-indazole-5-carbonyl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C23H23N3O4
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0523701
|
2-tert-butyl-1'-(2,7-dimethyl-3H-benzimidazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C24H29N5O3
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0431135
|
2-tert-butyl-1'-(7-methyl-1H-indazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C23H27N5O3
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
|
CP0403613
|
2-tert-butyl-1'-(7-methyl-3H-benzimidazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C23H27N5O3
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0504521
|
1'-(7-methyl-1H-indazole-5-carbonyl)-6-(5-methyl-1H-pyrazol-3-yl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C26H25N5O3
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0523699
|
2-cyclopentyl-1'-(7-methyl-1H-indazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C24H27N5O3
|
1
|
| 1 |
IC50 = 9.4 nM
|
|
|
|
CP0400022
|
5-(5-methoxy-4-oxospiro[chroman-2,4'-piperidine]-1'-ylcarbonyl)-N-methyl-1H-indole-2-carboxamide
Show/Hide
|
C25H25N3O5
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0490829
|
1'-(3,7-dimethyl-1H-indazole-5-carbonyl)-5-methoxyspiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C24H25N3O4
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0523703
|
1'-(3H-benzimidazole-5-carbonyl)-2-tert-butylspiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C22H25N5O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0374287
|
5-methoxy-1'-(2-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carbonyl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C27H24N4O4
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0476592
|
1'-(3,7-dimethyl-2H-indazole-5-carbonyl)-2-ethyl-3-methylspiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C23H27N5O3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0390866
|
1'-(3,7-dimethyl-2H-indazole-5-carbonyl)-2-propan-2-ylspiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C23H27N5O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0493894
|
2-cyclobutyl-1'-(7-methyl-1H-indazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C23H25N5O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0458950
|
5-(5-methoxy-4-oxospiro[chroman-2,4'-piperidine]-1'-ylcarbonyl)-1H-benzo[d]imidazole-2-carboxamide
Show/Hide
|
C23H22N4O5
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0519342
|
5-(5-methoxy-4-oxospiro[chroman-2,4'-piperidine]-1'-ylcarbonyl)-7-methyl-1H-indole-2-carboxamide
Show/Hide
|
C25H25N3O5
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0532673
|
5-methoxy-1'-(2-phenyl-1H-benzo[d]imidazole-5-carbonyl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C28H25N3O4
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0503010
|
1'-(7-ethoxy-3-ethyl-2H-indazole-5-carbonyl)-2-ethyl-3-methylspiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C25H31N5O4
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0504520
|
5-methoxy-1'-(2-(pyridin-3-yl)-1H-benzo[d]imidazole-5-carbonyl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C27H24N4O4
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0458956
|
1-(3,7-dimethyl-1H-indazole-5-carbonyl)-5'-isopropoxyspiro[piperidine-4,2'-pyrano[3,2-c]pyridin]-4'(3'H)-one
Show/Hide
|
C25H28N4O4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0498561
|
1'-(3,7-dimethyl-2H-indazole-5-carbonyl)-3-methyl-2-(oxolan-3-yl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C25H29N5O4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0523702
|
2-tert-butyl-1'-(1-methylindazole-6-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C23H27N5O3
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0499773
|
1'-(7-methyl-1H-indazole-5-carbonyl)-2-propan-2-ylspiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C22H25N5O3
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0437639
|
1'-(7-ethoxy-3-methyl-2H-indazole-5-carbonyl)-2-ethyl-3-methylspiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C24H29N5O4
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0495482
|
1'-(3,7-dimethyl-1H-indole-5-carbonyl)-2-ethyl-3-methylspiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C24H28N4O3
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0447628
|
1'-(7-methyl-1H-indazole-5-carbonyl)-6-(2-methyloxazol-4-yl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C26H24N4O4
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0391924
|
2-ethyl-3-methyl-1'-(7-methyl-1H-indazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C22H25N5O3
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0523700
|
2-ethyl-1'-(7-ethyl-1H-indazole-5-carbonyl)-3-methylspiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C23H27N5O3
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0417721
|
1'-(7-methyl-1H-indazole-5-carbonyl)-6-(2-methyloxazol-5-yl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C26H24N4O4
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0462146
|
2-ethyl-3-methyl-1'-(3-methyl-2H-indazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C22H25N5O3
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0504163
|
1'-(7-methyl-1H-indazole-5-carbonyl)-2-propylspiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C22H25N5O3
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0374290
|
5'-methoxy-7'-methyl-1-(7-methyl-1H-indazole-5-carbonyl)spiro[piperidine-4,2'-pyrano[3,2-c]pyridin]-4'(3'H)-one
Show/Hide
|
C23H24N4O4
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0503009
|
6,7-dimethyl-1'-(7-methyl-1H-indazole-5-carbonyl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C24H25N3O3
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0485727
|
5-methoxy-1'-(2-(pyridin-4-yl)-1H-benzo[d]imidazole-5-carbonyl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C27H24N4O4
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0497172
|
1'-(2,7-dimethyl-3H-benzimidazole-5-carbonyl)-2-ethyl-3-methylspiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C23H27N5O3
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0495986
|
2-cyclohexyl-1'-(7-methyl-1H-indazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C25H29N5O3
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0523698
|
2-ethyl-1'-(7-methyl-1H-indazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C21H23N5O3
|
1
|
| 1 |
IC50 = 63 nM
|
|
|
|
CP0502944
|
2-ethyl-3-methyl-1'-(7-methyl-3H-benzimidazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C22H25N5O3
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0493895
|
2-ethyl-1'-(1H-indazole-5-carbonyl)-3-methylspiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C21H23N5O3
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0374291
|
5'-isobutoxy-1-(7-methyl-1H-indazole-5-carbonyl)spiro[piperidine-4,2'-pyrano[3,2-c]pyridin]-4'(3'H)-one
Show/Hide
|
C25H28N4O4
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0474834
|
2,2-dimethylpropyl (1S)-1-methyl-8-(7-methyl-1H-indazole-5-carbonyl)-2,8-diazaspiro[4.5]decane-2-carboxylate
Show/Hide
|
C24H34N4O3
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0447626
|
1'-(1H-benzo[d]imidazole-5-carbonyl)-5-methoxyspiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C22H21N3O4
|
1
|
| 1 |
IC50 = 111 nM
|
|
|
|
CP0485725
|
5-methoxy-1'-(7-methyl-1H-benzo[d]imidazole-5-carbonyl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C23H23N3O4
|
1
|
| 1 |
IC50 = 126 nM
|
|
|
|
CP0504322
|
1'-(7-ethyl-1H-indazole-5-carbonyl)-5-methoxyspiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C24H25N3O4
|
1
|
| 1 |
IC50 = 151 nM
|
|
|
|
CP0504519
|
5-methoxy-1'-(3-methyl-1H-indazole-6-carbonyl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C23H23N3O4
|
1
|
| 1 |
IC50 = 164 nM
|
|
|
|
CP0428475
|
2,2-dimethylpropyl (1R)-1-methyl-8-(7-methyl-1H-indazole-5-carbonyl)-2,8-diazaspiro[4.5]decane-2-carboxylate
Show/Hide
|
C24H34N4O3
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0474835
|
[(1R)-1-phenylethyl] 8-(7-methyl-1H-indazole-5-carbonyl)-2,8-diazaspiro[4.5]decane-2-carboxylate
Show/Hide
|
C26H30N4O3
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0507502
|
1-(3,7-dimethyl-1H-indazole-5-carbonyl)spiro[piperidine-4,2'-pyrano[3,2-b]pyridin]-4'(3'H)-one
Show/Hide
|
C22H22N4O3
|
1
|
| 1 |
IC50 = 363 nM
|
|
|
|
CP0507500
|
1'-(1H-indazole-7-carbonyl)-6,7-dimethylspiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C23H23N3O3
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0495608
|
2,3-dimethyl-1'-(7-methyl-1H-indazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C21H23N5O3
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0485726
|
1'-(1H-benzo[d][1,2,3]triazole-5-carbonyl)-5-methoxyspiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C21H20N4O4
|
1
|
| 1 |
IC50 = 505 nM
|
|
|
|
CP0470466
|
1-(3-methyl-1H-indazole-5-carbonyl)spiro[piperidine-4,2'-pyrano[3,2-b]pyridin]-4'(3'H)-one
Show/Hide
|
C21H20N4O3
|
1
|
| 1 |
IC50 = 640 nM
|
|
|
|
CP0543082
|
1'-(1H-indazol-7-ylcarbonyl)-6-methylspiro[chromene-2,4'-piperidin]-4(3H)-one
Show/Hide
|
C22H21N3O3
|
1
|
| 1 |
IC50 = 641 nM
|
|
|
|
CP0387787
|
2-methyl-1'-(7-methyl-1H-indazole-5-carbonyl)spiro[6H-pyrano[3,2-c]pyrazole-5,4'-piperidine]-7-one
Show/Hide
|
C20H21N5O3
|
1
|
| 1 |
IC50 = 650 nM
|
|
|
|
CP0384836
|
2,2-dimethylpropyl 8-(7-methyl-1H-indazole-5-carbonyl)-2,8-diazaspiro[4.5]decane-2-carboxylate
Show/Hide
|
C23H32N4O3
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0545026
|
tert-butyl 7-(7-methyl-1H-indazole-5-carbonyl)-2,7-diazaspiro[3.5]nonane-2-carboxylate
Show/Hide
|
C21H28N4O3
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0543528
|
[(1R)-1-phenylethyl] 7-(7-methyl-1H-indazole-5-carbonyl)-2,7-diazaspiro[3.5]nonane-2-carboxylate
Show/Hide
|
C25H28N4O3
|
1
|
| 1 |
IC50 = 880 nM
|
|
|
|
CP0428474
|
tert-butyl 3-methyl-7-(7-methyl-1H-indazole-5-carbonyl)-2,7-diazaspiro[3.5]nonane-2-carboxylate
Show/Hide
|
C22H30N4O3
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0530918
|
tert-butyl 8-(7-methyl-1H-indazole-5-carbonyl)-2,8-diazaspiro[4.5]decane-2-carboxylate
Show/Hide
|
C22H30N4O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0431556
|
2,2-dimethylpropyl (3R)-3,7-dimethyl-8-(7-methyl-1H-indazole-5-carbonyl)-2,8-diazaspiro[4.5]decane-2-carboxylate
Show/Hide
|
C25H36N4O3
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0468544
|
2,2-dimethylpropyl 7-(7-methyl-1H-indazole-5-carbonyl)-2,7-diazaspiro[3.5]nonane-2-carboxylate
Show/Hide
|
C22H30N4O3
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0504516
|
6-chloro-1'-(1H-indazole-7-carbonyl)spiro[chroman-2,4'-piperidin]-4-one
Show/Hide
|
C21H18ClN3O3
|
1
|
| 1 |
IC50 = 2130 nM
|
|
|
|
CP0428476
|
tert-butyl 2-(7-methyl-1H-indazole-5-carbonyl)-2,8-diazaspiro[4.5]decane-8-carboxylate
Show/Hide
|
C22H30N4O3
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0460268
|
tert-butyl 2-(7-methyl-1H-indazole-5-carbonyl)-2,7-diazaspiro[3.5]nonane-7-carboxylate
Show/Hide
|
C21H28N4O3
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0472466
|
benzyl 8-(7-methyl-1H-indazole-5-carbonyl)-2,8-diazaspiro[4.5]decane-2-carboxylate
Show/Hide
|
C25H28N4O3
|
1
|
| 1 |
IC50 = 4000 nM
|
|
|
|
CP0445454
|
propan-2-yl 8-(7-methyl-1H-indazole-5-carbonyl)-2,8-diazaspiro[4.5]decane-2-carboxylate
Show/Hide
|
C21H28N4O3
|
1
|
| 1 |
IC50 = 4500 nM
|
|
|
|
CP0481669
|
2,2-dimethylpropyl (3S)-3,7-dimethyl-8-(7-methyl-1H-indazole-5-carbonyl)-2,8-diazaspiro[4.5]decane-2-carboxylate
Show/Hide
|
C25H36N4O3
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0545025
|
tert-butyl 6-methyl-7-(7-methyl-1H-indazole-5-carbonyl)-2,7-diazaspiro[3.5]nonane-2-carboxylate
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C22H30N4O3
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1
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| 1 |
IC50 = 9200 nM
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CP0472458
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tert-butyl 6-(7-methyl-1H-indazole-5-carbonyl)-2,6-diazaspiro[3.3]heptane-2-carboxylate
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C19H24N4O3
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1
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| 1 |
IC50 > 10000 nM
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CP0559066
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tert-butyl 7-(7-methyl-1H-indazole-5-carbonyl)-2,7-diazaspiro[4.4]nonane-2-carboxylate
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C21H28N4O3
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1
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| 1 |
IC50 = 20000 nM
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CP0447627
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5-methoxy-1'-(2-methyl-1H-benzo[d]imidazole-5-carbonyl)spiro[chroman-2,4'-piperidin]-4-one
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C23H23N3O4
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1
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| 1 |
IC50 > 1000 nM
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CP0485723
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1'-(1H-indazole-7-carbonyl)-6,8-dimethylspiro[chroman-2,4'-piperidin]-4-one
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C23H23N3O3
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1
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| 1 |
IC50 > 1000 nM
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CP0495870
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1'-(1H-indazole-7-carbonyl)-5-methoxyspiro[chroman-2,4'-piperidin]-4-one
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C22H21N3O4
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1
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| 1 |
IC50 > 1000 nM
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