Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
 Cell Line Info 
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT00849 , Matrix metalloproteinase-9
 Protein Info 
Gene Name MMP9
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P14780
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011
 Cell Line Info 
 Protein ID: PT00849
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0191287
 Compound Info 
N-[2-[[(2R)-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-(4-phenylphenyl)sulfonylamino]ethyl]benzamide
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C26H29N3O5S
  1
1
IC50 = 2.5 nM
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CP0091600
 Compound Info 
1-N,3-N-bis[2-[[(2R)-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-(4-phenylphenyl)sulfonylamino]ethyl]benzene-1,3-dicarboxamide
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C46H52N6O10S2
  1
1
IC50 = 5.5 nM
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CP0344949
 Compound Info 
(2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide
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C18H23N3O5S
  1
1
IC50 = 10 nM
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CP0067113
 Compound Info 
(2R)-2-[2-[[3-[2-[[(1R)-1-carboxy-2-methylpropyl]-(4-phenylphenyl)sulfonylamino]ethylcarbamoyl]benzoyl]amino]ethyl-(4-phenylphenyl)sulfonylamino]-3-methylbutanoic acid
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C46H50N4O10S2
  1
1
IC50 = 26 nM
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CP0174419
 Compound Info 
(2R)-2-[2-[[3-[2-[[(2R)-1-(dimethylamino)-3-methyl-1-oxobutan-2-yl]-(4-phenylphenyl)sulfonylamino]ethylcarbamoyl]benzoyl]amino]ethyl-(4-phenylphenyl)sulfonylamino]-3-methylbutanoic acid
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C48H55N5O9S2
  1
1
IC50 = 34 nM
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CP0110637
 Compound Info 
1-N,3-N-bis[4-[[(3R)-4-(hydroxyamino)-4-oxo-3-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]butyl]amino]-4-oxobutyl]benzene-1,3-dicarboxamide
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C54H66N8O14S2
  1
1
IC50 = 38 nM
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CP0333590
 Compound Info 
3-N-[2-[[(2R)-1-(dimethylamino)-3-methyl-1-oxobutan-2-yl]-(4-phenylphenyl)sulfonylamino]ethyl]-1-N-[2-[[(2R)-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-(4-phenylphenyl)sulfonylamino]ethyl]benzene-1,3-dicarboxamide
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C48H56N6O9S2
  1
1
IC50 = 41 nM
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CP0072521
 Compound Info 
3-[[[2-(hydroxyamino)-2-oxoethyl]-(4-methoxyphenyl)sulfonylamino]methyl]benzoic acid
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C17H18N2O7S
  1
1
IC50 = 50 nM
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CP0199497
 Compound Info 
US9206139, 2
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C19H22F3N3O3
  1
1
IC50 = 439 nM
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CP0211045
 Compound Info 
(2R)-2-[2-benzamidoethyl-(4-phenylphenyl)sulfonylamino]-3-methylbutanoic acid
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C26H28N2O5S
  1
1
IC50 = 510 nM
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CP0069431
 Compound Info 
US9206139, 5
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C19H22F3N3O3
  1
1
IC50 = 7590 nM
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CP0408101
 Compound Info 
(1R,4aS,10aR)-1,4a-dimethyl-N-[(2S)-1-(3-methylanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2S)-1-(3-methylanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C52H60N4O5S
  1
1
IC50 = 8800 nM
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CP0069428
 Compound Info 
US9206139, 1
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C18H20F3N3O3
  1
1
IC50 = 12000 nM
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CP0438360
 Compound Info 
(1R,4aS,10aR)-1,4a-dimethyl-N-[(2S)-1-(4-methylanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2S)-1-(4-methylanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C52H60N4O5S
  1
1
IC50 = 20900 nM
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CP0422898
 Compound Info 
(1R,4aS,10aR)-N-[(2S)-1-anilino-1-oxo-3-phenylpropan-2-yl]-6-[[(2S)-1-anilino-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C50H56N4O5S
  1
1
IC50 = 24300 nM
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CP0444435
 Compound Info 
(1R,4aS,10aR)-1,4a-dimethyl-N-[(2S)-1-(2-methylanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2S)-1-(2-methylanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C52H60N4O5S
  1
1
IC50 = 27400 nM
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CP0427230
 Compound Info 
(1R,4aS,10aR)-1,4a-dimethyl-N-[(2R)-1-(2-methylanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-(2-methylanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C52H60N4O5S
  1
1
IC50 = 33600 nM
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CP0438363
 Compound Info 
(1R,4aS,10aR)-1,4a-dimethyl-N-[(2R)-1-(3-methylanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-(3-methylanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C52H60N4O5S
  1
1
IC50 = 34800 nM
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CP0519783
 Compound Info 
(4bS,8R,8aR)-8-[[(2S)-1-(4-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4b,8-dimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3-sulfonic acid
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C36H44N2O6S
  1
1
IC50 = 36300 nM
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CP0558200
 Compound Info 
(1R,4aS,10aR)-N-[(2S)-1-(2-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2S)-1-(2-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C52H60N4O7S
  1
1
IC50 = 43900 nM
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CP0435299
 Compound Info 
(1R,4aS,10aR)-N-[(2S)-1-(2-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2S)-1-(2-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C50H54F2N4O5S
  1
1
IC50 = 48300 nM
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CP0541179
 Compound Info 
(1R,4aS,10aR)-1,4a-dimethyl-N-[(2R)-1-(4-methylanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-(4-methylanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C52H60N4O5S
  1
1
IC50 = 51600 nM
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CP0519786
 Compound Info 
(1R,4aS,10aR)-N-[(2S)-1-(3-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2S)-1-(3-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C52H60N4O7S
  1
1
IC50 = 51900 nM
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CP0408103
 Compound Info 
(1R,4aS,10aR)-N-[(2R)-1-anilino-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-anilino-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C50H56N4O5S
  1
1
IC50 = 53600 nM
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CP0427228
 Compound Info 
(1R,4aS,10aR)-N-[(2S)-1-(4-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2S)-1-(4-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C52H60N4O7S
  1
1
IC50 = 54600 nM
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CP0438361
 Compound Info 
(1R,4aS,10aR)-N-[(2R)-1-(2-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-(2-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C52H60N4O7S
  1
1
IC50 = 56200 nM
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CP0516022
 Compound Info 
(1R,4aS,10aR)-N-[(2R)-1-(4-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-(4-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C52H60N4O7S
  1
1
IC50 = 57800 nM
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CP0541180
 Compound Info 
(1R,4aS,10aR)-N-[(2R)-1-(2-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-(2-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C50H54F2N4O5S
  1
1
IC50 = 66600 nM
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CP0410268
 Compound Info 
(4bS,8R,8aR)-8-[[(2S)-1-(3-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4b,8-dimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3-sulfonic acid
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C35H41FN2O5S
  1
1
IC50 = 72600 nM
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CP0520790
 Compound Info 
(4bS,8R,8aR)-8-[[(2S)-1-(2-bromoanilino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4b,8-dimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3-sulfonic acid
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C35H41BrN2O5S
  1
1
IC50 = 82600 nM
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CP0408098
 Compound Info 
(1R,4aS,10aR)-N-[(2R)-1-(3-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-(3-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C52H60N4O7S
  1
1
IC50 = 83400 nM
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CP0408097
 Compound Info 
(1R,4aS,10aR)-N-[(2S)-1-(3-bromoanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2S)-1-(3-bromoanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C50H54Br2N4O5S
  1
1
IC50 = 93100 nM
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CP0520785
 Compound Info 
(4bS,8R,8aR)-8-[[(2R)-1-anilino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4b,8-dimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3-sulfonic acid
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C35H42N2O5S
  1
1
IC50 = 95900 nM
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CP0069429
 Compound Info 
US9206139, 4
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C20H24F3N3O3
  1
1
IC50 > 100000 nM
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CP0118960
 Compound Info 
US9206139, 3
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C20H22F3N3O3
  1
1
IC50 > 100000 nM
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CP0408099
 Compound Info 
(4bS,8R,8aR)-8-[[(2R)-1-(2-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4b,8-dimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3-sulfonic acid
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C35H41FN2O5S
  1
1
IC50 > 100000 nM
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CP0408100
 Compound Info 
(1R,4aS,10aR)-N-[(2R)-1-(3-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-(3-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C50H54F2N4O5S
  1
1
IC50 > 100000 nM
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CP0410269
 Compound Info 
(4bS,8R,8aR)-8-[[(2S)-1-(2-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4b,8-dimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3-sulfonic acid
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C35H41FN2O5S
  1
1
IC50 > 100000 nM
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CP0410270
 Compound Info 
(4bS,8R,8aR)-8-[[(2S)-1-(2-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4b,8-dimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3-sulfonic acid
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C36H44N2O6S
  1
1
IC50 > 100000 nM
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CP0410271
 Compound Info 
(1R,4aS,10aR)-N-[(2R)-1-(4-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-(4-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C50H54F2N4O5S
  1
1
IC50 > 100000 nM
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CP0410272
 Compound Info 
(1R,4aS,10aR)-N-[(2R)-1-(3-chloro-4-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-(3-chloro-4-fluoroanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C50H52Cl2F2N4O5S
  1
1
IC50 > 100000 nM
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CP0435300
 Compound Info 
(4bS,8R,8aR)-8-[[(2R)-1-(2-bromoanilino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4b,8-dimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3-sulfonic acid
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C35H41BrN2O5S
  1
1
IC50 > 100000 nM
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CP0444437
 Compound Info 
(4bS,8R,8aR)-8-[[(2R)-1-(2-methoxyanilino)-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4b,8-dimethyl-2-propan-2-yl-5,6,7,8a,9,10-hexahydrophenanthrene-3-sulfonic acid
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C36H44N2O6S
  1
1
IC50 > 100000 nM
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CP0520788
 Compound Info 
(1R,4aS,10aR)-N-[(2R)-1-(3-bromoanilino)-1-oxo-3-phenylpropan-2-yl]-6-[[(2R)-1-(3-bromoanilino)-1-oxo-3-phenylpropan-2-yl]sulfamoyl]-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthrene-1-carboxamide
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C50H54Br2N4O5S
  1
1
IC50 > 100000 nM
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