Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
 Cell Line Info 
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT00660 , C-C chemokine receptor type 6
 Protein Info 
Gene Name CCR6
Organism Macaca mulatta, Rhesus macaque
Protein Classification Unclassified protein
Uniprot ID H9YX08
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011
 Cell Line Info 
 Protein ID: PT00660
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0086294
 Compound Info 
4-[4-[4-[[5-(trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]pyridine-2-carboxamide
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C24H23F3N4O3S
  1
1
IC50 = 0.45 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0416487
 Compound Info 
5-[4-[4-[[5-(trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]pyridine-2-carboxamide
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C24H23F3N4O3S
  1
1
IC50 = 9.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0416488
 Compound Info 
4-[4-[4-[[5-(trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]benzamide
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C25H24F3N3O3S
  1
1
IC50 = 16 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0457807
 Compound Info 
4-[4-[4-[[5-(trifluoromethyl)pyridin-2-yl]amino]cyclohexyl]sulfonylphenyl]benzonitrile
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C25H22F3N3O2S
  1
1
IC50 = 21 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0416486
 Compound Info 
6-[[1-(4-phenylphenyl)sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrile
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C23H22N4O2S
  1
1
IC50 = 280 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0396564
 Compound Info 
6-[[1-(4-methylphenyl)sulfonylpiperidin-4-yl]amino]pyridine-3-carbonitrile
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C18H20N4O2S
  1
1
IC50 = 1300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS