Brief Information of the Cell Line and Protein
Cell Line ID: CL000008 , H4
 Cell Line Info 
Synonyms
H-4
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1239
Protein ID: PT06942 , Tyrosine aminotransferase
 Protein Info 
Gene Name TAT
Organism Rattus norvegicus, Rat
Protein Classification Enzyme
Uniprot ID P04694
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000008
 Cell Line Info 
 Protein ID: PT06942
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0201812
 Compound Info 
(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl cyclohexylcarbamate
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C29H40FNO6
  1
1
EC50 = 2 nM
 Bioactivity Info 
   TI
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CP0310368
 Compound Info 
(11beta,16beta)-9-Fluoro-11,21-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl tert-butylcarbamate
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C27H38FNO6
  1
1
EC50 = 5.3 nM
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CP0269645
 Compound Info 
Adamantan-1-yl-carbamic acid (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxy-acetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl este
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C33H44FNO6
  1
1
EC50 = 9.8 nM
 Bioactivity Info 
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CP0264394
 Compound Info 
(11beta,16beta)-9-Fluoro-11,21-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl (1S)-1-phenylethylcarbamate
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C31H38FNO6
  1
1
EC50 = 37.3 nM
 Bioactivity Info 
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CP0285810
 Compound Info 
(11beta,16beta)-9-Fluoro-11,21-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl (1R)-1-phenylethylcarbamate
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C31H38FNO6
  1
1
EC50 = 70.3 nM
 Bioactivity Info 
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CP0340421
 Compound Info 
(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentylcarbamate
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C28H40FNO6
  1
1
EC50 = 117 nM
 Bioactivity Info 
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CP0340420
 Compound Info 
(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl 2,4,4-trimethylpentan-2-ylcarbamate
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C31H46FNO6
  1
1
EC50 = 156 nM
 Bioactivity Info 
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CP0269642
 Compound Info 
(11beta,16beta)-9-Fluoro-11,21-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl (1S)-1-(methoxycarbonyl)-ethylcarbamate
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C27H36FNO8
  1
1
EC50 = 211 nM
 Bioactivity Info 
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CP0201809
 Compound Info 
(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl 3,3-dimethylbutylcarbamate
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C29H42FNO6
  1
1
EC50 = 646 nM
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CP0310367
 Compound Info 
(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl tert-pentylcarbamate
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C28H40FNO6
  1
1
EC50 = 705 nM
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