Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT06668 , 5-hydroxytryptamine receptor 1B
Gene Name HTR1B
Organism Gorilla gorilla gorilla, Western lowland gorilla
Protein Classification Membrane receptor
Uniprot ID Q9N2B7
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT06668
 
Compound ID Compound Name Compound Formula
CP0005653
(3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide
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C14H21N3O2S
 1
1
Ki = 6.4 nM
   TI
   LI
   LO
   TS
CP0449615
(S)-1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
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C23H29N3O3
 1
1
Ki = 3023 nM
   TI
   LI
   LO
   TS
CP0446013
(S)-1-(2-(4-(4-methoxyphenyl)piperazin-1-yl)ethyl)-N-methyl-3,4-dihydro-1H-isochromene-6-carboxamide
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C24H31N3O3
 1
1
Ki = 5775 nM
   TI
   LI
   LO
   TS
CP0402145
1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
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C23H29N3O3
 1
1
Ki = 5862 nM
   TI
   LI
   LO
   TS
CP0391252
1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-piperazine
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C22H28N2O2
 1
1
Ki = 7242 nM
   TI
   LI
   LO
   TS
CP0403969
(R)-1-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide
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C23H29N3O3
 1
1
Ki = 26021 nM
   TI
   LI
   LO
   TS