Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT06627 , Short transient receptor potential channel 7
Gene Name TRPC7
Organism Homo sapiens, Human
Protein Classification Unclassified protein
Uniprot ID Q9HCX4
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT06627
 
Compound ID Compound Name Compound Formula
CP0386836
CHEMBL4085233
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C22H23F3N4O3
 1
1
EC50 = 90 nM
   TI
   LI
   LO
   TS
CP0386835
benzyl 4-[3-(4-chlorophenyl)-2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylate
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C26H25ClN4O3
 1
1
EC50 = 213 nM
   TI
   LI
   LO
   TS
CP0393949
CHEMBL4060400
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C26H25FN4O3
 1
1
EC50 = 314 nM
   TI
   LI
   LO
   TS
CP0386837
ethyl 4-[3-(4-fluorophenyl)-2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carboxylate
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C21H23FN4O3
 2
1
EC50 = 497 nM
   TI
   LI
   LO
   TS
2
EC50 = 1130 nM
   TI
   LI
   LO
   TS