Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT06240 , Adenosine receptor A3
 Protein Info 
Gene Name ADORA3
Organism Canis lupus familiaris, Dog, Canis familiaris
Protein Classification Membrane receptor
Uniprot ID Q28309
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT06240
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0089367
 Compound Info 
(1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(methylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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C20H19ClN6O3S
  1
1
IC50 = 8500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0484479
 Compound Info 
(1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(ethylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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C21H21ClN6O3S
  1
1
Ki = 1.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0236158
 Compound Info 
(1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(propylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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C22H23ClN6O3S
  1
1
Ki = 5.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0108871
 Compound Info 
(1S,2R,3S,4R,5S)-4-[5-[2-(5-chlorothiophen-2-yl)ethynyl]-7-(ethylamino)imidazo[4,5-b]pyridin-3-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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C22H22ClN5O3S
  1
1
Ki = 49 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0380403
 Compound Info 
(1S,2R,3S,4R,5S)-4-[5-[2-(5-chlorothiophen-2-yl)ethynyl]-7-(methylamino)imidazo[4,5-b]pyridin-3-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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C21H20ClN5O3S
  1
1
Ki = 75 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS