Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT06208 , Sodium-dependent neutral amino acid transporter B(0)AT2
 Protein Info 
Gene Name SLC6A15
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID Q9H2J7
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT06208
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0411297
 Compound Info 
1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]pentan-1-one
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C24H27ClN2O
  1
1
IC50 = 3400 nM
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CP0068895
 Compound Info 
ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
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C22H23ClN2O2
  1
1
IC50 = 4000 nM
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CP0386698
 Compound Info 
ethyl 4-(13-chloro-6-methoxy-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
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C23H25ClN2O3
  1
1
IC50 = 4500 nM
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CP0411480
 Compound Info 
propyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
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C23H25ClN2O2
  1
1
IC50 = 4600 nM
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CP0386804
 Compound Info 
1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-butan-1-one
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C23H25ClN2O
  1
1
IC50 = 4900 nM
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CP0535279
 Compound Info 
prop-2-enyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
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C23H23ClN2O2
  1
1
IC50 = 4900 nM
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CP0504705
 Compound Info 
(E)-1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]but-2-en-1-one
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C23H23ClN2O
  1
1
IC50 = 5000 nM
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CP0518714
 Compound Info 
1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]hexan-1-one
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C25H29ClN2O
  1
1
IC50 = 5200 nM
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CP0379350
 Compound Info 
S-ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carbothioate
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C22H23ClN2OS
  1
1
IC50 = 5300 nM
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CP0398237
 Compound Info 
1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]-2-cyclohexylethanone
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C27H31ClN2O
  1
1
IC50 = 5700 nM
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CP0386697
 Compound Info 
(2R)-2-amino-1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]-4-methylpentan-1-one
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C25H30ClN3O
  1
1
IC50 = 7700 nM
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CP0386876
 Compound Info 
2-methylpropyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
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C24H27ClN2O2
  1
1
IC50 = 7800 nM
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CP0398417
 Compound Info 
1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]-3-methylbutan-1-one
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C24H27ClN2O
  1
1
IC50 = 10800 nM
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CP0554028
 Compound Info 
methyl 13-chloro-2-(1-ethoxycarbonylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene-5-carboxylate
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C24H25ClN2O4
  1
1
IC50 = 12400 nM
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CP0498170
 Compound Info 
ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylate
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C22H23ClN2O2
  1
1
IC50 = 14800 nM
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CP0017055
 Compound Info 
1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-phenyl-ethanone
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C27H25ClN2O
  1
1
IC50 = 16100 nM
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CP0398485
 Compound Info 
propan-2-yl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
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C23H25ClN2O2
  1
1
IC50 = 16800 nM
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CP0535281
 Compound Info 
ethyl 4-(13-chloro-6-hydroxy-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
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C22H23ClN2O3
  1
1
IC50 = 17600 nM
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CP0504706
 Compound Info 
ethyl 4-[13-chloro-7-(hydroxymethyl)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene]piperidine-1-carboxylate
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C23H25ClN2O3
  1
1
IC50 = 18300 nM
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CP0411296
 Compound Info 
3-amino-1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]propan-1-one
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C22H24ClN3O
  1
1
IC50 = 18700 nM
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CP0398240
 Compound Info 
methyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
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C21H21ClN2O2
  1
1
IC50 = 19600 nM
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CP0025634
 Compound Info 
2-Amino-1-[4-(8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-ethanone
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C21H22ClN3O
  1
1
IC50 = 22900 nM
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CP0398482
 Compound Info 
1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]-2-methoxyethanone
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C22H23ClN2O2
  1
1
IC50 = 26400 nM
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CP0535280
 Compound Info 
4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)-N-ethylpiperidine-1-carboxamide
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C22H24ClN3O
  1
1
IC50 = 35000 nM
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CP0398484
 Compound Info 
1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-propan-1-one
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C22H23ClN2O
  1
1
IC50 = 36000 nM
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CP0386802
 Compound Info 
(2R)-2-amino-1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]-3-methylbutan-1-one
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C24H28ClN3O
  1
1
IC50 = 39100 nM
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CP0264804
 Compound Info 
8-Chloro-11-[1-(5-methyl-pyridin-3-ylmethyl)-piperidin-4-ylidene]-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
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C26H26ClN3
  1
1
IC50 > 40000 nM
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CP0498705
 Compound Info 
1-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]-2-methylpropan-1-one
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C23H25ClN2O
  1
1
IC50 = 41500 nM
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CP0024186
 Compound Info 
1-[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-ethanone
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C21H21ClN2O
  1
1
IC50 = 54800 nM
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CP0386699
 Compound Info 
13-chloro-2-(1-propylsulfonylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene
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C22H25ClN2O2S
  1
1
IC50 > 80000 nM
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CP0386803
 Compound Info 
13-chloro-2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene
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C20H21ClN2
  1
1
IC50 > 80000 nM
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CP0398238
 Compound Info 
tert-butyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
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C24H27ClN2O2
  1
1
IC50 > 80000 nM
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CP0398242
 Compound Info 
ethyl 4-(13-chloro-7-cyano-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
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C23H22ClN3O2
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1
IC50 > 80000 nM
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CP0418690
 Compound Info 
ethyl 4-[13-chloro-5-(hydroxymethyl)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]piperidine-1-carboxylate
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C23H25ClN2O3
  1
1
IC50 > 80000 nM
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CP0513036
 Compound Info 
ethyl 4-(13-chloro-5-cyano-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
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C23H22ClN3O2
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1
IC50 > 80000 nM
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CP0515781
 Compound Info 
benzyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
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C27H25ClN2O2
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1
IC50 > 80000 nM
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CP0554029
 Compound Info 
phenyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
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C26H23ClN2O2
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1
IC50 > 80000 nM
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