Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT06207 , Vasopressin V1a receptor
Gene Name AVPR1A
Organism Mus musculus, Mouse
Protein Classification Membrane receptor
Uniprot ID Q62463
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT06207
 
Compound ID Compound Name Compound Formula
CP0379178
[6-chloro-1-(1-methylpiperidin-4-yl)indol-3-yl]-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanone
   Show/Hide
C27H30ClN3O2
 1
1
Ki = 11 nM
   TI
   LI
   LO
   TS
CP0441648
[6-chloro-1-[[(2S)-1-methylpyrrolidin-2-yl]methyl]indol-3-yl]-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanone
   Show/Hide
C27H30ClN3O2
 1
1
Ki = 13 nM
   TI
   LI
   LO
   TS
CP0419751
2-[6-chloro-3-(spiro[1H-2-benzofuran-3,4'-piperidine]-1'-carbonyl)indol-1-yl]-N,N-dimethylacetamide
   Show/Hide
C25H26ClN3O3
 1
1
Ki = 14 nM
   TI
   LI
   LO
   TS
CP0244529
[6-chloro-1-[2-(dimethylamino)ethyl]indol-3-yl]-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanone
   Show/Hide
C25H28ClN3O2
 1
1
Ki = 39 nM
   TI
   LI
   LO
   TS
CP0379184
2-[6-chloro-3-(spiro[1H-2-benzofuran-3,4'-piperidine]-1'-carbonyl)indol-1-yl]-1-(4-methylpiperazin-1-yl)ethanone
   Show/Hide
C28H31ClN4O3
 1
1
Ki = 41 nM
   TI
   LI
   LO
   TS
CP0379185
[6-chloro-1-[[(2S)-pyrrolidin-2-yl]methyl]indol-3-yl]-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanone
   Show/Hide
C26H28ClN3O2
 1
1
Ki = 125 nM
   TI
   LI
   LO
   TS
CP0379179
2-[6-chloro-3-(spiro[1H-2-benzofuran-3,4'-piperidine]-1'-carbonyl)indol-1-yl]-N-[2-(dimethylamino)ethyl]acetamide
   Show/Hide
C27H31ClN4O3
 1
1
Ki = 177 nM
   TI
   LI
   LO
   TS
CP0246508
(1-benzyl-2-methylindol-3-yl)-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanone
   Show/Hide
C29H28N2O2
 1
1
Ki = 210 nM
   TI
   LI
   LO
   TS
CP0441646
(6-chloro-1H-indol-3-yl)-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylmethanone
   Show/Hide
C21H19ClN2O2
 1
1
Ki = 1012 nM
   TI
   LI
   LO
   TS
CP0379183
(6-chloro-1H-indol-3-yl)-spiro[5H-furo[3,4-b]pyridine-7,4'-piperidine]-1'-ylmethanone
   Show/Hide
C20H18ClN3O2
 1
1
Ki = 1018 nM
   TI
   LI
   LO
   TS
CP0498957
(6-chloro-1H-indol-3-yl)-(4-phenylpiperidin-1-yl)methanone
   Show/Hide
C20H19ClN2O
 1
1
Ki = 1491 nM
   TI
   LI
   LO
   TS
CP0433526
(6-chloro-1H-indol-3-yl)-[4-(2-chlorophenyl)piperazin-1-yl]methanone
   Show/Hide
C19H17Cl2N3O
 1
1
Ki = 1972 nM
   TI
   LI
   LO
   TS
CP0379180
3-[1-(6-chloro-1H-indole-3-carbonyl)piperidin-4-yl]-1H-benzimidazol-2-one
   Show/Hide
C21H19ClN4O2
 1
1
Ki = 2395 nM
   TI
   LI
   LO
   TS
CP0499768
(6-chloro-1H-indol-3-yl)-spiro[1H-furo[3,4-c]pyridine-3,4'-piperidine]-1'-ylmethanone
   Show/Hide
C20H18ClN3O2
 1
1
Ki = 2980 nM
   TI
   LI
   LO
   TS
CP0379182
(6-chloro-1H-indol-3-yl)-spiro[7H-furo[3,4-b]pyridine-5,4'-piperidine]-1'-ylmethanone
   Show/Hide
C20H18ClN3O2
 1
1
Ki = 4816 nM
   TI
   LI
   LO
   TS
CP0398079
(6-chloro-1H-indol-3-yl)-(2,2-dioxospiro[1H-2-benzothiophene-3,4'-piperidine]-1'-yl)methanone
   Show/Hide
C21H19ClN2O3S
 1
1
Ki = 5886 nM
   TI
   LI
   LO
   TS
CP0379181
(6-chloro-1H-indol-3-yl)-spiro[1,2-dihydroindole-3,4'-piperidine]-1'-ylmethanone
   Show/Hide
C21H20ClN3O
 1
1
Ki = 5890 nM
   TI
   LI
   LO
   TS
CP0419752
1H-indol-3-yl(spiro[1H-2-benzofuran-3,4'-piperidine]-1'-yl)methanone
   Show/Hide
C21H20N2O2
 1
1
Ki = 6620 nM
   TI
   LI
   LO
   TS