| Compound ID |
Compound Name |
Compound Formula |
|
CP0444988
|
N-(2-amino-2-oxoethyl)-6-[[(2S)-2-[[(2S)-2-[[(2R)-3-[(Z)-1,2-bis(diethoxyphosphoryl)ethenyl]sulfanyl-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-phenylpropanoyl]amino]-N-[2-(hexadecylamino)-2-oxoethyl]hexanamide
Show/Hide
|
C95H151N21O21P2S
|
1
|
| 1 |
EC50 = 1.1 nM
|
|
|
|
CP0480668
|
N-(2-amino-2-oxoethyl)-6-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2R)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]-3-sulfanylpropanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]-N-[2-(hexadecylamino)-2-oxoethyl]hexanamide
Show/Hide
|
C85H131N21O15S
|
1
|
| 1 |
EC50 = 4.2 nM
|
|
|
|
CP0563562
|
2-[[2-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[2-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-4-[[6-[(2-amino-2-oxoethyl)-[2-(hexadecylamino)-2-oxoethyl]amino]-6-oxohexyl]amino]-4-oxo-1-phenylbutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]pyrrolidin-1-yl]-1-oxo-3,3-diphenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]acetic acid
Show/Hide
|
C86H133N21O15S
|
1
|
| 1 |
EC50 = 4.2 nM
|
|
|
|
CP0887768
|
2-(2-{bis[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide tetrahydrochloride
Show/Hide
|
C30H33Cl4FN8O2
|
2
|
| 1 |
EC50 = 6 nM
|
|
|
| 2 |
EC50 = 97 nM
|
|
|
|
CP0429395
|
ditert-butyl (Z)-2-[(2R)-3-[[(2S)-1-[[(2S)-1-[[6-[(2-amino-2-oxoethyl)-[2-(hexadecylamino)-2-oxoethyl]amino]-6-oxohexyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]-3-oxopropyl]sulfanylbut-2-enedioate
Show/Hide
|
C97H149N21O19S
|
1
|
| 1 |
EC50 = 6.3 nM
|
|
|
|
CP0504907
|
(Z)-2-[(2R)-3-[[(2S)-1-[[(2S)-1-[[6-[(2-amino-2-oxoethyl)-[2-(hexadecylamino)-2-oxoethyl]amino]-6-oxohexyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]-3-oxopropyl]sulfanylbut-2-enediamide
Show/Hide
|
C89H135N23O17S
|
1
|
| 1 |
EC50 = 8.4 nM
|
|
|
|
CP0480666
|
N-(2-amino-2-oxoethyl)-6-[[(2S)-2-[[(2S)-2-[[(2R)-3-[(E)-1,2-bis(tert-butylsulfonyl)ethenyl]sulfanyl-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-phenylpropanoyl]amino]-N-[2-(hexadecylamino)-2-oxoethyl]hexanamide
Show/Hide
|
C95H149N21O19S3
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0448320
|
diethyl (Z)-2-[(2R)-3-[[(2S)-1-[[(2S)-1-[[6-[(2-amino-2-oxoethyl)-[2-(hexadecylamino)-2-oxoethyl]amino]-6-oxohexyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]-3-oxopropyl]sulfanylbut-2-enedioate
Show/Hide
|
C93H141N21O19S
|
1
|
| 1 |
EC50 = 10.4 nM
|
|
|
|
CP0397750
|
dimethyl (Z)-2-[(2R)-3-[[(2S)-1-[[(2S)-1-[[6-[(2-amino-2-oxoethyl)-[2-(hexadecylamino)-2-oxoethyl]amino]-6-oxohexyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]-3-oxopropyl]sulfanylbut-2-enedioate
Show/Hide
|
C91H137N21O19S
|
1
|
| 1 |
EC50 = 12.6 nM
|
|
|
|
CP0399572
|
N-(2-amino-2-oxoethyl)-6-[[(2S)-2-[[(2S)-5-carbamimidamido-2-[[(2R)-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]-3-[(Z)-1-phenyl-2-sulfamoylethenyl]sulfanylpropanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]-N-[2-(hexadecylamino)-2-oxoethyl]hexanamide
Show/Hide
|
C93H138N22O17S2
|
1
|
| 1 |
EC50 = 34 nM
|
|
|
|
CP0874584
|
1-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-chloropyridin-2-yl)methyl]-1H-pyrazole-4-carboxamide
Show/Hide
|
C21H22ClN7O
|
2
|
| 1 |
EC50 = 43 nM
|
|
|
| 2 |
EC50 = 470 nM
|
|
|
|
CP0456167
|
(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-N-[6-[(2-amino-2-oxoethyl)-[2-(hexadecylamino)-2-oxoethyl]amino]-6-oxohexyl]-8-benzhydryl-26-benzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide
Show/Hide
|
C86H128N18O12S3
|
1
|
| 1 |
EC50 = 44.2 nM
|
|
|
|
CP0460308
|
(5R,8S,11S,14R,17S,20R)-8-benzyl-11,17-bis[3-(diaminomethylideneamino)propyl]-20-(3,3-diphenylpropanoylamino)-N-[2-[2-[2-(hexadecanoylamino)ethoxy]ethoxy]ethyl]-7,10,13,16,19-pentaoxo-14-(sulfanylmethyl)-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide
Show/Hide
|
C75H112N14O10S3
|
1
|
| 1 |
EC50 = 52.3 nM
|
|
|
|
CP0415576
|
(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-8-benzhydryl-26-benzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide
Show/Hide
|
C60H79N15O9S3
|
1
|
| 1 |
EC50 = 54.3 nM
|
|
|
|
CP0880270
|
1-(2-((2-(1H-benzo[d]imidazol-2-yl)ethyl)amino)ethyl)-N-((3-fluoropyridin-2-yl)methyl)-1H-1,2,3-triazole-4-carboxamide
Show/Hide
|
C20H21FN8O
|
2
|
| 1 |
EC50 = 69 nM
|
|
|
| 2 |
EC50 = 170 nM
|
|
|
|
CP0874581
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-chloropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C21H21ClN6O2
|
2
|
| 1 |
EC50 = 71 nM
|
|
|
| 2 |
EC50 = 100 nM
|
|
|
|
CP0874591
|
2-(2-{bis[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C30H29FN8OS
|
2
|
| 1 |
EC50 = 71 nM
|
|
|
| 2 |
EC50 = 170 nM
|
|
|
|
CP0903130
|
1-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1H-pyrazole-4-carboxamide tetrahydrochloride
Show/Hide
|
C21H26Cl4FN7O
|
2
|
| 1 |
EC50 = 75 nM
|
|
|
| 2 |
EC50 = 620 nM
|
|
|
|
CP0456168
|
2-[[2-[[(2S,3R)-1-[[(5R,8S,14S,17S,20R,23S,26S,29R)-8-benzhydryl-26-benzyl-29-carbamoyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-trien-5-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]acetic acid
Show/Hide
|
C66H89N17O13S3
|
1
|
| 1 |
EC50 = 75.1 nM
|
|
|
|
CP0903120
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide trihydrochloride
Show/Hide
|
C21H24Cl3FN6O2
|
2
|
| 1 |
EC50 = 81 nM
|
|
|
| 2 |
EC50 = 420 nM
|
|
|
|
CP0445523
|
(8S,14S,17S,20R,23S,26S,29R)-N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-8-benzhydryl-26-benzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide
Show/Hide
|
C64H89N15O10S3
|
1
|
| 1 |
EC50 = 92.3 nM
|
|
|
|
CP0415575
|
(5R,8S,11S,14R,17S,20R)-8-benzyl-11,17-bis[3-(diaminomethylideneamino)propyl]-20-(3,3-diphenylpropanoylamino)-7,10,13,16,19-pentaoxo-14-(sulfanylmethyl)-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide
Show/Hide
|
C53H69N13O7S3
|
1
|
| 1 |
EC50 = 103.8 nM
|
|
|
|
CP0450586
|
(5R,8S,11S,14R,17S,20R)-8-benzyl-11,17-bis[3-(diaminomethylideneamino)propyl]-7,10,13,16,19-pentaoxo-14-(sulfanylmethyl)-20-(3,3,3-triphenylpropanoylamino)-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide
Show/Hide
|
C59H73N13O7S3
|
1
|
| 1 |
EC50 = 112.7 nM
|
|
|
|
CP0942114
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-5-chloro-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C21H23Cl4FN6OS
|
2
|
| 1 |
EC50 = 130 nM
|
|
|
| 2 |
EC50 = 740 nM
|
|
|
|
CP0901637
|
2-{1-[2-(1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C22H21FN6O2
|
2
|
| 1 |
EC50 = 150 nM
|
|
|
| 2 |
EC50 = 500 nM
|
|
|
|
CP0415621
|
(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-8-benzhydryl-26-benzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide
Show/Hide
|
C66H92N16O11S3
|
1
|
| 1 |
EC50 = 164.5 nM
|
|
|
|
CP0887764
|
1-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-{5H,6H,7H-cyclopenta[b]pyridin-7-yl}-1H-pyrazole-4-carboxamide trihydrochloride
Show/Hide
|
C23H28Cl3N7O
|
2
|
| 1 |
EC50 = 194 nM
|
|
|
| 2 |
EC50 = 750 nM
|
|
|
|
CP0480667
|
(Z)-3-[(2R)-3-[[(2S)-1-[[(2S)-1-[[6-[(2-amino-2-oxoethyl)-[2-(hexadecylamino)-2-oxoethyl]amino]-6-oxohexyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-2-[[(2S)-5-carbamimidamido-2-[[2-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[2-[(2-hydroxyacetyl)amino]acetyl]amino]butanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3,3-diphenylpropanoyl]pyrrolidin-2-yl]acetyl]amino]pentanoyl]amino]-3-oxopropyl]sulfanylprop-2-enoic acid
Show/Hide
|
C88H133N21O17S
|
1
|
| 1 |
EC50 = 218.1 nM
|
|
|
|
CP0901639
|
2-(2-{[2-(1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H21FN6OS
|
2
|
| 1 |
EC50 = 220 nM
|
|
|
| 2 |
EC50 = 530 nM
|
|
|
|
CP0903140
|
2-(2-{[2-(1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-5-carboxamide
Show/Hide
|
C21H21FN6O2
|
2
|
| 1 |
EC50 = 220 nM
|
|
|
| 2 |
EC50 = 930 nM
|
|
|
|
CP0513226
|
N-[(8S,11S,14R,17S,20S)-8-benzyl-11,17-bis[3-(diaminomethylideneamino)propyl]-7,10,13,16,19-pentaoxo-14-(sulfanylmethyl)-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(28),24,26-trien-20-yl]-3,3-diphenylpropanamide
Show/Hide
|
C52H68N12O6S3
|
1
|
| 1 |
EC50 = 268.8 nM
|
|
|
|
CP0460312
|
(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-8,26-dibenzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide
Show/Hide
|
C54H75N15O9S3
|
1
|
| 1 |
EC50 = 272.2 nM
|
|
|
|
CP0951377
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-chloropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C20H19ClN6O2
|
2
|
| 1 |
EC50 = 290 nM
|
|
|
| 2 |
EC50 = 1110 nM
|
|
|
|
CP0409698
|
2-[(3S,6S,9S,12S,15R,20R,23S,26S)-15-amino-20-[[(2S,3S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]carbamoyl]-3-benzyl-23-[(2S)-butan-2-yl]-9-[(1R)-1-hydroxyethyl]-6-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,22,25-heptaoxo-17,18-dithia-1,4,7,10,13,21,24-heptazabicyclo[24.3.0]nonacosan-12-yl]acetic acid
Show/Hide
|
C55H77N13O13S2
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0903142
|
2-{1-[2-(4-Fluoro-1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C22H20F2N6O2
|
2
|
| 1 |
EC50 = 320 nM
|
|
|
| 2 |
EC50 = 880 nM
|
|
|
|
CP0958111
|
2-(2-(2-(1H-benzo[d]imidazol-2-yl)ethylamino)ethyl)-N-(6,7-dihydro-5H-cyclopenta[b]pyridin-7-yl)thiazole-4-carboxamide
Show/Hide
|
C23H24N6OS
|
2
|
| 1 |
EC50 = 325 nM
|
|
|
| 2 |
EC50 = 620 nM
|
|
|
|
CP0456166
|
(5R,8S,11S,14R,17S,20S)-8-benzyl-11,17-bis[3-(diaminomethylideneamino)propyl]-20-(3,3-diphenylpropanoylamino)-7,10,13,16,19-pentaoxo-14-(sulfanylmethyl)-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(27),24(28),25-triene-5-carboxamide
Show/Hide
|
C53H69N13O7S3
|
1
|
| 1 |
EC50 = 335.3 nM
|
|
|
|
CP0534497
|
N-[(5R,8S,14S,17S,20R,23S,26S)-8-benzhydryl-26-benzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(36),33(37),34-trien-5-yl]hexadecanamide
Show/Hide
|
C73H106N14O8S3
|
1
|
| 1 |
EC50 = 369 nM
|
|
|
|
CP0874586
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-(pyridin-2-ylmethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H22N6OS
|
2
|
| 1 |
EC50 = 387 nM
|
|
|
| 2 |
EC50 = 1720 nM
|
|
|
|
CP0401063
|
N-[(2R)-1-[[(8S,11S,14R,17S,20R)-8-benzyl-11,17-bis[3-(diaminomethylideneamino)propyl]-7,10,13,16,19-pentaoxo-14-(sulfanylmethyl)-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(28),24,26-trien-20-yl]amino]-1-oxo-3,3-diphenylpropan-2-yl]hexadecanamide
Show/Hide
|
C68H99N13O7S3
|
1
|
| 1 |
EC50 = 458.3 nM
|
|
|
|
CP0880273
|
2-(2-{[2-(5-fluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C21H20F2N6O2
|
2
|
| 1 |
EC50 = 460 nM
|
|
|
| 2 |
EC50 = 600 nM
|
|
|
|
CP0874588
|
2-(2-{[2-(4-Fluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C21H20F2N6O2
|
2
|
| 1 |
EC50 = 460 nM
|
|
|
| 2 |
EC50 = 2120 nM
|
|
|
|
CP0509271
|
(10R,13S,19S,22S,25R,28S,31S,34R)-10-acetamido-13,31-dibenzyl-22,28-bis[3-(diaminomethylideneamino)propyl]-11,14,20,23,26,29,32-heptaoxo-25-(sulfanylmethyl)-2-oxa-8,36-dithia-12,15,21,24,27,30,33-heptazatetracyclo[36.2.2.23,6.015,19]tetratetraconta-1(40),3(44),4,6(43),38,41-hexaene-34-carboxamide
Show/Hide
|
C60H79N15O10S3
|
1
|
| 1 |
EC50 = 477.4 nM
|
|
|
|
CP0903127
|
2-(2-{[2-(4-Chloro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C21H20ClFN6O2
|
2
|
| 1 |
EC50 = 490 nM
|
|
|
| 2 |
EC50 = 2340 nM
|
|
|
|
CP0903122
|
2-(2-{[2-(4-Fluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H20F2N6OS
|
2
|
| 1 |
EC50 = 510 nM
|
|
|
| 2 |
EC50 = 1400 nM
|
|
|
|
CP0445524
|
(11R,14S,20S,23S,26R,29S,32S,35R)-11-acetamido-14,32-dibenzyl-23,29-bis[3-(diaminomethylideneamino)propyl]-12,15,21,24,27,30,33-heptaoxo-26-(sulfanylmethyl)-9,37-dithia-13,16,22,25,28,31,34-heptazatetracyclo[37.3.1.13,7.016,20]tetratetraconta-1(43),3(44),4,6,39,41-hexaene-35-carboxamide
Show/Hide
|
C61H81N15O9S3
|
1
|
| 1 |
EC50 = 516.9 nM
|
|
|
|
CP0874587
|
2-(2-{[2-(4,5-Difluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C21H19F3N6O2
|
2
|
| 1 |
EC50 = 518 nM
|
|
|
| 2 |
EC50 = 636 nM
|
|
|
|
CP0942115
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-5-chloro-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H18ClFN6OS
|
2
|
| 1 |
EC50 = 523 nM
|
|
|
| 2 |
EC50 = 720 nM
|
|
|
|
CP0904081
|
2-(2-{[2-(5-Fluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C21H23Cl3F2N6OS
|
2
|
| 1 |
EC50 = 530 nM
|
|
|
| 2 |
EC50 = 1600 nM
|
|
|
|
CP0538411
|
2-[[2-[[(2S,3R)-1-[[(5R,8S,14S,17S,20R,23S,26S,29R)-8,26-dibenzyl-29-carbamoyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-trien-5-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]acetic acid
Show/Hide
|
C60H85N17O13S3
|
1
|
| 1 |
EC50 = 531.7 nM
|
|
|
|
CP0871743
|
2-{1-[2-(5-fluoro-1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-5-carboxamide
Show/Hide
|
C22H20F2N6O2
|
2
|
| 1 |
EC50 = 549 nM
|
|
|
| 2 |
EC50 = 734 nM
|
|
|
|
CP0903146
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-(pyridin-2-ylmethyl)-1,3-oxazole-4-carboxamide trihydrochloride
Show/Hide
|
C21H25Cl3N6O2
|
2
|
| 1 |
EC50 = 571 nM
|
|
|
| 2 |
EC50 = 1230 nM
|
|
|
|
CP0957855
|
2-(2-{[(4-fluoro-1H-1,3-benzodiazol-2-yl)methyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H18F2N6OS
|
2
|
| 1 |
EC50 = 582 nM
|
|
|
| 2 |
EC50 = 1122 nM
|
|
|
|
CP0460314
|
(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-8,26-dibenzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.2.2.010,14]heptatriaconta-1(36),33(37),34-triene-29-carboxamide
Show/Hide
|
C54H75N15O9S3
|
1
|
| 1 |
EC50 = 585.6 nM
|
|
|
|
CP0944108
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-5-methyl-1,3-thiazole-4-carboxamide
Show/Hide
|
C22H23FN6OS
|
2
|
| 1 |
EC50 = 587 nM
|
|
|
| 2 |
EC50 = 2590 nM
|
|
|
|
CP0905656
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C21H23Cl3F2N6OS
|
2
|
| 1 |
EC50 = 590 nM
|
|
|
| 2 |
EC50 = 2790 nM
|
|
|
|
CP0456169
|
(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-8,26-dibenzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.4.0.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide
Show/Hide
|
C54H75N15O9S3
|
1
|
| 1 |
EC50 = 598.9 nM
|
|
|
|
CP0903121
|
N-[(3-fluoropyridin-2-yl)methyl]-2-[2-({2-[4-(trifluoromethyl)-1H-1,3-benzodiazol-2-yl]ethyl}amino)ethyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C22H20F4N6O2
|
2
|
| 1 |
EC50 = 628 nM
|
|
|
| 2 |
EC50 = 736 nM
|
|
|
|
CP0887766
|
2-{1-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-5-carboxamide
Show/Hide
|
C22H21FN6O2
|
2
|
| 1 |
EC50 = 630 nM
|
|
|
| 2 |
EC50 = 1030 nM
|
|
|
|
CP0951417
|
1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-chloropyridin-2-yl)methyl]-1H-pyrazole-4-carboxamide
Show/Hide
|
C20H20ClN7O
|
2
|
| 1 |
EC50 = 678 nM
|
|
|
| 2 |
EC50 = 1720 nM
|
|
|
|
CP0909892
|
5-chloro-N-(pyridin-2-ylmethyl)-2-(2-{1,8,12-triazatricyclo[7.4.0.02,7]trideca-2(7),3,5,8-tetraen-12-yl}ethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C22H21ClN6OS
|
2
|
| 1 |
EC50 = 679 nM
|
|
|
| 2 |
EC50 = 3100 nM
|
|
|
|
CP0947240
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-chloropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H19ClN6OS
|
2
|
| 1 |
EC50 = 689 nM
|
|
|
| 2 |
EC50 = 760 nM
|
|
|
|
CP0905660
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-5-chloro-N-[(3-chloropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H18Cl2N6OS
|
2
|
| 1 |
EC50 = 757 nM
|
|
|
| 2 |
EC50 = 1160 nM
|
|
|
|
CP0946518
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide trihydrochloride
Show/Hide
|
C20H22Cl3FN6O2
|
2
|
| 1 |
EC50 = 757 nM
|
|
|
| 2 |
EC50 = 1260 nM
|
|
|
|
CP0874577
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C20H22Cl3FN6OS
|
2
|
| 1 |
EC50 = 810 nM
|
|
|
| 2 |
EC50 = 1450 nM
|
|
|
|
CP0880284
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoro-6-methylpyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H21FN6OS
|
1
|
| 1 |
EC50 = 840 nM
|
|
|
|
CP0880280
|
1-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-(pyridin-2-ylmethyl)-1H-pyrazole-4-carboxamide
Show/Hide
|
C21H23N7O
|
2
|
| 1 |
EC50 = 885 nM
|
|
|
| 2 |
EC50 = 2620 nM
|
|
|
|
CP0903755
|
1-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1H-1,2,4-triazole-3-carboxamide
Show/Hide
|
C20H21FN8O
|
2
|
| 1 |
EC50 = 930 nM
|
|
|
| 2 |
EC50 = 3720 nM
|
|
|
|
CP0903753
|
2-(2-{[2-(4,6-Difluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C21H19F3N6O2
|
2
|
| 1 |
EC50 = 950 nM
|
|
|
| 2 |
EC50 = 1550 nM
|
|
|
|
CP0909890
|
2-(2-(2-(1H-benzo[d]imidazol-2-yl)ethylamino)ethyl)-N-((3-fluoropyridin-2-yl)methyl)-5-methyloxazole-4-carboxamide
Show/Hide
|
C22H23FN6O2
|
2
|
| 1 |
EC50 = 950 nM
|
|
|
| 2 |
EC50 = 6380 nM
|
|
|
|
CP0880267
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-methylpyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C21H25Cl3N6OS
|
2
|
| 1 |
EC50 = 1029 nM
|
|
|
| 2 |
EC50 = 1230 nM
|
|
|
|
CP0960687
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl](cyclopropylmethyl)amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C25H27FN6OS
|
1
|
| 1 |
EC50 = 1050 nM
|
|
|
|
CP0903762
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-5-carboxamide
Show/Hide
|
C21H21FN6OS
|
2
|
| 1 |
EC50 = 1130 nM
|
|
|
| 2 |
EC50 = 10100 nM
|
|
|
|
CP0947239
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-5-chloro-N-(pyridin-2-ylmethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H21ClN6OS
|
2
|
| 1 |
EC50 = 1188 nM
|
|
|
| 2 |
EC50 = 1600 nM
|
|
|
|
CP0874579
|
2-(2-{[2-(5-cyano-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C22H20FN7O2
|
2
|
| 1 |
EC50 = 1196 nM
|
|
|
| 2 |
EC50 = 1998 nM
|
|
|
|
CP0900251
|
2-{2-[(1H-1,3-benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-5-carboxamide
Show/Hide
|
C20H19FN6O2
|
2
|
| 1 |
EC50 = 1198 nM
|
|
|
| 2 |
EC50 = 1259 nM
|
|
|
|
CP0903124
|
Benzyl N-(3-{[2-(1H-1,3-benzodiazol-2-yl)ethyl][2-(4-{[(3-fluoropyridin-2-yl)methyl]carbamoyl}-1,3-thiazol-2-yl)ethyl]amino}propyl)carbamate
Show/Hide
|
C32H34FN7O3S
|
2
|
| 1 |
EC50 = 1207 nM
|
|
|
| 2 |
EC50 = 25940 nM
|
|
|
|
CP0880272
|
2-{1-[2-(4-Fluoro-1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-(pyridin-2-ylmethyl)-1,3-oxazole-4-carboxamide
Show/Hide
|
C22H21FN6O2
|
2
|
| 1 |
EC50 = 1231 nM
|
|
|
| 2 |
EC50 = 2525 nM
|
|
|
|
CP0909887
|
1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1H-pyrazole-4-carboxamide
Show/Hide
|
C20H20FN7O
|
2
|
| 1 |
EC50 = 1245 nM
|
|
|
| 2 |
EC50 = 4700 nM
|
|
|
|
CP0903109
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-5-chloro-N-(pyridin-2-ylmethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H19ClN6OS
|
2
|
| 1 |
EC50 = 1287 nM
|
|
|
| 2 |
EC50 = 1910 nM
|
|
|
|
CP0954546
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-methoxypyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H22N6O2S
|
1
|
| 1 |
EC50 = 1380 nM
|
|
|
|
CP0874583
|
1-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide
Show/Hide
|
C22H21F4N7O
|
2
|
| 1 |
EC50 = 1412 nM
|
|
|
| 2 |
EC50 = 4370 nM
|
|
|
|
CP0957856
|
2-(2-{[2-(4,7-Difluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C21H19F3N6O2
|
2
|
| 1 |
EC50 = 1420 nM
|
|
|
| 2 |
EC50 = 2270 nM
|
|
|
|
CP0946468
|
2-{1-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-chloropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C22H21ClN6OS
|
2
|
| 1 |
EC50 = 1459 nM
|
|
|
| 2 |
EC50 = 3550 nM
|
|
|
|
CP0874590
|
1-{1-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-fluoropyridin-2-yl)methyl]-1H-pyrazole-4-carboxamide
Show/Hide
|
C22H22FN7O
|
2
|
| 1 |
EC50 = 1462 nM
|
|
|
| 2 |
EC50 = 2840 nM
|
|
|
|
CP0951409
|
N-[(3-fluoropyridin-2-yl)methyl]-2-(2-{[2-(4-methoxy-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-1,3-oxazole-4-carboxamide
Show/Hide
|
C22H23FN6O3
|
2
|
| 1 |
EC50 = 1580 nM
|
|
|
| 2 |
EC50 = 24900 nM
|
|
|
|
CP0905659
|
2-{1-[2-(1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-(pyridin-2-ylmethyl)-1,3-oxazole-4-carboxamide
Show/Hide
|
C22H22N6O2
|
2
|
| 1 |
EC50 = 1608 nM
|
|
|
| 2 |
EC50 = 2760 nM
|
|
|
|
CP0944213
|
2-{1-[2-(1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-(pyridazin-3-ylmethyl)-1,3-oxazole-4-carboxamide
Show/Hide
|
C21H21N7O2
|
2
|
| 1 |
EC50 = 1690 nM
|
|
|
| 2 |
EC50 = 3860 nM
|
|
|
|
CP0880271
|
N-[(3-Fluoropyridin-2-yl)methyl]-2-(1-{2-[7-(trifluoromethyl)-1H-1,3-benzodiazol-2-yl]ethyl}azetidin-3-yl)-1,3-oxazole-4-carboxamide
Show/Hide
|
C23H20F4N6O2
|
2
|
| 1 |
EC50 = 1721 nM
|
|
|
| 2 |
EC50 = 3604 nM
|
|
|
|
CP0941149
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(2-cyanophenyl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C22H20N6OS
|
1
|
| 1 |
EC50 = 1790 nM
|
|
|
|
CP0941164
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(5-methylpyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H22N6OS
|
1
|
| 1 |
EC50 = 1810 nM
|
|
|
|
CP0901638
|
2-(2-{[(4-fluoro-1H-1,3-benzodiazol-2-yl)methyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C20H18F2N6O2
|
2
|
| 1 |
EC50 = 1828 nM
|
|
|
| 2 |
EC50 = 3176 nM
|
|
|
|
CP0900252
|
2-{1-[2-(4-Fluoro-1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-5-carboxamide
Show/Hide
|
C22H20F2N6O2
|
2
|
| 1 |
EC50 = 1840 nM
|
|
|
| 2 |
EC50 = 3170 nM
|
|
|
|
CP0955513
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-chloro-5-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H18ClFN6OS
|
1
|
| 1 |
EC50 = 1850 nM
|
|
|
|
CP0903128
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-5-chloro-N-(pyridazin-3-ylmethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H20ClN7OS
|
2
|
| 1 |
EC50 = 1850 nM
|
|
|
| 2 |
EC50 = 3580 nM
|
|
|
|
CP0903751
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-4-methyl-1,3-thiazole-5-carboxamide
Show/Hide
|
C22H23FN6OS
|
2
|
| 1 |
EC50 = 1890 nM
|
|
|
| 2 |
EC50 = 12900 nM
|
|
|
|
CP0874589
|
2-({[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}methyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C20H19FN6O2
|
2
|
| 1 |
EC50 = 2072 nM
|
|
|
| 2 |
EC50 = 3260 nM
|
|
|
|
CP0850093
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3,5-dimethylpyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C22H24N6OS
|
1
|
| 1 |
EC50 = 2110 nM
|
|
|
|
CP0903125
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-5-methyl-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H21FN6OS
|
2
|
| 1 |
EC50 = 2110 nM
|
|
|
| 2 |
EC50 = 3207 nM
|
|
|
|
CP0944214
|
1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-{5H,6H,7H-cyclopenta[b]pyridin-7-yl}-1H-pyrazole-4-carboxamide
Show/Hide
|
C22H23N7O
|
2
|
| 1 |
EC50 = 2148 nM
|
|
|
| 2 |
EC50 = 13940 nM
|
|
|
|
CP0874580
|
2-(2-{[2-(4-fluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-(pyridin-2-ylmethyl)-1,3-oxazole-4-carboxamide
Show/Hide
|
C21H21FN6O2
|
2
|
| 1 |
EC50 = 2160 nM
|
|
|
| 2 |
EC50 = 12720 nM
|
|
|
|
CP0951408
|
2-(2-{[2-(7-Chloro-4-fluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C21H19ClF2N6O2
|
2
|
| 1 |
EC50 = 2180 nM
|
|
|
| 2 |
EC50 = 3150 nM
|
|
|
|
CP0944105
|
2-{1-[2-(1H-1,3-benzodiazol-2-yl)ethyl]azetidin-3-yl}-5-chloro-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C22H20ClFN6OS
|
2
|
| 1 |
EC50 = 2440 nM
|
|
|
| 2 |
EC50 = 3380 nM
|
|
|
|
CP0903144
|
1-{1-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-{5H,6H,7H-cyclopenta[b]pyridin-7-yl}-1H-pyrazole-4-carboxamide
Show/Hide
|
C24H25N7O
|
2
|
| 1 |
EC50 = 2512 nM
|
|
|
| 2 |
EC50 = 8380 nM
|
|
|
|
CP0944109
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(4,6-dimethylpyridin-3-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C22H24N6OS
|
1
|
| 1 |
EC50 = 2630 nM
|
|
|
|
CP0874594
|
2-({[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}methyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C20H22Cl3FN6OS
|
2
|
| 1 |
EC50 = 2690 nM
|
|
|
| 2 |
EC50 = 4908 nM
|
|
|
|
CP0903748
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-{5H,6H,7H-cyclopenta[b]pyridin-7-yl}-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C22H25Cl3N6OS
|
1
|
| 1 |
EC50 = 2900 nM
|
|
|
|
CP0903132
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H18ClF3N6OS
|
1
|
| 1 |
EC50 = 2920 nM
|
|
|
|
CP0905657
|
2-(2-{[(6-Fluoro-1H-1,3-benzodiazol-2-yl)methyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C20H21Cl3F2N6OS
|
2
|
| 1 |
EC50 = 2956 nM
|
|
|
| 2 |
EC50 = 4450 nM
|
|
|
|
CP0903123
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)-2-methylpropyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C23H25FN6OS
|
2
|
| 1 |
EC50 = 2966 nM
|
|
|
| 2 |
EC50 = 5700 nM
|
|
|
|
CP0854890
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(5,6,7,8-tetrahydroquinolin-8-yl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C23H24N6OS
|
1
|
| 1 |
EC50 = 2980 nM
|
|
|
|
CP0904080
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-(pyridazin-3-ylmethyl)-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C20H24Cl3N7OS
|
2
|
| 1 |
EC50 = 3015 nM
|
|
|
| 2 |
EC50 = 4330 nM
|
|
|
|
CP0909889
|
N-[(3,5-Difluoropyridin-2-yl)methyl]-2-(2-{[2-(5-fluoro-1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C21H22Cl3F3N6OS
|
2
|
| 1 |
EC50 = 3040 nM
|
|
|
| 2 |
EC50 = 4507 nM
|
|
|
|
CP0909891
|
2-{1-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-{5H,6H,7H-cyclopenta[b]pyridin-7-yl}-1,3-thiazole-4-carboxamide
Show/Hide
|
C24H24N6OS
|
2
|
| 1 |
EC50 = 3220 nM
|
|
|
| 2 |
EC50 = 8050 nM
|
|
|
|
CP0880276
|
2-{1-[2-(1H-1,3-Benzodiazol-2-yl)ethyl]azetidin-3-yl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C22H21FN6OS
|
2
|
| 1 |
EC50 = 3640 nM
|
|
|
| 2 |
EC50 = 3946 nM
|
|
|
|
CP0903110
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl](methyl)amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C22H26Cl3FN6OS
|
2
|
| 1 |
EC50 = 3775 nM
|
|
|
| 2 |
EC50 = 13470 nM
|
|
|
|
CP0905658
|
3-({[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}methyl)-N-[(3-fluoropyridin-2-yl)methyl]-1-methyl-1H-pyrazole-5-carboxamide
Show/Hide
|
C21H22FN7O
|
2
|
| 1 |
EC50 = 3820 nM
|
|
|
| 2 |
EC50 = 17000 nM
|
|
|
|
CP0887767
|
4-({[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}methyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-2-carboxamide
Show/Hide
|
C20H19FN6OS
|
2
|
| 1 |
EC50 = 3830 nM
|
|
|
| 2 |
EC50 = 11115 nM
|
|
|
|
CP0909893
|
2-(2-{[2-(1H-1,3-benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(5-methylpyrimidin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C21H26Cl3N7OS
|
2
|
| 1 |
EC50 = 3954 nM
|
|
|
| 2 |
EC50 = 8170 nM
|
|
|
|
CP0957783
|
1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-chloropyridin-2-yl)methyl]-1H-1,2,4-triazole-3-carboxamide
Show/Hide
|
C19H19ClN8O
|
1
|
| 1 |
EC50 = 3960 nM
|
|
|
|
CP0909886
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(6-methylpyridazin-3-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C21H26Cl3N7OS
|
2
|
| 1 |
EC50 = 3960 nM
|
|
|
| 2 |
EC50 = 7730 nM
|
|
|
|
CP0946477
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-methylpyridin-4-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C21H25Cl3N6OS
|
1
|
| 1 |
EC50 = 4030 nM
|
|
|
|
CP0874592
|
2-{3-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]propyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C21H24Cl3FN6OS
|
2
|
| 1 |
EC50 = 4090 nM
|
|
|
| 2 |
EC50 = 5194 nM
|
|
|
|
CP0957785
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3,5-difluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H18F2N6OS
|
1
|
| 1 |
EC50 = 4120 nM
|
|
|
|
CP0903129
|
1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1H-1,2,4-triazole-3-carboxamide
Show/Hide
|
C19H19FN8O
|
2
|
| 1 |
EC50 = 4121 nM
|
|
|
| 2 |
EC50 = 8230 nM
|
|
|
|
CP0874578
|
2-[(1R,5S,6S)-3-(1H-1,3-Benzodiazol-2-ylmethyl)-3-azabicyclo[3.1.0]hexan-6-yl]-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C23H24Cl3FN6OS
|
1
|
| 1 |
EC50 = 4140 nM
|
|
|
|
CP0909885
|
2-{1-[2-(1H-1,3-benzodiazol-2-yl)ethyl]-3-hydroxyazetidin-3-yl}-5-chloro-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C22H20ClFN6O2S
|
2
|
| 1 |
EC50 = 4430 nM
|
|
|
| 2 |
EC50 = 6100 nM
|
|
|
|
CP0874593
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-(pyrimidin-2-ylmethyl)-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C20H24Cl3N7OS
|
2
|
| 1 |
EC50 = 4464 nM
|
|
|
| 2 |
EC50 = 10560 nM
|
|
|
|
CP0951422
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(1-methyl-1H-imidazol-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C19H21N7OS
|
1
|
| 1 |
EC50 = 4530 nM
|
|
|
|
CP0942112
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-5-(trifluoromethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C22H20F4N6OS
|
2
|
| 1 |
EC50 = 4940 nM
|
|
|
| 2 |
EC50 = 5059 nM
|
|
|
|
CP0941165
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-4-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H19FN6OS
|
1
|
| 1 |
EC50 = 5050 nM
|
|
|
|
CP0960686
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-5-chloro-N-(pyridazin-3-ylmethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C19H18ClN7OS
|
2
|
| 1 |
EC50 = 5300 nM
|
|
|
| 2 |
EC50 = 17180 nM
|
|
|
|
CP0887763
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(pyridine-2-ylmethyl)-1,3-oxazole-4-carboxamid
Show/Hide
|
C20H20N6O2
|
2
|
| 1 |
EC50 = 5750 nM
|
|
|
| 2 |
EC50 = 11073 nM
|
|
|
|
CP0871769
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-{[2-(morpholine-4-sulfonyl)phenyl]methyl}-1,3-thiazole-4-carboxamide
Show/Hide
|
C25H28N6O4S2
|
1
|
| 1 |
EC50 = 6000 nM
|
|
|
|
CP0903147
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(1,5-dimethyl-1H-pyrazol-4-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H23N7OS
|
1
|
| 1 |
EC50 = 6560 nM
|
|
|
|
CP0942113
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-5-chloro-N-[(5-methylpyrimidin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H22ClN7OS
|
2
|
| 1 |
EC50 = 6840 nM
|
|
|
| 2 |
EC50 = 23692 nM
|
|
|
|
CP0954513
|
2-{2-[(3-Aminopropyl)[2-(1H-1,3-benzodiazol-2-yl)ethyl]amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C24H28FN7OS
|
1
|
| 1 |
EC50 = 7411 nM
|
|
|
|
CP0938647
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl](butyl)amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C25H29FN6OS
|
1
|
| 1 |
EC50 = 7862 nM
|
|
|
|
CP0854891
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-{[3-(trifluoromethyl)pyridin-2-yl]methyl}-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H19F3N6OS
|
1
|
| 1 |
EC50 = 7920 nM
|
|
|
|
CP0903750
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(pyridin-2-ylmethyl)-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C20H23Cl3N6OS
|
1
|
| 1 |
EC50 = 8270 nM
|
|
|
|
CP0957776
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]-2-methylpropyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C22H23FN6OS
|
1
|
| 1 |
EC50 = 8330 nM
|
|
|
|
CP0877275
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(6-cyanopyridin-3-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H19N7OS
|
1
|
| 1 |
EC50 = 10380 nM
|
|
|
|
CP0953916
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-{[2-(4-methylpiperazin-1-yl)phenyl]methyl}-1,3-thiazole-4-carboxamide
Show/Hide
|
C26H31N7OS
|
1
|
| 1 |
EC50 = 10400 nM
|
|
|
|
CP0880279
|
1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide
Show/Hide
|
C21H19F4N7O
|
2
|
| 1 |
EC50 = 12110 nM
|
|
|
| 2 |
EC50 = 16130 nM
|
|
|
|
CP0903756
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-5-chloro-N-(pyrimidin-2-ylmethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C19H18ClN7OS
|
1
|
| 1 |
EC50 = 12452 nM
|
|
|
|
CP0903108
|
4-(2-{[2-(1H-1,3-Benzodiazol-2-yl)-2,2-difluoroethyl]amino}ethyl)-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-2-carboxamide
Show/Hide
|
C21H19F3N6OS
|
2
|
| 1 |
EC50 = 12720 nM
|
|
|
| 2 |
EC50 = 24845 nM
|
|
|
|
CP0880283
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(1-methyl-1H-pyrazol-5-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C19H21N7OS
|
1
|
| 1 |
EC50 = 13080 nM
|
|
|
|
CP0887769
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(1-methyl-1H-imidazol-5-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C19H21N7OS
|
1
|
| 1 |
EC50 = 13150 nM
|
|
|
|
CP0944236
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(pyridazin-3-ylmethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C19H19N7OS
|
1
|
| 1 |
EC50 = 16560 nM
|
|
|
|
CP0903145
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-5-(trifluoromethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H18F4N6OS
|
1
|
| 1 |
EC50 = 16985 nM
|
|
|
|
CP0903134
|
1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(pyridin-2-ylmethyl)-1H-pyrazole-4-carboxamide
Show/Hide
|
C20H21N7O
|
1
|
| 1 |
EC50 = 17780 nM
|
|
|
|
CP0942116
|
1-[1-(1H-1,3-Benzodiazol-2-ylmethyl)azetidin-3-yl]-N-[(3-fluoropyridin-2-yl)methyl]-1H-pyrazole-4-carboxamide
Show/Hide
|
C21H20FN7O
|
2
|
| 1 |
EC50 = 17860 nM
|
|
|
| 2 |
EC50 = 20000 nM
|
|
|
|
CP0874540
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(pyrimidin-4-ylmethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C19H19N7OS
|
1
|
| 1 |
EC50 = 18310 nM
|
|
|
|
CP0948408
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(1,3-oxazol-2-ylmethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C18H18N6O2S
|
1
|
| 1 |
EC50 = 18690 nM
|
|
|
|
CP0941162
|
2-{3-[(1H-1,3-Benzodiazol-2-yl)amino]propyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H19FN6OS
|
2
|
| 1 |
EC50 = 20000 nM
|
|
|
| 2 |
EC50 = 21210 nM
|
|
|
|
CP0874585
|
2-{2-[(1H-1,3-Benzodiazol-5-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H19FN6OS
|
1
|
| 1 |
EC50 = 20000 nM
|
|
|
|
CP0909888
|
2-{2-[(1H-1,3-Benzodiazol-5-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide 2-{2-[(1H-1,3-Benzodiazol-4-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H19FN6OS
|
1
|
| 1 |
EC50 = 20000 nM
|
|
|
|
CP0903133
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(6-methylpyridazin-3-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H21N7OS
|
1
|
| 1 |
EC50 = 20550 nM
|
|
|
|
CP0874582
|
2-{2-[bis(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C28H25FN8OS
|
1
|
| 1 |
EC50 = 22000 nM
|
|
|
|
CP0874595
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(1-methyl-1H-pyrazol-3-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C19H21N7OS
|
1
|
| 1 |
EC50 = 22340 nM
|
|
|
|
CP0880281
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(2-methylpyridin-4-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H22N6OS
|
1
|
| 1 |
EC50 = 22800 nM
|
|
|
|
CP0887765
|
1-({[2-(1H-1,3-Benzodiazol-2-yl)ethyl]carbamoyl}methyl)-N-[(3-fluoropyridin-2-yl)methyl]-1H-pyrazole-4-carboxamide dihydrochloride
Show/Hide
|
C21H22Cl2FN7O2
|
1
|
| 1 |
EC50 = 25000 nM
|
|
|
|
CP0959235
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(5-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C20H19FN6OS
|
1
|
| 1 |
EC50 = 30950 nM
|
|
|
|
CP0903681
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(2-fluorophenyl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H20FN5OS
|
1
|
| 1 |
EC50 = 32330 nM
|
|
|
|
CP0880277
|
2-(2-{[2-(1H-1,3-Benzodiazol-2-yl)ethyl]amino}ethyl)-5-methyl-N-(pyrimidin-2-ylmethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H23N7OS
|
2
|
| 1 |
EC50 = 35985 nM
|
|
|
| 2 |
EC50 = 39070 nM
|
|
|
|
CP0903141
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(6-methylpyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide
Show/Hide
|
C21H22N6OS
|
1
|
| 1 |
EC50 = 36260 nM
|
|
|
|
CP0904108
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(pyrimidin-2-ylmethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C19H19N7OS
|
1
|
| 1 |
EC50 = 37460 nM
|
|
|
|
CP0912267
|
2-{2-[(1,3-Benzoxazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide trihydrochloride
Show/Hide
|
C20H21Cl3FN5O2S
|
1
|
| 1 |
EC50 = 38250 nM
|
|
|
|
CP0874576
|
2-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-(pyrazin-2-ylmethyl)-1,3-thiazole-4-carboxamide
Show/Hide
|
C19H19N7OS
|
1
|
| 1 |
EC50 = 38670 nM
|
|
|
|
CP0903126
|
1-{2-[(1H-1,3-Benzodiazol-2-ylmethyl)amino]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-3,5-dimethyl-1H-pyrazole-4-carboxamide
Show/Hide
|
C22H24FN7O
|
1
|
| 1 |
EC50 = 39745 nM
|
|
|
|
CP0954514
|
2-{2-[2-(1H-1,3-Benzodiazol-2-yl)acetamido]ethyl}-N-[(3-fluoropyridin-2-yl)methyl]-1,3-thiazole-4-carboxamide dihydrochloride
Show/Hide
|
C21H21Cl2FN6O2S
|
1
|
| 1 |
EC50 = 41330 nM
|
|
|
|
CP0401015
|
(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-8,26-dibenzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28,37-octazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide
Show/Hide
|
C53H74N16O9S3
|
1
|
| 1 |
EC50 > 600 nM
|
|
|
|
CP0401062
|
N-[(2S)-1-[[(8S,11S,14R,17S,20R)-8-benzyl-11,17-bis[3-(diaminomethylideneamino)propyl]-7,10,13,16,19-pentaoxo-14-(sulfanylmethyl)-3,22-dithia-6,9,12,15,18-pentazabicyclo[22.3.1]octacosa-1(28),24,26-trien-20-yl]amino]-1-oxo-3,3-diphenylpropan-2-yl]hexadecanamide
Show/Hide
|
C68H99N13O7S3
|
1
|
| 1 |
EC50 > 600 nM
|
|
|
|
CP0413867
|
(3S,6R,19R,22S,25S,28R,31S,34S)-6-acetamido-3,22-dibenzyl-25,31-bis[3-(diaminomethylideneamino)propyl]-2,5,10,15,21,24,27,30,33-nonaoxo-28-(sulfanylmethyl)-8,17-dithia-1,4,11,14,20,23,26,29,32-nonazabicyclo[32.3.0]heptatriacontane-19-carboxamide
Show/Hide
|
C52H77N17O11S3
|
1
|
| 1 |
EC50 > 600 nM
|
|
|
|
CP0456830
|
(5R,8S,14S,17S,20R,23S,26S,29R)-8-benzhydryl-26-benzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-5-(hexadecanoylamino)-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatricyclo[31.3.1.010,14]heptatriaconta-1(37),33,35-triene-29-carboxamide
Show/Hide
|
C74H107N15O9S3
|
1
|
| 1 |
EC50 > 600 nM
|
|
|
|
CP0460309
|
(7R,10S,16S,19S,22R,25S,31R,34S,40S,43S,46R,49S,52S,55R)-7-acetamido-10,28,34,52-tetrabenzyl-19,25,43,49-tetrakis(3-carbamimidamidopropyl)-8,11,17,20,23,26,29,32,35,41,44,47,50,53-tetradecaoxo-22,46-bis(sulfanylmethyl)-5,57,62-trithia-9,12,18,21,24,27,30,33,36,42,45,48,51,54-tetradecazapentacyclo[29.29.3.13,59.012,16.036,40]tetrahexaconta-1,3(64),59-triene-55-carboxamide
Show/Hide
|
C96H134N28O16S5
|
1
|
| 1 |
EC50 > 600 nM
|
|
|
|
CP0477256
|
(3S,6R,11R,14S,17S,20R,23S,26S)-6-acetamido-3,14-dibenzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-2,5,13,16,19,22,25-heptaoxo-20-(sulfanylmethyl)-8,9-dithia-1,4,12,15,18,21,24-heptazabicyclo[24.3.0]nonacosane-11-carboxamide
Show/Hide
|
C46H67N15O9S3
|
1
|
| 1 |
EC50 > 600 nM
|
|
|
|
CP0482720
|
(5R,8S,14S,17S,20R,23S,26S,29R)-5-acetamido-8,26-dibenzyl-17,23-bis[3-(diaminomethylideneamino)propyl]-6,9,15,18,21,24,27-heptaoxo-20-(sulfanylmethyl)-3,31-dithia-7,10,16,19,22,25,28-heptazatetracyclo[31.7.1.010,14.037,41]hentetraconta-1(40),33,35,37(41),38-pentaene-29-carboxamide
Show/Hide
|
C58H77N15O9S3
|
1
|
| 1 |
EC50 > 600 nM
|
|
|
|
CP0482721
|
(3S,6R,16R,19S,22S,25R,28S,31S)-6-acetamido-3,19-dibenzyl-22,28-bis[3-(diaminomethylideneamino)propyl]-2,5,11,11,18,21,24,27,30-nonaoxo-25-(sulfanylmethyl)-8,11lambda6,14-trithia-1,4,17,20,23,26,29-heptazabicyclo[29.3.0]tetratriacontane-16-carboxamide
Show/Hide
|
C50H75N15O11S4
|
1
|
| 1 |
EC50 > 600 nM
|
|
|
|
CP0961591
|
(8R,11S,17S,20S,23R,26S,29S,32R,35S,41S,44S,47R,50S,53S,56R,59S,65S,68R,71R,74S,77S,80R)-8-acetamido-11,29,35,53,59,77-hexabenzyl-20,26,44,50,68,74-hexakis(3-carbamimidamidopropyl)-4,9,12,18,21,24,27,30,33,36,42,45,48,51,54,57,60,66,69,72,75,78,84,89,96-pentacosaoxo-23,47,71-tris(sulfanylmethyl)-3,85,88,97-tetraoxa-6,82,91,94-tetrathia-10,13,19,22,25,28,34,37,43,46,49,52,55,58,61,67,70,73,76,79-icosazahexacyclo[54.30.6.61,32.013,17.037,41.061,65]octanonacontane-80-carboxamide
Show/Hide
|
C142H200N40O31S7
|
1
|
| 1 |
EC50 > 600 nM
|
|
|
